• Title/Summary/Keyword: 임상지표

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Lifelog Big Data Based Metabolic Syndrome Management System (라이프로그 빅데이터 기반 대사증후군 관리 시스템)

  • Kim, Ji-Eon;Kim, Seung-Jin;No, Si-Hyeong;Jeong, Chang-Won;Kim, Tae-Hoon;Jun, Hong-Yong;Yu, Tae-Yang;Yoon, Kwon-Ha
    • Proceedings of the Korea Information Processing Society Conference
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    • 2018.05a
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    • pp.236-237
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    • 2018
  • 최근 생활습관정보는 대사증후군을 진단하기 위한 임상적 진단지표로 중요하게 활용되고 있다. 대사증후군은 심혈관 및 간질환 그리고 당뇨와 같은 여러 합병증을 유발할 수 있는 질환으로 질환 정도에 따른 체계적 관리가 필요하다. 그러나 대사증후군 환자의 생활습관을 수집하기 위한 대부분의 시스템은 자가진단 및 예방 중심의 시스템으로 구성되어 있어 정확한 생활습관을 수집하여 생활습관을 관리하기에는 어려움이 있다. 본 논문에서 제안하는 시스템은 임상적 진단지표에 도움이 될 수 있도록 신뢰성 있는 생활습관 정보를 수집하기 위한 방법을 제시하고 수집된 생활습관정보를 모니터링 하여 환자의 생활습관 개선 여부에 따라 지속적인 피드백을 제공하여 체계적으로 생활습관을 관리할 수 있는 시스템을 제안하고자 한다.

Comparative evaluation of the effects of oil pulling on periodontal indices - Using generalized estimating equation model (오일 풀링 중재에 따른 치주질환 임상 지표 비교 -일반화추정 방정식 모형의 적용)

  • Kim, Yun-Jeong;Yang, Jin-Ju;Lee, Mi-Ra;Kim, Mi-Hye;Youn, Geum-Chae;Lee, Ga-Yeon
    • Journal of Korean society of Dental Hygiene
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    • v.20 no.6
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    • pp.973-980
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    • 2020
  • Objectives: This study was to analyz the effects of comparative evaluation of the effects of oil pulling on periodontal indices. Methods: A total subjects were 38; control group (19 subjects) and experimental group (19 subjects). In the experimental group, coconut oil was provided and rinsed the mouth for about 10 minutes once a day. We evaluated possession rate of pocket depth (≥4 mm), possession rate of bleeding on exploring and possession rate of gingival recession (≥1 mm). Results: The possession rate of pocket depth (≥4 mm), bleeding on exploring and gingival recession (≥1 mm) significant difference in interaction between the group and measurement time. Conclusions: The findings of this study indicate that dental hygiene process and oil pulling specialists in care of periodontal diseases were effective mediation.

The Assessment of Blood Glucose Distribution according to the Fasting State and Glycemic Control Indicators for Diabetes Screening (금식 여부에 따른 혈당치 분포와 당뇨병 선별을 위한 혈당조절지표의 평가)

  • Kwon, Pil Seung;Rheem, Insoo
    • Korean Journal of Clinical Laboratory Science
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    • v.48 no.4
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    • pp.312-320
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    • 2016
  • This study analyzed the distribution of the blood glucose level according to the fasting status. Moreover, a relationship was analyzed between fasting blood glucose level and glycemic control indicators. A total of 707 outpatients, who visited Dankook University Hospital, were included and classified into either the fasting group and the non-fasting group. The mean blood glucose level of each group was calculated and analyzed by sex, age, and clinic. In addition, blood glucose, HbA1c, fructosamine, and 1,5-AG were measured in 153 fasting health check-up patients, and the correlation between the blood glucose level and glycemic control indicators was evaluated. Blood glucose averages between the two groups (non-fasting 111.9 vs. fasting 103.6 mg/dL) were different (p<0.05); and the mean difference was lower in women (4.8 mg/dL) than in men (12.2 mg/dL). A significant difference of the median glucose values among the age groups was only observed in the non-fasting group (Kruskal-Wallis test, p<0.01), and not in the fasting group. A 1,5-Anhydroglucitol was estimated to be significantly correlated with the fast blood glucose level in the range of the criteria of impaired fasting glucose (IFG). We presented an assessment of the distribution of blood glucose level in accordance with the fasting status among outpatients, and estimated that 1,5-anhydroglucitol was well correlated with the fasting blood glucose than fructosamine and HbA1c, through the analysis of results of health screening subjects. It is suggested that the use of glycemic indicators that reflect short-term blood glucose control can be used together with the blood glucose measurement in the screening of diabetes mellitus.

