• The Journal of Korean Obstetrics and Gynecology
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• v.32 no.2
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• pp.138-147
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• 2019

Objectives: This study was to report clinical effect and safety of Traditional Korean Medical Treatment including Hwangryunhaedok-tang Pharmacopuncture for pregnant woman with low back pain with sciatica. Methods: The patient who suffered from sudden low back pain with sciatica was treated with Hwangryunhaedok-tang Pharmacopuncture, acupuncture, moxibustion, herbal medication and cupping therapy during admission. Visual Analog Score (VAS), Oswestry Disability Index (ODI), McGill pain questionnaire-short form (SF-MPQ) were checked to measure the outcome. Results: After treatment, Visual Analog Score (VAS), Oswestry disability index (ODI), McGill pain questionnaire-short form (SF-MPQ) were considerably improved in this case. Conclusions: The results indicate that Traditional Korean Medical Treatment including Hwangryunhaedok-tang Pharmacopuncture is the effective therapy for low back pain with sciatica during pregnancy.

• The Journal of Korean Obstetrics and Gynecology
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• v.35 no.3
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• pp.137-149
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• 2022

Objectives: The purpose of this study is to report the effect of Korean medicine treatment in a patient with Herpes Zoster (HZ) during pregnancy. Methods: During 12 days of hospitalization, a patient was treated by Korean medicine treatment such as herbal medicine including Gami-danggui-san, acupuncture, cupping and fumigation. To evaluate the effect of treatment, we took pictures of skin lesion and symptoms were measured by Numeric Rating Scale (NRS), Short-Form McGill Pain Questionnaire (SF-MPQ) and 36 item Short Form Health Survey (SF-36). Results: After Korean medicine treatment, most of vesicles disappeared. NRS of chief complaints such as neuralgic pain and itchness changed 7-8 to 0 and therefore, quality of life of the patient was elevated sharply. Conclusions: This case shows that Korean medicine treatment is beneficial and safe for the patients who suffered from Herpes Zoster during pregnancy.

• Journal of Nutrition and Health
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• v.14 no.3
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• pp.129-135
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• 1981

Low phenylalanine diet(0.05%) was given to the Sprague Dawley pregnant rats at the 14 days of gestation and continued until the pups were lactated for 11 days. Body weight, plasma phenylalanine and tyrosine, brain weight, and brain phenylalanine and tyrosine were determined on pups randomly sacrificed at several intervals. Body weight of pups on normal diet (0. 36% phenylalanine) gained rapidly while the pups on the phenylalanine deficient diet decreased and did not survive during the period of 11 days. Brain weight of the pups on the phenylalanine deficient diet was significantly lower(P < 0.05) than the normal pups. Phenylalanine deficient diet did not affect the level of plasma phenylalanine of pups, but it seems that there was a positive correlation between the level of phenylalanine in the diet and the plasma tyrosine level. The plasma tyrosine level of pups on the deficient diet was decreased significantly during the Period while the pups on the normal diet increased steadily. Phenylalanine and tyrosine level in the brain was lower in Pups on the deficient diet than the pups on normal diet but the plasma phenylalanine level was not significantly different in both diets. However, plasma tyrosine level was significantly lower in the pups on the deficient diet than the normal diet at the end of the period.

• Toxicological Research
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• v.21 no.2
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• pp.167-173
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• 2005

Bisphenol A (BPA) is a monomer used in the manufacture of a multitude of chemical products, including epoxy resins and polycarbonate. The objective of this study was to evaluate the effects of BPA administration on reproductive characteristics and blood hematological and chemical values in offspring of pregnant dams treated with BPA. BPA was administrated to pregnant mice by intraperitoneally injection with 0, 0.05, 0.5 and 5.0 mg/kg B.W. for 5 times at 3 days interval on gestation days 1-16. There were no treatment-related effects of BPA on reproductive organ weight in male offsprings at 45 days-of-age, but body weight was the lowest in 5.0mg BPA group when compared to other groups (P<0.05). No differences in semen characteristics (sperm concentration, viability, motility and abnormality) were observed between the control and BPA treatment groups. The WBC, HB, HT, MCV, MCH, MCHC, albumin, BUN and total protein of blood hematological and chemical values in male offsprings were not difference for any treatment groups, but RBC value in BPA groups was significantly increased comparing to the control group (P<0.05). The PLT value was slightly higher in 5.0mg BPA groups than in any other group, but not significantly difference among the experimental groups. In female offsprings, the effects of BPA didn't affect to the body and ovary weight, but the uterus weight in 5.0mg BPA group was slightly heavier than that of control group (P>0.05). No statically significant difference in blood hematological values in female offsprings were observed between the control group and BPA groups, but the concentration of albumin and BUN were significantly higher in 0.5mg BPA group when compared to control and other BPA treatment groups (P<0.05). The histological evaluation of testis and ovary in growing offspring at 45 days-of-age was not difference between the control group and BPA groups, but endometriosis of the uterus in female offspring was dramatically increased in 0.5 and 5.0mg BPA groups. These founding suggest that low concentration of BPA might not have a important role on reproductive ability or blood metabolite in offspring of pregnant dams treated with BPA.

