• The Korean Nurse
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• v.22 no.5 s.123
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• pp.45-47
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• 1983

• KOREAN POULTRY JOURNAL
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• v.41 no.5
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• pp.114-118
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• 2009

• The Korean Nurse
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• v.10 no.5 s.55
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• pp.13-22
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• 1971

• Journal of Genetic Medicine
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• v.5 no.1
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• pp.34-40
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• 2008

Purpose : Preeclampsia is a major cause of maternal and perinatal mortality and morbidity and is considered to be a multifactorial disorder involving a genetic predisposition and environmental factors. Endothelin-1 (ET-1) is a potent vasoconstrictor peptide, and alterations in the ET-1 system are thought to play a role in triggering the vasoconstriction seen with preeclampsia. The aim of this study was to examine the frequency of the 4 common single-nucleotide polymorphisms (SNPs) (c.1370T>G, c.137_139delinsA, c.3539+2T>C, and c.5665G>T) of the ET-1 gene in normotensive and preeclamptic pregnancies and to investigate whether these SNPs are associated with preeclampsia in pregnant Korean women. Methods : We analyzed blood samples from 206 preeclamptic and 216 normotensive pregnancies using a commercially available SNapShot kit and an ABI Prism 3100 Genetic analyzer. Results : There were no significant differences in genotype or allele frequencies of the 4 SNPs in the ET-1 gene between preeclamptic and normotensive pregnancies. The respective frequencies of the 3 haplotypes (TDTG, GDCT, and TICT; >10% haplotype frequency) were 61%, 13% and 13%, respectively, in preeclampsic pregnancies and 62%, 14% and 12%, respectively, in normotensive pregnancies. The frequencies of these haplotypes were similar for both groups. Using multiple logistic regression analysis, we did not observe an increase in the risk of preeclampsia for the 4 SNPs of the ET-1 gene under either a recessive or dominant model. Conclusion : This study suggests that the 4 SNPs of the ET-1 gene are not associated with an increased risk for preeclampsia in pregnant Korean women.

• Environmental and Resource Economics Review
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• v.7 no.1
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• pp.119-150
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• 1997

1990년 동북아 23개 지역의 이산화황 총배출량은 14.7백만톤이었다. 이중 중국동북부가 81%, 한국이 12%, 일본이 5%, 그리고 북한이 2%를 배출하였다. 기본시나리오하에서 동북아지역의 이산화황 배출은 2020년에 40.5백만톤에 이를 것으로 추정되고 있다. 중국에서 배출된 장거리 월경성 대기오염물질은 한반도와 일본으로 이동하며 특히 산성강우는 중국으로부터의 이산화황 배출에 크게 영향을 받고 있다. 산성강우는 자연생태계와 농작물에 피해를 줄 뿐 아니라 인간의 건강에도 심각한 피해를 준다. 따라서 미래의 산성강우 피해를 줄이기 위해서는 자국뿐 아니라 인접국의 이산화황 및 질소산화물 배출도 함께 감소되어야 한다. 동북아지역 국가들은 경제발전단계 및 환경협력 논의에서의 우선순위가 다르기 때문에 가까운 시일내에 환경협력을 위한 다자간 협약을 체결하기는 어려울 것이다. 따라서 ESCAP, APEC 등 기존의 지역협력기구를 이용하거나 IBRD, ADB 등의 다자간 외부금융기관이나 공적개발원조 (ODA) 등을 통해 개선된 환경기준을 준수하도록 하고 지역환경개선을 위한 협력사업을 추진하는 것이 바람직하다. 또한 산성비와 관련한 동북아 환경협력은 과학적 조사를 통해 객관적이고 신뢰할만한 정보를 획득하는 것으로부터 시작하여 단계적으로 추진되어야 하며, 정치, 경제, 과학, 외교 등 여러 분야에 걸쳐 중앙정부 뿐만 아니라 지방정부와 NGO도 포함하는 다차원적, 포괄적으로 추진되어야 한다.

• Water for future
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• v.49 no.5
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• pp.72-76
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• 2016

• Korean Journal of Materials Research
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• v.5 no.4
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• pp.426-432
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• 1995

윤활제인 zinc stearate의 첨가량 (0~4wt%)을 변화시켜 U$O_{2}$분말의 겉보기밀도, 성형시의 분말입자간 마찰과 입자/다이벽 마찰간의 상관관계를 조사하였다. 소량의 윤활제 첨가시에는 U$O_{2}$분말입자간 박막의 윤활제 도포층이 형성되어 겉보기밀도가 증가한 반면 다량의 윤활제를 첨가한 경우에는 U$O_{2}$ 분말입자에 두꺼운 윤활제 도포층이 형성되고 미혼합된 윤활제가 존재하여 겉보기밀도는 감소하는 경향을 보였다. 윤활제를 첨가혼합한 상태에서 다이벽 윤활도포 유무에 따라 구한 U$O_{2}$ 성형체의 성형압력/성형밀도 자료로부터 분말입자간 마찰, 입자/다이벽 마찰 그리고 성형시 lubrication/inhibition등의 상대적 중요성을 조사하였다. 입자/다이벽 마찰에 의한 압력손실은 입자간 마찰에 의한 압력손실보다 크게 나타났다. 입자/다이벽 마찰에 의한 압력손실은 다이벽 윤활제 도포에 의해 최소화될 수 있지만 상대적으로 바람직하지 않은 성형시의 inhibition이 야기되는 것으로 나타났다.

