• Proceedings of the KOSOMBE Conference
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• v.1996 no.11
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• pp.165-168
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• 1996

Though the planar gradient coils, designed by the magnetic energy minimization procedure, have smaller inductance than conventional gradient coils, the planar gradient oils often suffer from their poor magnetic field linearity. Scaling the spatial frequencies of the current density function designed by the magnetic energy minimization procedure, magnetic field linearity of the planar gradient coils can be featly improved with small sacrifice of gradient coil inductance.

• Investigative Magnetic Resonance Imaging
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• v.18 no.1
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• pp.17-24
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• 2014

Purpose : To determine whether high-resolution contrast-enhanced three dimensional imaging with spoiled gradient-recalled sequence (HR-CE 3D-SPGR) plays a meaningful role in the assessment of intracranial vertebral artery (ICVA) and posterior inferior cerebellar artery (PICA) in lateral medullary infarction (LMI). Materials and Methods: Twenty-five patients confirmed with LMI were retrospectively enrolled with approval by the IRB of our institute, and 3T MRI with HR-CE 3D-SPGR and contrast-enhanced magnetic resonance angiography (CE-MRA) were performed. Two radiologists who were blinded to clinical information and other brain MR images including diffusion weighted image independently evaluated arterial lesions in ICVA and PICA. The demographic characteristics, the area of LMI and cerebellar involvement were analyzed and compared between patients with arterial lesion in ICVA only and patients with arterial lesions in both ICVA and PICA on HR-CE 3D-SPGR. Results: Twenty-two of twenty-five LMI patients had arterial lesions in ICVA or PICA on HR-CE 3D SPGR. However twelve arterial lesions in PICA were not shown on CE-MRA. Concurrent cerebellar involvement appeared more in LMI patients with arterial lesion in ICVA and PICA than those with arterial lesion in ICVA alone (p = 0.069). Conclusion: HR-CE 3D-SPGR can help evaluate arterial lesions in ICVA and PICA for LMI patients.

• Journal of the Korean Institute of Telematics and Electronics S
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• v.35S no.5
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• pp.42-47
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• 1998

Bridcage RF coil is one of the most widely used RF coils in MRI. In order to use birdcage RF coils in open MRI systems, an open tructured birdcage RF coil has been investigated. By opening the ring structure of an original birdcage RF coil and driving the coil at two opening ends, the original birdcage RF coil can be modified to an open structured coil. In order to improve magnetic field uniformity of the open birdcage RF coil, driving voltage phases at the two opening ends can be controlled to be in-phase or out-of-phase each other. Operating frequency of the open birdcage RF coil has been theoretically derived, and the theoretical derivation has been verified by experiments.

• Progress in Medical Physics
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• v.20 no.4
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• pp.235-243
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• 2009

The purpose of this experiment is to know the relation of the detection and characterization of liver's diseases as comparison of finding at MR imaging using a Ferucarbotran (SPIO) and Gd-EOB-DTPA (Primovist) agents in diffuse liver disease. A total of 50 patients (25 men and 25 women, mean age: 50 years) with liver diseases were investigated at 3.0T machine (GE, General Electric Medical System, Excite HD) "with 8 Ch body coil for comparison of diseases and contrast's uptake relation, which used the LAVA, MGRE." All images were performed on the same location with before and after Ferucarbotran and Gd-EOB-DTPA administrations (p<0.05). Contrast to noise ratio of Ferucarbotran and Gd-EOB-DTPA in the HCC were $3.08{\pm}0.12$ and $7.00{\pm}0.27$ with MGRE and LAVA pulse sequence, $3.62{\pm}0.13$ and $2.60{\pm}0.23$ in the hyper-plastic nodule, $1.70{\pm}0.09$ and $2.60{\pm}0.23$ in the meta, $2.12{\pm}0.28$ and $5.86{\pm}0.28$ in the FNH, $4.45{\pm}0.28$ and $1.73{\pm}0.02$ in the abscess and ANOVA test was used to evaluate the diagnostic performance of each disease (p<0.05). In conclusions, two techniques were well demonstrated with the relation of the detection and characterization of liver's diseases.