• Journal of Embryo Transfer
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• v.17 no.1
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• pp.7-12
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• 2002

This study was carried out to investigate the possibility of porcine artificial insemination (A·I) on fertilizing capacity using intrauterine inseminator (IUI) method and conventional A·I (CAI) method. Number of sows used in this study was 15 far IUI and 59 fur (CAI), respectively. The results obtained are as fellows: 1 . The frozen and liquid semen used for A·I showed the higher farrowing rate in liquid semen (86.4%) than frozen semen (67%). Number of pigs born per semen type showed the higher values of number of piglets with no statistical significance using frozen semen (9.7) than liquid semen (9.3). 2. The farrowing rate per parity was highest in the 3∼5th parities (100%), f311owe4 by 0∼ 2th parities (60%), and was the smallest in 6 ∼ 10th parities (25%). Number of pigs born per litter was highest in 0∼2th parities (11.3), followed by 3 ∼ 5th parities (9.2) and lowest in 6∼ 10th parities. In the number of pigs bort per litter, the sow s in the high parities delivered lower number of piglets than those in low parities with no significant difference. These results indicated that fertilizing capacity could be improved by using IUI method.

• Clinical and Experimental Reproductive Medicine
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• v.33 no.3
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• pp.149-157
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• 2006

Objective: This study was to investigate the clinical efficiency of clomiphene citrate/GnRH antagonist protocol comparing with the clomiphene citrate only protocol in infertile women with normal ovulatory cycles. Method: Among 116 patients, 43 were received assisted reproductive technologies using natural ovulatory cycle, 38 and 35 were received clomiphene citrate only protocol and clomiphene citrate/GnRH antagonist combined protocol, respectively, and the clinical results were compared and analyzed Results: In each group, basal levels of LH, FSH, $E_2$ and FSH, $E_2$ on hCG day injected were not different, but LH level and endometrial thickness on hCG injected day were decreased significantly and the pregnancy rate was increased significantly in clomiphene citrate/GnRH antagonist group. Conclusion: The pregnancy rate was increased significantly in clomiphene citrate/GnRH antagonist group compared with natural ovulatory cycle and clomiphene citrate only group.

• Proceedings of the KSAR Conference
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• 2002.06a
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• pp.77-77
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• 2002

본 실험은 한우 종빈우의 임신말기에 Se과 Vit. E 투여가 종빈우의 분만 후 번식기능에 미치는 요인을 검토하였고, 임신말기 Se과 Vit. E 를 투여한 한우 종빈우에서 태어난 송아지의 발육능력을 조사하고, 혈액화학치와 혈중 Vit. E 농도에 미치는 영향을 검토하였다. 1. 분만 l 개월전 Se과 Vit E 을 투여한 한우 종빈우에서 태어난 송아지의 발육성적을 조사한 결과, 생시체중은 투여구가 대조구보다 높은 성적을 나타냈다 (P＜0.05). 또한 이유시 체중과 일당증체량도 투여구가 대조구 보다 다소 높은 성적을 나타냈으나 처리구간 유의적인 차이는 인정되지 않았다 (P＞0.05). 한편 종빈우의 번식능력을 조사한 결과, 투여구가 대조구보다 초발정이 빨리 도래하였고, 수태 당 인공수정 횟수도 적었으나, 처리구간 유의적인 차이는 인정되지 않았다 (P＞0.05). 2. Se과 Vit. E를 분만 2 개월전 4 회 투여한 한우 종빈우로부터 태어난 송아지의 발육성적을 조사한 결과, 생시체중, 이유시체중 및 일당증체량은 투여구가 대조구보다 높은 성적을 나타냈으나, 처리구간 유의적인 차이는 인정되지 않았다 (P＞0.05). 한편, 한우 종빈우의 번식능력을 조사한 결과, 분만 후 초발정은 투여구가 대조구보다 초발정 발현이 빨랐으며 수태 당 인공수정 횟수는 투여구가 대조구에 비해 적었으나 처리구간 유의적인 차이는 인정되지 않았다 (P＞0.05). 3. Se과 Vit. E를 분만 1개월전 2 회 투여한 한우 종빈우에서 태어난 송아지의 혈액성분에 미치는 영향을 검토한 결과, 평균 혈중 albumin 은 Vit. E 2000IU 투여구가 여타구보다 높은 성적을 나타냈으며 (P＜0.05), 평균 혈중 cholesterol이 함량 또한 Vit. E 1500IU 투여구가 여타구보다 높게 나타났다 (P＜0.05). 그러나 혈중 BUN, creatinine, glucose, IP, calcium, TP 및 triglycerides 함량은 처 리 구간 유의 적 인 차이 는 없었다 (P＞0.05). 4. Se과 Vit. E를 분만 2 개월 전 4 회 투여한 한우 종빈우에서 태어난 송아지의 혈액성분에 미치는 영향을 검토한 결과, 평균 혈중 albumin, cholesterol, BUN, creatinine, glucose, IP, calcium, TP 및 triglycerides 함량은 모든 처리구에서 유의적인 차이가 인정되지 않았다 (P＞0.05). 5. 분만 l 개월 전 Se과 Vit. E를 투여한 한우 종빈우로부터 태어난 송아지의 혈중 Vit. E 농도를 측정한 결과, 평균 혈중 Vit. E 농도는 투여구가 대조구보다 다소 높은 농도를 나타냈으나 처리구간 유의적인 차이는 없었다 (P＞0.05). 6. 분만 2 개월 전에 Se과 Vit. E를 투여한 한우 종빈우로부터 태어난 송아지의 혈중 Vit. E 농도에 미치는 효과를 검토한 결과, 투여구가 대조구보다 다소 높은 농도를 나타냈으나 처리구간 커다란 차이는 없었다 (P＞0.05).

