• Applied Chemistry for Engineering
• /
• v.32 no.5
• /
• pp.509-515
• /
• 2021

In this study, poly lactic-co-glycolic acid (PLGA) nanoparticles (PNP) were prepared through double (w/o/w) emlusion and emulsifying solvent-evaporation technique using PLGA, which has biocompatibility and biodegradability. To maximize stability and bioavailability of the particles, chitosan-coated PLGA nanoparticles (CPNP) were prepared by charge interaction between PNP and chitosan. We demonstrated that CPNP can be utilized as a drug carrier of oral administration. The chemical structure of CPNP was analyzed by ¹H-NMR and FT-IR, and all characteristic peaks appeared, confirming that it was successfully prepared. In addition, particle size and zeta potential of CPNP were analyzed using dynamic light scattering (DLS) while morphological images were obtained using transmission electron microscope (TEM). Thermal decomposition behavior of CPNP was observed through thermogravimetric analysis (TGA). In addition, the cytotoxicity of CPNP was confirmed by MTT assay at HEK293 and L929 cell lines, and it was proved that there is no toxicity confirmed by the cell viability of above 70% at all concentrations. These results suggest that the CPNP developed in this study may be used as an oral drug delivery carrier.

• Journal of agriculture & life science
• /
• v.53 no.4
• /
• pp.113-124
• /
• 2019

In this study, the operational characteristics of a cam-type vegetable transplanter which usually used in domestic was analyzed and operating mechanism of a transplanting device was analyzed. The main components and power path of the transplanter were analyzed. The maximum and minimum control cycles according to the moving speed and the plant spacing were analyzed. 3D modeling and simulation were performed to derive the trajectory of the bottom end of the transplanting hopper and the plant spacing at the each operating condition. The simulation results were verified by the field tests. As main findings of this study, the transplanting device has one degree of freedom (DOF) which consist of 13 links, 17 rotating joints and 1 half joint, and each part has composite structure with cam and links. By continuous and repetitive motion of the structures of transplanting device, the transplanting hopper plants the seedling in the ground with a vertical direction, and the seedling was planted stably. The power is transmitted to the driving part and transplanting device from the engine, and the maximum and minimum plant spacing of the transplanting device were about 900 mm and 350 mm, respectively.

• Journal of the Korean Society of Radiology
• /
• v.16 no.5
• /
• pp.603-609
• /
• 2022

The dose distribution in the human body was evaluated and analyzed through dosimetry data using water phantom, ionization chamber and simulated by Monte Carlo simulation for ^99mTc and ¹⁸F sources, which are frequently used in the nuclear medicine in this study. As a result of this study, it was found that the dose decreased exponentially as the distance from the radioisotope increased, and it particularly showed a tendency to decrease sharply when the radioisotope was separated by 5 cm. It means that a large amount of dose is delivered to an organ located within 4 cm of source's movement path when a source uptake in the human body. Numerically, it was formed in the rage of 0.16 to 2.16 pC/min for ^99mTc and 0.49 to 9.29 pC/min for ¹⁸F. In addition, the energy transfer coefficient calculated using the result was found to be similar to the measured value and the simulation value in the range of 0.240 to 0.260. Especially, when the measured data and the simulation value were compared, there was a difference is within 2%, so the reliability of the data was secured. In this study, the distribution of radiation generated from a source was calculated to quantitatively evaluate the internal dose by radioisotopes. It presented reliable results through comparative analysis of the measurement value and simulation value. Above all, it has a great significance to the point that it was presented by directly measuring the distribution of radiation in the human body.

• Journal of the Society of Disaster Information
• /
• v.19 no.1
• /
• pp.161-172
• /
• 2023

Safety education delivered to construction workers in a lecture manner has limitations in concentration and immersion, so delivery power and interest are low. In order to improve unstable behavior through education and prevent safety accidents, it is necessary to change the paradigm to hands-on education. Purpose: Experiential safety education aims to contribute to preventing accidents for construction workers by quickly recognizing risks, improving emergency response skills, and verifying the effectiveness of pre- and post-learning. Method: Based on a survey of workers who experienced the same work environment as the actual construction site, an opinion survey on the pre- and post-safety experience education and a variable measurement tool were planned, and a research hypothesis was established. Results: The Bayesian theory and MC simulation analysis were used to analyze the structural equation model, and the change in construction worker behavior was confirmed through the intended safety (A), non-experiential education in the sub-area of anxiety (B), average, standard deviation, and minimum and maximum values. Conclusion: The effect of education and industrial accidents are reduced only when construction workers are motivated to participate.