• Investigative Magnetic Resonance Imaging
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• v.11 no.2
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• pp.119-126
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• 2007

MR (magnetic resonance) imaging of the brachial plexus is challenging because of the complex and tangled anatomy of the brachial plexus and the multifariouness of pathologies that can put on it. Improvements in imaging techniques, including the availability of high resolution MR image systems and high channels multidetector computed tomography (CT), have led to more accurate diagnoses and improved serve for treatment planning. For the purpose of imaging and treatment of the brachioplexopathy, it is considerate to divide traumatic and nontraumatic diseases affecting the brachial plexus. MRI is the current gold standard imaging modality for nontraumatic brachial plexopathy. CT myelography is the preferred for the diagnosis of nerve root avulsions affecting the brachial plexus. Other modalities, such as CT, ultrasonography and positron emission tomography, have a limited role in the evaluation of brachial plexus pathology. High-quality, high-resolution MRI remains the main tool for imaging the brachial plexopathy.

• Journal of Veterinary Clinics
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• v.23 no.3
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• pp.337-339
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• 2006

A 4-year-old, spayed female Maltese dog was presented for evaluation of acute onset of generalized tremor, right-sided head tilt, horizontal nystagmus, and mild ataxia with 4-day duration. However, the dog was bright, alert, and responsive. The neurological examinations revealed that bilateral horizontal-, positional nystagmus, and mild ataxia. Menace responses were also absent in both eyes. Typically, moderate generalized intension tremors were noted in four limbs and the head. No abnormalities were found in hemogram, radiography, and magnetic resonance imaging(MRI). Cytologic examination of cerebrospinal fluid(CSF) revealed a mild nonsuppurative inflammation. Thus, steroid responsive tremor syndrome(SRTS) was strongly suspected because of its inflammatory and idiopathic features. The dog excellently responded to immunosuppressive doses of corticosteroid. Therefore, we definitively diagnosed the dog as SRTS based on the exclusion of other causes of the tremor, clinical signs, and response to treatment. This is a first case report of SRTS in our country and we here describe clinical and neurological features in SRTS.

• Investigative Magnetic Resonance Imaging
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• v.18 no.1
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• pp.52-58
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• 2014

Purpose : To establish a pH measurement system for a mouse tumor study using a clinical scanner, to develop the $^1H$ and 31P radio frequency (RF) coil system and to test pH accuracy with phantoms. Materials and Methods: The $^1H$ and the $^{31}P$ surface coils were designed to acquire signals from mouse tumors. Two coils were positioned orthogonally for geometric decoupling. The pH values of various pH phantoms were calculated using the $^1H$ decoupled $^{31}P$ MR spectrum with the Henderson-Hasselbalch equation. The calculated pH value was compared to that of a pH meter. Results: The mutual coil coupling was shown in a standard $S_{12}$. Coil coupling ($S_{12}$) were -73.0 and -62.3 dB respectively. The signal-to-noise ratio (SNR) obtained from the homogeneous phantom $^1H$ image was greater than 300. The high resolution in vivo mice images were acquired using a $^{31}P$-decoupled $^1H$ coil. The pH values calculated from the $^1H$-decoupled $^{31}P$ spectrum correlated well with the values measured by pH meter ($R^2$=0.97). Conclusion: Accurate pH values can be acquired using a $^1H$-decoupled $^{31}P$ RF coil with a clinical scanner. This two-surface coil system could be applied to other nuclear MRS or MRI.

• Investigative Magnetic Resonance Imaging
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• v.8 no.1
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• pp.32-41
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• 2004

