• Title/Summary/Keyword: 자가 결합

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Self-Aggregated Nanoparticles of Lipoic Acid Conjugated Hyaluronic Acid (히알루론산에 결합된 리포산 자기조립체의 제조 및 특성)

  • Hong, In-Rim;Kim, Young-Jin
    • Polymer(Korea)
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    • v.32 no.6
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    • pp.561-565
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    • 2008
  • Hyaluronic acid (HA) is a natural glycosaminoglycan and is used widely in the pharmaceutical field. Lipoic acid (LA) helps the regeneration of exogenous and endogenous antioxidants such as Vitamin C and Vitamin E as well as glutathione. It also acts as antioxidant indirectly. Hydrophilic HA as a biodegradable and biocompatible polymer was conjugated with hydrophobic LA as an antioxidant to form the graft copolymer. The carboxyl group of HA was modified by adipic acid dihydrazide (ADH). The synthesis of HA-g-LA graft copolymers was characterized by FT-IR, $^1H$-NMR spectroscopy. The conjugates could form the self-assembled nanoparticles in aqueous solution. The particle size and critical aggregation concentration were verified to use the nanoparticle as a carrier fur the hydrophobic material.

Measurement of Contact Angle and Bond Strength Using 3 Different Self-Etching Primer (3종의 자가부식 프라이머의 상아질계면 접촉각 및 미세인장결합강도에 관한 연구)

  • Chang, Seok-Woo;Kwon, Ho-Beom;Yoo, Hyun-Mi;Park, Dong-Sung;Oh, Tae-Seok;Bae, Kwang-Shik
    • Journal of Dental Rehabilitation and Applied Science
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    • v.24 no.1
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    • pp.105-112
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    • 2008
  • The purpose of this study was to evaluate the contact angle made by 3 kinds of self etching primers (Clearfil SE Bond, AdheSE, and Tyrian) on dentin and to measure the microtensile bond strength of resin composite to dentin using these self-etching primers. Contact angle between each of 3 self etching primers and polished dentin surface was measured (n=30) by contact angle analyzer and the result was analyzed by One-way ANOVA. For the measurement of microtensile bond strength, polished dentin surface was treated with each of 3 self etching primers and dentin adhesives. Z-250 composite resin was built-up with a height of 5 mm on the adhesive-treated surface and light cured for 40s with a halogen light curing unit. Thereafter, each tooth was sectioned into slabs perpendicular to the bonded interface and trimmed (n=45). The microtensile bond strength was measured with universal testing machine and the result was analyzed with Kruskal-Wallis test. AdheSE group showed the highest contact angle followed by Clearfil SE group and Tyrian group (p<0.05). AdheSE group and Clearfil SE group showed significantly higher microtensile bond strength than Tyrian group (P<0.05).

SHEAR BOND STRENGTH OF SELF-ETCHING PRIMER SYSTEMS TO CONTAMINATED DENTIN IN PRIMARY TEETH (오염된 유치 상아질에 대한 자가 부식 프라이머의 결합강도에 관한 연구)

  • Seo, Ju-Hee;Lee, Kwang-Hee;Kim, Dae-Eup
    • Journal of the korean academy of Pediatric Dentistry
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    • v.29 no.1
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    • pp.107-114
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    • 2002
  • The purpose of this study was to determine and compare the shear bond strength of two self-etching primer systems to primary teeth contaminated with saliva and blood. Clearfil SE Bond and AQ Bond were evaluated. One hundred specimens were made by seventy-five deciduous teeth(fifty anterior and twenty-five posterior teeth) and divided randomly into ten groups. Small flat dentinal surfaces were prepared by grinding the buccal, lingual and labial areas. Specific surface treatments were applied to each group: (1) a self-etching primer application(control group), (2) saliva contamination followed by primer(Group I), (3) primer curing followed by saliva contamination (Group II), (4) blood contamination followed by primer(Group III), (5) primer curing followed by blood contamination(Group IV). After bonding of composite resin(Z100, 3M, USA) to contaminated sample surfaces and thermocycling(1,000 cycles), shear bond strengths were measured using Universal Testing Machine(Zwick Z020, Zwick Co., Germany). The results were as follows; 1. Group I showed lower shear bond strength than control group but no statistically significant difference was found(P>0.05). 2. Group II and blood contamination group(Group III & IV) showed significantly lower shear bond strength than control group(P<0.01). 3. The shear bond strength of Clearfil SE Bond was significantly higher than that of AQ Bond(P<0.05).

