• Journal of the Korean Society of Radiology
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• v.82 no.3
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• pp.654-669
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• 2021

Purpose To evaluate the accuracy of MRI in predicting the pathological complete response (pCR) and the residual tumor size of breast cancer after neoadjucant chemotherapy (NAC), and to determine the factors affecting the accuarcy. Materials and Methods Eighty-eight breast cancer patients who underwent surgery after NAC at our center between 2010 and 2017 were included in this study. pCR was defined as the absence of invasive cancer on pathological evaluation. The maximum diameter of the residual tumor on post-NAC MRI was compared with the tumor size of the surgical specimen measured pathologically. Statistical analysis was performed to elucidate the factors affecting pCR and the residual tumor size-discrepancy between the MRI and the pathological measurements. Results The pCR rate was 10%. The diagnostic accuracy of MRI and the area under the curve for predicting pCR were 90.91% and 0.8017, respectively. The residual tumor sizes obtained using MRI and pathological measurements showed a strong correlation (r = 0.9, p < 0.001), especially in patients with a single mass lesion (p = 0.047). The size discrepancy between MRI and the pathological measurements was significantly greater in patients with the luminal type (p = 0.023) and multifocal tumors/non-mass enhancement on pre-NAC MRI (p = 0.047). Conclusion MRI is an accurate tool for evaluating pCR and residual tumor size in breast cancer patients who receive NAC. Tumor subtype and initial MRI features affect the accuracy of MRI.

• The Journal of the Petrological Society of Korea
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• v.9 no.3
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• pp.142-168
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• 2000

The granites distributed in the Kyongsang basin contain the rocks which are different from the host rocks, and they are known as magic microgranular enclaves. The genesis of the magic micro-granular enclaves can be divided into four types: (1) rock fragments from country rocks; (2) cumulation of the early crystals in host magma or disruption of early chilled borders; (3) magma mingling; and (4) restite. These enclaves can be easily found in the granites around Mt. Wonhyo, Yangsan city. They are ellipsoidal in shape, and have phenocrysts might be originated from the host rocks and sharp contacts with the granites. Under the microscope, textures such as oscillation zoning, horn-blende-mantled quartz, rapakivi texture, and acicular apatite are observed, and these indicate that the enclaves were originated from magma and then produced by chilling. The evidences showing that the enclaves were formed by magma mingling are: (1) petrographical characteristics; (2) similarity of the compositions between the rim of plagioclase in the enclave and plagioclase in the granite; (3) linear trends of the major elements; (4) total REE content of the enclaves; and (5) Textural and compositional variations from rim to core in zoned enclaves. The magic end member of the enclave is regarded as the aphyric basaltic andesite in Mt. Sinbul-Youngchui area. The granites around Mt. Wonhyo experienced the magma mingling process which was produced by the injection of mafic magma at about 70 Ma, during the crystal differentiation, and then continued the crystallization. The equigranular granites and the micrographic granites in the study area are considered as the results after the magma mingling process.

• Journal of Welding and Joining
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• v.17 no.2
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• pp.25-28
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• 1999

