• Title/Summary/Keyword: 인터루킨-1 수용체 부속 단백질

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Effects of Environmental Factors Such as Temperature and Salinity on Expression of Interleukin-1 Receptor Accessory Protein in the Red Seabream (Pagrus major) (온도 및 염분 등의 환경요인이 참돔(Pagrus major)의 Interleukin-1 Receptor Accessory Protein 발현에 미치는 영향)

  • Kang, Han Seung;Min, Byung Hwa
    • Journal of Marine Life Science
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    • v.2 no.2
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    • pp.70-74
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    • 2017
  • Interleukin-1 (IL-1) is one of the proinflammatory cytokines, after IL-1 binds to IL-1RI, IL-1RacP (interleukin-1 receptor accessory protein) joins with IL-1/IL-1RI to form a complex, and leading to cell activation. IL-1RAcP is involved in immune response, stress and apoptosis. The purpose of this study was to investigate the gene expression of IL-1RAcP in red seabream (Pagrus major) exposure to low water temperature (8℃, 33 psu) and low salinity (20℃, 10 psu). Results showed that, the expression of IL-1RAcP was significantly increased in the experiment groups, such as low water temperature (8℃, 33 psu), and low salinity (20℃, 10 psu). These results suggest that IL-1RAcP was played roles in biomarker gene on the environmental stress such as low water temperature and low salinity.