• Title/Summary/Keyword: 장기적 사용성

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Assessment of Radiation Dose for Surrounding Organs and Persons Approaching Patients upon Brachytherapy of Cervical Cancer with $^{192}Ir$ ($^{192}Ir$를 사용한 자궁경부암 치료시 주변 장기 및 근접한 사람의 선량 평가)

  • Kang, Se-Sik
    • Journal of radiological science and technology
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    • v.33 no.3
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    • pp.283-288
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    • 2010
  • In order to evaluate radiation dose on the uterus and surrounding organs during brachytherapy for cervical cancer, of which the frequency of occurrence is high in Korean women, as well as radiation dose on medical staffs in proximity of patients receiving the therapy, a mathematical phantom based on reference Korean was established and the radiation dose was calculated accordingly. For simulation, $^{192}Ir$, which is useful in brachytherapy, was selected as radionuclide. Also, it was presumed that the intensity of initial radiation was 1 Ci. The result indicated the radiation of 4.92E-14 Gy/Ci in the uterus, the source organ. In addition, radiation on people around patient receiving the therapy was found to be 1.24E-07 Sv at a distance of 30 cm.

Compatibility of MODIS Vegetation Indices and Their Sensitivity to Sensor Geometry (MODIS 식생지수에 미치는 센서 geometry의 영향과 센서 간 자료 호환성 검토)

  • Park, Sunyurp
    • Journal of the Korean Geographical Society
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    • v.49 no.1
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    • pp.45-56
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    • 2014
  • Data composite methods have been typically applied to satellite-based vegetation index(VI) data to continuously acquire vegetation greenness over the land surface. Data composites are useful for construction of long-term archives of vegetation indices by minimizing missing data or contamination from noise. In addition, if multi-sensor vegetation indices that are acquired during the same composite periods are used interchangeably, data stability and continuity may be significantly enhanced. This study evaluated the influences of sensor geometry on MODIS vegetation indices and investigated data compatibility of two difference vegetation indices, the Normalized Difference Vegetation Index(NDVI) and the Enhanced Vegetation Index(EVI), for potential improvement of long-term data construction. Relationships between NDVI and EVI turned out statistically significant with variations among vegetation covers. Due to their curvilinear relationships, NDVI became saturated and leveled off as EVI reached high ranges. Correlation coefficients between Terra- and Aqua-based vegetation indices ranged from 0.747 to 0.963 for EVI, and from 0.641 to 0.880 for NDVI, showing better compatibility for EVI compared to NDVI. In-depth analyses of VI outliers that deviated from regression equations constructed from the two different sensors remain as a future study to improve their compatibility.

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A Study on the Judgement Rating for Level of Need for Long-term Care Insurance Using a Decision Tree (노인 장기요양보험의 등급판정을 위한 의사결정나무 연구)

  • Han, Sang-Tae;Kang, Hyun-Cheol;Choi, Bo-Seung;Lee, Seong-Keon
    • Communications for Statistical Applications and Methods
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    • v.18 no.1
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    • pp.137-146
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    • 2011
  • Long-term care insurance is a social insurance system that provides benefits to the elderly who have difficulty taking care of themselves for a period of at least 6 months. This system was started in July, 2008 and it is very important to set proper judgement ratings for the approval process. We try to develop and improve the judgement rating system using decision tree models. Our tree model is found to be more stable and efficient than the previous one.

