• Clinical and Experimental Reproductive Medicine
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• v.33 no.3
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• pp.179-187
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• 2006

Objectives: The risk of aneuploidies of embryos increases in advanced maternal age or parental karyotype abnormality and it results in poor reproductive outcomes such as recurrent spontaneous abortion (RSA) or repeated implantation failure (RIF). Preimplantation genetic diagnosis for aneuploidy screening (PGD-AS) can be applied for better ART outcome by selecting chromosomally normal embryos. The aim of this study is to evaluate the clinical outcome of PGD-AS and which group can get much benefit from PGD-AS among the patients expected to have poor reproductive outcome. Methods: In 42 patients, 77 PGD cycles were performed for aneuploidy screening. Patients were allocated to 3 groups according to the indication of PGD-AS: group I-patients with old age (${\geq}37$) and RIF more than 3 times (n=11, mean age=42.2 yrs.), group II-patients with RSA (${\geq}3$ times) associated with aneuploid pregnancy (n=19, mean age=38.9 yrs.), group III-parental sex chromosome abnormality or mosaicism (n=18, mean age=29.6 yrs.) including Turner syndrome, Klinefelter syndrome and 47, XYY. PGD was performed by using FISH for chromosome 13, 16, 18, 21, X and Y in group I and II, and chromosome X, Y and 18 (or 17) in group III. Results: Blastomere biopsy was successful in 530 embryos and FISH efficiency was 92.3%. The proportions of transferable embryos in each group were $32.5{\pm}17.5%$, $23.0{\pm}21.7%$ and $52.6{\pm}29.2%$ (mean ${\pm}$ SD), respectively, showing higher normal rate in group III (group II vs. III, p<0.05). The numbers of transferred embryos in each group were $3.9{\pm}1.5$, $1.9{\pm}1.1$ and $3.1{\pm}1.4$ (mean ${\pm}$ SD), respectively. The clinical pregnancy rates per transfer was 0%, 30.0% and 20.0%, and it was significantly higher in group II (group I vs. group II, p<0.05). The overall pregnancy rate per transfer was 19.6% (10/51) and the spontaneous abortion rate was 20% (2/10) of which karyotypes were euploid. Nine healthy babies (one twin pregnancy) were born with normal karyotype confirmed on amniocentesis. Conclusion: Our data suggests that PGD-AS provides advantages in patients with RSA associated with aneuploidy or sex chromosome abnormality, decreasing abortion rate and increasing ongoing pregnancy rate. It is not likely to be beneficial in RIF group due to other detrimental factors involved in implantation.

• Journal of the Korean Dietetic Association
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• v.14 no.1
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• pp.77-86
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• 2008

In Korea, delivery of preterm has increased gradually, preterm delivery rate was 6.4% in 1995 and 9.8% in 2002. The purpose of this study is to provide guidelines for preventing preterm delivery in aspect of health factors and food habits. The health factors and dietary habits were compared between preterm delivery group and full-term delivery group on to recognize risk factor of delivering premature. The results obtained are summarized as follows. The full-term delivery group showed a high rate of professionals and the preterm delivery group showed a high rate of the service industry, showing differences in kinds of occupation(p<0.05). Heights were higher in full-term delivery group(p<0.05). Among the nutrition supplements, iron supplement consumption was the most, period of the intake of iron was significantly longer for the full-term delivery group than for the preterm delivery group(p<0.05). Also, prevalence of coffee was higher in preterm delivery group(p<0.001). The activity level was higher in full-term delivery group(p<0.005).

• Journal of the Korea Institute of Information and Communication Engineering
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• v.15 no.7
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• pp.1487-1494
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• 2011

In this paper, a novel genre classification algorithm is proposed for music recommendation system. Especially, to improve the classification accuracy, the band-pass filter for octave-based spectral contrast (OSC) feature is designed considering the psycho-acoustic model and actual frequency range of musical instruments. The GTZAN database including 10 genres was used for 10-fold cross validation experiments. The proposed multiple-octave based OSC produces better accuracy by 2.26% compared with the conventional OSC. The combined feature vector based on the proposed OSC and mel-frequency cepstral coefficient (MFCC) gives even better accuracy.

• The Journal of Korean Medicine
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• v.41 no.3
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• pp.180-190
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• 2020

Objectives: The purpose of this study was to report the treatment progress of a pregnant women who were treated with Korean medical hospitalization due to threatened abortion in first trimester and plecenta previa in second trimester during pregnancy. Methods: A 36-year-old pregnant woman was hospitalized twice at 9 and 19 weeks of pregnancy due to threatened abortion in first trimester and plecenta previa in second trimester. The patient was prescribed Korean Medicine(Gamidanggui-san, Gamibosaeng-tang) and treated with acupuncture, moxa. Global Assessment(G/A) of bleeding volume and frequency, Numerical Rating Scale(NRS) of abdominal pain, Visual Analogue Scale(VAS) of symptoms was assessed during hospitalization days. Results: Amounts of bleeding, abdominal pain decreased, and other symptoms improved during hospitalization days. The patient maintained her pregnancy until 31^st gestational week and gave a birth by Cesarean section. After giving birth, mother and infant are both in good health. Conclusions: This study suggests Korean medicine treatment has effectively reduced uterine bleeding and helped maintain pregnancy.

