• Proceedings of the Korea Institute of Fire Science and Engineering Conference
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• 2010.10a
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• pp.190-194
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• 2010

화재감지기는 화재시 발생되는 열, 연기, 불꽃, 독성가스등의 다양한 연소생성물을 감시한다. 기술의 발전으로 화재 감지방식과 기능이 다양해지고 있으며, 이에 따라 다양한 방식의 감지기들이 개발되고 있다. 최근 진보된 감지기들은 화재로 발생 이전에서 부터 감지, 비화재보에 대한 방지는 물론 감지기의 상태 오염 감도 등의 다양 정보를 제공함으로써 유사시 신속하고 정확한 대응이 가능하도록 발전되고 있다. 이러한 진보된 감지기는 막대한 피해가 예상되는 장소, 대피하는데 많은 시간이 소요되는 장소에 적용되어 인명 및 재산피해를 절감 시키고 있다. 일산화탄소감지기 또한 진보된 감지기로 화재 초기 가연물이 연소할 때 발생하는 일산화탄소를 감시한다. 일반화재의 경우 화재 초기에 가연물이 서서히 연소시 불완전 연소로 인한 다량의 일산화탄소가 발생되기 때문에 기존 열, 연기, 불꽃감지기에 비해 빠른 반응을 보여 화재를 조기에 감지함으로써 조기 대응으로 인한 피해를 줄일 수 있을 것이다. 본 연구에서는 실물화재시험 자료를 바탕으로 CO감지기의 조기 감시능력을 확인하였다. CO감지기는 화재초기 발생되는 일산화탄소를 감지하므로 대피시간이 많이 필요한 장소(병원 노인요양시설 학교 백화점 등), 침대 폼메트리스 훈소화재 발생장소(호텔침실 기숙사 숙박업소, 병실 등)등에 적응성이 우수할 것으로 분석된다. 최근 설계되는 초고층 건축물 및 주요 시설물 등에서 화재 시뮬레이션과 가상시나리오 유형 분석을 통해 성능위주의 설계가 적용되고 있다. 그만큼 정확하고 신속한 감지가 중요하다 할 수 있다. CO감지기야 말로 그 기대에 가장 부합될 것으로 분석된다.

• Proceedings of the Korea Information Processing Society Conference
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• 2011.04a
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• pp.1074-1077
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• 2011

국내외 대규모 산업시설은 유해물질과 직 간접적으로 밀접하게 관련되어 유해물질 누출사고는 막대한 물적, 인적 피해를 발생시키며 누출물질, 저장시설, 대기 상태에 따라 유해물질 확산 속도 및 범위가 다르기 때문에 이를 예측하는 대기확산 시스템이 필요하다. 또한 기존의 대기확산 시스템은 산업시설 구조물 설계 단계에서 안전성을 확인하는 시뮬레이션용으로 사용되었기 때문에 누출사고 발생 시 즉각적인 처리와 대응이 어려우며 전문적 지식수준의 사용자 입력을 요구한다. 본 논문은 에너지 플랜트 환경의 특수성과 효율성을 고려하여 운영 중인 시설에 적용 가능한 대기확산 시스템 연구를 목적으로 한다. 이를 위하여 신속하고 효율적인 대기확산 모델을 선정 정의하고 융통성 있는 대기확산 시스템의 구성요소를 컴포넌트화하여 구현하였으며 사고 발생 시 빠르게 피해범위를 예측할 수 있는 실시간 대기확산 시스템 설계 방안을 제시하였다.

• Korean Journal of Food Science and Technology
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• v.41 no.3
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• pp.320-325
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• 2009

The present study was carried out to investigate the acute oral toxicity and anti-obesity effects of a diglyceride preparation containing conjugated linoleic acid (DG+CLA). To test its acute oral toxicity, the DG+CLA was injected into 30 rats (15 males and 15 females) at dosage of 2,000 mg/kg and 5,000 mg/kg. Mortality rates, clinical signs, and body weight changes were monitored for 14 days following administration. According to the results, the lethal dose ($LD_50$) of DG+CLA was determined as >5,000 mg/kg in both sexes. There were no significant changes in general conditions, clinical signs, body weight, and gross lesions between the vehicle control and DG+CLA groups. For the anti-obesity studies, obese Zucker rats were randomly divided into 4 groups and fed saline, soybean oil, diglyceride, and DG+CLA, respectively, for 8 weeks. The DG+CLA groups presented significant differences in body weight, food efficiency ratio, serum lipid levels, and fat weight. Overall, the results showed that the DG+CLA did not have acute oral toxicity and reduced body weight, serum lipid levels, and fat gain.