국내에 건설되어 거의 20∼30년 가동되고 있는 발전설비, 석유화학 플랜트 등 거대설비 기기의 건전성(integrity) 및 신뢰성 확보와 잔존수명 예측을 위해서는 구조물 내부 또는 표층부에 존재하는 결 함의 특성을 아는 것과 함께 그 재료의 특정 부위에 어느정도의 응력이나 변형이 있는가를 아는 것이 매우 중요하다. 일반적으로 강 용접부의 비파괴적 결함검출에는 주로 SV파(vertically shear wave)와 SH파(horizontally shear wave)라 불리는 횡파를 이용한 초음파사각탐상법이 실용화되어 이용되고 있다. 그러나 비파괴적인 방법에 의한 실험적인 잔류응력 측정, 변형해석법에는 전기 저항 및 자기 스트레인 게이지법, X선회절법, 광탄성법(photoelasticity), 모아레(Mohr's)법, 레이저스펙클(Laser speackle)법, 응 력도료법, Barkhausen Nosise법, Caustics법 등이 제시되어 있으나 그 유용성 면에서는 아직 해결되야할 문제가 많이 남아 있는 실정이다. 응력이나 변형을 해석하는 방법으로 이론적 방법, 계산적 방법 실험적 방법이 잇다. 이론적 방법에는 재료 역학적으로 취급하는 방법, 탄성론 등이 있고, 계산적인 방법에는 유한요소법이 있지만, 이론적 방법이나 계산적 방법만으로는 해석이 불가능한 경우가 많기 때문에 실험 적 방법이 필요하게 된다. 이 글에서는 파괴 시험 또는 다른 비파괴평가기술에 비해 간편한 측정, 높은 측정정도, 시험결과 도출의 신속성, 검사비용의 절감 등 많은 장점을 가지고 있고 실험적으로 유용성이 일부 검증되고 있는 음탄성법(Acoustoelasticity)에 의한 잔류응력 측정법에 관해 소개하고자 한다.TEX> mg/L(평균 49 mg/L)로 비교적 안정적인 처리효율을 보여주었다. 본 연구결과 HVC 공정은 화학약품 사용량의 절감 및 이에 따른 화학슬러지 발생량의 감소를 기대 할 수 있는 친환경기술로 유지관리비를 최소화할 수 있는 장점이 있었다. 않은 사람들 중 미래의 검진실행의지에 건강소식지가 영향을 미친 경우는 48.7%였다. 보건교육을 받은 후 유방암 자가검진 실천율은 사업군에서 53.9%로 받기 전의 27.3%보다 증가하였으나 대조군의 경우는 별 차이가 없었다. 연령별로는 60대가 가장 높았고 사업군에서 검진율의 증가분은 30대가 가장 컸다. 교육수준별로는 사업군은 고졸이, 대조군은 전문대졸이 가장 높았고 사업군에서 검진율의 증가분은 고졸에서 가장 컸다. 보건교육 후 유방암과 관련된 건강지식의 정도는 사업군이 3.7점으로 대조군보다 유의하게 높았으며, 유방암 자가검진법을 실천하는 사람들의 동기는 ‘일반 대중매체의 영향’이 가장 많았으며 건강소식지가 동기인 경우도 20.4%였다. 사업군에서 건강소식지가 유방암 자가검진법 실천에 영향을 미친 경우가 79.6%였으며 유방암 자가검진법에 관한 보건교육을 받고 실천하지 않은 사람들 중 미래의 실천의지에 건강소식지가 영향을 미친 경우는 43.6%였다. 이상의 소견에서 지역주민을 대상으로 인쇄매체를 통한 보건교육은 인쇄물만으로도 쉽게 실천 할 수 있는 유방암 자가검진법이 가장 효과적이었으며, 자궁암검진에 관해서도 검진을 받을 수 있도록 지역사회의 보건의료의 하부구조를 정비하여 제도적 장치를 마련하고 정보를 제공한다면 자궁암검진 실천율도 증가할 것이다.고 12.9% 의 발달율을 보여 유의적인 차이를 보이지 않았다. 이상의 결과로 보아 핵이식 수정란을 효율적으로 생산하기 위하여

• Journal of the Korean Geophysical Society
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• v.3 no.1
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• pp.1-12
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• 2000

A palaeomagnetic study was carried out on Early through Late Cretaceous sandstones and volcanic sequences (the Songnaedong Formation, Chaeyaksan Volcanics, Konchonri Formation, and Jusasan Andesite it ascending order) from Konchonri area in the northern Milyang subbasin of the Kyongsang Basin, Korea. A high-temperature stable remanence with direction of $d=22.9^{\circ},\;i=59.1^{\circ}\;({\alpha}_{95}=3.0^{\circ})$ has been isolated and a corresponding pole was $71.6^{\circ}N,\;199.6^{\circ}E\;(A_{95}=4.2^{\circ})$. The characteristic high-temperature component resides in both hematite and magnetite. The primary nature of this remanence is confirmed from positive fold and reversals tests, The palaeopole is consistent with those of the Hayang Group in other parts of the Kyongsang Basin. A comparison of the palaeomagnetic pole position from the studied area with the contemporary pole from China west of the Tan-Lu fault presents that Konchonri area has experienced little latitudinal displacement nor vertical-axis block rotation relative to the Chinese blocks since the Cretaceous. Based on the formations indicating dual polarity, radiometric and paleontologic data, the magnetostratigraphic age of the studied sequence from the Songnedong Formation to the Jusasan Andesite ranges from upper Albian to lower Campanian reverse polarity chronozone. On the other hand, volcanic samples of the Chaeyaksan Volcanics and the Jusasan Andesite showed the scattered directions considered in group, even though individual sample showed a stable remanent magnetization in response to thermal demagnetization. It indicates that they have been reworked after acquisition of the stable remanent magnetization.

• The Korean Chronic Disease News
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• no.319
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• pp.1-18
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• 2007

복지시대의 첨병-구례군보건의료원 김영락 원장/노인복지시설 통합.개편/비만치료도 건강보험급여 대상/보건소 중심, 만성질환 관리시스템 구축/임의왕진 의료급여비 환수/적절한 운동이 '대장암' 예방한다/모유수유 오래하면 유방암 감소/50대 두통, 어지러움은 중풍 의심/축수산물 항생제 잔류 기준 엄격 적용/담배연기 없는 깨끗한 병원/레이저 이용 암 세포만 선택적 파괴/'주민 삶의 질 적인 개선' 지향-구례구보건의료원/농촌지역 공공보건의료 질적 발전에 정열 쏟아-김영락 원장/동아제약, 유럽 시장 본격진출/LG, 세계 최초 항구토 패치 도입/한미약품, 의약사 금융지원 한다/국내 첫 생약제제 임상시험 지침 마련/암환자 완치율 44.4% 수준/고혈압.당뇨병치료율 2배 증가/혈압 없어도 '코골면' 고혈압 위험 높아/조기위암 전체 위암 절반 넘었다/항암면역세포치료제 NKM 허가/OECD Health Data 2007 보건의료실태분석

