• Title/Summary/Keyword: 임상특성

Search Result 2,456, Processing Time 0.032 seconds

Yin-Yang and Five-Element Characteristics of Day Master on Four Time Pillars of Birth in Korean Population with Schizophrenia: A Consilience-Based Holistic Approach (조현병 환자군과 일반 인구군간 출생일간(出生日干)의 음양오행적 특성 비교: 통섭(統攝)적 측면에서의 접근)

  • Tae-Young Hwang;Ji-Eun Lee;Geum-Dan Yi;Yeoung-Su Lyu
    • Journal of Oriental Neuropsychiatry
    • /
    • v.34 no.2
    • /
    • pp.71-82
    • /
    • 2023
  • Objectives: The existing reductionist approach has not reached complete understanding of the cause of schizophrenia. The objective of this study was to investigate yin-yang and five-element characteristics reflected on four time pillars of birth of patients with schizophrenia through comparison with the general population in the perspective of consilience-based holistic approach. Methods: This study was conducted using a random sequential recruitment method for the general population and individuals with schizophrenia aged 18 to 64 based on the exact date and time of birth using structured questionnaires. Relative positional relations of yin-yang and five-element with day master were primarily examined. In addition, the strength of day master with a score range of 0~100 points was assessed through operational score allocation. Results: Of 591 participants, 576 (346: general population, 230: individuals with schizophrenia) were analyzed. Between-group analyses showed no significant difference in the distribution of types of day master (χ2=10.41, df=9, p=0.318). However, significant between-group differences were shown in the distribution of the strength of day master (t=2.14, p=0.032) and frequency of restraining month branch (χ2=5.23, df=1, p=0.022). In logistic regression analysis, 10-point increase on the strength of day master decreased the probability of onset of schizophrenia over the age of 30 by 29.6% (p=0.002; 95% confidence interval, 0.566~0.876). Conclusions: Findings in this study suggest that four time pillars of birth might be associated with schizophrenia through yin-yang and five-element theory and synchronicity principle, implicating the plausibility of consilience-based holistic approach in the determination of risk factors or cause of schizophrenia.

Diagnostic Approach to a Soft Tissue Mass (연부조직 종양의 진단적 접근)

  • Chun, Young Soo;Song, Seung Hyun
    • Journal of the Korean Orthopaedic Association
    • /
    • v.54 no.4
    • /
    • pp.293-301
    • /
    • 2019
  • Soft tissue masses of the extremities and torso are a common problem encountered by orthopaedic surgeons. Although these soft tissue masses are often benign, orthopaedic surgeons need to recognize the key features differentiating benign and malignant masses. An understanding of the epidemiology and clinical presentation of soft tissue masses is needed to develop a practical approach for evaluation and surgical management. Size and depth are the two most important factors on which triage decisions should be based. In a differential diagnosis of a tumor, it is important to know the characteristics of the soft tissue mass through detailed history taking and physical examinations before the diagnostic procedures. A variety of imaging studies, such as simple radiography, ultrasound, magnetic resonance imaging, positron emission tomography, computed tomography, bone scan, and angiography can be used to diagnose tumors. Know the ledge of advantages and disadvantages of each imaging study is essential for confirming the characteristics of the tumor that can be observed in the image. In particular, ultrasonography is convenient because it can be performed easily in an outpatient clinic and its cost is lower than other image studies. On the other hand, the accuracy of the test is affected by the skill of the examiner. A biopsy should be performed to confirm the tumor and be performed after all imaging studies have been done but before the final treatment of soft tissue tumors. When a biopsy is to be performed, careful attention to detail with respect to multidisciplinary coordination beforehand, cautious execution of the procedure to minimize complications, and expedient follow-up and referral to a musculoskeletal oncologist when appropriate, are essential.

