• Journal of Korea Entertainment Industry Association
• /
• v.14 no.8
• /
• pp.237-244
• /
• 2020

Sensory impairment is common following a stroke. Tactile afferent inputs from the plantar foot provide important information to the central nervous system to generate balance. The present study, which recruited 50 stroke patients, aims to determine the relationship between plantar tactile sensory threshold (PTST) and balance in patients with stroke. The PTST was evaluated at two sites (hallux and heel) using Semmes-Weinstein monofilaments. The balance abilities were measured by the degree of weight distribution in quiet standing (QS) and sitting-to-standing position (STS) using a MTD system and Berg balance scale (BBS). The hallux and heel sensory thresholds (ST) in the affected side were higher than the non-affected side (P < 0.05). The degree of weight distribution in the affected side was lower than the non-affected side. QS and STS showed P < 0.05, with BBS score of 36.00 ± 1.53. The hallux ST in the affected side correlated with BBS (r = -0.444, P < 0.05), QS (r = -0.332, P < 0.05), and STS (r = -0.390, P < 0.05), whereas the heel ST in the affected side correlated with BBS (r = -0.467, P < 0.05), QS (r = -0.532, P < 0.05), and STS (r = - 0.516, P < 0.05), suggesting that higher detected PTST might have an influence on the decreasing balance abilities. The study of sensory threshold in patients with stroke will help their rehabilitation and sensory evaluation.

• Journal of Hospice and Palliative Care
• /
• v.16 no.4
• /
• pp.205-215
• /
• 2013

Most terminally ill cancer patients experience various physical and psychological symptoms during their illness. In addition to pain, they commonly suffer from fatigue, anorexia-cachexia syndrome, nausea, vomiting and dyspnea. In this paper, I reviewed some of the common non-pain symptoms in terminally ill cancer patients, based on the National Comprehensive Cancer Network (NCCN) guidelines to better understand and treat cancer patients. Cancer-related fatigue (CRF) is a common symptom in terminally ill cancer patients. There are reversible causes of fatigue, which include anemia, sleep disturbance, malnutrition, pain, depression and anxiety, medical comorbidities, hyperthyroidism and hypogonadism. Energy conservation and education are recommended as central management for CRF. Corticosteroid and psychostimulants can be used as well. The anorexia and cachexia syndrome has reversible causes and should be managed. It includes stomatitis, constipation and uncontrolled severe symptoms such as pain or dyspnea, delirium, nausea/vomiting, depression and gastroparesis. To manage the syndrome, it is important to provide emotional support and inform the patient and family of the natural history of the disease. Megesteol acetate, dronabinol and corticosteroid can be helpful. Nausea and vomiting will occur by potentially reversible causes including drug consumption, uremia, infection, anxiety, constipation, gastric irritation and proximal gastrointestinal obstruction. Metoclopramide, haloperidol, olanzapine and ondansetron can be used to manage nausea and vomiting. Dyspnea is common even in terminally ill cancer patients without lung disease. Opioids are effective for symptomatic management of dyspnea. To improve the quality of life for terminally ill cancer patients, we should try to ameliorate these symptoms by paying more attention to patients and understanding of management principles.

• The Korean Journal of Nuclear Medicine
• /
• v.37 no.4
• /
• pp.254-259
• /
• 2003

$^{99m}Tc-galactosyl$ human serum albumin (Tc-GSA) is a radiopharmaceutical that binds to asialoglycoprotein receptors, which are specifically present in the hepatocyte membrane. Because these receptors are decreased in hepatic parenchymal damage, the degree of Tc-GSA accumulation in the liver correlates with findings of liver function test. Hepatic images were performed with Tc-GSA in patients with acute hepatic dysfunction by Amantia Subjunquillea poisoning, and compared with these of liver ultrasonography (USG). Tc-GSA (185 MBq, 3 mg of GSA) was injected intravenously, and dynamic images were recorded for 30 minutes. Time-activity curves for the heart and liver were generated from regions of interest for the whole liver and precordium. Degree of hepatic uptake and clearance rate of Tc-GSA were generated by visual interpretation and semiquantitative analysis parameters (receptor index : LHL15 and index of blood clearance : HH15). Visual assessment of GSA scintigraphy revealed mildly decreased liver uptake in all of subjects. The mean LHL15 and HH15 were 0.886 and 0.621, graded as mild dysfunction in 2, and mild to moderate dysfunction in 1 subject. In contrast, liver USG showed no remarkable changes of hepatic parenchyme. Tc-GSA scintigraphy was considered as a useful imaging modality in the assessment of the hepatic dysfunction.