• Radiation Oncology Journal
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• v.12 no.3
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• pp.349-359
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• 1994

Purpose: The primary gastrointestinal non-Hodgkin's lymphoma(GI-NHL) is the most common extranodal NHL. Surgery with postoperative radiotherapy or chemotherapy was tried with some success, but proper management guidelines have not been estabilished in localized GI-NHL due to its rarity and the lack of randomized trials. So we designed this study to evaluate treatment results and the lack of randomized trials. So we designed this study to evaluate treatment results and prognostic factors in localized GI-NHL, and to assess proper treatment mdality after surgical resection accordig to risk factors by survival analysis. Method: Seventy three patients who received surgical resection due to localized GI-NHL from Jan. 1916 to Apr. 1991 were reviewed in this study. Prognostic factors were analyzed by multivariate analysis program including postoperative treatment methods, and treatment results were compared according to prognostic factors and treatment modalities. Results: Overall 5-year survival rate was 62.3%, for all patients. The 5-year survival rate was 80.0% for patients with stage I GI-NHL and 45.7% for those with stage II. Chemotherapy or not, stage and residuum or not after surgical resection were significant independent prognositic factors. Postoperative adjuvant treatments showed significant survival benefit. In patients with high risk factors such as stage II or residuum after surgical resection, postoperative combined chemotherapy and radiotherapy showed better survival than those treated with single modality. Conclusions: Chemothrapy or not, stage, and residuum or not were important prognostic factors of patients with localized GI-NHL after surgical resection. Either chemotherapy or radiation therapy alone after surgical resection is recommanded for patients without high risk factors(stage II or residuum after surgical resection) but the postoperative combined chemotherapy and radiotherapy seems to be beneficial for patients with high risk factors.

• Journal of the Korean earth science society
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• v.21 no.3
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• pp.323-336
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• 2000

Ultramafic rocks in Choongnam area are mainly serpenitinites which are parent rock of talc and asbestos ore deposits. About 10 $^{\circ}$ NNE-trending parallel serpentinites masses occur as discontineous isolated lenticular intrusive bodies in Precambrian gneiss complex between Hongseong-Kwangcheon line and Onyang-Cheongyang line. The sizes of serpentinites vary from several centimeters to 1 kilometer in width and from several meters to 5 kilometers in length. The serpentinites show high SiO$_2$(39.99wt.% in average), MgO(38.46wt % in average), Cr(>1011ppm), Ni(>1660ppm), and Co(>80ppm). Most serpentinites contain serpentine more than 50%. Some serpentines contain original minerals such as olivine, pyroxene and chromite. Also, serpentinites body may contain a little serpentinized peridotite, and some talc and asbestos ore deposits. The original rocks of the serpentinites interpreted as Alpine type ultramafic rocks, and dunite and/or harzburgite which were originated from slightly depleted upper mantle(30${\sim}$40km deep), and emplaced in the crust through the large fault zones. It seems that main serpentinization from the original rocks was occurred during greenschist and/or amphibolite facies regional metamorphism in Choongnam area.

• The Journal of the Petrological Society of Korea
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• v.2 no.2
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• pp.130-138
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• 1993

Kyeonggi Gneiss complex forming Korean Precambrian basement is mainly composed of high-grade metasedimentary rocks, which are generally difficult to determine their absolute ages. We examined the feasibility of successive absolute age determination method for the marbles from this basement. We used hydrochloric acid for the selective dissolution of carbonate minerals from the marbles. Trace element analysis shows that most of Zr and Rb are concentrated in the residues. U in the residue is more abundant than that in HC1-dissolved parts. Pb, Sr, Sm, and Nd are somewhat evenly distributed between HC1-dissolved parts and the residues. }Th shows rather complex behavior. Sr isotopic compositions of the HC1-dissolved parts reveal mixing with Sr from non-carbonate minerals having much higher $^{87}Sr/^{86}Sr$ ratios. We suggest that the most reliable method in the age determination for the marbles of this area is measuring Pb isotopic ratios of the pieces of pure marbles.

• Radiation Oncology Journal
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• v.15 no.3
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• pp.251-254
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• 1997

Purpose : Simple hysterectomy is not a standard surgery for invasive cervical carcinoma. This study was performed to investigate the efficacy of radiotherapy following simple hysterectomy in the invasive cervical cancer. Materials and Methods : Retrospective analysis was done for 19 patients with invasive cervical carcinoma who were treated with radiotherapy following simple hysterectomy from April 1989 to December 1993 The median a9e of patients was 47 years old. Patients were treated with external beam radiation therapy alone (17) or external beam radiation therapy plus intra vaginal ovoid irradiation (2). The median follow up period was 46 months. Results : The 4 year overall survival rate was $75\%$. The 4 rear local control rate was $89\%$. Two patients had recurred at the locoregional and distant sites, and another two patients at distant sites. Conclusion : We confirmed that radiotherapy is the adequate treatment modality for patients with invasive cervical cancer who underwent simple hysterectomy.

• 대한핵의학회:학술대회논문집
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• 1997.05a
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• pp.155-155
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• 1997