• Journal of the Korean Society of Food Science and Nutrition
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• v.36 no.8
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• pp.960-964
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• 2007

This study was performed to examine the toxicity of Psoralea corylifolia L. by the single-dose oral toxicity tests in rat and bacterial reverse mutation assay. In single-dose oral toxicity tests, 5 mL ethanol extract of P. corylifolia L. were directly injected into 10 rats (5 males and 5 females) at a dosage of 2 g/kg. Death practice was not detected during breeding periods (14 days), and $LD_{50}$ was calculated over 2 g/kg. No difference were observed with control group in the growth rate and histological observations. In bacterial reverse mutation assay, his(-) Salmonella Typhimurium TA98, TA100, TA1535, TA1537 and trp(-) Escherichia coli WP2uvrA (pKM101) were used for assessing the toxicity of ethanol extracts of P. corylifolia L.. No significant difference in formation of the colonies and no dose-dependent increase was observed regardless of the addition of S9 mix. The results showed that ethanol extracts of P. corylifolia L. did not have single-dose oral toxicity and mutagenic toxicity.

• Journal of the Korean earth science society
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• v.44 no.6
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• pp.655-674
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• 2023

This study examined whether the "self-guided interpretation" media in the Yeoncheon area of the Hantangang River UNESCO Geopark are intelligible for visitors. Accordingly, two on-site investigations were conducted in the Hantangang River Global Geopark in September and November 2022. The Yeoncheon area, known for its diverse geological features and the era of geological attraction formation, was selected for analysis. We analyzed the readability levels, graphic characteristics, and alignment with science curriculum of the interpretive media specific to geological sites among a total of 36 self-guided interpretive media in the Yeoncheon area. Results indicated that information boards, primarily offering guidance on geological attractions, were the most prevalent type of interpretive media in the Yeoncheon area. The quantity of text in explanatory media surpassed that of a 12^th-grade science textbook. The average vocabulary grade was similar to that of 11^th- and 12^th-grade science textbooks, with somewhat reduced readability due to a high occurrence of complex sentences. Predominant graphic types included illustrative photographs, aiding comprehension of the geological formation process through multi-structure graphics. Regarding scientific terms used in the interpretive media, 86.3% of the terms were within the "Solid Earth" section of the 2015 revised curriculum, with the majority being at the 4^th-grade level. The 11^th-grade optional curriculum terms comprised the second largest portion, and 13.7% of all science terms were from outside the curriculum. Notably, variations in the scientific terminology's complexity was based on geological attractions. Specifically, the terminology level on the homepage tended to be generally higher than that on information boards. Through these findings, specific factors impeding visitor comprehension of geological attractions in the Yeoncheon area, based on the interpretation medium, were identified. We suggest further research to effect improvements in self-guided interpretation media, fostering geological resource education for general visitors and anticipating advancements in geology education.

• The Korean Journal of Pesticide Science
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• v.17 no.4
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• pp.448-453
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• 2013

We investigated the occurrence of major pests, 4 species of moths (Grapholita dimorpha Busck, Carposina sasakii Matsumura, Archips breviplicanus Walsingham, Adoxophyes orana Fischer von Roslerstamm), apple aphid (Aphis spiraecola Patch), two spotted spider mite (Tetranychus urticae Koch) and parasitoids in pear orchard with hairy vetch and cutting weeds in Yesan, Chungnam province during the flowering season and summer depression season of hairy vetch, in 2012 and 2013. The occurrence of 4 species of moths in hairy vetch plot and cutting weeds (major is finger grass, Digitaria sanguinalis, 80%) were little different but in case of apple aphid, the density in hairy vetch plot was just 95 aphids per stem at 20th June but low after then. The density of two spotted spider mite on pear leaf in hairy vetch plot was lower than in cutting weeds plot significantly. The number of parasitoids collected in hairy vetch plot during flowering season (May and June) were 398 and 798 in 2012 and 2013, respectively. The number of parasitoids collected in hairy vetch plot during summer depression season (July and August) were 114 and 172, respectively. But in cutting weeds plot, 9 and 22 in May and June, 8 and 5 in July and August. We didn't know either hairy vetch in pear orchard affected the occurrence of 4 species of moths, apple aphid and two spotted spider mite or not but was acted to be favorable for wasps, the natural enemies on the contrary. The improvement of chemical control systems through the selection of low chemicals to natural enemies with cover and green manure plants would turn effective pest management into a possibility.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.51 no.spc1
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• pp.107-112
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• 2006

