• Title/Summary/Keyword: 자극-반응법

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A Study on Aesthetic Response on Symmetric Balance & Asymmetric Balance by Involvement (관여수준에 따른 대칭적 균형과 비대칭적 균형의 심미적 반응에 관한 연구)

  • 이진렬;홍정표;김진아
    • Archives of design research
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    • v.15 no.3
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    • pp.73-82
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    • 2002
  • This research suggests relative perspective against to the existing researches which consider balance as mere one of aesthetic elements that balance could lead different consumer aesthetic response according to product characteristics. From the results of this study, we can suggest that higher level of balance encourage positive consumer aesthetic response in high involvement products and contrary, lower level of balance encourage positive consumer aesthetic response. It's expected for the results of this study to suggest more useful design approach in theoretical and practitional fields. In the future researches, more profound studies with more number of stimuli, more levels of balance distortion and more number of moderating variables should be peformed to withdraw more useful results.

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A Study on the Effectiveness Measurement of TV Home Shopping Advertising Using think aloud and linguistic Analysis (사고발성법과 언어분석을 활용한 TV 홈쇼핑 광고의 효과측정 연구)

  • Ryu, Yeon-Jae
    • Asia-pacific Journal of Multimedia Services Convergent with Art, Humanities, and Sociology
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    • v.9 no.9
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    • pp.797-808
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    • 2019
  • The purpose of this study is to collect the psychological responses that occur while watching TV home shopping ads in verbal form, and explore the possibility of measuring the effectiveness of TV home shopping ads using linguistic analysis. The psychological responses during watching positive and negative ads of participants(40 housewives and female college students) were collected in a linguistic form using a think aloud and self-report measurement. It was analyzed by KLIWC, a Korean language analysis program. As a result of the analysis, there was a difference in psychosocial variables as well as linguistic variables between positive and negative evaluation ads. Also, various variables of KLIWC were correlated with the variables of advertising effectiveness (purchase stimulus, ad attitude, product attitude, purchase intention) and advertising response variables. This suggests the possibility of constructing a psychological response profile and measurement of advertising effectiveness using language analysis.

Response State of EEG Wave Type on Visual Cortex According to Color Vision Target (색각 시표에 따른 시피질 뇌파의 반응 상태)

  • Kim, Douk Hoon
    • Journal of Korean Ophthalmic Optics Society
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    • v.5 no.2
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    • pp.5-9
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    • 2000
  • The visual evoked potential was electrophysiological method for the identify of the EEG response on visual cortex. This test was objective test method on the eye function. This study was used the visual evoked potential for the objective color test. The subjects was a normal color function in Korean adults. The test condition was performed on the differens distance and illumination. According to convergence condition of color vision target. On the appearance of EEG wave of visual stimulation on visual cortex. The most EEG wave style was delta wave, and the next amount wave form was beta wave and theta wave, and the least EEG wave form was alpha wave. The histogram of amplitude of EEG wave form was almost non-Gaussian shape, and the phase diagram of amplitude was almost all linear shape. On the kinds of color vision target, the frequency of EEG wave style appeared a similar results.

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Attentional Bias toward Angry Faces in Typically Developing Children and Children with Autism Spectrum Disorder (정상 발달 아동과 자폐 스펙트럼 장애 아동의 분노 표정에 대한 주의 편향)

  • Yunmin Choi;So-Yeon Kim
    • Science of Emotion and Sensibility
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    • v.27 no.3
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    • pp.121-134
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    • 2024
  • This study aimed to assess the attentional bias toward angry faces in typically developing (TD) children and children with autism spectrum disorder (ASD). A continuous performance task was employed, where a distractor appeared as a target letter ("T") and changed direction every 1,250 ms. Longer reaction times to the target in the presence of a distractor, compared to its absence, were considered as evidence of attentional bias toward the distractor. The task assessed the attentional bias toward angry faces in 14 boys with ASD and 17 TD boys, aged 6-12 years. A repeated-measures analysis of variance was conducted on reaction times with emotion, time, and group as independent variables. The three-way interaction effect approached significance. Group-specific analyses revealed that TD children exhibited significant attentional capture when angry faces first appeared, whereas those with ASD did not. Accuracy analysis revealed no significant differences between the groups, with both groups maintaining >85% accuracy, confirming the task's suitability for school-aged children. The absence of attentional bias toward angry faces in children with ASD indicates that these faces may not be perceived as particularly salient for children with ASD. These findings denote that interventions encouraging top-down processing of emotional cues, such as angry faces, may support the development of adaptive social skills in children with ASD.