Effects of the Short-Term Weight Control Program on Periodontal Health in the University Students: A Pilot Study (일개 대학생의 단기 체중조절 프로그램이 치주건강에 미치는 영향: 사전연구)

  • Koong, Hwa-Soo;Son, Soo-Jung;Park, Hoo-Seob;Seo, Hyung-Seok;Hwang, Soo-Jeong
    • Journal of dental hygiene science
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    • v.15 no.4
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    • pp.413-418
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    • 2015
  • Recent cross-sectional studies indicate that obesity is a risk factor for periodontal disease. This study was aimed to investigate whether the four-week weight control program including caloric restriction and exercise training could have an effect on periodontal health. Forty-one obese (body mass index [BMI] ${\geq}25.0$) and five overweight ($23.0{\leq}BMI<25.0$) students participated in the weight control program. Anthropometric data and oral examination data were collected at the baseline and at the 27th day. BMI, waist hip ratio (WHR), and percent of body fat (PBF) of the subjects decreased significantly, but gingival index, sites with bleeding on probing (BOP), and sites with shallow pocket depth didn't show the significant changes in paired t-test. There was no difference in the outcomes according to smoking, drinking alcohol, and sex. Nevertheless, PBF and sites with BOP (r=0.777) and WHR and sites with shallow pocket depth (r=0.444) showed positive correlations. PBF accounted for 58.9% of the variance in sites of BOP in regression analysis. We suggested that obesity might relate with periodontal health, although it was not clear whether weight control could influence on periodontal health directly.

Relationship of the hs-CRP Levels with FBG, Fructosamine, and HbA1c in Non-diabetic Obesity Adults (당뇨병이 없는 비만 성인의 hs-CRP 수준과 FBG, Fructosamine 및 HbA1c와의 관련성)

  • Oh, Hye Jong;Choi, Cheol Won
    • Korean Journal of Clinical Laboratory Science
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    • v.50 no.2
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    • pp.190-196
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    • 2018
  • Obesity has been reported to be a cluster of risk factors in the pathological ecology, In particular, there is increasing evidence that inflammation-related factors are associated with diabetes. This study examined the relationship between the hs-CRP level and FBG, fructosamine, and $HbA_1c$ in 4,734 non-diabetic adults aged 20 years or older, who were approved by the National Health and Nutrition Survey in 2015. The results showed that the FBG, fructosamine, and $HbA_1c$ levels increased with increasing BMI; the hs-CRP levels were the highest in the obese group, and HOMA-IR, an index of insulin resistance, was also significantly higher in the obese group. The hs-CRP level was the highest in obese adults. The levels of FBG, fructosamine. and $HbA_1c$, which are involved in blood glucose control, increased with increasing hs-CRP level. The FBG, fructosamine, and $HbA_1c$ levels increased significantly with increasing hs-CRP level after adjusting for various related variables. These results suggest that the obesity-induced increase in hs-CRP is a risk factor for diabetes mellitus in non-diabetic adults. Therefore, proper dietary habits and regular exercise should prevent diabetes by preventing obesity in non-diabetic adults.

