• Title/Summary/Keyword: 일일 소변 배설률

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Measurement of Uptake Rates of Internal Organs Including Thyroid Gland and Daily Urinary Excretion Rates for Adult Korean Males (한국남자 성인을 대상으로 한 방사성옥소($^{131}I$)의 갑상선 및 각 장기별 잔류율과 소변 일일배설률 측정)

  • Kim, Jung-Hoon;Kim, Hee-Geun;Whang, Joo-Ho
    • Journal of Radiation Protection and Research
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    • v.32 no.2
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    • pp.45-50
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    • 2007
  • In this study, uptake rates of internal organs and daily urinary excretion rates were measured to get more reliable estimation results for Korean. Radioactive iodine($^{131}I$) of $100{\mu}Ci$ was administered by ingestion to 28 adult males for the experiment and then the radioactivity in thyroid gland, liver, stomach, small intestine, kidneys, and urine was measured after time intervals of 2, 4, 6 and 24 hours. Uptake rates of each organ and daily urinary excretion rates were calculated on the basis of these experimental results. As a result, uptake rates of 19.70% for thyroid and daily urinary excretion rates of 71.12%, on the average, were indicated. The maximum of uptake rates and daily urinary excretion rates were recorded after 2 hours of administration of $^{131}I$, but those rates were decreased gradually later. It was also found that uptake rates were the highest in stomach, followed by the left kidney, liver, small intestine and right kidney except for thyroid gland. In this experiment, the calculated uptake change rate in thyroid gland after 24 hours of administration of $^{131}I$ was different from that of ICRP-54/67(30%) and ICRP-78(25%). Thus, it is necessary to apply more reliable approach, reflecting the characteristic of Korean physiology and to obtain the basic data of results using this approach for calculation of the internal adsorbed dose. In the future, this approach can be helpful for the internal dose assessment of radiation workers in a nuclear power plant or in a hospital.

Influence of the Statistical Distribution of Bioassay Measurement Errors on the Intake Estimation (바이오어쎄이 측정오차의 통계적 분포가 섭취량 추정판에 미치는 영향)

  • Lee, T.Y.;Kim, J.K.
    • Journal of Radiation Protection and Research
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    • v.31 no.1
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    • pp.17-23
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    • 2006
  • The purpose of this study is to provide the guidance necessary for making a selection of error distributions by analyzing influence of statistical distribution for a type of bioassay measurement error on the intake estimation. For this purpose, intakes were estimated using maximum likelihood method for cases that error distributions are normal and lognormal, and comparisons between two distributions for the estimated intakes were made. According to the results of this study, in case that measurement results for lung retention are somewhat greater than the limit of detection it appeared that distribution types have negligible influence on the results. Whereas in case of measurement results for the daily excretion rate, the results obtained from assumption of a lognormal distribution were 10 % higher than those obtained from assumption of a normal distribution. In view of these facts, in case where uncertainty component is governed by counting statistics it is considered that distribution type have no influence on intake estimation. Whereas in case where the others are predominant, it is concluded that it is clearly desirable to estimate the intake assuming a lognormal distribution.

Assessment of Absorbed Dose of by Organ according to Thyroidal Uptake of Radioactive Iodine for Adult Korean Males (한국성인 남성을 대상으로 한 방사성옥소의 갑상선 섭취율에 따른 각 장기별 흡수선량 평가)

  • Kim, Junghoon;Lim, Changseon;Whang, Jooho
    • Progress in Medical Physics
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    • v.18 no.4
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    • pp.187-193
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    • 2007
  • In an effort to assess the internal absorbed dose of radionuclides that is suitable to Koreans' physiological characteristics, we asked 28 male Koreans to take $^{131}|$ orally, determined the thyroidal uptake and daily urination ratio, and assessed the absorbed dose by organ. As a result, first, 24 hours after administering, the average thyroidal uptake and the daily urination ratio registered 19.70% and 71.12%, respectively. Second, the whole body effective dose according to the thyroidal uptake calculated herein and the existing ICRP-suggested thyroidal uptake of 30% offered 1.464E-08 Sv and 2.189E-08 Sv, respectively, showing a 1.5 times difference. To evaluate the quantity of the absorbed dose of radioactive iodine, we can better reduce the error in assessing the body exposure dose by conducting measurement according to human races rather than depending on the existing ICRP data.

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