GRO-${\alpha}$, IL-8 and ENA-78 : Expressed by Stimulated Endothelial Cells and Increased PMN Adhesion (활성화된 내피세포에서 GRO-${\alpha}$, IL-8 및 ENA-78의 발현양상과 호중구 부착에 미치는 영향)

  • Ryu, Ki-Chan;Kim, Yun-Seong;Kim, Yong-Ki;Kim, In-Ju;Kim, Young-Dae;Lee, Chang-Hun;Park, Do-Youn;Kim, Ji-Yeon;Ha, Tae-Jeong;Lee, Min-Ki;Park, Soon-Kew
    • Tuberculosis and Respiratory Diseases
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    • v.52 no.2
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    • pp.145-155
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    • 2002
  • Background: Inflammation, where vascular endothelial cells are activated by cytokines, recruits circulating leukocytes such as neutrophils into the tissues. Mononuclear phagocytes as well as tissue cells activated by these stimuli produce these chemokines. In this study, thr effects of IL-1 and LPS on the expression of CXC chemokines such as GRO-${\alpha}$, IL-8 and ENA-78 in vascular endothelial cells and the neutrophil adhesion effects of ENA-78 and GRO-${\alpha}$ was investigated. Methods: Human umbilical vein endothelial cells were cultured and stimulated with various concentrations of IL-1 and LPS. The concentrations of the GRO-${\alpha}$, IL-8 and ENA-78 secreted were measured using enzymelinked immunosorbent assay. The effects of ENA-78 and GRO-${\alpha}$ on neutrophil adhesion to the endothelial cells were also investigated. Results: The addition of IL-1 and LPS to the vascular endothelial cells induced GRO-${\alpha}$ IL-8 and ENA-78 secretion in a time- and dose-dependent manner. The neutrophil adhesion was also increased by induction of ENA-78 and GRO-${\alpha}$ to the vascular endothelial cells in a dose-dependent manner. Conclusion: CXC chemokines such as GRO-${\alpha}$, IL-8 and ENA-78 secreted by the vascular endothelial cells play an important role in the acute inflammatory responses by stimulating neutrophil adhesion to the vascular endothelial cells, raising the possibility that the CXC chemokines are one of the targets in the clinical application of acute inflammation.

Analysis of Ammonia Gas Using Ion Chromatography (이온 크로마토그래피에 의한 기체상 암모니아의 분석법 확립)

  • Lee, Jong-Hae;Min, Byung-Hun;Jeon, Ryong;Kim, Jin-Seok;Kim, Yong-Du
    • Proceedings of the Korea Air Pollution Research Association Conference
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    • 2003.11a
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    • pp.366-367
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    • 2003
  • 암모니아 가스는 무색의 기체이지만 자극성이 크면서 부식성이 있고 수용액이 알칼리성인 대표적인 악취물질이다. 보통의 경우는 굴뚝 등에서 배출가스의 형태로 대량 방출되기도 하지만 자연상태에서도 여러 가지 생물학적 또는 화학적 반응 등을 통하여 생성되므로, 일상적인 생활 공간에서도 쉽게 검출될 수 있는 물질이다. 대기 중 암모니아의 농도는 기체상 시료를 직접 분석하는 가스 크로마토그래피와 시료를 액체상으로 변환시킨 후 암모늄 양이온의 농도를 분광광도법이나 중화적정법으로 측정한다. (중략)

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Facial Motor Evoked Potential Techniques and Functional Prediction during Cerebello-pontine Angle Surgery (소뇌교각 수술 중에 안면운동유발전위의 검사방법과 기능적 예측인자)