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Experimental Study on the Acellular Dermal Matrix Graft for the Root Coverage in Dog (성견에서 ADM(acellular dermal matrix)의 치근피개 효과에 관한 실험적 연구)

  • Cho, Min-Young;Lee, Seoung-Ho;Han, Keum-Ah;Lee, Jun-Young;Jeon, Hye-Ran;Kang, Na-Ra;Kim, Myung-Rae
    • Journal of Periodontal and Implant Science
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    • v.36 no.1
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    • pp.239-251
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    • 2006
  • 결합조직이식을 이용한 치근피개 술식에 많은 관심이 집중되고 있다. 최근에는 acellular dermal matrix가 자가 결합조직 이식편의 대체물로써 소개되었다. 본 실험의 목적은 치근피개를 위해 acellular dermal matrix을 사용시, 그 임상 효과 빚 조직 치유 양상을 평가하고, 이를 자가 결합조직 이삭시의 결과와 비교하기 위함이다. 3마리의 성견에 인위적인 치은 퇴축부 형성을 위해서, 상악 좌우견치의 협측에서 각화치은을 모두 제거하고, 법랑백악경계부로부터 12mm 정도 치조골을 삭제한 후에 판막을 봉합하였다. 그 후 35일을 치유 기간으로 부여하였다. 총 6 부위의 결손부가 실험에 포함되었고, 각각 3 부위씩이 대조군과 실험군으로 분류되었다. 실험군에서는 acellular dermal matrix 이식과 치관측 변위 판막을 시행하였고, 대조군에서는 치은 퇴축부위에 자가 결합조직 이식과 치관측 변위 판막을 시행하였다. 치주낭 깊이, 임상적 부착 수준, 치은 퇴축 높이, 각화조직 높이 등을 인위적 결손부 형성전, 치은 피개술 시행 직전, 피개술 시행후 4주 경과시에 각각 측정하였다. 술후 4주시에, 상악 좌우 견치 부위에서 시편을 얻어 조직학적으로 관찰하고 Wilcoxon signed rank test 와 Mann-Whitney U test으로 통계처리하였다. 임상결과 관찰시, 대조군과 실험군 모두에서, 술전과 비교시 치은 퇴축 감소와 각화조직의 증가, 임상 부착수준의 개선이 나타났다.(p ( 0.05) 평균 치근 피개율은 실험군에서 61.33(5.67%(n=3), 대조군에서 55.67(5.67%(n=3) 이었고, 대조군과 실험군에서 임상결과에서는 통계학적으로 유의성 있는 차이는 없었다.(p ( 0.05). 조직학상으로는, 두 군 모두에서 이식편이 수여부에 잘 융화되어 있었고 비슷한 치유 양상을 보였다. 이상의 실험결과에 의하면, Acellular dermal matrix은 치근피개술 시행시에 결합조직 이식편의 대용품으로 사용할 수 있고 비슷한 피개 결과를 얻을수 있었다.

MICROTENSILE BOND STRENGTH OF SELF-ETCHING AND SELF-ADHESIVE RESIN CEMENTS TO DENTIN AND INDIRECT COMPOSITE RESIN (간접 복합레진 합착 시 자가부식형과 자가접착형 레진시멘트의 상아질에 대한 미세인장 결합강도)

  • Park, Jae-Gu;Cho, Young-Gon;Kim, Il-Sin
    • Restorative Dentistry and Endodontics
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    • v.35 no.2
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    • pp.106-115
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    • 2010
  • The purpose of this study was to evaluate the microtensile bond strength (${\mu}TBS$), failure modes and bonding interfaces of self-etching and three self-adhesive resin cements to dentin and indirect composite resin. Cylindrical composite blocks (Tescera, Bisco Inc.) were luted with resin cements (PA: Panavia F 2.0, Kuraray Medical Inc., RE: RelyX Unicem Clicker, 3M ESPE., MA: Maxem, Kerr Co., BI: BisCem, Bisco Inc.) on the prepared occlusal dentin surfaces of 20 extracted molars. After storage in distilled water for 24 h, $1.0\;mm\;{\times}\;1.0\;mm$ composite-dentin beams were prepared. ${\mu}TBS$ was tested at a cross-head speed of 0.5 mm/min. Data were analyzed with one-way ANOVA and Tukey's HSD test. Dentin sides of all fractured specimens and interfaces of resin cements-dentin or resin cements-composite were examined at FESEM (Field Emission-Scanning Electron Microscope). In conclusion, PA and RE showed higher bond strength and closer adaptation than MA and BI when indirect composite blocks were luted to dentin using a self-etching and three self-adhesive resin cements.

Cooperative effect in space-dependent Parrondo games (공간의존 파론도 게임의 협력 효과)

  • Lee, Jiyeon
    • Journal of the Korean Data and Information Science Society
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    • v.25 no.4
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    • pp.745-753
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    • 2014
  • Parrondo paradox is the counter-intuitive situation where individually losing games can combine to win or individually winning games can combine to lose. In this paper, we compare the history-dependent Parrondo games and the space-dependent Parrondo games played cooperatively by the multiple players. We show that there is a probability region where the history-dependent Parrondo game is a losing game whereas the space-dependent Parrondo game is a winning game.