Free Radical Scavening and inflammatory of the methanol extracts, which were prepared from 6 difffrent bran of rice, were evaluated to investigate bioactive substances. Among them, the extract of C3GHibyeo and Heugjinjubyeo showed strong DPPH scavening activities (73.25% and 50.38% at 0.4 mg/ml, respectively). The extract of C3GHibyeo and Heugjinjubyeo showed strong thrombin inhibition activities (258.76% and 243.52% inhibition at 5 mg/ml, respectively). The result of antibacterial activity by Zone assay showed that C3GHi rice extract $(250{\mu}g\;and\;500{\mu}g)$ inhibited attachment of Helicobactor pylori on the ATCC48504 and COO1 cell line. But no effect on the SEO cell line. Cytotoxicity of blackish purple rice extract on the H. pylori doesn't showed. These result support a functional superiority of rice-base livelihood, and suggest that the development of healthy food using functional ingredients of rice is possible.

• Journal of Dairy Science and Biotechnology
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• v.38 no.2
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• pp.112-120
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• 2020

This study was conducted to verify the physiological activity of heat-killed Enterococcus faecalis EF-2001 probiotics in fermented milk. The anti-inflammatory effects of fermented milk supplemented with different concentrations (0, 100, and 500 ㎍/mL) of E. faecalis EF-2001 were determined using MTT assay and nitric oxide inhibition assay. The MTT assay was performed using RAW 264.7 cells. Results revealed that the rates of cytotoxicity and cell survival decreased significantly with increase in the concentration of heat-killed probiotics (p<0.05). Moreover, fermented milk supplemented with 100 ㎍/mL EF-2001 (EFM1) and the fermented milk supplemented with 500 ㎍/mL EF-2001 (EFM2) exhibited higher nitric oxide inhibition than normal fermented milk (NFM). Additionally, EFM2 significantly reduced the ratio of prostaglandin E₂ compared to NFM (p<0.05). In conclusion, the treatment sample showed higher anti-inflammatory activity than NFM. The findings of this study could be used as a basic guideline for manufacturing of NFM supplemented with heat-killed probiotics.

• Journal of the Korean Society of Food Science and Nutrition
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• v.45 no.3
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• pp.445-451
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• 2016

This study demonstrated the immunological effects of methanol extracts from Doenjang added with wild plants (Pteridium aquilinum and Aster scaber) on bone-marrow derived macrophages and mouse splenocytes. Doenjang (DJ) and wild plant added Doenjang (WPDJ) extracts were treated to bone-marrow derived macrophages (BMDM) and splenocytes, and cell proliferation and cytokine production were measured. Cell proliferation of BMDM and splenocytes was more highly elevated in the WPDJ-treated group compared to the DJ-treated group. Cytokine [tumor necrosis factor (TNF)-${\alpha}$, interleukin (IL)-6, IL-$1{\beta}$, IL-10, and IL-12] production in BMDM also significantly increased in the WPDJ-treated group. Similarly, in the case of cytokine production in splenocytes, WPDJ treatment highly increased production of Th 1 type cytokines [interferon (IFN)-${\gamma}$ and IL-2] but did not affect production of Th 2 type cytokines (IL-4). These results suggest that wild plants could improve the immunomodulatory activity of Doenjang and may be effective for the development Doenjang.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.48 no.2
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• pp.113-121
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• 2022

In this study, fermented Lycium chinense (L. chinense) extract was used to analyze the efficacy of nitric oxide (NO) and anti-aging inhibition to verify its usefulness as a functional cosmetic material. L. chinense was extracted with hydrothermal and 70% ethanol as a solvent, fermented, concentrated, and freeze-dried to prepare a sample, followed by MTT assay, NO inhibition assay, western blot assay, and UPLC analysis.As a result of the analysis of NO inhibitory efficacy, fermented L. chinense water extract (FLW) and fermented L. chinense 70% ethanol extract (FLE) showed excellent NO inhibitory efficacy of 47.96% and 56.71%, respectively. As a result of measuring the expression patterns of the wrinkle-related proteins MMP-1, and TRPV-1 through Western blot, both FLW and FLE confirmed the inhibitory efficacy of MMP-1 and TRPV-1. Based on the results of the experiment, the fermented L. chinense extract is expected to have a high application value as a functional cosmetic material related anti-inflammatory, and anti-aging.