  • Baek, Jae-Seung;Park, Sang-Ku;Kim, Dong-Jun;Park, Chan-Woo;Lim, Sung-Hyuk;Lee, Jang Ho;Cho, Young-Kuk
    • Korean Journal of Clinical Laboratory Science
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    • v.50 no.4
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    • pp.470-476
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    • 2018
  • Facial motor evoked potential (FMEP) by multi-pulse transcranial electrical stimulation (mpTES) can complement free-running electromyography (EMG) and direct facial nerve stimulation to predict the functional integrity of the facial nerve during cerebello-pontine angle (CPA) tumor surgery. The purpose of this paper is to examine the standardized test methods and the usefulness of FMEP as a predictor of facial nerve function and to minimize the incidence of facial paralysis as an aftereffect of surgery. TES was delivered through electrode Mz (cathode) - M3/M4 (anode), and extracranially direct distal facial muscle excitation was excluded by the absence of single pulse response (SPR) and by longer onset latency (more than 10 ms). FMEP from the orbicularis oris (o.oris) and the mentalis muscle simultaneously can improve the accuracy and success rate compared with FMEP from the o.oris alone. Using the methods described, we can effectively predict facial nerve outcomes immediately after surgery with a reduction of more than 50% of FMEP amplitude as a warning criterion. In conclusion, along with free-running EMG and direct facial nerve stimulation, FMEP is a useful method to reduce the incidence of facial paralysis as a sequela during CPA tumor surgery.

Revalidation of the Complex Trial Protocol using participant-oriented countermeasures (설문 기반 대응방안을 사용한 복합시행 프로토콜의 재평가)

  • Kim, Hyemin;Song, Inuk;Chang, Eunhee;Kim, Hyun Taek
    • Korean Journal of Forensic Psychology
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    • v.11 no.1
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    • pp.89-115
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    • 2020
  • Traditional deception detection methods had examined the difference of one's autonomic physiological responses through asking crime-related and crime-unrelated questions. There has been a continuing controversy regarding the accuracy and validity of the test, and thus, many researchers were motivated to explore and develop alternative efficient methods of detection in which one of them is known as P300-based Complex Trial Protocol (CTP). The P300-based CTP detects deception through comparing the P300 amplitudes between probe and irrelevant stimuli and is known as a counterstrategy of countermeasures. However, many previous studies have used countermeasures created from Rosenfeld et al.'s work (2008). The present study initially conducted a survey asking open-ended questions about the countermeasure use to acquire participant-oriented countermeasures for the main experiment. Then, the study aimed to evaluate whether the CTP can accurately detect deception even in the use of survey-based countermeasures. We firstly selected a set of participant-oriented countermeasures through survey questions. Then, a total of 50 participants were divided into three groups (innocent, guilty, and countermeasures) and performed the CTP. Those assigned to the countermeasures group covertly performed mental countermeasures during the CTP. The results of P300 amplitude analysis revealed that the guilty group's P300 amplitude of probe stimuli was significantly larger than that of irrelevant stimuli. Countermeasures group also had a significantly larger P300 amplitude for probe stimuli compared to irrelevant stimuli, even in the use of countermeasures. The results of bootstrapped amplitude difference (BAD) showed a detection accuracy rate of 81.25%, 82.35%, 82.35% for the innocent, guilty, and countermeasures groups, respectively. These findings demonstrate that the CTP can obtain a high detection rate in participant-oriented countermeasures and suggest the potential use of the CTP in the field.

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EFFECTS OF LENTINUS EDODES LECTINS ON CYTOKINE GENE EXPRESSION FROM HUMAN PERIPHERAL BLOOD MONONUCLEAR CELLS (표고버섯 렉틴의 사이토카인 생성 양상 및 특성)

