• Title/Summary/Keyword: 재발량

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Predictive factors for Relapse in Children with Steroid Responsive Nephrotic Syndrome (소아 스테로이드 반응성 신증후군에서 재발과 관련된 예측인자)

  • Cho Min Hyun;Lee Dong Won;Lee Tae Ho;Ko Cheol Woo
    • Childhood Kidney Diseases
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    • v.9 no.2
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    • pp.167-174
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    • 2005
  • Purpose : Relapses are a major problem in children with steroid responsive nephrotic syndrome(SRNS). This study has been performed to determine the predictive factors for relapse in children with SRNS. Methods : The study group consisted of 7,3 children with SRNS who had been admitted to the Department of Pediatrics, Kyungpook National University Hospital, over 6 years from 1996 to 2001. The medical records were reviewed retrospectively and analyzed to determine significant relationships between selected variables[age at onset, sex, laboratory data, the rapidity of response(days to remission), interval to first relapse] and the frequency of relapse. Results : The age($mean{\pm}SD$) of patients was $4.53{\pm}2.53$ years old. The male to female ratio was 52:21. In 95$\%$, 39 out of the 41 children had a renal biopsy, and the final diagnosis was minimal change nephrotic syndrome. There was no significant correlation between the frequency of relapse and the following variables age at onset, sex, and presence of hematuria. However, the rapidity of response correlated well with the frequency of relapse, especially during the first year after the onset of the disease(P=0.005). Conclusion : The rapidity of response is expected to be one of the predictive (actors for relapse in children with SRNS. (J Korean Soc Pediatr Nephrol 2005;9:167-174)

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Effects of Postoperative Radiation Therapy for Prevention of Keloids and Hypertrophic Scars (켈로이드와 비후성 반혼에서 재발을 방지하기 위한 수술후 방사선치료의 효과)

  • Kang, Ki-Mun;Choi, Ihl-Bohng;Kim, In-Ah;Jang, Jee-Young;Shinn, Kyung-Sub
    • Radiation Oncology Journal
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    • v.15 no.3
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    • pp.269-276
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    • 1997
  • Purpose : To evaluate the effects of surgical excision followed by radiation therapy for Prevention of keloids and hypertrophic scars. Materials and Methods : From October 1987 to April 1995, radiation therapy was applied to 167 sites in 106 patients with surgical excision in an attempt to prevention of recurrence against keloids and hypertrophic scars. The main etiology of the keloids and hypertrophic scars were surgery in $49.2\%,\;trauma\;in\;25.0\%,\;ear-piercing\;in\;5.4\%,\;and\;burn\;in\;5.4\%$, The Patients' ages ranged from 3 to 70 years with a median of 32 years. Radiation therapy used ranged from 6 to 8MeV electron beam. Radiation therapy was delivered within 24 hours of surgical excision. Several dose schedules were used, varing from 400cGy in 1 daily fraction to 1900cGy in 4 daily fractions. The average total dose was 1059cGy, and the average dose per fraction was 433cGy. All patients were followed up from 24 to 114 months with a median follow up of 49 months. Results : The overall recurrence rate was $12.6\%$ (21/167) The overall 1-year and 2-year recurrence rates were $10.2\%\;and\;11.4\%$, respectively Among 21 recurrent sites, seventeen sites $(81\%)$ were confirmed within 12 months after surgical excision. Period to recurrence ranged from 1 month to 47 months with a median recurrence time of 9.6 months, The history of previous therapy was only a significant factor in recurrence. Twenty-four patients had history of previous therapy recurrence rates was significantly higher in this group than those without history of Previous therapy $(22.6\%\;vs.\;11.0\%,\;p=0.04)$. There was no serious complication related to radiation therapy. Conclusion : This study suggests that surgical excision followed by radiation therapy is an effective method of preventing keloids and hypertrophic scars.

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돌다리도 두드리며 건너는 자세를!

