• Title/Summary/Keyword: 임상적 접근

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Review of Lung Cancer Survival Analysis with Multimodal Data (다중 모드 데이터를 사용한 폐암 생존분석 검토)

  • Choi, Chul-woong;Kim, Hyeon-Ji;Shim, Eun-Seok;Im, A-yeon;Lee, Yun-Jun;Jeong, Seon-Ju;Kim, Kyung-baek
    • Proceedings of the Korea Information Processing Society Conference
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    • 2020.11a
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    • pp.784-787
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    • 2020
  • 폐암 환자의 생존율을 예측할 때 미국암연합회(AJCC)의 TNM병기 분류체계에 의해 진단되는 최종병기를 많이 사용한다. 최종병기는 폐암환자의 임상데이터 중 하나로 종양의 위치, 크기, 전이정도를 고려하여 환자의 폐암 상태를 판별하는 정보이다. 최종병기는 개략적인 환자의 상황을 설명하는 데 효과적이지만, 보다 구체적인 생존분석을 위해서는 임상데이터 뿐만 아니라 PET/CT와 같은 영상 데이터를 함께 분석해야 한다. 이 논문에서는 데이터 과학적 접근을 통해 폐암환자의 임상데이터, CT영상과 PET영상 등 다양한 종류의 데이터를 함께 활용하는 생존분석기법을 검토한다. 실험을 통해 다중 모드 데이터를 활용하는 생존분석을 위해 비선형모델 개발과 Feature임베딩 기법 고도화가 필요함을 확인하였다.

A Case of Sheehan's Syndrome Mimicking Psychotic Depression (정신병적 우울증 양상을 나타낸 Sheehan씨 증후군 1례)

  • Jeong, Jong-Hyun;Hong, Seung-Chul;Lee, Sung-Pil;Han, Jin-Hee
    • Korean Journal of Psychosomatic Medicine
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    • v.5 no.1
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    • pp.118-122
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    • 1997
  • We experienced a case of 51-year-old female patient who showed symptoms of persecutory delusion, auditory hallucination and hallucinatory behavior, severe insomnia, psychomotor retardation and social withdrawal, along with some clinical signs of the deficiency of various hormones those gradually progressed after massive postpartum vaginal bleeding 13 years ago. She was admitted to a psychiatric ward under the impression of psychotic depression. However careful history taking and evaluation of clinical feature gave rise to the possibility of underlying medical condition. Laboratory work-up revealed panhypopituitarism, hypoglycemia and hyponatremia. After replacement of thyroid hormone and cortisol for 1 week, her clinical symptoms including psychiatric symptoms were improved. Taken together, these findings were compatible with the diagnosis of Sheehan's syndrome. On reporting this case, we would like to emphasize again the importance of differential diagnosis of medical problems causing psychiatric symptoms those are easily neglected in the clinical approach toward psychiatric patients.

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What is the Potential of Animal Models to Inform Occupational Therapy Theories and Interventions From the Perspective of Neuroscience? (신경과학적 관점으로 본 작업치료에서 동물 모델의 필요성)

  • Park, Ji-Hyuk;Ahmad, S. Omar
    • Therapeutic Science for Rehabilitation
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    • v.1 no.1
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    • pp.39-56
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    • 2012
  • Introduction : Animal studies cannot be applied directly to Occupational Therapy(OT) intervention protocol. However, animal models still provide essential evidences and knowledge to improve OT practice and to develop OT theories as well as human studies do. The purpose of this scholarly paper is to explore the potential of animal models to inform OT theory and practice particularly as it relates to neuroscience. Body : The animal models provide related knowledge for a better understanding of the mechanism of diseases and related neural networks. Based on this knowledge, researchers can test their hypothesis of neural disease. In addition, accumulated animal studies contribute to introduce the new approaches to human diseases and to improve the effectiveness of treatment. Conclusions : Animal models of neurological disease are critical and have the potential to improve OT practice and theory in many ways. Therefore, OT researchers need to pay more attention to animal models in addition human studies.