Medical bigdata-based Extended Artificial Intelligence Integration Platform (의료 빅데이터기반 확장 인공지능 통합플랫폼)

  • Lee, Chung-sub;Kim, Ji-Eon;Noh, Si-Hyeong;Kim, Tae-Hoon;Lee, Yun Oh;Yu, Yeong-Ju;Chun, JungBum;Jeong, Chang-Won
    • Proceedings of the Korea Information Processing Society Conference
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    • 2020.11a
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    • pp.45-46
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    • 2020
  • 최근 의료데이터의 표준화를 기반으로 다양한 임상연구가 국내외에서 활발하게 진행되고 있다. 그러나 대부분 개발기술이 임상현장에 적용되지 못하는 이유는 상이한 인프라로 인한 일관성있는 결가를 도출하지 못하는 문제점과 부족한 진단지표와 기준 그리고 충분하지 못한 기술적·임상적 검증이 문제가 되고 있다. 본 논문에서는 이러한 문제점을 해결하기위한 새로운 통합 플랫폼을 제안하고자 한다. 이를 위해서 임상데이터는 OHDSI의 OMOP-CDM으로 표준화되어야 하며, 이외에 의료영상 정보를 포함한다. 제안한 플랫폼은 표준화된 데이터를 통해 지속적인 자가 학습을 수행하며, 질환별 진단에 필요한 개발 도구와 분석 소프트웨어 도구를 통해 다양한 타겟 질환연구를 지원한다. 제안한 플랫폼은 질환에 대한 비침습적 진단을 위해 의료영상을 기반으로 데이터표준화을 기반으로하며, 이를통해 인공지능 기술을 개발하고 병원 정보시스템과 연계하여 임상현장에 실증을 통해 검증하고자 한다.

Comparison of Litter Production and Nutrient returned to Forest Floor according to Forest Fire Type and Recovery (산불유형과 회복정도에 따른 낙엽생산량과 임상으로 이입되는 영양염류 함량)

  • Kim, Jung-Sup;Yang, Keum-Chul
    • Korean Journal of Environment and Ecology
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    • v.26 no.1
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    • pp.67-73
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    • 2012
  • This study has compared the different types of forest fire sites and the unburned site at Samcheuk-si Gangwon-do by assessing the amount of litter production, nutrient concentration returned to forest floor from July 2007 through October 2010. The research showed that the average amounts of litterfall produced in the unburned site, the crown fire site(C-1), the crown fire site(C-3) and the ground fire site(G-2) were $7.74{\pm}2.56$, $1.17{\pm}0.67$, $2.97{\pm}0.44$ and $2.92{\pm}0.42ton{\cdot}ha^{-1}{\cdot}yr^{-1}$, respectively. In the unburned site, the average amounts of total nitogen(T-N), total phosphorus(T-P), potassium(K), calcium(Ca) and magnesium(Mg) returned to the forest floor were $22.20{\pm}12.43$, $1.16{\pm}0.46$, $2.68{\pm}1.44$, $16.22{\pm}4.69$ and $1.36{\pm}0.32 kg{\cdot}ha^{-1}{\cdot}yr^{-1}$, respectively whereas those in the crown fire site(C-1) were $3.73{\pm}2.31$, $0.10{\pm}0.09$, $0.27{\pm}0.20$, $2.75{\pm}2.58$ and $0.24{\pm}0.27 kg{\cdot}ha^{-1}{\cdot}yr^{-1}$, respectively. This study showed that the nutrient content returned to forest floor was higher in the following order: unburned site(Un) > crown fire site(C-3) > ground fire site(G-2) > crown fire site(C-1).