• Journal of the Korea Academia-Industrial cooperation Society
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• v.13 no.4
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• pp.1566-1573
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• 2012

In this study, a survey was carried out on 200 23-year old unmarried men and women attending j university in j city from October 4 to October 7, 2011 to figure out pre-parents' perception of parental role and view of children, and put forward the necessity of pre-parent education by providing opportunities for pre-parent education. The results are summarized as follows. First, the perception of general parenting and parental role showed that 'parenting' is the highest, following by 'parental role'. For women, nuclear families and large families, who feel much necessity of pre-parent education in the academic liberal arts, the perception of general parenting, parental role and parenting by sub-factors was positive. Second, the perception of general view of children showed that 'children plan' is the highest, followed by 'pregnancy and birth.' For those surveyed, who have a plan for marriage and children plan or feel much necessity of pre-parent education in the academic liberal arts, the perception of general view of children, children plan by sub-factors, and pregnancy and birth was relatively positive. As for findings stated above, for pre-parents in their 20s~30s, women' perception of parental role and view of children was more positive than men'. And nuclear families' or large families' perception was more positive than single parent families'. These findings confirm there is a difference between parental role and view of children according to growth environments of pre-parents in social realities that the low birth rate is growing.

• Journal of Nutrition and Health
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• v.39 no.5
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• pp.467-475
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• 2006

The necessity of adequate pregnancy weight gain for optimal pregnancy outcome has been recognized. However, the specific components of pregnancy weight gain that might be critical for fetal growth and development have not been elucidated clearly. The purpose of this study was to investigate the correlation of pregnancy weight gain and birth weight with serum leptin levels in women delivered newborns. The subjects were recruited from K university hospital. The subject's characteristic data (age $32.1\;{\pm}\;4.3\;y$, gestational age $39.5\;{\pm}\;1.1wk$, pre-pregnancy weight $58.0\;{\pm}\;8.6\;kg$, pregnancy weight gain $12.7\;{\pm}\;5.5\;kg$, newborn's birth weight $3.5\;{\pm}\;0.5\;kg$) were gathered. Maternal dietary assessment was carried out at the end of pregnancy. After delivery, blood samples were collected from 20 mother-newborn pairs. Serum levels of various lipids and leptin were analyzed. Maternal daily consumption of iron, zinc, folate were lower than the RDA of each nutrient and index of nutritional quality was less than 1 showing that the quality of maternal diet was low. The levels of serum leptin of mothers and infants were $10.2\;{\pm}\;6.7\;ng/ml$ and $1.7\;{\pm}\;0.6\;ng/ml$, respectively. The serum leptin concentrations of male infants $(1.9\;{\pm}\;0.7\;ng\;ml)$ were not different from that of females $(1.7{\pm}0.5\;ng/ml)$. A negative correlation was found between the maternal pre-pregnant BMI and weight gain during pregnancy (r = -0.54, p < 0.05). There was a positive correlation between the pregnancy weight gain and the newborn's birth weight (r=0.59, p < 0.01 There were also positive correlation between newborn's birth weight and newborn's serum leptin levels (r = 0.57, p < 0.01). No correlations were found between maternal serum leptin levels and that of newborn's. Efforts should be made to attain adequate diet and weight gain during the pregnancy to reduce the likelihood of low or over birth weight of newborns.

• Child Health Nursing Research
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• v.20 no.4
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• pp.247-254
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• 2014

Purpose: Maternal-fetal attachment in a pregnant woman is important for her health and for her child's emotional stability. This study was done to identify the contribution of maternal fatigue, social support, and Taegyo to maternal-fetal attachment based on a survey of pregnant women. Methods: The study was a descriptive correlation study. Participants were 211 from two women's health clinic centers. Data were analyzed using t-test, ANOVA, Pearson correlation coefficients and stepwise multiple regression. Results: Mean scores for maternal-fetal attachment, Taegyo, maternal fatigue, and social support were 93.74 (range 25-125), 64.76 (17-85), 24.12 (10-40), and 54.43 (22-132), respectively. There were significant differences in maternal-fetal attachment according to parity, breast feeding experience, and putting prenatal education into practice. Multiple regression analysis showed that the key determinants of maternal-fetal attachment, were Taegyo (${\beta}$=.67), maternal fatigue (${\beta}$=.21), and social support (${\beta}$=.13), and these explained 55% of the total variance of attachment. Conclusion: The results suggest a need to encourage Taegyo in prenatal management program and provide methods for fatigue resolution and promotion of social support.