Functional Anatomy and Biomechanics of the Patellofemoral Joint (슬개대퇴 관절의 기능적 해부학 및 생체역학)

  • Kim, Hyoung-Soo;Park, Sang-Joon
    • Journal of Korean Orthopaedic Sports Medicine
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    • v.4 no.2
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    • pp.74-78
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    • 2005
  • Even though, anterior knee pains are most frequently encountered in knee clinics, many physicians use a 'recipe'-type of approach to their treatment. But many predisposing factors have been included internal rotation of the femur, valgus knee alignment, external rotation of the extensor mechanism, patellar alta, a flat trochlear groove, patella with poor congruence and ligatmentous laxity. Many scientific principles on which these commonly used treatment are based, can lead to refinements and improvement in treatment. We reviewed and summarized the recent functional anatomical and biomechanical data that are most relevant to the contemporary treatment of patellofemoral joint disorders.

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FUNCTIONAL RECONSTRUCTION OF MANDIBULAR DEFECTS WITH FREE BONE GRAFT (유리골 이식을 통한 하악골 결손부의 기능적 재건술)

  • Kim, Jong-Won;Nam, II-Woo;Kim, Myung-Jin;Choung, Pill-Hoon;Seo, Byung-Moo;You, Jun-Young;Nam, Ki-Weon;Song, Min-Seok
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.15 no.4
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    • pp.338-345
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    • 1993
  • Mandibular discontinuity defect due to benign tumor, malignant tumor, infection, or truma results in major esthetic and biologic compromise. The primary goal of reconstruction is full restitution of function, which secondarily lead to normalization of the cosmetic deformity. The authors make a clinical study of 61 consecutive bone graft cases for mandibular reconstruction of discontinuity defect which were studied retrospectively using clinical data and radiographic findings. The cases were reviewed to evaluate the clinical success in the period from 1981 to 1990 in the Dept. of Oral & maxillofacial Surgery, Seoul National University Hospital. The criteria of the success in bone graft, are no residual infection, graft in with maintain its integrity, and remain over a half of its original size of graft in the radiographic features. The purpose of this clinical survey is to study of the mandibular discontinuity defects and success rate of free bone graft in mandibular defects. To summarize the clinical study of free bone graft, the main type of autogenous bone graft is iliac bone and corticocancellous type. Overall success rate is 80.3% in 61 followup cases over 6 months. Wire fixation and Extraoral approach has realtively better prognosis than other methods. It showed relatively poor prognosis in symphysis defects than other recipient site.

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A Clinical Study on Fiberoptic Bronchoscopy (화이버 기관지경 검사의 임상적 고찰)

  • 이상기;홍영호;권평중;김중환
    • Proceedings of the KOR-BRONCHOESO Conference
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    • 1981.05a
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    • pp.3.2-3
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    • 1981
  • This paper was attemped to analize 55 cases of fiberoptic bronchoscopy during period of 3 years from Feb. 1978 till Feb. 1981 in Chung Ang University hospital. The results were as follow; 1) In age distribution; Most common age group was 5th decade (15 cases, 27.2%) and the other age groups showed relatively even distribution. 2) The ratio of male to female was 3 to 1. 3) The chief complaints were presented in following order; cough (52%), hemoptysis(25%), dyspnea(23.6%), chest pain(18%), chest disomfort(9%). 4) Direct smear of bronchoscopic aspiration material; Not found 33 cases (60%) were most common finding. In the founded bacteria Gram positive cocci 2 cases (3.6%), Gram negative cocci 2 cases (3.6%), Gram positive bacilli 1 cases (1.8%), Gram negativebacilli 2 cases (3.6%), mixed form 15 cases(27.2%) were presented. 5) Bacterial culture of bronchoscopic aspiration material; No growth 28 cases (50.9%) were most common finding. In the bacterial growth, alpha hemolytic streptococci 10 cases (18.2%), Neisseria group 7cases(12.7%), Klebsiella 2 cases (3.6%), Pseudomonas 2 cases (3.6%), mixed culture 6 cases (10.9%) were presented, 6) The diagnosis of bronchoscopic appearance, laboratory exam., and pathologic exam. of biopsed specimen were 21 cases (38.1%) primary carcinoma of bronchus, 8 cases (14.5%) pulmonary tuberculosis, 7 cases (12.7%) bronchitis in orders.

