• Journal of dental hygiene science
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• v.5 no.4
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• pp.199-204
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• 2005

Background : Oral leukoplakia(OL) and lichen planus(LP) are common soft tissue lesions characterized by white plaque or striae with erosion. The clinical characteristics of these diseases are similar but the cause and clinical course of them are very different. I compared OL with LP by analysizing clinical and histopathological characteristics and follow up study. Patients and methods : The clinical analysis of 200 patients with OL and LP was performed by review of dental and medical charts. And H/E slides were examined under the light microscope. we examined H/E slides by the light microscope. The follow up study of patients was performed. Statistical analysis was done using the SPSS/PC WINDOWS (version 13.0). Results : The age distribution of OL was in the range of 13-75 years old being most prevalent in the 5th decade and there was a tendency of male prevalent. The age distribution of LP was in the range of 20-79 years old being most prevalent in the 4th decade and there was a tendency of female prevalent. The most common site of involvement was the buccal mucosa in both diseases. The most common clinical features of OL and LP were white plaque type and white lesion with striae, respectively. In case of LP, the most common clinical sign was tenderness to palpation. Fifteen cases of OL and eight cases of LP showed epithelial dysplasia. Twelve cases of OL recurred after surgery of oral squamous cell carcinoma and 2 cases of LP were transformed into oral squamous carcinoma. Conclusion : There was statistically significant difference in age, sex, clinical signs of patients, frequency of epithelial dysplasia between OL and LP. The Pearson coefficient correlation efficient was 0.51(p < 0.05). The knowledge of the difference between OL and LP can help understand these diseases.

• The Korean Journal of Nuclear Medicine
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• v.31 no.1
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• pp.1-8
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• 1997

뇌성마비는 뇌 발달시기중 초기의 장애로 인하여 운동기능과 자세의 이상 등을 초래하는 질환으로 임상적으로 여러 유형으로 나누어진다. 뇌성마비 환자중에서 MRI 상 롤란도야의 이상소견을 보이는 경우 특이한 임상적 특징을 나타낸다고 보고되어있다. 본 논문에서는 이들을 대상으로 하여 뇌 단일광자컴퓨터촬영에서 나타나는 뇌혈류 이상 소견과 MRI 소견, 그리고 임상양상들을 비교해보고자 하였다. 임상적으로 뇌성마비로 진단된 80여명의 환자중 MRI상 롤란도야에 저산소성 뇌질환의 소견을 보인 7명을 대상으로 하였다. 이들에게 5-10mCi의 Tc-99m-ECD를 정맥주사후 뇌 단일광자컴퓨터촬영을 하였다. 뇌 단일광자컴퓨터촬영상에서는 특히 뇌피질, 선조체, 시상, 뇌간 및 소뇌의 혈류이상 소견을 분석하였고, 이를 MRI 소견 및 임상증상과 비교하였다. 모든 환자들은 만삭 또는 만삭에 가깝게 태어났고, 주산기 아사가 여섯명의 환자에서 있었다. 임상적으로는 긴장성 사지마비로 나타났다. Tc-99m ECD를 이용한 뇌 단일광자 컴퓨터촬영상 롤란도야의 혈류감소는 모두에서 확연하게 나타났다 MRI상에서 롤란도야의 이상소견은 5명에서는 확실하게 나타났고, 2명에서는 의심되었다. MRI상에서 이상소견을 보인 것보다 더 광범위한 부분에서 뇌단일광자컴퓨터촬영상 이상소견이 보였다. 결론적으로, 롤란도야에서 이상소견을 보인 환자는 임상적, 구조적, 그리고 기능적으로 특이한 소견을 보였다. Tc-99m-ECD를 이용한 뇌 단일광자컴퓨터촬영은 매우 민감하게 반영하였고, MRI보다 뇌의 더 광범위한 부위에서 이상소견을 보였다.

