• Title/Summary/Keyword: 재현성 및 선량평가

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CT and MRI Image Fusion Reproducibility and Dose Assessment on Treatment Planning System (치료계획시스템에서 전산화단층촬영과 자기공명영상의 영상융합 재현성 및 선량평가)

  • Choi, Jae-Hyock;Park, Cheol-Soo;Seo, Jeong-Min;Cho, Jae-Hwan;Choi, Cheon-Woong
    • Journal of the Korean Magnetics Society
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    • v.24 no.6
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    • pp.191-196
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    • 2014
  • The purpose of this study is to evaluate the reproducibility and usefulness of an image through the fusion of the computed tomography image and the magnetic resonance image by using a self-produced phantom when planning the treatment, and also to compare and analyze the target dose on the acquired image. The size of small hole and the reproducibility of capacity existed in the phantom on the image of the phantom obtained by the computed tomography and the magnetic resonance image of the phantom scanning with different intensity of magnetic field are compared, and the change of dose in the random target is compared and analyzed.

3차원 조형 방사선치료계획 장비 CorePlan의 유용성 평가

  • 강영남;장지선;강대규;박성일;최일봉;유치훈;강상욱;임병완;신성균
    • Proceedings of the Korean Society of Medical Physics Conference
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    • 2003.09a
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    • pp.33-33
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    • 2003
  • 목적 : 현재 국내에서 사용되고 있는 방사선치료계획 장비는 거의 모든 방사선종양학과에서 외국 회사의 제품을 사용하고 있는 실정이다. 본 연구는 국내 기술로 개발된 3 차원 조형 방사선치료계획 장비인 Core Plan의 선량계산 알고리즘의 정확성 및 방사선 치료계획 장비로서의 유용성에 관해 평가하고 본 장비의 특징에 대해 간략히 소개하고자 한다. 재료 및 방법 : 본 연구는 2002 년 11 월에 가톨릭대학교 성모병원 방사선종양학과와 서울씨앤제이의 연구계약에 의해 시행되었다. 본 장비에 대한 평가는 방사선분포 및 계산상의 정확성과 임상적용시의 유용성의 관점에서 시행되었다. 본 장비에서 이용된 광자선 선량계산은 Clarkson-Cunningham 모델이며 전자선 선량계산은 2.5D Hogstrom 알고리즘이다. 방사선분포 및 계산상의 정확성 평가를 위하여 방사선치료 장비는 본 병원이 보유한 Clinac 2100CD (Varian, USA)를 이용하였고 폴리스티렌 팬텀과 필름 및 이온 전리함을 이용하여 방사선분포 및 계산상의 정확성을 평가하였다. 방사선분포의 평가 방법은 필름을 이용한 방사선분포의 중심부단면 선량분포와 CorePlan 에서 재현된 방사선분포의 동일면 선량분포를 비교하였다. 임상적용은 2003 년 3 월부터 7 월까지 방사선치료를 받은 50 명의 환자를 대상으로 분석하였다. 본 시험에 적용된 환자는 본 병원이 보유한 3 차원 방사선치료계획 장비인 Prowess 3D (SSGI Inc., USA)를 이용하여 실제 치료된 환자들이며 이 환자를 대상으로 CorePlan에서 동일하게 재현하여 비교하였다. 결과 및 결론 : 방사선분포 및 계산상의 정확성 평가에서는 실제 측정된 결과와 CorePlan에서 재현된 결과가 모두 $\pm$3% 이내로 평가되었다. 50 명의 환자를 대상으로 시행한 임상시험 결과 Prowess 3D에서 나타낸 결과와 비교하여 두경부에서는 1.678%, 흉부 1.578%, 복부 1.271%의 선량값의 오차를 보였다. 본 연구를 진행하는 과정에서 많은 부분의 프로그램 수정이 있었으며 실제임상에 필요한 부분에 대한 추가 및 보완이 이루어졌다. 앞으로 진행될 과정은 실제임상의 사용에 필요한 부분의 계속적인 업그레이드와 전자선에 대한 방사선분포 및 계산정확성 평가, 임상적용에 있어서 Prowess3D 뿐만 아니라 다양한 방사선 치료계획 장비와의 비교를 할 예정이다.