  • 조홍래
    • KOREAN POULTRY JOURNAL
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    • v.7 no.7 s.69
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    • pp.98-104
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    • 1975
  • 그동안 극심한 불황에 허덕이던 사료업계가 서서히 안정되어 가고 있다는 소식이다. 1$\~$2월의 가수요분 사료를 거의 소비하였고, 사육두수의 증가로 5월에 접어들면서 판매고가 점차 증가하고 있으며 9월 중순경부터 생산판매할 도입사료곡물이 8월말까지 도착된다면 공급에 큰 차질이 없을 것으로 본다. 또 세계적인 풍작으로 수출여력이 증가하여 미국 사료곡물 수출량이 감소추세에 있으며 올해의 미국 옥수수 생산예정량은 60억부셀(1.5억톤)로 현재상태로는 무난히 달성되리라 전망한다. 그러므로 전체적인 추세로 볼 때 수요공급이 원활하여 사료업계의 내일은 매우 밝다. 그러나 안정되어가는 축산업계에 무모한 사육두수의 증식으로 파탄을 자초하는 고질병이 재발하지 않도록 예방을 철저히 하여야 할 것이다.

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Simulation of effect of spray angle on the mixing effect in spray dryer absorber (분무건조 반응기에서 노즐 분사 각도에 따른 혼합효과의 전산 모사)

  • 송호철;김동주;함승주;박진원
    • Proceedings of the Korea Air Pollution Research Association Conference
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    • 2002.04a
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    • pp.305-306
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    • 2002
  • 우리나라 폐기물 발생량은 1991년도까지는 연평균 8%의 증가를 보였으나 1992년 이후부터는 조금씩 감소하는 추세를 나타냈다. 폐기물 발생량의 감소요인은 배출원에서의 원천적인 감량화 노력과 함께 종량제 신시에 따른 쓰레기 분리수거 및 재활용율 제고 등에 따른 것이며, 특히 음식물 쓰레기 및 연탄재발생량의 감소가 크게 나타났다. 그러나 산업활동의 증가로 사업장 폐기물과 건축폐기물은 급증하는 추세를 보이고 있다. (중략)

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모바일 환경을 고려한 효율적인 전자수표시스템

  • 이여진;유성진;정일용
    • Proceedings of the Korean Information Science Society Conference
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    • 2003.04a
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    • pp.374-376
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    • 2003
  • 무선 인터넷 시장의 급속한 성장과 함께 이에 맞는 실용적인 전자지불 방식의 요구가 커지고 있다. 많은 전자지불방식 중에서 전자수표시스템은 계산량이나 정보교환량 측면에서 전자동전방식보다 효율적인 지불수단이다. 그럼에도 불구하고 제한되어 있는 액면가 문제나 지불과정에서 발생하는 거스름의 재사용 문제로 활성화되지 못하고 있다. 이 시스템은 모바일 단말기의 한계에 따른 연산 속도를 고려하였으며, 액면가나 거스름과 같은 문제정올 해결하였다. 부분은닉서명 기법을 이용하여 수표의 액면가의 임의의 표현이 가능하며 거스름의 형태가 처음 발행 받은 수표와 같아 재사용이 가능하게 된다. 이때 거스름으로 재발행 받은 수표는 익명성을 보장하여 어떤 수표의 거스름인지를 알 수 없게 된다.

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Palliative effect of 131I-MIBG in relapsed neuroblastoma after autologous peripheral blood stem cell transplantation (자가 말초혈조혈모세포이식 후 재발된 신경모세포종 3예에서 131I-MIBG의 고식적 치료 효과)

  • Lee, Yong Jik;Hah, Jeong Ok
    • Clinical and Experimental Pediatrics
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    • v.51 no.2
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    • pp.214-218
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    • 2008
  • Neuroblastoma is one of the most common extracranial solid tumor of childhood, and treatment of refractory neuroblastoma remains a significant clinical problem. Iodine-131-metaiodobenzylguanidine ($^{131}I-MIBG$) therapy is an alternative approach to treat stage IV neuroblastoma. We report the palliative effect of $^{131}I-MIBG$ in three cases of relapsed neuroblastoma after autologous peripheral blood stem cell transplantation. $^{131}I-MIBG$ is an effective and relatively nontoxic palliative therapy resulting in reduction of pain and prolongation of survival.