• The Journal of the Acoustical Society of Korea
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• v.41 no.1
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• pp.108-113
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• 2022

Speech recognition in noise situation is an important skill for effective communication. Hearing In Noise Test (HINT) has been suggested as a clinical tool to evaluate these aspects. However, this tool has not been used widely in domestic clinics. In this study, psychophysical aspects of HINT and burdens in clinical application were analyzed to improve the applicability of the tool. The difficulty in understanding speech in the elderly population is due to hearing loss based on aging of peripheral and central auditory pathways. As typical clinical cases, HINT scores for young and elderly listeners (20s vs 70s) were compared. Four conditions of HINT test were Quiet (Q), Noise Front (NF), Noise Right (NR), and Noise Left (NL). Quantitative scores showed that the elderly listener required more Signal to Noris Ratio (SNR) values than the younger counterpart in noisy situations. Although both showed Binaural Masking Level Difference (BMLD) effect, the strength was smaller in the elder. However, the age-matched normalized data were not established in detail for clinical application. Confirmed usefulness of HINT and the related improvement in clinical measuring procedure were suggested.

• Journal of the korean academy of Pediatric Dentistry
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• v.26 no.3
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• pp.492-498
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• 1999

Oculodentodigital syndrome(ODD) was first reported by Lohmann in 1920 and termed by Meyer Schwicketath, which they called "dysplasia oculo-dento-digitalis" in 1957. It is somewhat rare heritable disease. ODD is generally inherited in an autosomal dominant pattern with a complex phenotype. The characteristic features are : (1) unique facial features, (2) microphthalmos, (3) syndactyly and camptodactyly of 4th and 5th fingers, (4) osseous anomalies of the middle phalanges of 5th fingers and toes, (5) enamel hypoplasia, (6) dry lusterless hair. We found several occlusal wearing and yellow discoloration of succedaneous teeth, multiple caries lesions, premature loss and pulpal involvement of primary teeth with associated enamel abnormalities caused by generalized enamel hypoplasia in a fairly constant oral finding. Occasionally partial anodontia, microdontia and cleft lip and palate can be manifested. This case, a 9-year-old female with repaired bilateral syndactyly was referred to pediatric dental clinic, Pusan National University Hospital for evaluation of severe attrition of teeth and caries lesions. She had most of the above mentioned typical manifestations of the syndrome. Dental treatment including caries control, stainless steel crown were performed.

• Journal of the korean academy of Pediatric Dentistry
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• v.27 no.1
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• pp.70-76
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• 2000

Congenital biliary atresia with progressive sclerosis of the intra- and extra-hepatic duct system occurs in 1 : 10,000 live births, and has a poor prognosis with an expected survival of less than 5 years. Etiology of biliary atresia is unclear, however, it is believed a genetic or developmental cause. The clinical characteristics include pronounced jaundice, hepatosplenomegaly, pruritus, steatorrhea, xanthomas, growth retardation, portal hypertension, bleedings, ascites and respiratory infections. Oral manifestations have seldom been reported in patients with biliary atresia, but there may be enamel hypoplasia, delayed tooth eruption, and green teeth. Early diagnosis and surgical intervention have decreased morbidity. returned growth and development to normal and improved the prognosis for survival. Authors report the clinical and radiologic characteristics, proper managements about two cases with biliary atresia.

• Childhood Kidney Diseases
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• v.16 no.1
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• pp.21-31
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• 2012

Focal segmental glomerulosclerosis (FSGS) is the name of the primary glomerular disease as well as the terminology to describe the secondary phenomena of any other glomerular diseases. It is characterized by sclerosis, hyalinosis, foam cell infiltration, vacuolar change of podocytes, and halo formation in the glomerulus. Throughout the interstitium, lymphocytes infiltration, tubular atrophy and vascular changes are accompanied. Occasionally, IgM and/or C3 depositions are noted in the sclerotic areas. Electron microscopically, diffuse effacement of foot processes are seen in non-sclerotic area like minimal change disease. Podocyte injury patterns including vacuolar changes are frequently examined. Recently, Columbia group has suggested morphologic classification of FSGS and they demonstrated very good prognosis of tip lesion and poor prognosis of both collapsing and cellular types. However, the pathogenetic classification has been suggested by others; hyperfilteration, podocyte injury, genetic lesions etc. Further studies are necessary to understand and treat this disease.