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Development and Evaluation of Silicon Passive Layer Dosimeter Based Lead-Monoxide for Measuring Skin Dose (피부선량 측정을 위한 Lead-Monoxide 기반의 Silicon Passive layer PbO 선량계 개발 및 평가)

  • Yang, Seung-Woo;Han, Moo-Jae;Jung, Jae-Hoon;Bae, Sang-Il;Moon, Young-Min;Park, Sung-Kwang;Kim, Jin-Young
    • Journal of the Korean Society of Radiology
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    • v.15 no.6
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    • pp.781-788
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    • 2021
  • Due to the high sensitivity to radiation, excessive exposure needs to be prevented by accurately measuring the dose irradiated to the skin during radiation therapy. Although clinical trials use dosimeters such as film, OSLD, TLD, glass dosimeter, etc. to measure skin dose, these dosimeters have difficulty in accurate dosimetry on skin curves. In this study, to solve these problems, we developed a skin dosimeter that can be attached according to human flexion and evaluated its response characteristics. For the manufacture of the dosimeter, lead oxide (PbO) with high atomic number (ZPb: 82, ZO: 8) and density (9.53 g/cm3) and silicon binders that can bend according to human flexion were used. In the case of a dosimeter made of PbO material, the performance degradation has been prevented by using parylene and others due to the presence of degradation due to oxidation, but the previously used parylene is affected by bending, so a new form of passive layer was produced and applied to the skin dosimeter. The characteristic evaluation of the skin dosimeter was evaluated by analyzing SEM, reproducibility, and linearity. Through SEM analysis, bending was evaluated, reproducibility and linearity at 6 MeV energy were evaluated, and applicability was assessed with a skin dosimeter. As a result of observing the dosimeter surface through SEM analysis, the parylene passive layer PbO dosimeter with the positive layer raised to the parylene produced cracks on the surface when bent. On the other hand, no crack was observed in the silicon passive layer PbO dosimeter, which was raised to silicon passive layer. In the reproducibility measurement results, the RSD of the silicon passive layer PbO dosimeter was 1.47% which satisfied the evaluation criteria RSD 1.5% and the linearity evaluation results showed the R2 value of 0.9990, which satisfied the evaluation criteria R2 9990. The silicon passive layer PbO dosimeter was evaluated to be applicable to skin dosimeters by demonstrating high signal stability, precision, and accuracy in reproducibility and linearity, without cracking due to bending.

Evaluate the implementation of Volumetric Modulated Arc Therapy QA in the radiation therapy treatment according to Various factors by using the Portal Dosimetry (용적변조회전 방사선치료에서 Portal Dosimetry를 이용한 선량평가의 재현성 분석)

  • Kim, Se Hyeon;Bae, Sun Myung;Seo, Dong Rin;Kang, Tae Young;Baek, Geum Mun
    • The Journal of Korean Society for Radiation Therapy
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    • v.27 no.2
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    • pp.167-174
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    • 2015
  • Purpose : The pre-treatment QA using Portal dosimetry for Volumetric Arc Therapy To analyze whether maintaining the reproducibility depending on various factors. Materials and Methods : Test was used for TrueBeam STx$^{TM}$ (Ver.1.5, Varian, USA). Varian Eclipse Treatment planning system(TPS) was used for planning with total of seven patients include head and neck cancer, lung cancer, prostate cancer, and cervical cancer was established for a Portal dosimetry QA plan. In order to measure these plans, Portal Dosimetry application (Ver.10) (Varian) and Portal Vision aS1000 Imager was used. Each Points of QA was determined by dividing, before and after morning treatment, and the after afternoon treatment ended (after 4 hours). Calibration of EPID(Dark field correction, Flood field correction, Dose normalization) was implemented before Every QA measure points. MLC initialize was implemented after each QA points and QA was retried. Also before QA measurements, Beam Ouput at the each of QA points was measured using the Water Phantom and Ionization chamber(IBA dosimetry, Germany). Results : The mean values of the Gamma pass rate(GPR, 3%, 3mm) for every patients between morning, afternoon and evening was 97.3%, 96.1%, 95.4% and the patient's showing maximum difference was 95.7%, 94.2% 93.7%. The mean value of GPR before and after EPID calibration were 95.94%, 96.01%. The mean value of Beam Output were 100.45%, 100.46%, 100.59% at each QA points. The mean value of GPR before and after MLC initialization were 95.83%, 96.40%. Conclusion : Maintain the reproducibility of the Portal Dosimetry as a VMAT QA tool required management of the various factors that can affect the dosimetry.

