• Korean journal of applied entomology
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• v.33 no.1
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• pp.19-25
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• 1994

Electrophysiological recordings of antennal responses to common plant volatile chemicals in the rice brown planthopper, Niloparuota lugens (Homoptera: Delphasidae}, were examined. Volatile plant chemicals were generally credited with a major role In host plant location for food or egg laying by many insects feeding on plants as adults and/or as larvae. An mitial examination of extracellular responses has been conducted. Acton potentials recorded from the plaque organs were initially positive-going, biphaslc spikes and the background firing rate of the cells recorded ranged from 1 ~22 impulses/sec. A wide range of responses to changes in concentration of the test chemical was observed. The commonest response was a relatively small increase in exitation with increasing concentration beween 1 J.lg and 100).\g on the filter paper in syringe. Adtivity either peaked at 100 $\mug$ and remained virtually saturated at 1000 f19 or tended to decrease at the highest concentration.

• The Journal of Korean Academy of Sensory Integration
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• v.9 no.1
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• pp.45-52
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• 2011

Objective : The aim of this study was to provide the method to measure physiologic response using equipments and auditory stimulation, and the physiologic response features of adult psychiatric disorders through a systemic review. Methods : The systemic review was executed using PubMed. The key words for search were "auditory stimulation, auditory startle, electromyograph, skin conductance, heart rate, psychiatric disorder, anxiety disorder, schizophrenia, depression". 8 studies were used for data analysis, and all of levels of evidence were level II. The substances of the review were subject(population), auditory stimulation, measure equipments and physiologic response features of psychiatric disorder. Results : 1. The subjects for the studies were anxiety disorder(4) and schizophrenia(4). 2. Auditory stimulation was used in 8 studies and visual stimulation with auditory stimulation was used in 2 studies to induce physiologic response. 3. Every study used electromyograph, and skin conductance was used in 2 studies and heart rate was used in 2 studies with electromyograph to measure physiologic response. 4. The subjects for the studies, schizophrenia and anxiety disorder(PTSD, OCD) have different physiologic response features with the normal control group. Conclusion : All studies used simple tones as an auditory stimulation and electromyograph to measure physiologic response. Psychiatric disorders indicated larger response, shorter and delayed habituation. The objective and systematic study using physiologic measure to investigate the sensory feature of psychologic disorders.

• Proceedings of the Korean Society of Applied Pharmacology
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• 1994.04a
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• pp.231-231
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• 1994

이 연구는 인삼 성분 약물이 도파민 수용체에 미치는 영향을 연구하기 위한 첫 단계로써 그 기본적인 assay system을 정착 시키기 위함이 목적이었다. 우리는 이 연구를 수행하기 위하여 생후 2-4 일의 쥐를 사용하여 흑질, 선조체, 해마구, nucleus accumbens등의 뇌 부위에서 신경세포 배양을 시도하였다. 흑질로 부터 배양한 신경세포들의 경우엔 면역 세포학적방법을 써서 살펴본 결과 대부분의 신경이 도파민성 신경이나 GABA성 신경들 이었다. 또한 이들 세포들의 전기 생리학적 상태를 알아보기 위하여 흑질에서 신호 전달체계가 잘 확립된 GABA 수용체의 작용을 살펴 본 결과 이 신경세포들은 GABA-A 및 GABA-B 수용체의 발현은 물론 이온 채널에 미치는 신호 전달체계를 완전히 갖추고 있었다. 도파민 수용체의 작용을 전기 생리학적으로 연구하기 위하여 배양한 신경세포에 도파민agonist를 가해서 이온 채널에 미치는 효과를 살펴 보았다. 선조체에서 배양한 신경세포들은 Dl 과 D2 agonist에 대해서 상반되는 반응을 나타냈다. 즉 Dl agonist는 선조체 신경세포를 활성화 시켰으나 D2 agonist는 선조체 신경세포들을 억제 하였다. 한편 해마구의 CAI 과 CA3 부위로 부터 배양한 신경세포에 대한 도파민 agonists의 작용은 선조체의 신경세포에 대한도파민 agonists의 작용과는 상반되는 반응 이었다. Dl agonist는 해마구로 부터 배양한 신경세포의 활성을 억제 하였으나 D2 agonist는 이들 신경세포들의 활성을 증가 시켰다. Nucleus accumbens 에서 배양한 신경세포들은 도파민에 의해서 그 활성이 억제 되었다. 이러한 결과로 미루어 봐서 같은 도파민 수용체라도 분포되어 있는 조직에 따라서 신호전달 에 관여 하고 있는 C-단백이나 이차 전령물질이 달라서 신경세포에 대한 작용이 다르든지. 약리학적으로는 구분되지 않으나 뇌의 조직에 따라서 분포가 다른 도파민 수용체의 아그룹이 존재 한다고 생각된다.