  • 이인경;김희선;전경희;김성광;정시련
    • Proceedings of the Korean Society of Applied Pharmacology
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    • 1995.04a
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    • pp.113-113
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    • 1995
  • 본 연구는 표고버섯에서 분리정제한 렉틴 성분(LEL)을 말초혈액 단핵세포(PBMC)에 반응시켜 사이토카인 유도능을 지질다당류(LPS)와 비교하여 역전사효소 중합반응법(RT-PCR)으로 측정하였다. 측정 대상 사이토카인은 IL-1, IL-2, IL-6, TNF$\alpha$ 및 IFN${\gamma}$의 다섯가지였으며 이들을 대상으로 PBMC에 렉틴을 적용하여 1, 8, 24, 48, 72, 96, 120분 등의 시간대에서 반응시켜 사이토카인의 유전자 발현 유도에 관한 다음의 결과를 얻었다. LEL의 사용 농도에 따른 편도선 림프구(tonsillar lymphocyte)의 TNF$\alpha$ 유전자 발현 양상은 반응 1시간의 경우 LEL의 일부 농도와 LPS 전농도에서 관찰되었으나 반응 40시간째에는 LEL 전농도와 LPS 전농도에서 TNF$\alpha$ 유전자 발현 양상을 관찰할 수 없었다. RT-PCR 결과 원액이나 회석액 재료로부터 관찰된 TNF$\alpha$유전자 band의 강 약 차이는 나타나지 않았다. LEL의 자극에 의한 반응 시간대 별 PBMC에 의한 사이토카인 유전자 발현 양상은 위에서 언급된 다섯가지 사이토카인을 유도, 생성할 수 있다는 것이 확인되었는데, IL-2, IL-6 및 IFN${\gamma}$는 120시간까지 장시간 지속되는 유전자 발현이 가능한 반면 TNF $\alpha$의 생성 양상은 이들 사이토카인의 생성 양상과는 판이하게 반응 1, 8 및 24 시간대까지만 TNF$\alpha$ 유전자 발현을 관찰할 수 있었고 IL-1은 72 시간까지 반응을 나타내는 등 특이적 양상을 보였다. 한편 LPS는 실험에 사용된 전 사이토카인의 유전자 발현을 120시간대까지 반응이 유지됨을 관찰하였기에 LPS가 PBMC의 강력한 사이토카인 유도체임을 입증할 수 있었으며 LEL과 다소 상이한 결과를 보였으나 LEL 또한 PBMC로부터 사이토카인을 생성 유지시킬 수 있는 유도체로 작용함을 확인할 수 있었다.

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The Syntheses of charge transfer dyes and nanofiber formation for recognition and sensing (진단/감응용 전하 이동형 색소의 합성 및 나노 섬유의 제조)

  • Jung, Young-Sun;Park, Joon-Bae;Moon, Hee-Jung;Kim, Sung-Hoon;Bae, Jin-Seok
    • Proceedings of the Korean Society of Dyers and Finishers Conference
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    • 2012.03a
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    • pp.48-48
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    • 2012
  • 화학센서는 분석물질과 감응물질간의 화학적 반응을 통해 분석물질을 선택적으로 인지하고 이를 통하여 특정물질을 실시간으로 분석할 수 있는 기술이다. 최근 화학센서로 색소를 이용하여 음이온을 진단/감응하는 기술이 각광 받고 있으며, 더불어 음이온을 선택적으로 인지함에 있어 검출하고자 하는 특정 음이온에 대한 민감도를 높이기 위한 노력이 계속되고 있다. 감응물질로 이용되는 색소는 주로 분자 내 전하 이동형 색소(intramolecular charge transfer dye)로 주위 환경 변화에 민감하게 반응하며, 자극에 따른 변화를 흡수와 발광, 굴절률의 변화 등으로 나타낸다. 또한 다양한 음이온 중 분석물질로써 연구 가치가 큰 음이온에는 플루오린화물(fluoride)이 있다. 이는 플루오린화물이 치아 보호와 골다공증에 중요한 역할을 하는 순기능을 가지는 반면 고농도 상태에서는 불소증(fluorosis)을 비롯한 악영향을 잠재적으로 가지기 때문에 그 양을 인지하는 것이 중요하게 여겨지기 때문이다. 따라서 본 연구에서는 2-(3,5,5-trimethylcyclohex-2-enylidene)-malononitirle과 indole-3-carboxaldehyde를 통하여 분자 내 전하 이동형 색소를 합성하고, $^1H$ NMR, GC-mas, EA로 합성된 색소의 물성을 분석하였다. 우선 반응물인 2-(3,5,5-trimethylcyclohex-2-enylidene)-malononitirle을 합성하기 위해 dimethylfor mamide(DMF) 용매 하에서 isophorone과 malononitrile을 12시간 반응시키고, 얻어진 결과물을 정제한다. 이후 indole-3-carboxaldehyde와 10시간 환류시켜 색소를 얻는다. 합성된 색소는 F 이온 검출에 이용되며, UV-vis 분광법을 이용하여 분석물질에 따른 흡수 정도와 강도 변화를 살펴본다. 연구의 최종적인 목적은 비단 진단/감응 색소의 합성이 아니라 나노 섬유 소재와 색소의 접합을 통해 진단/감응형 나노 섬유를 개발하는 것으로 이를 위해 전기방사법이 이용된다.

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