• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.16 no.5
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• pp.205-212
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• 2016

Recently, researches for the integration and standardization of clinical data in the Western medicine and Korean medicine is in progress. If an integration of similar clinical data as well as heterogeneous clinical data is possible based on one standardization, we can able to derive implicit medical knowledge from integrated clinical data. In this paper, we implemented Korean clinical database based on internationally known CDISC standardization to efficiently store Korean clinical data and constructed E-CRF system for convenient data input in clinical sites. Furthermore, we showed example of an integration of Korean clinical data from 4 clinical sites. The results of our study will help to establish the foundation for the extraction of implicit medical knowledge from integrated clinical data. Also, our results may support efficient management through data integration, prevention of repetitive or unnecessary clinical trials, facilitation of collaborative study and convenient research through the distribution of refined clinical data.

• Journal of radiological science and technology
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• v.33 no.3
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• pp.193-201
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• 2010

This study aimed to develop an open clinical training program to improve radiology graduates' clinical competency in the hospital setting to raise quality of patient-centered medical service. Development of the training program is similar to that of an instructional system design model. The program was developed according to the ADDIE model. Elements of each phase were collected. Draft of the program was constructed from literature review and clinical demands. Preliminary training program was implemented to sample students with the draft. After consultation with related professionals, the program was modified and completed. Professional groups assessed content validity of the program. Five continuous phases of the program - analysis, design, development, implementation, and evaluation - accommodate changes in clinical environment and demands. They also provide adequate learning needs. Effectiveness of the program and appropriateness of contents in each phase achieved a satisfactory level of significance. This program reflected demands from medical fields and effective learning programs. The purpose of the open clinical training program is to train radiological technologists in clinical setting to actively engage in patient-centered medical service and to help utilize their professional knowledge.

• The Journal of the Convergence on Culture Technology
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• v.6 no.2
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• pp.139-143
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• 2020

Purpose: This study was conducted to examine the effects of a strength coaching program on nursing students' clinical competence, self esteem, and practice satisfaction. The study was designed using a nonequivalent control group pretest-post test design, and data were collected between January 7 and February 1, 2019. The participants consisted of 41, 3-year nursing students in G City who were assigned to an experimental group (n=21) or a control group (n=20). The data were analyzed using descriptive analysis, a t-test, χ² test, and paired t-test with the SPSS/WIN 21.0 program. After receiving the strength coaching program, a difference was observed in self esteem(t=5.53, p<0.038), and practice satisfaction (t=7.66, p<0.019) of the experimental group. The results of this study indicate that the strength coaching program was effective at increasing self esteem and practice satisfaction in nursing students.

• Journal of the Korea Convergence Society
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• v.10 no.10
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• pp.291-300
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• 2019

This research was conducted to investigate the influence of affective events, affect, and job satisfaction on clinical nurse's turnover intention and to provide guidelines for interventions and strategies to decrease turnover intention. The participants consisted of 296 nurses recruited from three general hospitals in South Korea. Data was collected by a structured self-report questionnaire, and were analyzed using SPSS Statistics 24.0 and AMOS 24.0. The final path model was a good fit for the data based on the model fit indices. In the path analysis, positive events, negative events, positive affect, negative affect, and job satisfaction had statistically significant effects on turnover intention, explaining 37.0% of the variance. This research provided evidence identifying factors influencing turnover intention in clinical nurses. Therefore, findings from this research can be used to design appropriate strategies to decrease the clinical nurse's turnover intention.

• Korean Journal of Clinical Laboratory Science
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• v.52 no.4
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• pp.310-316
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• 2020

Microarray technology represents a critical new advance in molecular cytogenetics. The development of this approach has provided fundamental insights into the molecular pathogenesis in clinical cytogenetics and has provided a clue to many unidentified or unexplained diseases. The approach allows a comprehensive investigation of thousands and millions of genomic loci simultaneously and enables the efficient detection of copy number alterations. The application of this technology has shown tremendous fluidity and complexity of the human genome, and has provided accurate diagnosis and appropriate clinical management in a timely and efficient manner for identifying genomic alterations. The clinical impact of the genomic alterations identified by microarrays is evolving into a diagnostic tool to identify high-risk patients better and predict patient outcomes from their genomic profiles. The transformation of conventional cytogenetics into an automated discipline will improve diagnostic yield significantly, leading to accurate diagnosis and genetic counseling. This article reviews cytogenetic technologies used to identify human chromosome alterations and highlights the potential utility of present and future genome microarray technology in the diagnosis.

