• Journal of Genetic Medicine
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• v.6 no.1
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• pp.56-61
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• 2009

Purpose: Preeclampsia is a multifactorial disorder with genetic and environmental components. Recently, the STOX1 gene, identified as a candidate gene for preeclampsia in Dutch women, has been shown to be placentally expressed and subject to imprinting with preferential transmission of the maternal allele. The purpose of this study is to investigate whether there is an association between the STOX1 Y153H variation and preeclampsia in Korean pregnant women. Materials and Methods: This study involved 202 preeclamptic and 204 healthy pregnant women who were genotyped for the Y153H variant of the STOX1 gene using a commercially available SNapShot assay kit and an ABI Prism 3730 DNA Analyzer. Results: There were no significant differences in genotype frequencies of the Y153H variant of the STOX1 gene between preeclamptic patients and normal controls (P>0.05). The H allele frequency of the STOX1 Y153H variation was similar in patients with preeclampsia (87.1%) and in normal controls (86.5%). In addition, multiple logistic regression analysis showed that the YH, HH, and YH/HH genotypes were not associated with an increased risk of preeclampsia when compared to the YY genotype. Conclusion: This is the first study to characterize the Y153H variant of the STOX1 gene in Korean patients with preeclampsia. We found no differences in the genotype and allele frequencies between preeclamptic and normal pregnancies. Although limited by a relatively small sample size, our study suggests that the STOX1 Y153H variation is not associated with the development of preeclampsia in Korean pregnant women.

• The Transactions of the Korea Information Processing Society
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• v.5 no.5
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• pp.1140-1150
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• 1998

The objective of this paper is to analyze requirements of distributed applications which use the different type of information and support the cooperative work environment between a group of persons in interactive mode, and to provide useful common services for the development of this kind of applications. For this, Interactive Cooperative Application Service as a horizontal service on the application layer and Session Management Service as a support service on the infrastructure layer were defined and designed using the concepts and rules of the Open Distributed Processing system. Application designers may use these services for building those applications which demand the requirements we have characterized in this paper.

• Proceedings of the Korean Society of Computer Information Conference
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• 2016.07a
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• pp.141-143
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• 2016

2016년 5월 19일 대법원은 전원합의체판결에서 부동산 매수자가 본인 명의로 소유권이전등기를 하지 않고 등기를 매도인에게서 직접 명의수탁자로 이전하는 제3자간 명의신탁(중간생략등기형 명의신탁)의 경우 명의수탁자가 신탁부동산을 임의로 처분하여도 형사처벌를 할 수 없다는 판결을 하였다. 본 논문에서는 민법과 형법의 교차영역인 명의신탁에서 민사사건의 형사화를 지양했다는 점에서 긍정적인 평가를 하지만 이에 따른 관련법의 정비를 통한 법개정을 제안한다. 즉, 명의신탁에 관한 법제 간 모순을 극복하기 위해 '부동산 실권리자명의 등기에 관한 법률'의 개정이 요구된다. 또한 부동산소유자가 그 등기명의를 타인에게 신탁하기로 하는 명의신탁약정을 맺고 그 등기명의를 명의수탁자에게 이전하는 소위 2자간 명의신탁의 경우도 비범죄화를 함으로써 법체계의 논리성과 통일성을 확보할 필요가 있다.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.32 no.5D
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• pp.493-498
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• 2012

Korean construction companies have maintained stable market share based on high technology and cost competitiveness although international construction market has been stalled due to increasing global economy uncertainties. However, Korean construction companies have relied heavily on the general types of projects in Middle East and Asia although the portion of different types of projects such as Build-Transfer-Operate (BTO), Build-Transfer-Lease (BTL), and Public-Private-Partnership (PPP) has been increasing in the market. When delivering huge projects requiring contractors deal with activities from project planning to operation, securing finance sources and profitability is deemed critical. Therefore, Korean construction companies need more attentions on the construction market supported by Multilateral Development Banks. However, Korean construction companies have not utilized effective strategies for the market entry and also government supportive policies are not useful enough to help construction companies. This study aims both to analyze the contract structure of Korean construction companies for presenting critical factors that need to be prepared and to suggest various methods that can be applied to support construction companies that have much interest in the Multilateral Development Banks. According to the results of study, it is important that Korean government provide structural information system, make a specialized organization, prevent over-heating among Korean construction companies, and collaborate with Official Development Agency. In addition, it appeared that the fairness and financial stability of project have recognized main advantages of the Multilateral Development Banks.