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Development and Feasibility Evaluation of CsPbBr3 Dosimeter for Brachytherapy (근접방사선치료용 CsPbBr3 선량계 제작 및 적용가능성 평가)

  • Yang, Seung-Woo;Park, Sung-Kwang
    • Journal of the Korean Society of Radiology
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    • v.16 no.4
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    • pp.405-410
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    • 2022
  • In brachytherapy, a radiation source is inserted into the body to kill tumor tissue. Therefore, it is important to accurately measure the location of the source and the dose distribution. In this study, a dosimeter that can be used for brachytherapy was developed using CsPbBr3 which is cheaper than the existing detector materials and has a simpler manufacturing process. The CsPbBr3 dosimeter performance was evaluated by analyzing reproducibility, linearity, and distance dependence in 192Ir source. As a result of reproducibility evaluation, the RSD was 1.36%, which satisfies the standard value of 1.5%. As a result of the linearity evaluation, the R2 value was 0.9993, which satisfies the standard R2 of 0.9990. The distance dependence evaluation showed a signal value that decreased exponentially as the distance increased. The evaluation results show that the CsPbBr3 dosimeter satisfies the evaluation criteria and can be used as a brachytherapy quality assurance dosimeter.

Evaluation of Dose Distributions calculated with ITV Measurement Plan Data and PTV Measurement plan Data under the condition of Respiratory Motion during 3D for ABD Cancer (내부표적체적 기반의 치료계획과 호흡연동 기법을 적용한 치료계획과의 선량비교 분석)

  • Park, Ho-Chun;Han, Jae-Bok;Song, Jong-Nam;Choi, Nam-Gil
    • Proceedings of the Korea Contents Association Conference
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    • 2014.11a
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    • pp.227-228
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    • 2014
  • 방사선치료의 발전으로 3차원치료보다 진보된 호흡연동방사선치료가 시행되어지고 있다. 호흡의 규칙성과 환자의 위치 재현성이 중요한 치료적응 인자이며, 호흡연동 방사선치료의 효율을 높일 수 있는 지표이다. 국가암통계상 고령의 암환자가 증가하며, 수술, 화학요법을 병행하는 암 치료법이 널리 이용이 되고 있다. 고식적인 치료를 요하는 고령의 복부 암 환자분들에 호흡연동 방사선치료법을 사용하는데 에는 호흡의 불규칙성과 체위의 재현성의 문제점으로 인한 치료 효율의 저하를 가져온다. 본 연구에서는 호흡에 의한 종양 움직임이 있는 방사선 치료에서 내부표적체적 기반의 치료계획과 호흡연동 기법을 적용한 치료계획과의 선량비교 분석하였다. 2가지 치료법 모두 정상조직 보호선량에 부합한 것으로 나타났으며 치료체적은 처방선량의 95%이상 포함된 선량분포로 적합하였다. ITV 설정을 통한 3D Plan은 고식적 치료을 목적으로 하는 고령의 환자, 체위 및 호흡의 불안정성 환자에게 처방선량의 95% 이상의 4D Plan의 치료법 보다 짧은 시간에 치료함으로써 치료효율을 높일 수 있을 거라 사료된다. 다만 정상조직보호선량(NTCP)에 부합하는지에 대한 평가가 전제되어야 한다.

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Study on Dosimetric Properties of Radiophotoluminescent Glass Rod Detector (유리선량계의 선량 특성에 관한 연구)

  • Rah, Jeong-Eun;Shin, Dong-Oh;Hong, Ju-Young;Kim, Hee-Sun;Lim, Chun-Il;Jeong, Hee-Gyo;Suh, Tea-Suk
    • Journal of Radiation Protection and Research
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    • v.31 no.4
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    • pp.181-186
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    • 2006
  • A radiophotoluminescent glass rod detector (GRD) system has recently become commercially available. We investigate the dosimetric properties of the GRD regarding the reproducibility of signal, dose linearity and energy dependence. The reproducibility of five measurements for 50 GRDs is presented by an average of one standard deviation of each GRD and it is ${\pm}1.2%$. It is found to be linear in response to doses of $^{60}Co$ beam in the range 0.5 to 50 Gy with a coefficient of linearity of 0.9998. The energy dependence of the GRD is determined by comparing the dose obtained using cylindrical chamber to that by using the GRD. The GRD response for each beam is normalized to the response for a $^{60}Co$ beam. The responses for 6 and 15 MV x-ray beams are within ${\pm}1.5%$ (1SD). The energy response of GRD for high-energy photon is almost the same as the energy dependence of LiF:Mg:Ti (TLD-100)and shows little energy dependence unlike p-type silicon diode detector. The GRDs have advantages over other detectors such diode detector, and TLD: linearity, reproducibility and energy dependency. It has been verified to be an effective device for small field dosimetry for stereotactic radiosurgery.