• The Journal of Korean Academy of Prosthodontics
• /
• v.48 no.3
• /
• pp.215-223
• /
• 2010

Purpose: The present study was aimed to evaluate the level of cortical bone strain during the placement of an implant. The primary concern was to investigate if the extent of overloading area near the marginal bone could be affected by microthread fabricated at the cervical 1/3 of an implant. Materials and methods: Three dimensional finite element analysis was used to simulate the insertion of 3 implants. Control model was $4.1{\times}10$ mm implant (Submerged model, Dentis Co,, Daegu, Korea) equipped with a main thread only. Type I was with main thread and microthread, and Type II had similar thread pattern but was of tapered body. A PC-based finite element software (DEFORM 3D ver 5, SFTC, Columbus, OH, USA) was used to calculate a total of 3,600 steps of analysis, which simulated the whole insertion. Results: Results showed that the strain field in the marginal bone within 1 mm of the implant wall was higher than 4,000 micro-strain in the control model. The size of bone overloading was 1-1.5 mm in Type I, and greater than 2 mm in Type II implants. Conclusion: These results indicate that the marginal bone may be at the risk of resorption on receiving the implant for all 3 implant models studied. Yet, the risk was greater for Type I and Type II implants, which had microthread at the cervical 1/3.

• Food Science of Animal Resources
• /
• v.28 no.5
• /
• pp.521-528
• /
• 2008

This study was performed to evaluate the quality change of pork patties containing silkworm powder and vegetable worm (Paecilomycis japonica) stored for 9 days at $5^{\circ}C$. pH values were higher in treatment groups than that in controls by storage day 6. L (lightness) and a (redness) value were decreased with increasing addition of silkworm powder and vegetable worm powder in pork patties (p<0.05). However, b value (yellowness) was increased with increasing addition amounts of the silkworm powder and the vegetable worm powder (p<0.05). Water holding capacity (WHC) of pork patties was not affected by the silkworm powder and the vegetable worm powder, while pork patties containing 0.4% silkworm powder (T2) showed low cooking loss (p<0.05). Pork patties containing either silkworm powder and vegetable worm alone or a combination of them showed lower lipid oxidation value than that of control (p<0.05). Sensory preference of pork patties was decreased with increased of storage days. The overall acceptance was higher in treatment groups than at control groups at the initial day (p<0.05), yet no significant difference was found during storage. From these results, 0.4% silkworm powder decreased not only cooking loss but also lipid oxidation of pork patties. Also, no adverse effect was found in water holding capacity (WHC) and sensory preference of pork patties. Therefore, the silkworm powder and the vegetable worm powder could be useful to pork meat product industry as additives.

• Journal of Korean Society of Environmental Engineers
• /
• v.39 no.11
• /
• pp.607-612
• /
• 2017

The effect of carbonic anhydrase on $CO_2$ absorption rates and the heat of reaction were evaluated in various amine solutions for post combustion $CO_2$ capture process. The $CO_2$ absorption rate was analyzed in 30 wt% MEA, AMP, DMEA, MDEA aqueous solutions with and without carbonic anhydrase (250 mg/L) from bovine erythrocyte. $CO_2$ absorption rates were increased in all solutions with carbonic anhydrase. The effect of carbonic anhydrase on absorption rates was more in tertiary amine (DMEA and MDEA) solutions than in primary amine (MEA) and hindered amine (AMP) solutions. The heat of reaction of MEA, DMEA, MDEA aqueous solutions with and without carbonic anhydrase were measured using reaction calorimeter. Carbonic anhydrase decreased the heat of absorption in all solutions. The results suggested that tertiary amines that have the excellent desorption ability were suitable for applying carbonic anhydrase to the post combustion $CO_2$ capture process and the effect of carbonic anhydrase was best in MDEA solution.

