• Journal of the Korean Society of Radiology
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• v.83 no.1
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• pp.42-53
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• 2022

The clinical concept of coronary artery disease (CAD) has seen a paradigm shift over the last decade. CAD is mostly a progressive disease, and patients with CAD can develop acute coronary syndromes at any point in disease progression. In this clinical context, a new term, "chronic coronary syndrome," was published in the 2019 European Society of Cardiology guidelines, reflecting the importance of early diagnosis and active management. Recent advances have been made in the evaluation of CAD using coronary CT angiography (CCTA). The clinical usefulness of CCTA in patients with stable angina or chronic coronary syndrome begins with the detection of early asymptomatic CAD. The characterization of atherosclerotic plaque and its role in determining treatment strategies for CAD have been demonstrated for all stages of the disease. This review describes the pathophysiology of stable angina to aid in the understanding of the clinical applications of CCTA.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.8 no.1
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• pp.92-100
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• 1997

Objective：The objective of this study is to examine the clinical characteristics and behavioral comorbidity of patients with Tourette’s disorder. Method：Subjects consisted of 157 patients with Tourette’ disorder diagnosed by DSM-IIIR, who were examined and diagnosed from Jan. 1988 to May 1994 at the Tourette’s Clinic of Yonsei University Medical Center. Characteristics and behavioral comorbidity of Patients were assessed by a semi-structured interview schedule. Behavioral problems like hyperactivity, obsession-compulsion, self destructiveness, enuresis, sleep problem were assessed by global clinical impression. Results：The mean age of patients was 14.49(${\pm}7.99$) years. Patients consisted of 138 males (87.9%) and 19 females(12.1%). The sex ratio was 7：1, showing a male preponderance. The number of right-handers was 133(84.7%), and the number of non-right handers was 24(15.3%). Mean age of onset was 8.85(${\pm}4.56$) years, ranging from 2-to-16 years. More than half of the patients had their age of onset at 6-10 years. Bimodal peak in age of onset was observed；the first peak was around 6 and the second peak was around 10 years. There was no sex difference in bimodal age of onset. The most common initial symptom was eye blinking. More than 55% of patients reported eye blinking as their first symptom. The second common initial symptom was head turning and the third was vocal tic. The most common symptoms that patients reported on their first visit since onset were eye blinking(82.2%), head turning or nodding(57.9%), shoulder shrugging(52.7%) and forearm movement(32.6%). Of 157 cases, 101(64.3%) patients showed downward progression of symptoms, and 25(15.9%) showed upward progression of symptoms. Nineteen fathers(12%) of patients had a past history of obsessive-compulsive disorder(OCD). Seventeen fathers(10.6%) had a history of tic disorder. SSevenmothers(4.5%) had OCD, 4 mothers (2.5%) had tic disorder. One hundred and eighteen patients(75.1%) had comorbid hyperactivity, 95 patients(60.5%) had obsession, 55 patiens(35.0%) had self destructiveness, 46 patients(29.3%) had impulsivity, and 35 patients(22.3%) had enuresis. Age of onset had a significant positive correlation with age, duration, and the global severity of obsession；and a negative correlation with the severity of hyperactivity. Hyperactivity had a significant positive correlation with impulsivity, obsession-compulsion, enuresis, and self destructiveness. Obsession-compulsion had a significant positive correlation with hyperactivity, sleep problems, and self destructiveness. Conclusion：These data suggest that clinical characteristcs and behavioral comorbidity of patients with Tourette’ disorder in this study are similar to previous research findings in Korea and other contries. The younger the age of onset was, the more severe hyperactivity was, and the less severe obsession-compulsion was. And severity of hyperactivity had a positive correlation with the severity of obsession-compulsion, impulsivity, enuresis, and self destructiveness.

• 한국임상약학회:학술대회논문집
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• 2007.12a
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• pp.183-183
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• 2007

• 건강소식
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• v.7 no.2 s.51
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• pp.10-12
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• 1983

이번호부터 새로 연재되는 의학상식 시리즈는 세계적 권위기관인 국제임상세포학회 평의원이며 미국임상병리학회 평의원인 이인성 박사가 집필해 주시기로 되었습니다. 이 박사는 또한 건협에서 실시하고 있는 자궁암검진사업의 판독을 담당하고 있는 권위자 입니다.

• 대한족부족관절학회:학술대회논문집
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• 2008.11a
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• pp.22-23
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• 2008

• 대한치주과학회:학술대회논문집
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• 2004.11a
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• pp.161-161
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• 2004

• Proceedings of the KTCVS Conference
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• 1995.10a
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• pp.15-15
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• 1995

• 건강소식
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• v.7 no.3 s.52
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• pp.9-12
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• 1983

지난 호부터 새로 연재되는 의학상식 시리즈는 세계적 권위기관인 국제임상세포학회 평의원이며 미국임상병리학회 평의원인 이인성 박사가 집필해 주시기로 되었습니다. 이 박사는 또한 건협에서 실시하고 있는 자궁암검진사업의 판독을 담당하고 있는 권위자 입니다.

• Clinical and Experimental Pediatrics
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• v.46 no.4
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• pp.351-357
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• 2003

Purpose : To raise awareness of the clinical importance of, and the need for proper management of acute focal bacterial nephritis(AFBN), we analyzed 22 AFBN patients and 22 other upper urinary tract infection patients by use of comparative studies. Methods : From January 2000 to May 2002, 22 AFBN patients aged from 1 month to 12 months were selected. As a control group, 22 UTI patients with no radiologic abnormalities were selected and matched by age and sex. Results : The incidence of AFBN was more common in boys than in girls. Since both groups had similar symptoms, it was difficult to diagnose AFBN by clinical presentations alone. ESR and CRP were significantly higher in AFBN patients. The most common causative organism was E. coli in both groups. On the sonographic findings, the most lesions were seen on the upper lobe of the kidney; more frequently, on left kidney. The lesions showed globular or wedge-shaped increased echogenecity. $^{99m}Tc-DMSA$ scan showed the complete coincidence of the location, size and shape in all cases compared to the findings of renal sonography. Conclusion : The roles of renal sonography and DMSA scan were very important, and ultrasonography was an excellent initial tool in diagnosing AFBN. Since the degree of infection in AFBN is more severe than other urinary tract infections and evollution into a renal abscess is possible, early diagnosis and appropriate antibiotics therapy is essential.

• Journal of dental hygiene science
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• v.14 no.3
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• pp.349-355
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• 2014

The purpose of this study was to evaluate marginal gap of fixed dental prostheses (FDPs) fabricated by soft metal material with using dental computer aided design/computer aided manufacturing (CAD/CAM) system and to compare gap of its by a conventional method. Ten same cases of study models were manufactured and scanned for digital models fabricating. Ten FDPs were fabricated by soft metal material using dental CAD/CAM (SMB group). Then, ten FDPs were fabricated by cast metal using lost wax technique and casting method (LWC group). Marginal gap was measured by silicone replica technique. Gap was measured by digital microscope (${\times}160$). Mann-Whitney test for statistical analysis was executed (${\alpha}=0.05$). The mean (standard deviations) of marginal gap was $76.5{\mu}m$ (35.2) for the SMB group, and $82.9{\mu}m$ (22.1) for the LWC group. Statistically significant differences were not found between SMB and LWC. As results, FDPs fabricated by soft metal material were clinically acceptable range.