• Clinical and Experimental Pediatrics
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• v.50 no.9
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• pp.901-904
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• 2007

Purpose : Reversible posterior leukoencephalopathy syndrome is a complex disorder with characteristic clinical and radiologic findings that mainly involve the white/gray matter of the parieto-occipital lobes. The purpose of this study was to determine its clinical and radiological characteristics. Methods : A total of 15 pateints were involved in the study. Their medical records and radiological features of brain MRI were retrospectively reviewed and analyzed. Results : Fifteen pateints were involved. (9 males and 5 females). The patients' ages ranged from 2-20 years (mean age : 10 years). The brain MRI revealed fairly symmetric areas of increased T2 signal involving both white and gray matter of parieto-occipital regions. The condition seemed to be associated with cyclosporin A and steroid therapy or a variety of other conditions in which blood pressure rises acutely. Conclusion : Reversible posterior leukoencephalopathy syndrome is a complicated neurological condition, but a better understanding of this complex syndrome may obviate unnecessary investigations and lead to prompt and appropriate management of the associated problems.

• Journal of the Korean Arthroscopy Society
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• v.17 no.1
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• pp.66-70
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• 2013

Flap tear is a type of displaced meniscal fragments that is often clinically significant lesions requiring surgical intervention. If the displaced tear is located inferomedial to the tibial plateau and incarcerated into the articular capsule, it can be overlooked from preoperative magnetic resonance imaging evaluation and escape detection during arthroscopic examination. In addition, the clinical feature and treatment result of incarcerated flap tear has not been reported. We present 2 cases of medial meniscus flap tear incarcerated into the articular capsule that showed specific clinical features, in order to emphasize the importance of clinical suspicion of such a lesion for accurate preoperative diagnosis.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.8 no.1
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• pp.133-138
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• 1997

Prader Willi Syndrome(PWS) was first recognized and reported by Prader-Willi. The etiology of the syndrome is not fully understood, but 50-70% of the patients show small deletion in chromosome 15. Manifested symtoms vary according to developmental age. In early life, hypotonia, areflexia, feeding difficulties, hypothermia, microgenitalia, hypoplastic scrotum, cryptochordism were observed. But in several years, hypotonia disappears, and polyphagia, decreased satiety, psychomotor retardation, obesity, hypogonadism and short stature become main problems. Behavioural problems including temper and aggressive outbursts, stealing food, hoarding food, and self excoriating skin picking, trichotillomania are more prominent during adolescence and young adulthood. Also, irritable, depressed mood are described. Lots of psychological and behavioural problems explain the reason why psychiatrists have managed and reported this syndrome. However, there has been no official report of PWS in our country. So authors report the clinical characteristics and issues in management of a patient with PWS.

• Journal of the korean academy of Pediatric Dentistry
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• v.27 no.2
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• pp.222-228
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• 2000

Ectodermal dysplasia is a hereditary disease characterized by a congenital dysplasia of one or more ectodermal structures and their accessory appendages. At least 120 subtypes of ectodermal dysplasia have been reported. The disease is usually transmitted as an X-linked recessive trait in which the gene is carried by the female and manifested in the male. Hypohidrotic ectodermal dysplasia is manifested as a triad of defects that include hypohidrosis, hypotrichosis and hypodontia. The characteristic facial features consist of asteatosis, onchodysplasia, sparse and fine blond hair, prominent forehead, a depressed nasal bridge, thick everted lips. The patient may suffer from dry skin, hyperthermia and unexplained high fever as a result of the deficiency of sweat glands. This case report presents detailed procedures of rehabilitating functional and esthetic defect of a 6-year-old boy with hypohidrotic ectodermal dysplasia along with the review of relevant literatures.