• The Korean Journal of Applied Statistics
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• v.24 no.5
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• pp.861-869
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• 2011

One of the main objects of recent genetic studies is to understand genetic factors that induce complex diseases. If there are interactions between loci, it is difficult to find such associations through a single-locus analysis strategy. Thus we need to consider the gene-gene interactions and/or gene-environment interactions. The MDR(multifactor dimensionality reduction) method is being used frequently; however, it is not appropriate to detect interactions caused by a small fraction of the possible genotype pairs. In this study, we propose a relative risk interaction explorer that detects interactions through the calculation of the relative risks between the control and disease groups from each genetic combinations. For illustration, we apply this method to MDR open source data. We also compare the MDR and the proposed method using the simulated data eight genetic models.

• Journal of Internet Computing and Services
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• v.15 no.5
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• pp.123-132
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• 2014

Internet is composed of many independent networks referred to as Internet Service Providers (ISPs) and each provider is generally interconnected based on a commercial agreement. Though many countries are engaged in deregulation in internet interconnection, there is still debate whether the large ISPs are unwilling to peer with small providers, have incentives to lower the quality of data transmission of transit operators or set the interconnection charge regarding the actual costs incurred by the interconnection. Korean government introduced regulations in internet interconnection after observing noticeable anti-competitive behaviors from 2005. This paper analyzes whether there is margin squeeze problem/market concentration, and suggests political proposals in Korean regulation status.

• The Journal of the Korea Contents Association
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• v.11 no.5
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• pp.308-316
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• 2011

Familial concordance of vascular risk factors is well understood and there are many studies about inter-spouse concordance of the risk factors for coronary heart disease. However, there are no studies for inter-spousal relation of the risk factors in cerebrovascular disease patients. We analysed inter-spouse correlation of cerebrovascular risk factors in patients admitted our hospital due to stroke and their spouses. There was statistically significant inter-spouse concordance in the presence of hypertension(p=0.025) and carotid IMT(r=0.479, p=0.001). However, the further age-adjusted analysis revealed no significant result. Differently from the results of previous studie,, the present study shows no significant spousal concordance. Althought there are tendencies of spousal concordance in some risk factors, the age is major determinant.

• Korean Journal of Construction Engineering and Management
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• v.18 no.5
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• pp.50-58
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• 2017

The efficient communication process is essential to guarantee the completeness of design and secure the quality to meet the contractor's needs. However, using the existing communication methods based on the design and documents, it is difficult to effectively understand the drawings and specifications that are very complicated, and sufficient technical experiences would be required. Ineffective and inefficient communication among users, designers and project participants during the design process would raise the possibility of functional interferences of the object, induce conflicts, cause a design change, and accordingly incur losses of the project in terms of cost and time. The purpose of this study is to suggest improvement direction of communication in accordance with the requirements, by investigating the present state and the project participants' understanding of design communication. And also, it presents the application model of QFD that the project participants could share and define, and feedback the requirements as well as conducting analysis of improvement factors based on the survey.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.37 no.5C
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• pp.365-375
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• 2012

LVC-G COTS SW are widely used for the military training due to several advantages. Accordingly, LVC-G COTS SW domestic developments are in demand. In this study, there are the four hypotheses in the gap between users and developers and establish the hypotheses are all correct. The first hypothesis "LVC-G associated with the COTS SW between users and developers about the requirements for the performance gap is expected.", the second hypothesis, "LVC-G associated with between users and developers for COTS SW technology gap is expected for the elements. ", the third hypothesis" LVC-G associated with the COTS SW development costs between users and developers about the expectations gap is about. ", the fourth hypothesis" LVC for COTS SW-G and related skill levels between users and developers are excited about the gap ". Every hypothesis were confirmed to be valid by interview and survey.

• Communications of the Korean Institute of Information Scientists and Engineers
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• v.14 no.5
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• pp.60-74
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• 1996