Reconstruction of Distal Radius Using Ultrahigh Molecular Weight Polyethylene Liner after Excision of Giant Cell Tumor - A Case Report - (원위 요골에 발생한 거대 세포종의 일괄 절제 후 초고분자량 폴리에틸렌 삽입물을 이용한 재건술 - 증례보고 -)

  • Jeon, Dae-Geun;Song, Won-Seok;Oh, Jung-Moon
    • The Journal of the Korean bone and joint tumor society
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    • v.10 no.1
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    • pp.29-33
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    • 2004
  • A giant cell tumor (GCT) of the distal radius is not common. Curettage with bone cementation is considered as a treatment of choice but, in the case of recurrence, marked cortical disruption, or articular invasion, en bloc excision and reconstruction with proximal fibular bone graft is usual procedure. In reconstruction of en bloc resected distal radius which had recurred GCT after conservative operation, we used the ultrahigh molecular weight polyethylene (UHMWPE) liner with intramedullary rod and bone cement, because the contamination was extent in previous operation and recurrence after fibular bone graft was fearful. This article introduce our new surgical procedure.

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Postoperative Stability and Occlusal Plane Alternation by Orthognathic Surgery of Skeletal Class III Malocclusion with Anterior Open Bite (전치부 개교를 동반한 골격성 III급 부정교합 환자의 악교정 수술 후 교합평면의 변화와 안정성에 관한 연구)

  • Shin, Soo-Jung;Hwang, Byung-Nam;Lee, Jung-Keun;Rhee, Seung-Hoon
    • The korean journal of orthodontics
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    • v.29 no.1 s.72
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    • pp.113-127
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    • 1999
  • The purpose of this study is to investigate the stability of counterclockwise rotation of mandible by sagittal split ramus osteotomy to correct the skeletal Class III malocclusion with anterior open bite. Twenty five skeletal Class III open bite patients(mean age 20.6 years) who were treated by the sagittal split ramus osteotonues with rigid fixation were examined in this study. Cephalometric radiographs were taken for each Patients Preoperative(T1), ewly Postoperative(T2), and late postoperative Period(T3). Mean postoperative period was 8.0 months. Cephalometric analysis was done and data from T1, T2, and T3 were analyzed statistically by Paired t-test and Pearson correlation analysis. The following results were obtained. 1. Mandibular plane angle decreased $2.9^{\circ}$ and mandibular occlusal plane angle related to SN Plane decreased $2.7^{\circ}$ after orthognathic surgery(T2). At 6 months after orthognathic surgery(T3), mandibular plane angle increased $1.0^{\circ}$, but mandibular occlusal plane angle did not changed. 2. The amount of horizontal relapse long time after orthognathic surgery(T3) was 1.6 mm at B point and it was $22\%$ of the total posterior movements. There was no vertical relapse in the anterior facial height. 3. The related factor with horizontal relapse at late postoperative period was mandibular plane angle(p<0.01). The related factors with decreasing posterior facial height were amount of mandibular setback(p<0.01), increasing of mandibular ramus height(p<0.01), and decrease of the mandibular plane angle during operation(p<0.01). 4. There was no relationship between the amount of changes in mandibular occlusal plan angle during operation and the amount of relapse after surgery.