Clinical Study for Characteristics of Heart Rate Variability in Stroke Patients (중풍 환자의 심박변이도 특성에 대한 임상적 연구)

  • Lee, ln-whan;Shin, Ae-sook;Kim, Na-hee;Kim, Hye-mi;Shim, So-ra;Kim, Min-kyung;Cho, Seung-yeon;Na, Byung-jo;Jung, Woo-sang;Moon, Sang-kwan;Park, Jung-mi;Ko, Chang-nam;Cho, Ki-ho;Kim, Young-suk;Bae, Hyung-sup;Park, Seong-uk
    • The Journal of the Society of Stroke on Korean Medicine
    • /
    • v.11 no.1
    • /
    • pp.1-8
    • /
    • 2010
  • Objectives : We designed this study to investigate difference of heart rate variability(HRV) according to sex, age, acute or chronic phase, category of stroke, national institute of health stroke scale(NIHSS), lesion of stroke. Methods : 64 subjects were recruited from the patients admitted to the department of oriental medicine at East-West Neo Medical Center, Kyung Hee University from 1 September 2009 to 31 August 2010. We compared heart rate(HR), standard deviation of all normal P-P intervals(SDNN), low frequency(LF), high frequency(HF), LF/HF ratio. Results and Conclusions : 1. LF/HF ratio is significantly different between over-70 and below-70 of age. 2. SDNN is significantly different between acute and chronic stroke patients. 3. In sex, category of stroke, national institute of health stroke scale(NIHSS), lesion of stroke, there are no significantly different among the any values of heart rate variability(HRV).

  • PDF

Relationships Between Premonitory Urge, Tics and Comorbidities in Children and Adolescents With Chronic Tics (만성 틱장애 소아청소년의 전조충동, 틱증상 심각도, 동반질환 간의 관련성)

  • Joo-Han Kwon;Sang-Keun Chung;Jong-Chul Yang;Jong-Il Park;Ha-Min Kim;Tae Won Park
    • Korean Journal of Psychosomatic Medicine
    • /
    • v.31 no.2
    • /
    • pp.142-148
    • /
    • 2023
  • Objectives : The purpose of this study is to investigate the relationships between premonitory urge, tic severity, and comorbidities in children and adolescents with chronic tic disorders. Methods : In this study, scales for tic symptoms, premonitory urge, obsessive-compulsive symptoms, and ADHD symptoms were repeatedly measured twice in 26 children and adolescents aged 10 to 18 years with chronic tic disorders. Correlations between scales were confirmed through repeated measures correlation analysis, and causal relationships between scales were confirmed through regression analysis using a linear mixed model. Results : The degree of premonitory urges showed a significant positive correlation with the severity of tic symptoms, the severity of obsessive-compulsive symptoms, and the severity of ADHD symptoms. The ADHD symptoms showed a significant positive correlation with the severity of tic symptoms. These results were the same even in children and adolescents with tic disorders who were not diagnosed with obsessive-compulsive disorder. Additionally, premonitory urges were found to have a significant positive effect on the severity of tic symptoms. Conclusions : These results may be helpful in treating tic disorders and can be used in future tic disorder research considering developmental trajectory.

Clinical Assessment of Lip Balm Containing Exfoliation Complex to Improve Wrinkles, Elasticity, and Hydration of Lips (입술의 주름, 탄력, 보습 개선을 위한 각질 박리 복합물이 함유된 립밤의 임상 효능 평가)

  • Jiye Park;Jae Young Shin;Jinyong Lee;Myoung Jin An;Nae Gyu Kang
    • Journal of the Society of Cosmetic Scientists of Korea
    • /
    • v.49 no.4
    • /
    • pp.355-364
    • /
    • 2023
  • Lips have a unique desquamation process and moisturizing properties that are structurally different from ordinary skin. In particular, the turnover cycle of the stratum corneum is fast and the outermost stratum corneum is thin, so the amount of keratin is relatively high, and there are no skin appendages, so it is very vulnerable to maintaining moisture. In this study, we set three targets for lip care : stratum corneum, moisture, and barrier, and aimed to identify the potential of three target-specific ingredients for lips improvement. We confirmed the exfoliating, moisturizing, and barrier improvement efficacy of three target-specific ingredients which also have mild exfoliating effect. Specifically, we verified that Bacillus clausii extract improved skin exfoliation, gluconolactone improved skin moisture retention, and serine reinforced skin barrier function. To test the in vivo efficacy of the complex composed of three target-specific ingredients on the human lips, the lip balm manufactured with non-irritating range of concentration was applied, and we confirmed that it was effective in improving lip exfoliation·moisturizing·elasticity·wrinkles. Consequently, it was confirmed that the beauty and health indicators of the lips could be improved through the exfoliation-moisturization-barrier care of the lips and these ingredients were applied to LG H&H LIPCERIN products.