• Therapeutic Science for Rehabilitation
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• v.1 no.1
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• pp.5-16
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• 2012

Sensory integration started as a theory to provide a occupational therapist with a useful frame for explaining and intervening the problems which children have. Most researches on sensory processing disorder (SPD) have been found empirical evidence to support the sensory integration theory by measuring behavioral manifestations of SPD. Recently, researchers who are interested in the diagnosis of SPD have begun to use neurophysiological methods to establish objective evidence for sensory integration. These studies reported the neurophysiological indexes reflecting the maladaptive behaviors as well as the difference between children with SPD and typically developing children in using electrodermal activity, vagal tone, EEG. Future neurophysiological studies on SPD will be expected to prove the efficacy of sensory integration intervention.

• The Journal of the Acoustical Society of Korea
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• v.35 no.1
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• pp.63-73
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• 2016

It is widely acknowledged that the human auditory system is organized tonotopically and people generally listen to sounds as a function of frequency distribution through the auditory system. However, it is still unclear how acoustic features of speech sounds are indicated to the human brain in terms of speech perception. Thus, the purpose of this study is to investigate whether two sounds with similar high-frequency characteristics in the acoustic analysis show similar results at the level of auditory brainstem. Thirty three young adults with normal hearing participated in the study. As stimuli, two Korean monosyllables (i.e., /ja/ and /cha/) and four frequencies of toneburst (i.e., 500, 1000, 2000, and 4000 Hz) were used to elicit the auditory brainstem response (ABR). Measures of monosyllable and toneburst were highly replicable and the wave V of waveform was detectable in all subjects. In the results of Pearson correlation analysis, the /ja/ syllable had a high correlation with 4000 Hz of toneburst which means that its acoustic characteristics (i.e., 3671~5384 Hz) showed the same results in the brainstem. However, the /cha/ syllable had a high correlation with 1000 and 2000 Hz of toneburst although it has acoustical distribution of 3362~5412 Hz. We concluded that there was disagreement between acoustic features and physiology outcomes at the auditory brainstem level. This finding suggests that an acoustical-perceptual mapping study is needed to scrutinize human speech perception.

• Parasites, Hosts and Diseases
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• v.30 no.2
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• pp.91-100
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• 1992

Tissue origin of individual component proteins in crude extract of adult Paragonimus westermani was investigated. Major soluble component proteins were separated by disc-PAGE in 8% slab gel. By predefined Rf values, strips of gel containing each band protein was cut out. Each band protein was eluted by electrophoresis. Monospecific antibodies were prepared by immunizing rabbits with each band protein. When peroxidase-antiperoxidase (PAP) staining was done, antiserum to Band 1 reacted to content of eggs both in the worm and in the infected lung tissue. Antiserum to Band 2 reacted to parenchymal tissue of the worm. Antiserum to Band 4 showed the positive reaction at intestinal content while that to Band 5 reacted to the intestinal epithelial border. Antiserum to combined proteins of Bands 617 and that to Band 8 reacted to parenchymal tissue of the worm respectively. From the results, the origin of individual proteins in crude extract of adult P. westermani could be differentiated.