수컷 흰쥐 생식기관에서의 5-HT 수용체 아형의 유전자 발현과 조절

  • Lee, Jong-Hwa;Lee, Gyeong-Yeop;Jeon, Yun;Lee, Seong-Ho
    • Proceedings of the Korean Society of Developmental Biology Conference
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    • 2003.10a
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    • pp.65-65
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    • 2003
  • Serotonin(5-hydroxytriptamine, 5-HT)은 biogenic amlne류 신경전달물질로써, 다양한 생리조절활성을 갖고있다. 생식과 관련된 5-HT 기능으로 최근 사정 기능의 조절 가능성이 제시되었는데, 항우울제로 흔히 사용되는 selective serotonin reuptake inhibitor(SSRI) 계 약물을 장기 투여할 때 Premature ejaculation이 개선된다는 임상적인 증거들이 보고되었다. 본 연구는 수컷 흰쥐를 사용하여 생식기관, 특히 사정과 관계되는 기관들에서의 5-HT 수용체 아형들의 유전자 발현 여부와 그 조절 기작을 조사하였다. 흰쥐 수컷의 생식장기들인 고환, 부정소, 정관, 정낭에서 사정현상에 관여하리라 추정되는 세로토닌 수용체 아형들(type 1A, 1B, 2C)의 유전자 발현을 RT-PCR과 Southern blot으로 확인하였다. SSRI(sertraline)을 흰쥐에 매일 투여하는 모델(25mg/개체, 2주간)에서 1A 아형의 발현의 경우 정낭에서는 감소하였으나 정관에서는 증가하였고, 1B 아형의 발현은 두 장기에서 공히 증가하였다. 고환 제거후 testosterone(T) 보충 실험 모델을 사용한 실험에서, 정낭에서의 1A와 1B 발현은 T 보충에 의해 감소하였고, 정관에서는 큰 변화가 없었다. 한편 고환, 정낭과 정관에서의 세로토닌 수용체 아형 1A와 1B의 발현은 사춘기의 개시와 함께 증가하였다가 이후 점차 감소하는 경향을 보였다. 본 연구 결과는 사정 현상에 있어서 말초성 세로토닌 시스템이 중요한 역할을 담당할 가능성을 시사하는 것으로써, (i) 고등 포유동물에서의 사정 기작의 조절에 대한 과학적인 이해를 증진시키고, (ⅱ) 세로토닌 수용체 아형간의 특이한 발현과 작용에 대한 이해를 통해 보다 효과적인 사정 부전 치료법 개발을 시도할 수있고, (ⅲ) ontogeny와 sex steroid 의존성에 관련된 연구 시도는 노화와 관련된 사정능력의 변화와 같은 남성과학 분야로의 접목을 기할 수 있다고 사료된다.

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Sulphate Effects on Lime and Chemical Additives Stabilized Soils (생석회와 화학 첨가제 혼합토에 대한 황산염의 영향)

  • 민덕기;황광모;정진형
    • Journal of the Korean Geotechnical Society
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    • v.19 no.6
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    • pp.31-38
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    • 2003
  • It has been recently reported that the presence of sulphate causes abnormal volume changes in lime-stabilized soils. Volume changes in lime-stabilized soils can take place due to sulphate compounds such as ettringite. Sulphate compounds caused a variety of serious geotechnical hazards such as swelling pressure and damages to light structures and pavements. This paper discusses the influence of sulphate on the soil specimens treated with quicklime and chemical additives. The physical and mechanical characteristics were studied by means of laboratory tests. The results showed that the presence of sulphate treated soil reduced the shear strength of the lime treated soils and increased the swelling properties. SEM and XRD results indicated that the presence of sulphate producted needle-like crystals such as ettringite. Moreover, the role of needle-like crystals in specimen was probably related to the swelling properties.

Long-term outcomes of infantile spasms (영아 연축 환아의 장기적 예후에 관한 고찰)