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Treatment Results and Prognostic Factors in the Management of Locoregional Recurrent Breast Carcinoma (국소재발유암의 치료성적 및 예후 인자)

  • Moon, Sun-Rock;Lee, Hyung-Sik;Kim, Gwi-Eon;Ahn, Ki-Jung;Suh, Chang-Ok;Kyu, John-Juhn;Min, Jin-Sik;Lee, Kyung-Sik;Kim, Byung-Soo;Noh, Jae-Kyung;Koh, Eun-Hee
    • Radiation Oncology Journal
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    • v.8 no.1
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    • pp.65-71
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    • 1990
  • Between January,1974 and December 1980, fifty eight patients with locoregional recurrent breast carcinoma who did not have evidence of distant metastasis after initial treatment of surgery with or without adjuvant chemotherapy were treated with radiation therapy. Among them, five patients were excluded from this study because of incomplete record or incomplete treatment. The 5-year overall survival and disease free survival from the time of locoregional recurrence was $27\%\;and\;15\%$ respectively. In univariate analysis of prognostic variables, the clinical stage at initial diagnosis, recur duration, number of recurrence sites, size of recurrences, response to the treatment, remission duration were all found to have no significant effect on survival or disease free survival. On the other hand, menopausal status at initial diagnosis, number of positive node at initial surgery, whether or not the use of adjuvant chemotherapy after initial mastectomy had definite prognositc significance. In multivariate analysis of prognostic variables, remission duration, menopausal status at diagnosis, number of axillary node at mastectomy had definite prognostic significance. On the other hand, remission duration more than 12 months, premenopaus at initial mastectomy, less than four positive axillary lymph nodes at mastectomy predicted a good prognosis.

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Radiation Therapy Alone for Early Stage Non-small Cell Carcinoma of the Lung (초기 비소세포폐암의 방사선 단독치료)

  • Chun, Ha-Chung;Lee, Myung-Za
    • Radiation Oncology Journal
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    • v.20 no.4
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    • pp.323-327
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    • 2002
  • Purpose : To evaluate the outcome of early stage non-small cell lung cancer patients who were treated with radiation therapy alone and define the optimal radiotherapeutic regimen for these patients. Materials and Methods : A retrospective review was peformed on patients with sage I or II non-small cell carcinoma of the lung that were treated at our institution between June, 1987 and May, 2000. A total of 21 patients treated definitively with radiation therapy alone were included in this study. The age of the patients ranged from 53 to 81 years with a median of 66 years. All the patients were male. The medical reasons for inoperability were lack of pulmonary reserve, cardiovascular disease, poor performance status, old age, and patient refusal in the decreasing order. Pathological evidence was not adequate to characterize the non-small cell subtype in two patients. Of the remaining 19 patients, 16 had squamous cell carcinoma and 3 had adenocarcinoma. Treatment was given with conventional fractionation, once a day, five times a week. The doses to the primary site ranged from 56 Gy to 59 Gy. No patients were lost to follow-up. Results : The overall survival rates for the entire group at 2, 3 and 5 years were 41, 30 and $21\%$, respectively. The cause specific survivals at 2, 3 and 5 years were 55, 36 and $25\%$, respectively. An intercurrent disease was the cause of death in two patients. The cumulative local failure rate at 5 years was $43\%$. Nine of the 21 patients had treatment failures after the curative radiotherapy was attempted. Local recurrences as the first site of failure were documented in 7 patients. Therefore, local failure alone represented $78\%$ of the total failures. Those patients whose tumor sizes were less than 4 cm had a significantly better 5 year disease free survival than those with tumors greater than 4 cm $(0\%\;vs\;36\%)$. Those patients with a Karnofsky performance status less than 70 did not differ significantly with respect to actuarial survival when compared to those with a status greater than 70 $(25\%\;vs\;26\%,\;p>0.05)$. Conclusion : Radiation therapy 리one is an effective and safe treatment for early stage non-small ceil lung cancer patients who are medically inoperable or refuse surgery. Also we believe that a higher radiation dose to the primary site could improve the local control rate, and ultimately the overall survival rate.