Correlations between the group velocity of time-reversed Lamb waves and cortical bone properties in tibial cortical bone in vivo (생체 내 경골의 피질골에서 시간역전 램파의 군속도와 피질골 특성 사이의 상관관계)

  • Kang Il Lee
    • The Journal of the Acoustical Society of Korea
    • /
    • v.42 no.6
    • /
    • pp.559-564
    • /
    • 2023
  • It is known that change in the bone strength of cortical bone constituting the outer shell of long bones such as the tibia or radius due to aging and osteoporosis is a risk factor for fracture. In this study, the group velocity of time-reversed Lamb waves generated in tibial cortical bone in vivo was measured using a time reversal method, and the correlations of the group velocity with the cortical bone thickness (cTh) and cortical bone mineral density (cBMD) closely related to the bone strength were investigated. It was found that the group velocity of time-reversed Lamb waves measured in the right tibia of 7 subjects showed a very high correlation, r = 0.90 (p < 0.0001), with the cTh and a relatively low correlation, r = 0.69 (p < 0.0001), with the cBMD. A limitation of this in vivo study is that the group velocity of time-reversed Lamb waves was measured for a normal group consisting of only 7 healthy adults. In the future, if the clinical usefulness of the time-reversed Lamb wave is demonstrated by follow-up studies on normal and osteoporotic groups consisting of a large number of healthy adults and osteoporotic patients, respectively, it is expected to improve the reliability of quantitative ultrasound technology for osteoporosis diagnosis. In addition, it is necessary to expand the skeletal site for measuring the group velocity of time-reversed Lamb waves not only to the tibia but also to the femur or radius.

The Effects of Case-Based Learning (CBL) on Problem Solving Ability and Academic Self-efficacy in Nursing Students (사례기반학습을 적용한 수업이 간호대학생의 문제해결능력과 학업적 자기효능감에 미치는 효과)

  • Jin Hye Kyung;Yun Mi Jin
    • The Journal of the Convergence on Culture Technology
    • /
    • v.9 no.6
    • /
    • pp.1143-1149
    • /
    • 2023
  • The purpose of this study was to the effects of case-based learning (CBL) on problem solving ability and academic self-efficacy in nursing students and was a quasi-experimental study with a one-group pretest-posttest design. The subjects of this study were 121 grade 4 students, and the data collection period was from Aprill 24 to June 12, 2023. The research procedure was scenario development, preliminary investigation, application of case-based learning classes, and follow-up investigation, and the CBL was conducted for 2 weeks, 50 minutes per week. The general characteristics of the subjects were obtained by frequency, percentage, mean, and standard deviation and the effects of CBL on problem solving ability and academic self-efficacy was tested using a paired t-test. The results of this study showed that nursing students' problem solving ability (t=-5.70, p<.001) and academic self-efficacy (t=-3.25, p<.002) improved after applying CBL compared to before applying it. We suggest the use of case-based learning as a strategy to improve problem-solving skills and academic self-efficacy in nursing education. In the future, follow-up research is needed to verify the effectiveness by developing and applying step-by-step clinical cases at an appropriate level according to the learning content of nursing major subjects by grade.

Study of the Derive of Core Habitats for Kirengeshoma koreana Nakai Using HSI and MaxEnt (HSI와 MaxEnt를 통한 나도승마 핵심서식지 발굴 연구)