• Korean Journal of Clinical Laboratory Science
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• v.51 no.4
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• pp.462-467
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• 2019

Many studies in recent decades have revealed that olfactory stimulation by perfume or malodor inhalation exerts various psychological and physiological effects on humans. The most recent studies have examined the electrophysiological response of olfactory stimulation on the activity of human cortical nerve cells. The purpose of this current study is to quantitatively analyze what changes occur in the alpha activity in healthy participants (N=12) on olfactory stimulation using two types of odors (acacia and butanol). Exposure to the odor of acacia perfume was associated with a significant increase (66.7%) in alpha activity when compared with that of the no-odor background EEG. Exposure to the odor of butanol was associated with a significant reduction (33.3% to 41.7%) in EEG alpha activity when compared with that of the no-odor control. The results of this study demonstrated the potential to alter the cerebral cortex activity by olfactory stimulation. The results also suggest that olfactory perception has stimulatory effects on the function of the nervous system. In other words, it could be concluded from this study that inhalation of olfactory stimulation affected brain wave activities and mood states. Further research is needed to completely understand and describe the electrophysiological effects of different odors on the central nervous system.

• Parasites, Hosts and Diseases
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• v.26 no.3
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• pp.163-168
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• 1988

To observe the antigenic protein fractions in saline extract of Spirometra mansoni plerocercoid (sparganum), the crude extract was separated in reducing conditions of sodium dodecyl sulfate-polyacrylamide gel electrophoresis(SDS-PAGE). The proteins, transferred by celctrophoresis to introcillulose paper, were reacted with sera from 15 surgically confirmed sparganosis and 24 cysticercosis patients for immunoblotting. Out of 30 identified protein bands in the extract, bands of 29 and 36 kilodaltons (kDa) were the strongest and the most frequently reacting with specific antibody (IgG) in sparganosis sera. Bands of highter molecular weight also reacted with the sera but their frequency of reactions was lower. Sera of cysticercosis reacted with different protein bands in saline extract of sparganum, but the cross reactions were observed in strong antigenic bands of 29 and 36 kDa.

• 전기의세계
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• v.35 no.12
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• pp.782-788
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• 1986

전기는 오늘날 문명사회의 기초에너지로서 여러방면에서 이용되고 있으며 전기의 이용없이는 우리들의 문화생활과 산업활동은 있을 수 없다. 이와같이 없어서는 안될 전기도 한편으로는 매우 큰 위험성을 내포하고 있다. 그것은 전기가 인체에 흐름에 따라 발생하는 감전이라는 현상이며, 이러한 경우 어떤 때에는 중대한 감전재해가 발생하기도 한다. 감전재해는 전기가 갖는 위험성을 모른다거나, 혹은 위험성에 대한 인식이 부족함으로 일어나는 경우가 대부분이다. 그러므로, 전기가 갖는 위험성을 정확히 인식하고, 감전재해를 일으키지 않으며 전기를 이용하기 위해서 안전수칙, 접지공사등 여러가지의 대처방안을 이룩하여 안전을 도모하여야 한다. 본고에서는, 먼저 감전에 대한 인체의 생리학적 반응을 기술한 후 전기설비주위에서 발생하기 쉬운 감전사고를 방지하기 위한 대처방안으로서 지락보호에 대해 해설하고자 한다. 지락보호에는 그 계통의 접지방식에 따라 보호접지방식, 과전류차단방식, 누전경보방식, 절연변압기방식, 누전차단방식등이 있으며, 이들은 각각 나름대로의특징이 있으나 주로 누전차단 방식이 다른 것에 비해 적절하며, 세계적으로도 지락보호대책으로 보안효과를 높일 수 있는 누전차단기를 채용하고 있는 실정에 있다.

• Proceedings of the KIEE Conference
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• 2011.07a
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• pp.1970-1971
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• 2011

정서인식분야에서 현재 활발히 연구되고 있는 방법은 다양한 생체신호를 통해 인간의 감정을 인식하는 것이다. 생리심리학적 연구에서 인간의 감정상태와 생체반응은 강한 상관이 있다고 알려져 있다. 생체신호는 센서 등으로 비교적 간단하게 획득할 수 있으며, 이를 이용한 감정인식은 사회적, 문화적인 차이에 덜 민감하므로 최근에 주목 받고 있다. 본 연구에서는 audio-visual film clips 자극으로 기쁨, 분노, 놀람, 스트레스 4종류의 정서를 유발하고 그에 대한 반응으로써 생체신호를 측정하였다. 그리고 생체신호로부터 feature를 추출하였고, 주성분분석(PCA)로 특징 축소를 수행하였다. 4가지 정서를 분류 한 결과, 9명의 가우시안 프로세스 분류기에 의한 평균 정서 판별율은 64.85 % (57.14~70.0)의 결과를 얻었다.