Maintenance of Platelet Counts with Low Level QC Materials and the Change in P-LCR according to Hemolysis with XN-9000 (XN-9000장비에서 Low Level QC물질에서의 혈소판 수 관리와 용혈에 따른 P-LCR의 변화)

  • Shim, Moon-Jung;Lee, Hyun-A
    • Korean Journal of Clinical Laboratory Science
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    • v.50 no.4
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    • pp.399-405
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    • 2018
  • The platelet count in clinical laboratories is essential for the diagnosis and treatment of hemostasis abnormalities, and accurate platelet counting in the low count range is of prime importance for deciding if a platelet transfusion is needed and for monitoring after chemotherapy. Quality control is designed to reduce and correct any deficiencies in the internal analytical process of a clinical laboratory prior to the release of patient results. Fragmented erythrocytes are the major confusing factors for platelet counting because of their similar size to platelets. The authors found that the low range QC values were out of 2SD with a Sysmex automatic analyzer in internal quality control process. Thus far, there has been little discussion on the relationship between hemolysis and the platelet parameters. Therefore, this study focused on the performance of automated platelet counts, including the PLT-F, the PLT-I, and PLT-O methods at the low platelet range using the low level QC materials and compared the 5 platelet parameters with the hemolyzed samples. The results showed that the CV was the smallest with PLT-F and P-LCR increased from 18.4 to 31.9% in the hemolysis samples. These results indicate that a more accurate estimation of the platelet counts can be achieved using the PLT-F method than the PLT-I method at the low platelet range. The use of the PLT-F system improves the confidence of results in low platelets samples in a routine hematology laboratory. The results suggest that P-LCR is a new parameter in assessing samples when the specimen is suspected of hemolysis and deterioration. Nevertheless, further studies will be needed to establish the relationship with P-LCR and hemolysis using human blood specimens.

An Action Convergence Research to Improve Evaluation Index of Pneumonia Adequacy in Regional Public Hospital (지역거점 공공병원의 폐렴 적정성 평가 지표 개선을 위한 융복합 실행연구)

  • Eun Young Choi;Yoen-Im Park;Seung-Ju, Kang;Ja-Ok Kim
    • Journal of Digital Convergence
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    • v.21 no.1
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    • pp.19-27
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    • 2023
  • This is an implementation study towards the development of a strategy to improve the pneumonia adequacy evaluation index of regional public hospital and to confirm its effectiveness. One physician, eight nurses, one computer room staff, and one nursing professor working at a regional base public hospital located in N city participated in this study from March to October 2021. An implementation study was conducted based on the conceptual model of Zuber-Skerritt & Fletcher. The stages of planning, implementation, evaluation, and reflection were operated in two cycles, and the effectiveness was evaluated in the second and third quarters. Compared to the pneumonia adequacy evaluation index in 2019, all indicators reached 100% of the standard target in 2021. The results of this study therefore infer that to provide higher quality medical services in the future, it is necessary to apply medical quality improvement activities through practical research under multidisciplinary participation and cooperation and to review the applicability of clinical sites.

Safety Assessment of Osmolality Concentration and Biochemical Factors Changes in Electrolyte Metabolism during an Ultra-marathon (100 km) (울트라 마라톤(100 km)에서 삼투압 농도와 전해질 대사의 생화학적 요인 변화에 대한 안전성 평가)

  • Shin, Kyung-A;Kim, Young-Joo
    • Korean Journal of Clinical Laboratory Science
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    • v.48 no.2
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    • pp.137-143
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    • 2016
  • This study was conducted to investigate the electrolyte metabolic responses to a 100 km ultra-marathon in 22 male amateur runners. Their average age was $50.91{\pm}4.77$ years old and their $VO_2max$ value was $48.19{\pm}6.4 mL/kg/min$. The participants completed the race with a mean finishing time of $205.55{\pm}19.61$ minute. Electrolyte parameters based on blood tests including calcium, inorganic phosphorus, magnesium, sodium, potassium, chloride, total carbon dioxide, anion gap, plasma volume change and osmolality were measured pre-race, at 50 km, and at 100 km (post-race). Only slight changes in sodium level with no cases of hypernatremia or hyponatremia were observed. Additionally, all the electrolyte parameters changes were within the normal range and plasma volumes were unchanged. Overall, amateur marathon runners are not at risk to develop clinically significant electrolyte or osmolality changes during a 100 km ultra-marathon.