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Database Security System supporting Access Control for Various Sizes of Data Groups (다양한 크기의 데이터 그룹에 대한 접근 제어를 지원하는 데이터베이스 보안 시스템)

  • Jeong, Min-A;Kim, Jung-Ja;Won, Yong-Gwan;Bae, Suk-Chan
    • The KIPS Transactions:PartD
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    • v.10D no.7
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    • pp.1149-1154
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    • 2003
  • Due to various requirements for the user access control to large databases in the hospitals and the banks, database security has been emphasized. There are many security models for database systems using wide variety of policy-based access control methods. However, they are not functionally enough to meet the requirements for the complicated and various types of access control. In this paper, we propose a database security system that can individually control user access to data groups of various sites and is suitable for the situation where the user's access privilege to arbitrary data is changed frequently. Data group(s) in different sixes d is defined by the table name(s), attribute(s) and/or record key(s), and the access privilege is defined by security levels, roles and polices. The proposed system operates in two phases. The first phase is composed of a modified MAC (Mandatory Access Control) model and RBAC (Role-Based Access Control) model. A user can access any data that has lower or equal security levels, and that is accessible by the roles to which the user is assigned. All types of access mode are controlled in this phase. In the second phase, a modified DAC(Discretionary Access Control) model is applied to re-control the 'read' mode by filtering out the non-accessible data from the result obtained at the first phase. For this purpose, we also defined the user group s that can be characterized by security levels, roles or any partition of users. The policies represented in the form of Block(s, d, r) were also defined and used to control access to any data or data group(s) that is not permitted in 'read ' mode. With this proposed security system, more complicated 'read' access to various data sizes for individual users can be flexibly controlled, while other access mode can be controlled as usual. An implementation example for a database system that manages specimen and clinical information is presented.

Permanent Transvenous Cardiac Pacing in a Beagle Dog With a Third Degree Atrioventricular Block (경피적 접근을 이용한 영구 박동조절기(pacemaker) 장착을 통한 3도 방실 차단이 있는 비글종 개의 치료)

  • Lee, Seung-Gon;Moon, Hyeong-Sun;Lee, Moo-Hyun;Hyun, Chang-Baig
    • Journal of Veterinary Clinics
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    • v.24 no.3
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    • pp.414-418
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    • 2007
  • A 2.8-year-old intact female Beagle dog (weighing 11kg) was referred with the primary complaint of exercise intolerance with occasional syncope. Physical examination revealed irregularly irregular heart rhythm with persistent pulse deficits. The 12-lead surface ECG showed a third degree heart block. Permanent transvenous cardiac pacing with a bipolar implantable pacemaker was performed in the right ventricle. After pacemaker implantation, the dog did not show syncopal episode and is currently able to take a walk with an owner. No side effects associated with permanent pacemaker implantation has been observed to date.

Effects of Cosmetics containing Pycnogenol on the skin of Korean Women in their 40s and 50s - Skin Clinical Approach (피크노제놀을 함유한 화장품이 40~50대 한국 여성의 피부에 미치는 영향 - 피부임상학적 접근)

  • Kim, Kyung-Yun;Ku, Jung-Eun
    • Journal of the Korea Convergence Society
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    • v.12 no.8
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    • pp.309-315
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    • 2021
  • Pycnogenol extracted from pine bark is a component with great antibacterial activity and antioxidant effect. It is applied as a natural anti-inflammatory agent with various medical effects including anti-inflammatory effects, regulation of blood pressure, regulation of the immune system, and inhibition of cancer cell growth. However, research related to cosmetics is limited. Therefore, in this study, the effect of Pycnogenol on the skin was studied through a clinical approach. Changes in skin condition were observed after using cosmetics with Pycnogenol and without Pycnogenol for 6 weeks for 10 clinicians in each group. We observed the effect of pore reduction, wrinkle reduction around eyes, a decrease of the number and angle of loose pores, and reduction of pigmentation. Therefore, cosmetics containing Pycnogenol have the effect of improving skin problems of aging skin.

Practical Approach for the Clinical Use of Dopamine Transporter Imaging (도파민 운반체 영상의 임상이용을 위한 실제적 접근)

  • Kim, Jae-Seung
    • Nuclear Medicine and Molecular Imaging
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    • v.42 no.6
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    • pp.425-434
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    • 2008
  • Dopamine transporter imaging is useful in the diagnosis of Parkinson's disease and the most successful technique in the clinical use of neuroreceptor imaging. Recently, several radiopharmaceuticals including I-123 FP-CIT, Tc-99m TRODAT, and F-18 FP-CIT for dopamine transporter imaging have been approved for the routine clinical use in several European countries, Taiwan and Korea, respectively. This review summarized the practical issue for the routine clinical examination of dopamine transporter imaging.