• The Journal of Korean Physical Therapy
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• v.15 no.4
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• pp.431-441
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• 2003

Pregnancy and puerperium are associated with significant changes in pschological and physiologic health status. Back and pelvic pain is common in pregnancy with prevalence figures in the range of $48\%-90\%$. The pain starts during pregnancy and often disappears soon after childbirth. But the prevalence of such pain four to six months post postpartum is report to be $25-40\%$. In $10-15\%$ of the case the pain become chronics, that is persisting for more than three months after childbirth. Low back pain and pelvic pain maybe caused by several factors related to changes that occur naturally during pregnancy. Changes in the center of gravity can create a strain on weight-bearing structures in bone. Pregnancy related hormones, relaxin, create general laxity of collagenous tissue. Another factor found to be a possible primary or contributing cause for law back and hip symptoms are leg length inequality, weight gain and changes in foot function. This article outlines the physiological and biomechanical changes that occur during pregnancy which have been reported to be possible causes of low back and pelvic pain And then, examination, diagnosis, evaluation and treatment of the woman during pregnancy are described. Standard treatment for low back pain and pelvic pain in pregnancy includes education in anatomy and kinesiology, back-strengthening exercise, training of the abdominal muscles and body posture correction. So, most woman during pregnancy require individual consultation and physiotherapist.

• Journal of TMJ Balancing Medicine
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• v.9 no.1
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• pp.24-34
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• 2019

It was observed in the Subfertility Cases that Customized yinyang Balance Appliance (CBA) and Balancing Upper Cervical Alignment Technique of functional cerebrospinal therapy (FCST) for meridian and neurologic yinyang balance are theraputic. Four Subfertility cases were managed with the CBA, combined with acupuncture and herb-medicine. The other cases were managed with the Balacing Upper Cervical Alignment Technique, combined with acupuncture and herb-medicine. Clinical outcome measurement was based on subjective measures and clinical observations. Patients showed positive changes in subjective symptoms after the treatment and these effects maintained over the follow-up period. And each patient gave a birth to a male/female child. Further clinical and biological research with FCST therapy on hormone-related disordres is expected.

• Korean Journal of Acupuncture
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• v.25 no.1
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• pp.51-60
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• 2008

Objectives : The aim of this study was to investigate the mechanism and the clinical significance of prohibition of acupuncture of LI4 and SP6 during the period of pregnancy. Methods : It was investigated the prohibition of acupuncture during the period of pregnancy based on the literature reviews. Previous studies identified the acupuncture treatment of animal and clinical studies during the period of pregnancy and labor in China Academic Journal(CAJ). These papers were classified and investigated to clarify the rationale of the prohibition of acupuncture during the period of pregnancy. Results and Conclusions : The contraindicated points during the period of pregnancy are Hapgok (LI4), Samumgyo (SP6), Songmun (CV5), Kwanwon (CV4), Sosang (LU11), Chium (BL67), Kollyun (BL60). The uterine contraction can be induced by the stimuli of Hapgok (LI4) via endocrine system and Samumgyo (SP6) via nervous system. Both Hapgok (LI4) and Samumgyo (SP6) also can be used in various diseases such as induction of abortion, facilitation of parturition, stabilization of embryos, cross birth and so on.

• Korean Journal of Veterinary Research
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• v.34 no.1
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• pp.173-180
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• 1994

Milk progesterone concentrations were measured in 111 dairy cows for confirming the estrus observation and for the early pregnancy diagnosis. Of the 56 cows inseminated, 52 cows(92.8%) were an ovulatory estrus, 2 cows(3.6%) were an unovulatory estrus, and 2 cows(3.6%) were the error of estrus observation, respectively. Milk progesterone concentrations at 21 and 24 days after artificial insemination were significantly higher in 23 pregnant cows compared with those in 5 non-pregnant cows(P<0.05). The accuracy rate for early pregnancy diagnosis in 27 cows achieved when the discriminatory concentration at 21 days after artificial insemination was placed at 2.0 ng/ml skim milk, was 91.3% for positive diagnosis and 100% for negative diagnosis, respectively. These results indicated that milk progesterone determination at 0, 6 and 21 days after artificial insemination can be utilized for confirming the estrus observation and for early pregnancy diagnosis. In conclusion, milk progesterone determination is useful diagnostic tool for monitoring the reproductive performance.

• Imaging Science in Dentistry
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• v.38 no.3
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• pp.177-182
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• 2008

A 27-year-old female was referred to our hospital postpartum due to rapid aggravation of facial swelling. She was diagnosed with osteomyelitis on clinical, radiological, and histopathological examinations, but the possibility of malignancy was not excluded. Clinical signs and symptoms such as facial swelling and discomfort were improved with four months of antibiotics treatment. This is as case of an osteomyelitis progressed from infected extraction socket in a woman with physiological changes of pregnancy. Decreased immunological response, increased sex hormone and calcium regulatory hormones regulate the response of the bone infection. We report this case for helping the diagnosis of unusual from of osteomyelities in pregnancy and postpartum.

• The Journal of Korean Obstetrics and Gynecology
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• v.20 no.1
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• pp.258-267
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• 2007

Purpose : Generally dermatitis is treated by corticosteroids, antihistamines ect, but the use of these drugs may affect pregnant women adversely. In this case Oriental medical therapy can be very useful. The purpose of this study is to report clinical management of dermatitis patients during pregnancy by oriental medicine including Hwa-acupuncture and herbal-combined extraction. Methods : We experienced two cases of dermatitis patient during pregnancy. In the beginning of treatment, they had severe itching, burning sensation, bulls, papule. We teated them with Hwa-acupuncture, herbal-combined extraction. Results : After quite short oriental treatment including Hwa-acupuncture and herbal-combined extraction, the symptoms of patients are remarkable alleviated. Conclusion : We think that many case of dermatitis during pregnancy can be managed effectively by Hwa-acupuncture and herbal-combined extraction. If we make more studies about disease under pregnancy condition, it will bring the high satisfaction of patient and the elevation of treatment rate.