  • Oh, Seak Hee;Lee, Eun-Hye;Joung, Min-Hee;Yum, Mi-Sun;Ko, Tae-Sung
    • Clinical and Experimental Pediatrics
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    • v.53 no.1
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    • pp.80-84
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    • 2010
  • Purpose : The aims of this study were to investigate the long-term outcomes in children with infantile spasms (IS) and to identify the prognostic factors influencing their neurodevelopment. Methods : We retrospectively evaluated seventy two children over five years old who were treated for IS at Asan Medical Center, Seoul, Korea, between 1994 and 2007. Forty-three children were contacted by telephone or medical follow-up to assess their current neurodevelopmental status. Multiple logistic regression was used to calculate odds ratios (ORs) and 95% confidence interval (95% CIs) of risk factors for unfavorable outcomes.Results : The mean follow-up duration for these 43 children was $7.2{\pm}1.5$ years (range, 4.5 to 13.0 years). Of these, 13 (30.2%) had cryptogenic and 30 (69.8%) had symptomatic IS. Eleven (25.6%) children were initially treated with adrenocorticotrophic hormone (ACTH) therapy, with a mean treatment lag of $1.3{\pm}1.9$ months (range; 0.1 to 7.0 months). Eighteen (41.8%) children clinically responded to initial treatment, as shown by EEG response. Overall, 22 (51.2%) children had at least moderate neurodevelopmental disorders and 2 (4.8%) died. In univariate analysis, etiology (symptomatic) and poor electroclinical response to initial treatment were related to long-term unfavorable outcomes. In multivariate analysis, response to primary treatment was the sole significant independent risk factor with a high OR. Conclusion : Overall prognosis of children with IS was poor. Electroclinical non-responsiveness to initial treatment was related to unfavorable long-term outcomes, indicating that initial control of seizures may be important in reducing the likelihood of poor neurodevelopment.

Estimation of the Characteristics of Delayed Failure and Long-term Strength of Granite by Brazilian Disc Test (압열인장시험을 이용한 화강암의 지연파괴특성 및 장기안정성 평가)

  • Jung, Yong-Bok;Cheon, Dae-Sung;Park, Eui-Seob;Park, Chan;Lee, Yun-Su;Park, Chul-Whan;Choi, Byung-Hee
    • Tunnel and Underground Space
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    • v.24 no.1
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    • pp.67-80
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    • 2014
  • Long-term stability and delayed failure of granite were evaluated through the laboratory test based on Wilkins method and Brazilian disc test (BDT) which yields tensile strength, mode I fracture toughness and subcritical crack growth parameters. Then, the long-term strength of granite was estimated by using analytical models and long-term stability of compressed air-energy storage (CAES) pilot cavern pressurized up to 5 ~ 6 MPa was evaluated using numerical code, FRACOD with the determined subcritical crack growth parameters. The results of test and analyses showed that the subcritical crack growth index, n was determined as 29.39 and the inner pressure of 5 ~ 6 MPa had an insignificant effect on the long-term stability of pilot cavern. It was also found that the measurement and analysis of acoustic emission events can describe the accumulation of damage due to subcritical crack growth quantitatively. That is, AE monitoring can provide the current status of rock under loading if we make an identical installation condition in the field with that of the laboratory test.

CIGS 박막 반응메카니즘 및 생성공정의 이해

  • Kim, U-Gyeong
    • Proceedings of the Korean Vacuum Society Conference
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    • 2010.02a
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    • pp.24-24
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    • 2010
  • Chalcopyrite $Cu(In,Ga)Se_2$ (CIGS) 화합물 반도체는 고효율 박막태양전지의 광 흡수층으로 사용되는 물질 중 가장 우수한 효율 (19.9%, NREL 2008)을 보유하고 있다. CIGS는 직접천이형 에너지밴드갭 (direct bandgap)을 가지고 있고, 광흡수계수가 $1{\times}10^5\;cm^{-1}$로서 반도체 중 서 가장 흡수율이 높은 재료에 속하여 두께 $1{\sim}2\;{\mu}m$의 박막으로도 고효율의 태양전지 제조가 가능하고, 또한 장기적으로 전기광학적 안정성이 매우 우수한 특성을 지니고 있다. 현재 고효율 CIGS 셀생성을 위해 널리 사용되고 있는 CIGS 흡수층 성장공정은 "co-evaporation(동시증발법)"과 2-step 공정이라 불리는 "sputter-selenization(스퍼터-셀렌화)" 방법이다. 동시증발법은 개별원소 Cu, In, Ga, Se 들을 고진공 분위기에서 고온 ($550{\sim}600^{\circ}C$)기판위에 증착하는 방법으로 소면적에서 가장 좋은 효율(~20%)을 보이는 공정이다. 하지만, 고온, 고진공 공정조건과 대면적 증착시 온도 및 조성 불균일 등의 문제점 등으로 상용화에 어려움이 있다. 스퍼터-셀렌화 공정은 1단계에서 스퍼터링 방식으로 CuGaIn 전구체를 증착하고, 2단계에서 고온($550{\sim}600^{\circ}C$)하에 $H_2Se$ 혹은 Se vapor와 반응시켜 CIGS를 생성한다. 일본의 Showa Shell와 Honda Soltec 등에 의해 이미 상업화 되었듯이, 저비용 대면적으로 상업화 가능성이 높은 공정으로 평가되고 있다. 하지만, 2단계에서 사용되는 $H_2Se$ 및 Se vapor의 유독성, 기상 Se과 금속전구체 간의 느린 셀렌화 반응속도, 셀렌화반응 후 생성된 CIGS 박막 두께방향으로의 Ga 불균일분포, 생성된 CIGS/Mo 계면 접착력 저하등의 문제점들이 해결되어야만 상업화에 성공할 수 있을 것이다. 본 Tutorial에서는 CIGS 물질의 열역학 상평형과 반응메카니즘에 대해 설명하고, 다양한 생성 공정들을 소개할 것이다.