Evaluation Standard on Talker Echo of ISDN Telephone (ISDN 전화기의 송화 에코 평가 기준)

  • 강경옥
    • Proceedings of the Acoustical Society of Korea Conference
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    • 1993.06a
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    • pp.50-53
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    • 1993
  • ISDN에 기초한 음성 서비스가 가능해지고 망이 점차 광대역 ISDN으로 진화함에 따라, ISDN 전화기의 송화자 에코의 적절한 규정이 필요하며, 이는 ISDN 전화기의 송화 및 수화음량정격 및 단말결합손실에 의해 좌우된다. 따라서, 전화기의 송화 및 수화음량정격이 규정되어질 경우, 에코가 없는 전화통화를 할 수 있는 단말결합손실의 규정이 필요하며, 실질적으로 이에 대한 규정은 가중 단말결합손실(weighted terminal coupling loss ; TCLw)과 에코 안정손실(stability loss)로 분류되어 규정될 수 있다. 본고에서는 이와 관련된 국제기준을 고찰하고, 국내기준의 제안과 단말결합손실 및 안정손실의 측정결과에 대해서 기술한다.

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INFLUENCE OF ADHESIVE APPLICATION ON SHEAR BOND STRENGTH OF THE RESIN CEMENT TO INDIRECT RESIN COMPOSITE (치과용 접착제가 복합레진 인레이와 레진시멘트의 결합력에 미치는 영향)

  • Song, Mi-Hae;Park, Su-Jung;Cho, Hyun-Gu;Hwang, Yun-Chan;Oh, Won-Mann;Hwang, In-Nam
    • Restorative Dentistry and Endodontics
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    • v.33 no.5
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    • pp.419-427
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    • 2008
  • This study analyzed the influence of dental adhesive/primer on the bond strength between indirect resin composite and the resin cement. Seventy disc specimens of indirect resin composite (Tescera Dentin, Bisco) were fabricated. And bonding area of all specimens were sandblasted and silane treated for one minute. The resin cements were used with or without application of adhesive/primer to bonding area of indirect resin restoration, Variolink-II (Ivoclar-Vivadent) : Exite DSC, Panavia-F (Kuraray) : ED-Primer, RelyX Unicorn (3M ESPE) Single- Bond, Duolink (Risco) : One-step, Mulitlink (Ivoclar-Vivadent) : Multilinh Primer. Shear bond strength was measured by Instron universal testing machine. Adhesive application improved shear bond strength (p<0.05) But Variolink II and Panavia-F showed no statistically significant difference according to the adhesive application. With the above results, when resin inlay is luted by resin cement it seems that application of dental adhesive/primer is necessary in order to improve the bond strength.

EFFECT OF INTERMEDIATE RESIN HYDROPHILICITY ON BOND STRENGTH OF SINGLE STEP ADHESIVE (중간레진의 친수성이 상아질 접착에 미치는 영향)

  • Kim, Yong-Sung;Park, Sang-Hyuk;Choi, Gi-Woon;Choi, Kyoung-Kyu
    • Restorative Dentistry and Endodontics
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    • v.32 no.5
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    • pp.445-458
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    • 2007
  • The purpose of this study was to evaluate the bond strength of a new Single step system with different curing mode composites, and to evaluate the effect of the intermediate resins which have different hydrophilicity on bonding ability by means of the micro shear bond testing and TEM examination for the adhesive interface. The adhesive used in this study was an experimental single step system (Bisco Inc., Schaumburg IL). Experimental groups were produced by using six kinds of intermediate resin having different hydrophilicity that was hydrophilic, hydrophobic and most hydrophobic resin and as filled or not after applying adhesive. Each experimental group was further divided into two subgroups whether the adhesive was light cured or not. Dual cured composite (Bis Core, Bisco Ltd., Schaumburg, IL) was placed on the adhesive layer as light cure or self cure mode. The results or bond strength were statistically analyzed using one way ANOVA and multiple comparisons are made using Tukey's test at ${\alpha}\;<\;0.05$ level. The results of this study were as follows ; 1. The application of intermediate resin did not increase the bond strength for light cured composite. 2. The bond strength of an experimental adhesive with self cured composite was significantly increased by the application of intermediate resin layer. 3. The bond strength of adhesive was irrespective of the cure or not of itself before intermediate resin layer applied. 4. As applied hydrophilic resin layer was, the initial bond strength was higher than both hydrophobic and most hydrophobic one used but there was no significance. Using a single step adhesive with dual/self cured composite, the incompatibility between both of them should be solved by the application of intermediate hydrophobic resin to reduce the adhesive permeability. However, Single step adhesive can be used in the light cured composite restoration without any decrease of the initial bond strength.

Job Mismatch in Korean Regional labor Market: Matching Efficiency Analysis using Stochastic Production Frontier Approach (한국 지역노동시장에서의 일자리 미스매치에 관한 연구 - 확률변경생산함수를 이용한 결합 효율성 분석 -)

  • Yang, Jun Seok;Jeon, Yongil
    • Journal of the Economic Geographical Society of Korea
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    • v.15 no.4
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    • pp.752-765
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    • 2012
  • We analyze the relation empirically between regional labor market characteristics and job matching efficiency with the adaption of stochastic frontier production function. Our empirical results suggest that, as both the ratio of 50 years-old-job seekers and the level of spatial density increase, job matching efficiencies also rise. In contrast, an increase in the ratio of firms which offer permanent contracts lowers job matching efficiencies. And the job matching efficiency is relatively higher in metropolitan areas. Finally, We find a negative relation between total industrial production and job matching efficiency, which implies that job seekers tend to accept uncongenial jobs in the recessions.

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