• Journal of Genetic Medicine
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• v.5 no.2
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• pp.105-110
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• 2008

Purpose: Preecalmpsia is a pregnancy-specific disorder that reflects widespread endothelial dysfunction resulting from increases of adhesion molecule expression. Intercellular adhesion molecule-1 (ICAM-1) is involved in the pathogenetic mechanisms responsible for preeclampsia, and ICAM-1 plasma levels and/or function is genetically influenced. Therefore, we evaluated the distribution of ICAM-1 gene K469E polymorphism in pregnant Korean women with preeclampsia and evaluated the association between this polymorphism and preeclampsia. Methods: The K469E polymorphism was analyzed in peripheral blood samples from 197 preeclamptic pregnancies and 193 normotensive pregnancies by a SNapShot kit and an ABI Prism 3100 Genetic analyzer. Results: Genotypic and allelic frequencies of ICAM-1 gene polymorphism (K469E) did not differ between preeclamptic and normotensive pregnancies. The distributions of the KK, KE, and EE genotypes were 40.6%, 43.7%, and 15.7%, respectively, in preeclamptic pregnancies and 38.9%, 45.1%, and 16.1%, respectively, in normotensive pregnancies. The frequencies of K and E alleles were 0.62 and 0.38, respectively, in preeclamptic pregnancies and 0.61 and 0.39, respectively, in normotensive pregnancies. By multiple logistic regression analysis, there was no increased risk of preeclampsia in subjects with ICAM-1 KE (OR, 1.08; P=0.74) or EE (OR, 1.07; P=0.88) genotypes. Conclusion: This study suggests that the ICAM-1 gene K469E polymorphism does not associate with an increased risk of preeclampsia in pregnant Korean women.

• The korean journal of orthodontics
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• v.32 no.1 s.90
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• pp.59-69
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• 2002

The purpose of this study was to evaluate the reproducibility of lateral cephalometric landmarks according to radiographic image enhancement, and to contribute to the identification of cephalometric landmarks. Lateral cephalograms of ten individuals were taken and stored into computer. The images were then enhanced up to four grades by Quick Ceph Image Pro$^{TM}$ on condition that the gray-scale equalization number was 50 and the detail enhancement number was 50. After thirty two landmarks were identified on monitor images by five observers, the deviations from the mean, the distances estimated between identified points and the mean point of five identified points, were evaluated for each landmark at each enhancement grade. Through the statistical analysis, following results were obtained. 1. In case of unenhanced radiographic images, the inter-observer reproducibility of the landmarks showed a large variation. 2. The comparison of deviation from the mean according to the degree of radiographic image enhancement for each landmark showed that the inter-observer reproducibility was significantly different at 5 landmarks. 3. The landmark of pterygomaxillary fissure showed higher reproducibility at enhancement grade 1 and 2 images than at unenhanced images. So did the landmark of posterior nasal spine at enhancement grade 1 images, and the landmark of menton at enhancement grade 2, 3 and 4 images respectively. The above results suggest that the reproducibility of some landmarks can be increased by radiographic image enhancement during the identification of the lateral cephalometric landmarks on the monitor.

• Korean Journal of Construction Engineering and Management
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• v.17 no.5
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• pp.3-12
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• 2016

Recently government is set to expand its policy to promote technical proposal tendering in a dimension of technical competitiveness reinforcement. Because a variety of complicated techniques are applied in technical proposal tendering and variables could be occurred in terms of cost, schedule, constructability and others when techniques are reflected on design document collaboration management among participants is considered insignificantly. So the research would determine primary management factors and presents management direction for collaboration among participants. First action for this is categorization of hindrance factors to collaboration into five factors as 'Poor work processing', 'Communication cap among participants', 'Lack of understanding about technical proposal tendering', 'Difficulty of decision making' and 'Insufficiency in managing the work data'. Second correlation analysis is conducted between the categorized factors and participants according to tasks in technical proposal tendering to figure out the correlation degree of variables. If there is a strong correlation between variables, hindrance factor in that case regarded primary management factor to collaboration and finally management direction is presented at each task.