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Permeation and diffusion of gases through polytetrafluoroethylene membrane (Polytetrafluoroethylene막을 통한 기체의 투과 및 확산)

  • 김형민;김남인;이우태
    • Proceedings of the Membrane Society of Korea Conference
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    • 1994.10a
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    • pp.34-35
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    • 1994
  • 기체혼합물의 분리및 정제기술은 에너지 절약의 관점과 새로운 기능성 고분자의 개발로 고분자막에 의한 분리법이 관심을 끌게되었다. 공기로부터 산소부화, 방사성 크세논 및 크립론의 제거, 제련소 폐가스증의 수소분리, 천연가스로부터 헬륨의 회수분야등은 실제로 산업적으로 실용화되고 있다. 그러나 고분자막은 일반적으로 투과성과 선택성이 서로 상반되는 경향을 나타내므로, 투과성과 분리성이 좋은 기능성 고분자막의 개발에 다양한 연구가 필요로 하고있다. 본 연구에서 사용한 PTFE(polytetrafluoroethylene)는 결정성 고분자로서 넓은 온도범위에서 낮은 마찰계수, 우수한 전기적 절연특성, 강한 Carbon-fluorine 겹합에 기인한 높은 열적 안정성, 화확적 불활성때문에 공업용 고분자 재료로서 독특한 위치를 차지하고 있다. 최근에 미국과 일본을 주축으로 상용화딘 공기전지(Zinc-air battery)는 PTFE막의 뛰어난 소수성과 화학적 저항성으로 수은 전지의 대체품으로 주목받고 있는데, 장기 방전시 성능 저하가 따르므로 막을 통한 산소투과성을 방전에 필요한 최소값으로 감소시키는 것이 중요한 과제가 되고있다.

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Research On Development of Usability Evaluation Contents and Weight of Importance for the Fire Detector Product (화재감지기 제품디자인 사용성 평가항목 개발 및 이해관계자 가중치평가 연구)

  • Jung, Ji-Yoon;Lee, Sang-Ki;Kim, Ji-Hyang;Yun, Su-Ji;Jang, Gi-Yong;Lee, Sung-Pil
    • The Journal of the Korea Contents Association
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    • v.19 no.1
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    • pp.404-412
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    • 2019
  • The purpose of this study is to develop the usability evaluation contents based on the needs of different stakeholder's related to the usability of the product, and to derive the design direction and apply it as the evaluation standard by applying the product design based on the results. I created a stakeholder map for a fire detector product and identified stakeholders related to usability. Based on 3 factors(Physical, cognitive, emotional) of the usability evaluation, I conducted survey on the building users and the building managers who have different requirements. There are 12 directions (ease of installation, durability, maintainability, additional functionality, effectiveness, attractiveness, visibility, consistency of information, environmental harmony, consistency, Image suitability, reliability). Through weighted analysis of three usability evaluation factors, I found factors were ranked in the same order of importance, but they were different in importance figure. Based on the results of the survey, overall product usability aspects were improved but effectiveness and environmental coordination aspects needed to be improved.