The Study on Applicability of Manufactured Lead(II) Iodide Dosimeter for Dose Measurement in Brachytherapy (방사선근접치료 분야의 선량 측정을 위해 제조된 Lead(II) Iodide 선량계의 적용가능성 연구)

  • Yang, Seung-Woo;Han, Moo-Jae;Park, Sung-Kwang
    • Journal of the Korean Society of Radiology
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    • v.15 no.6
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    • pp.789-794
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    • 2021
  • Brachytherapy is a treatment in which radioactive isotopes are placed inside the body to intensively irradiate the tumor with radiation. Because brachytherapy uses a radioisotope source with a high dose rate, it is very important to know the exact location and dose of the source. However, in clinical practice, it is evaluated inaccurately with the naked eye through rulers and autoradiographs. Therefore, in this study, a dosimeter that can be used for brachytherapy was developed using a lead(II) iodide (PbI2) material, and the applicability was evaluated by analyzing the reproducibility, linearity, and PID items. As a result of reproducibility evaluation, the RSD value was 1.41%, satisfying the evaluation criteria of 1.5%. As a result of the linearity evaluation, the R2 value was 0.9993, which satisfies the evaluation criterion of 0.9990. As a result of PID evaluation, it showed only a difference of 0.06 cm compared with the theoretical value of the inverse square law of distance at the 50% dose reduction point. The dosimeter manufactured in this experiment shows results that satisfy the standard in all evaluations, so it is judged that the possibility of applying the dosimeter in the radiation brachytherapy area is sufficient.

CT and MRI image fusion reproducibility and dose assessment on Treatment planning system (치료계획시스템에서 전산화단층촬영과 자기공명영상의 영상융합 재현성 및 선량평가)

  • Ahn, Byeong Hyeok;Choi, Jae Hyeok;Hwang, Jae ung;Bak, Ji yeon;Lee, Du hyeon
    • The Journal of Korean Society for Radiation Therapy
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    • v.29 no.2
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    • pp.33-41
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    • 2017
  • Objectives: The aim of this study is to evaluate the reproducibility and usefulness of the images through the fusion of CT(Computed tomography) and MRI(Magnetic resonance imaging) using a self-manufactured phantom. We will also compare and analyze the target dose from acquired images. Materials and Methods: Using a self-manufactured phantom, CT images and MRI images are acquired by 1.5T and 3.0T of different magnetic fields. The reproducibility of the size and volume of the small holes present in the phantom is compared through the image from CT and 1.5T and 3.0T MRI, and dose changes are compared and analyzed on any target. Results: 13 small hole diameters were a maximum 31 mm and a minimum 27.54 mm in the CT scan and the were measured within an average of 29.28 mm 1 % compared to actual size. 1.5 T MRI images showed a maximum 31.65 mm and a minimum 24.3 mm, the average is 28.8 mm, which is within 1 %. 3.0T MRI images showed a maximum 30.2 mm and a minimum 27.92 mm, the average is 29.41 mm, which is within 1.3 %. The dose changes in the target were 95.9-102.1 % in CT images, 93.1-101.4 % in CT-1.5T MRI fusion images, and 96-102 % in CT-3.0T MRI fusion images. Conclusion: CT and MRI are applied with different algorithms for image acquisition. Also, since the organs of the human body have different densities, image distortion may occur during image acquisition. Because these inaccurate images description affects the volume range and dose of the target, accurate volume and location of the target can prevent unnecessary doses from being exposed and errors in treatment planning. Therefore, it should be applied to the treatment plan by taking advantage of the image display algorithm possessed by CT and MRI.

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A Study on Characteristic of Glass Dosimeter According to Graded Change of Tube Current (유리선량계의 단계별 관전류량 변화에 따른 특성연구)

  • Son, Jin-Hyun;Kim, Seong-Ho;Mun, Hyun-Jun;Kim, Lyun-Kyun;Son, In-Hwa;Kim, Young-Jun;Min, Jung-Whan;Kim, Ki-Won
    • Journal of radiological science and technology
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    • v.37 no.2
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    • pp.135-141
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    • 2014
  • This study was evaluated the linearity and reproducibility according to dose, and reproducibility according to delay time by changing tube current amount (5 mAs, 10 mAs, 16 mAs, 20 mAs, 25 mAs, 32 mAs respectively, which are low energy radiations) using Glass Dosimeter (GD) and piranha semiconductor dosimeter which are used for measuring exposure dose. Measurements of radiation dose were performed using external detector of piranha 657 which is multi-function QA device (RTI Electronic, Sweden). Conditions of measurement were 80 kVp, SSD 100 cm and exposure region is $10cm{\times}10cm$. Glass dosimeter was exposed to radiation. Twenty-four glass dosimeters were divided into six groups (5 mAs, 10 mAs, 16 mAs, 20 mAs, 25 mAs, 32 mAs respectively), then measured. This study was resulted by measuring the linearity and reproducibility according to change of tube current in low energy field. In dose characteristic of GD, this study could be useful as previous study with regard to dose characteristic according to change of tube voltage in low energy field.