• Korean Journal of Social Welfare Studies
• /
• v.44 no.3
• /
• pp.207-236
• /
• 2013

This article aims to understand the process of effective leadership in the Community Care Centers for the Disabled(CCCD). Using a qualitative approach and the concept of 'Sensemaking', a term introduced by Weick (1995), I described and explored the process of leadership. Sensemaking enables leaders to have a better grasp of what is going on in their environments. Sensemaking theory offers a perspective on leadership that resolves successfully complex situations surrounding the CCCD. The CCCDs face the environmental changes such as a paradigm shift of disability and a rivalry system with private services. In this time of uncertain change, the CCCDs are in need of leadership of the executives who could reduce complexity with shared meaning. Data were collected over 5 weeks from the 6 CCCDs, through semi-structured interviews, with practitioners, middle managers and chief executives. The interview scripts were thematically analyzed through Atlas-ti programme. The findings showed three subjects, the people's perception of environment, organizational visioning and interactions among post positions. Even though the 6 CCCDs were under the same environment, the perceptions and the enactments of the practitioners were influenced by the chief executives' sensemaking. The important factors of the chief executives' sensemaking were the daily interaction as well as ongoing reflection on their experiences.

• Korean Journal of Food Science and Technology
• /
• v.53 no.6
• /
• pp.715-721
• /
• 2021

Cognitive impairment and Alzheimer's disease are serious social problems associated with the rising elderly population in Korea. 1,2,3,4,6-Penta-O-galloyl-β-ᴅ-glucopyranose (PGG) is a gallotannin isolated from medicinal plants such as Rhus chinensis. This study was performed to evaluate the effect of PGG on biomarkers related to cognitive function in human neuroblastoma SK-N-SH cells. Inhibition of acetylcholinesterase (AChE) activity is considered to be one of the main therapeutic strategies. PGG inhibited AChE activity in the test tube as well as in SK-N-SH cells. In addition, PGG induced protein and mRNA expression of brain-derived neurotrophic factor (BDNF), which is a mammalian neurotrophin that plays major roles in the development, maintenance, repair, and survival of neuronal populations. As one of the underlying molecular mechanisms that induce BDNF expression, PGG induced the activation of Ca²⁺/calmodulin (CaM)-dependent protein kinase II (CaMKII)-cAMP response element binding protein (CREB) pathway. In conclusion, PGG may be an useful material for improving cognitive function.

• Journal of the Korea Society of Computer and Information
• /
• v.27 no.7
• /
• pp.145-152
• /
• 2022

Stroke results in balance disorders, these directly affect autonomy and gait ability. The aim of this meta-analysis was to determine the efficacy of proprioceptive neuromuscular facilitation on balance and gait. We included all randomized controlled trials assessing the efficacy of proprioceptive neuromuscular facilitation on balance and gait control in patients after stroke. This study was conducted according to the PRISMA guideline. Cochrane library, CINAHL, and PubMed were searched for studies published up to November 2021, and all randomized controlled trails(RCT) assessing PNF therapy were included. This analysis included only RCT. A total of 18 studies were selected from 1091 records obtained from the databases. The meta-analysis was performed using the R project for statistical computing version 4.0.2. The overall intervention effect was middle (standardized mean difference (SMD): 0.56) Additionally, berg balance scale (SMD: 0.48), functional reach test (SMD: 0.51), timed up and go test (SMD: 0.78), 10m walking test (SMD: 0.52), and dynamic gait index (SMD: 0.33) had medium effect sizes. The average Pedro scale was 6.63 out of 18, with a low risk of bias. These findings indicate that PNF is an effective therapy for improving balance gait in stroke patients.

• 한국체육학회지인문사회과학편
• /
• v.51 no.2
• /
• pp.431-440
• /
• 2012

The purpose of this study was to positively examine whether people with physical disabilities participation behavior model of sport for all applying the theory of planned behavior was appropriate for explaining the participation behavior of sport for all and to investigate the effects of causality within the variables. For this study, a questionnaire was designed base on the contents of measuring total five sub variables drawn from Lee Hyun Su's(2011) via an expert conference. Through validity and reliability verification, the final questionnaire was developed. For data analysis, used PASW statistics 18.0, this study conducted Cronbach's α analysis and exploratory analysis to verify the questionnaire's validity and reliability. It also used SEM and CFA as well utilizing AMOS Ver. 7.0. The results of this study were shown below. First, according to the result of verifying the appropriateness of this study model, the model for this study was found to be appropriate since its evaluation indexes for the appropriateness of a model, such as Normed χ², RMR, IFI, TLI, CFI, and RMSEA, satisfied the criteria for acceptance. Second, there was significantly positive (+) effect of behavioral attitudes on behavioral intention, subjective norms on behavioral intention, perceived behavioral control on behavioral intention, behavioral intention on actual behavior, and perceived behavioral control on actual behavior.