  • Sun-Ryoung Kim;Rae-Ha Jang;Jae-Hwa Tho;Min-Han Kim;Seung-Woon Choi;Young-Jun Yoon
    • Korean Journal of Environment and Ecology
    • /
    • v.37 no.6
    • /
    • pp.450-463
    • /
    • 2023
  • The objective of this study is to derive the core habitat of the Kirengeshoma koreana Nakai utilizing Habitat Suitability Index (HSI) and Maximum Entropy (MaxEnt) models. Expert-based models have been criticized for their subjective criteria, while statistical models face difficulties in on-site validation and integration of expert opinions. To address these limitations, both models were employed, and their outcomes were overlaid to derive the core habitat. Five variables were identified through a comprehensive literature review and spatial analysis based on appearance coordinates. The environmental variables encompass vegetation zone, forest type, crown density, annual precipitation, and effective soil depth. Through surveys involving six experts, importance rankings and SI (Suitability Index) scores were established for each variable, subsequently facilitating the creation of an HSI map. Using the same variables, the MaxEnt model was also executed, resulting in a corresponding map, which was merged to construct the definitive core habitat map. Out of 16 observed locations of K. koreana, 15 were situated within the identified core habitat. Furthermore, an area historically known to host K. koreana but not verified in the present, Mt. Yeongchwi, was found to lack a core habitat. These findings suggest that the developed models exhibit a high degree of accuracy and effectively reflect the current ecological landscape.

Imaging Findings of Peripheral Arterial Disease on Lower-Extremity CT Angiography Using a Virtual Monoenergetic Imaging Algorithm (가상의 단일 에너지 영상 재구성 기법을 이용한 하지 단층촬영 혈관조영술에서 말초 동맥 질환 영상 소견)

  • Jun Seong Kim;So Hyun Park;Suyoung Park;Jung Han Hwang;Jeong Ho Kim;Seong Yong Pak;Kihyun Lee;Bernhard Schmidt
    • Journal of the Korean Society of Radiology
    • /
    • v.83 no.5
    • /
    • pp.1032-1045
    • /
    • 2022
  • Peripheral arterial disease (PAD) is common in elderly patients. Lower-extremity CT angiography (LE-CTA) can be useful for detecting PAD and planning its treatment. PAD can also be accurately evaluated on reconstructed monoenergetic images (MEIs) from low kiloelectron volt (keV) to high keV images using dual-energy CT. Low keV images generally provide higher contrast than high keV images but also feature more severe image noise. The noise-reduced virtual MEI reconstruction algorithm, called the Mono+ technique, was recently introduced to overcome such image noise. Therefore, this pictorial review aimed to present the imaging findings of PAD on LE-CTA and compare low and high keV images with those subjected to the Mono+ technique. We found that, in many cases, the overall and segmental image qualities were better and metal artifacts and venous contamination were decreased in the high keV images.

Mediastinal Lymph Node Metastasis from Head and Neck Cancer: Predictive Factors and Imaging Features (두경부암의 종격동 림프절 전이: 예측인자 및 영상 소견)

  • Il Kwon Ko;Dae Young Yoon;Sora Baek;Ji Hyun Hong;Eun Joo Yun;In Jae Lee
    • Journal of the Korean Society of Radiology
    • /
    • v.82 no.5
    • /
    • pp.1246-1257
    • /
    • 2021
  • Purpose To assess the predictive factors and describe the imaging features of mediastinal lymph node (MLN) metastases in patients with head and neck cancer. Materials and Methods We compared the clinical features and disease characteristics (sex, age, site of primary tumor, histologic type, history of prior treatments, TNM stages, and metastasis in cervical LNs) of patients with head and neck cancers between the MLN metastasis and no MLN metastasis groups. We also evaluated the chest CT (distribution and maximum dimension of the largest LN) and PET/CT (maximum standardized uptake value) features of MLN metastases based on the MLN classification. Results Of the 470 patients with head and neck cancer, 55 (11.7%) had MLN metastasis, involving 150 mediastinal stations. Hypopharynx cancer, recurrent tumor, T4 stage, N2/N3 stages, and M1 stage were found to be significant predicting factors for MLN metastasis. The most common location of MLN metastasis was ipsilateral station 2 (upper paratracheal LNs, 36.4%), followed by ipsilateral station 11 (interlobar LNs, 27.3%) and ipsilateral station 10 (hilar LNs, 25.5%). Conclusion Metastasis to MLNs should be considered in patients with head and neck cancer, especially in cases that are associated with a hypopharyngeal cancer, recurrent tumor, and high TNM stages.