Purpose : To measure the NMR relaxation properties of MnPC, to observe the characteristics of liver enhancement patterns on MR images in experimentally implanted rabbit VX2 tumor model, and to estimate the possibility of tissue specific contrast agent for MnPC in comparison with the hepatobiliary agent. Materials and Methods : Phthalocyanine (PC) was chelated with paramagnetic ions, manganese (Mn). 2.01 g (5.2 mmol) of phthalocyanine was mixed with 0.37 g (1.4 nlmol) of Mn chloride at $310^{\circ}C$ for 36 hours and then purified by chromatography ($CHCl_3:\;CH_3OH=98:2$, volume ratio) to obtain 1.04 g $(46\%)$ of MnPC (molecular weight = 2000 daltons). The T1/T2 relaxivity (R1/R2) for MnPC were determined at a 1.5 T (64 MHz) MR spectrometer. VX2 tumor model was experimentally implanted in the liver parenchyma of rabbits. All MR studies were performed on 1.5 T. The human extremity radio frequency coil of a bird cage type was employed. MR images were acquired at 17 to 24 days after VX2 carcinoma implantation.4 mmol/kg MnPC and 0.01 mmol/kg Mn-DPDP were injected via the ear vein of rabbits. T1-weighted images were obtained with spin-echo (TR/TE=516/14 msec) and fast multiplanar spoiled gradient recalled (TR/TE : 80/4 msec, $60^{\circ}$ flip angle) pulse sequence. Fast spin-echo (TR/TE=1200/85 msec) was used to obtain the T2-weighted images. Results : The value of T1/T2 relaxivity (R1/R2) of MnPC was $7.28\;mM^{-1}S^{-1}$ and $55.56\;mM^{-1}S^{-1}$ respectively at 1.5 T (64 MHz). Because the T2 relaxivity of MnPC that bonded strongly, covalently manganese with phthalocyanine was very high, the signal intensity of liver parenchyma was decreased on postcontrast T2-weighted images and we could easily distinguish the VX2 carcinoma within the liver parenchyma. When MnPC was administrated intravenously, the tumor margin delineation was more remarkable than Mn-DPDP-enhanced images. The enhancement of liver parenchyma with MnPC persisted at relatively high levels over at least one hour after injection of the contrast agents. Conclusion : The hepatic uptake and biliary excretion of MnPC, which are similar to Mn-DPDP, suggest that this agent is a new liver-specific agent. Also, MnPC seems to be used as a dual contrast agent (T1 and T2) with high T2 relaxivity. However, it is warranted that MnPC needs further investigation as a potential contrast agent for MR imaging of the liver. That is, further characterizations of MnPC are needed in vivo and in vitro before clinical trials. The diagnostic potential of MnPC will also have to be examined more in the animal models of additional types.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2003.05d
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• pp.33-37
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• 2003

Endovaginal and endorectal receiver only surface coil were designed for MR imaging(MRI) and $^1H$ MR spectroscopy(MRS) for the uterine cervix and the prostate. The shape of endovaginal coil wire was rectangular with round comer. The shape of endorectal coil wire was long elliptic shape during insertion and circular shape after insertion. Conventional spin echo and fast spin echo sequences were used as T1 and T2 weighted imaging sequences, respectively. 3D volume localized in vivo $^1H$ MR spectroscopy of the human cervix and prostate was performed using PRESS or STEAM localization method. Using home-built endvaginal and endorectal coils, excellent T1 and T2 images were obtained to visualize early cervical and prostate tumors. 3D volume localized in vivo $^1H$ MRS was useful to differentiate the cancerous tissue from the normal tissue.

• Journal of Korea Multimedia Society
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• v.19 no.2
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• pp.375-385
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• 2016

Recently, several implantable hearing aids such as cochlear implant, middle ear implant, etc., which have a module receiving power and signal from outside the body, are frequently used to treat the hearing impaired patients. Most of implantable hearing aids are adopted permanent magnet pairs to couple between internal and external devices for the enhancement of power transmission. Generally, the internal device which containing the magnet in the center of receiving coil is implanted under the skin of human temporal bone. In case of MRI scanning of a patient with the implantable hearing aid, however, homogeneous magnetic fields of the MRI might be interfered by the implanted magnet. For the above reasons, the MR image is degraded by large area of artifact, so that diagnostics are almost impossible in deteriorated region. In this paper, we proposed an external coil system that can reduce the artifact of MR image due to the internal coupling magnet. By finite element analysis estimating area of MR artifact according to varying current and shape of the external coil, optimal coil parameters were extracted. Finally, the effectiveness of the proposed external coil system was verified by confirming the artifact at real MRI scan.