• Proceedings of the KSRS Conference
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• 2007.03a
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• pp.25-28
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• 2007

본 논문은 KOMPSAT-2호 및 3호의 화상활용 일환으로 임반 단위의 임상정보 추출에 관한 시범연구이다. QuickBird 화상을 통해 획득한 결과를 요약하면, 첫째로 회색단계공발생 행렬(GLCM)에 기초한 질감(texture)매개변수 화상은 소나무림과 잣나무림의 임상판별을 가능하게 만든다. 단, 동령림 조건과 사면 방위에 무관한 상태의 추가연구가 요구된다. 둘째로 Matlab의 분수계(watershed)산법에 기초한 분할화상에서 소나물김과 잣나무림의 수관투명 면적 대소를 파악할 수 있다. 역시 동령림 조건하의 보충 연구가 필요하다. 셋째로 형태배율과 진원도(roundness)에 기초한 소나무림과 잣나무림의 구별에서 진원도에서는 차이의 유의성이 없고, 형태배율에서는 수관둘레의 불규칙에 의해 유의성있게 구분된다. 본 연구의 임상정보 추출기법은 정밀임업의 정량정보 제공에 기여할 것이다.

• Journal of the Korean Academy of Esthetic Dentistry
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• v.26 no.2
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• pp.68-83
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• 2017

With the increasing popularity of dental CAD / CAM, the kinds of materials that can be used and the range that can be utilized are also increasing. One of the biggest advantages of a dental CADCAM is that you can make a final prosthesis with one visit, but in case of zirconia or a complex aesthetic prosthesis, it is often difficult to make it in one day. In this case, temporary PMMA material can be used to provide a temporary crown with aesthetic and functional properties to the patient and can be used as a test crown or template for the final prosthesis. And if you are with a 5-axis milling machine in a clinic, you can make a temporary crown precisely to a large extent in a short time. In this article, various applications and clinical cases of PMMA temporary crown in the clinic will be presented.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.8
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• pp.410-416
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• 2018

The purpose of this study was to investigate the factors affecting the exhaustion of emotional intelligence of clinical dental hygienist and to improve the quality of customer service and effective management of clinical dental hygienist. The results of the study were as follows: 394 clinical dental hygienists working in Jeollabukdo from February 6 to May 31, 2017. Clinical dental hygienist's emotional intelligence showed a significant negative correlation with burnout(r=-.623, p<.001). Self emotion appraisal, others' emotion appraisal, and use of emotion were found to be related factors to exhaustion of clinical dental hygienist..Based on the results of this study, it would be necessary to develop programs to improve the emotional intelligence of clinical dental hygienists, to reduce burnout and to improve the work efficiency of clinical dental hygienists.

• Journal of Digital Convergence
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• v.14 no.9
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• pp.359-367
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• 2016

This study will be used as basic data to hold clinical training effective by researching and analyzing frequency, satisfaction and stress for the clinical practice of dental hygiene course students. The survey was undergone from Feb. 1, 2014 to Mar. 31 for 219 dental hygiene course juniors who had experienced clinical training in 3 year colleges located in Daejeon and Chungcheong Province. From the study, general and university hospital holds the highest satisfaction in clinical practice and dental offices in acquiring skills. Also, a significant difference is shown between the frequency and satisfaction according to clinical training sheets. The highest degree of stress is shown in dental offices for 'toothbrushing training and dental health education' and in general and university hospital for 'patient counselling'. Therefore, consideration should be made to establish the direction of education, standard criteria and evaluation method for student clinical training to raise its effectiveness.

• Korean Journal of Clinical Laboratory Science
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• v.55 no.4
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• pp.298-305
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• 2023

Burkitt's lymphoma is a distinct subtype of non-Hodgkin's lymphoma originating from B-cells that is notorious for its aggressive growth and association with immune system impairments, potentially resulting in rapid and fatal outcomes if not addressed promptly. Optimizing the use of Food and Drug Administration-approved medications, such as combining known safe drugs, can lead to time and cost savings. This method holds promise in accelerating the progress of novel treatments, ultimately facilitating swifter access for patients. This study explores the potential of a dual-targeted therapeutic strategy, combining the bruton tyrosine kinase-targeting drug Ibrutinib and the epidermal growth factor receptor/human epidermal growth factor receptor-2-targeting drug Lapatinib. Ramos and Daudi cell lines, well-established models of Burkitt's lymphoma, were used to examine the impact of this combination therapy. The combination of Ibrutinib and Lapatinib inhibited cell proliferation more than using each drug individually. A combination treatment induced apoptosis and caused cell cycle arrest at the S and G2/M phases. This approach is multifaceted in its benefits. It enhances the efficiency of the drug development timeline and maximizes the utility of currently available resources, ensuring a more streamlined and resource-effective research process.