• The Journal of the Acoustical Society of Korea
• /
• v.33 no.4
• /
• pp.255-261
• /
• 2014

This paper presents an underwater acoustic communication with nonlinear chirp modulation. The information is carried by the carrier amplitude, frequency or phase in the most common underwater acoustic communications. However, the proposed method includes the information within frequency variation of carrier wave for a symbol. Especially, as carrier wave the hyperbolic frequency modulated signal, one of the nonlinear chirp signal, is used and it is robust in the Doppler channel. The proposed method was analyzed and compared to conventional method by simulation. When the doppler shift existed, the error probability of the proposed method is reduced by 5~12 % than conventional method with linear frequency modulated signal. Sea trial was performed to analyze the performance of the proposed method.

• The Journal of the Institute of Internet, Broadcasting and Communication
• /
• v.12 no.2
• /
• pp.181-188
• /
• 2012

In this paper, the measurement data is analyzed and channel parameters are derived through MIMO Channel measurements at 781MHz considering outdoor multi-path environment. 781MHz frequency band currently operates the DTV system. However, it will be allocated new mobile communication frequency band. The channel characteristics at 781MHz seem to be similar existing mobile communication system at 900MHz but a study on channel characteristics of signal transfer process is necessary because there is incomplete study in mobile networks at 781MHz. To avoid interference with Korean DTV broadcasting, we measured channel characteristics in city/suburban areas of Jeju island by channel sounder and $4{\times}4$ antenna of the ETRI(Korea Electronics and Telecommunications Research Institute). Path Loss, Delay Spread, Angular Spread and K-factor were derived based on measured data.

• Transactions of the Korean Society of Automotive Engineers
• /
• v.20 no.3
• /
• pp.119-125
• /
• 2012

Caliper intergrated Electric Parking Brake (EPB) is an automatic parking brake system, attached to rear caliper. Because EPB uses luxury vehicles recently, the drivers of vehicles are sensitive to the EPB noise. EPB is operated by the motor and gear, so noise is generated by motor and gear. In order to reduce noise, One of EPB manufacturers uses helical gear and changes the shape of EPB housing. But these methods are not optimized for reduction of interior noise. There are many noise transfer paths into vehicle interior and it is difficult to identify the noise sources. Therefore, in this study, we performed contribution analysis and modal testing in the vehicle system. It is possible to distinguish between air-borne noise and structure-borne noise in the vehicle interior noise by comparing interior noise peak with resonance mode map.

• Archives of design research
• /
• v.16 no.2
• /
• pp.77-86
• /
• 2003

In web environment, we accept most of useful information visually. Icon is a channel through which we explore information, and we need icon design to deliver information clearly and quickly to users who accept information visually. Studies on icon have been carried out vigorously according to system environment, styles and characteristics of users. This study is on the metaphor icon, and judging from the characteristics of metaphor icon, it is by the phenomena of user's association of ideas. Divide metaphor and simile and analyzed metaphor icon that is searched in World Wide Web to distinguish similarity in metaphor icon special qualify, And I clarified the present condition of cognition by questionnaires asking people if they recognize the function. I also clarified if elements of icon design influence the level of user's cognition by visually comparing icons. The result of comparative analysis showed that different elements make different level of user's cognition, and to objectify it more, I made up questionnaires about elements of icon design and proved it again. To summarize the result of this study, the similarity between function and elements of design increases the level of recognition of metaphor icon proportionally. To improve user's cognition, I suggest designing with elements which materialize functions.

• Journal of the Korean Society for Nondestructive Testing
• /
• v.27 no.1
• /
• pp.1-7
• /
• 2007

As fiber reinforced composite materials are widely used in aircraft, space structures and robot arms, the study on non-destructive testing methods has become an important research area for improving their reliability and safety. AE (acoustic emission) can evaluate the defects by detecting the emitting strain energy when elastic waves are generated by the initiation and growth of crack, plastic deformation, fiber breakage, matrix cleavage, or delamination. In the paper, AE signals generated under uniaxial tension were measured and analyzed using the $8{\times}8$ matrix piezo electric sensor. The electronic circuit to control the transmitting distance of AE signals was designed and constructed. The optical data storage system was also designed to store the AE signal of 64channels using LED (light emitting diode) elements. From the tests, it was shown that the source location and propagation path of AE signals in composite materials could be detected effectively by the $8{\times}8$ matrix piezo electric sensor.

• Journal of the Korea Society of Computer and Information
• /
• v.18 no.10
• /
• pp.47-54
• /
• 2013

In this paper, the structural design of optical Internet is analyzed and by using UNI (User Network Interface) signaling protocol an optical transmission experiment was performed. The hierarchical structure of the basic optical Internet consists of the backbone network, the service network and the access network. The necessary functions for each layer were described as follows: Control structure of the optical transport layer, network operation and management structure, internetworking technology of sub networks, routing and signaling technology. By using UNI signaling protocol from OIF (Optical Internetworking Forum), the optical transmission in the proposed structure of the optical Internet network was experimented. By the traffic generation of LSP (Label Switched Path) data packets along the route-configuration was delivered to UNI. Finally, by showing the value of TCP (Transmission Control Protocol) packets the optical transmission was completely and successfully demonstrated.