• Proceedings of the Costume Culture Conference
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• 2004.04a
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• pp.87-88
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• 2004

본 연구는 피부의 노화방지 및 미백 효과에 탁월한 비타민 E를 섬유에 부착시켜 인체에 미치는 생리적 반응을 보기 위하여 온열감, 습윤감, 쾌적감의 주관적 감각평가와 심박수, 피부온, 의복내 온도 및 습도를 측정하였다. 연구방법 및 결과는 다음과 같다. 실험은 온도 30±1℃, 상대습도 50±15%, 기류 0.2m/s 이하로 설정된 인공기수실에서 실시하였다. 피험자는 평균연령 21세의 건강한 성인여자 5명으로, 체중, 신장 및 체표면적의 평균치는 52.2㎏, 161.2cm 및 155㎡이다. (중략)

• Proceedings of the Korean Society for Emotion and Sensibility Conference
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• 1997.11a
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• pp.113-117
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• 1997

본 논문은 여름철 체감실험에 대한 결과이다. 유니폼을 착용한 각 피험자(중학생, 대학생, 고령자)는 90분동안 환경시험실에 체재하면서 의자에 앉아 전신온냉감 및 쾌불쾌감을 신고하였다. 체감실험동안 피부온도는 인체의 3곳에서 측정하였고 피험자는 10분 간격마다 전신온냉감 및 쾌불쾌감을 신고하였다. 환경물리량및 인체 피부온도는 매 20초 간격으로 측정하였다. 여름철 체감실험 결과 아래의 결론을 얻었다. 1)평균피부온도가 증가함에 따라 TSV는 선형적으로 능가하며 열적으로 중립감을 느낄 때으리 평균피부온도는 고령자의 경우 남자 33.8$^{\circ}C$, 여자 34.3$^{\circ}C$이고, 대학생 남자의 경우 34.1$^{\circ}C$ ,여자 33.8$^{\circ}C$, 중학생의 경우는 34.4$^{\circ}C$이다. 2)발한량과 평균피부온도의 관계는 각 계층 모두 평균피부온도 34$^{\circ}C$를 전후로 급격히 상승함을 알 수 있다. 3)전신온냉감이 중립일 경우 고령자 남자의 SET＊=25.6$^{\circ}C$, 고령자 여자 28.4$^{\circ}C$, 대학생 남자 26$^{\circ}C$, 대학생여자 26.9$^{\circ}C$, 중학생 27.1$^{\circ}C$이었다.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.47 no.4
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• pp.341-352
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• 2021

Acerola is an excellent ingredient because of its high natural vitamin C content, but it is difficult to stabilize and has hardly been studied as a cosmetic material. Therefore, this study developed a mixed liposome preparation for stabilizing acerola extract. As a safety test, the skin irritation test was evaluated by BCOP assay and HET-CAM assay. We evaluated the inhibition of tyrosinase activity, the whitening effect of melanin production, and the wrinkle effect of prochloragentype-I C-peptide production, and confirmed the possibility of functional cosmetics. In addition, a cream of liposomes containing acerola extract mixture was developed to evaluate the clinical studies of skin wrinkles and whitening. BCOP assay, HET-CAM assay and human skin primary irritation test results of liposomes containing acerola extract mixture showed no irritation and were safe from skin and eye. The result of tyrosinase activity by 75.8% at 1,000 ㎍/mL. As a result of the melanogenesis inhibition test, liposome with acerola extract showed the melanin content by 46.2% at 1,000 ㎍/mL that does not effect the viability of the B16F10 cell line. The result of collagen production test using ELISA kit, liposomes containing acerola extract mixture showed collagen synthesis ability by 152.1% at 1,000 ㎍/mL that does not affect the viability of the HS68 cell line. But it did not showed any inhibition of collagenase (MMP-1) activity at all concentrations in the MMP-1 activity inhibition test in the HS68 cell line. We performed clinical studies for the whitening and skin-wrinkle activity of cream containing acerola extract mixes liposome, was showed that the melanin contents and wrinkle was statistically significant reduction. These results suggest that liposomes containing acerola extract mixture have safe natural material, and skin wrinkle, whitening effects allowing their application in cosmetics as a natural product.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.49 no.4
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• pp.331-339
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• 2023

In this study, in vitro and clinical studies were conducted to assess the anti-inflammatory effects and skin improvement effects, including moisturizing, sebum secretion-regulating, skin barrier function enhancing, and soothing of Helianthus annuus (Sunflower) seed oil. In in vitro study using cultured human epidermal keratinocytes induced with inflammation by lipopolysaccharide, significant decreases in inflammatory cytokines interleukin-6, interleukin-8, and tumor necrosis factor alpha was revealed, indicating the anti-inflammatory effects of H. annuus (Sunflower) seed oil. Additionally, the results of clinical study on subjects with sensitive skin demonstrated improved skin hydration, regulation of sebum secretion, enhanced skin barrier function, as well as amelioration of skin redness and acne, indicating positive effects on overall skin conditions after application of H. annuus (Sunflower) seed oil containing test product for 4 weeks. Results of this study demonstrated the potential of H. annuus (Sunflower) seed oil as an ingredient for cosmetic, targeting consumers with sensitive skin.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.32 no.2
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• pp.109-116
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• 2019

Survivability of soldiers has been greatly threatened by the development of thermal observation device(TOD). Therefore, infrared, especially thermal, stealth technology is applied to combat suit to avoid detection from TOD. In this study, prior to the thermal camouflage performance evaluation of combat suit, thermal signature characteristic from clothed the human body was analyzed considering the realistic condition for human surface temperature compared to that from unclothed human body. To get the realistic surface temperature distribution of human, thermoregulation and multi-layer skin structure model is applied to the human model. Based on temperature distribution, surface diffuse radiance in thermal range is calculated and by assuming the background conditions, contrast radiance intensity(CRI) characteristic of human body is analyzed. By wearing clothing, the CRI between background and human body became reduced in low emissive background but in high emissive background, the contrast is much more prominent. Therefore, this issue should be considered in design process of thermal camouflage combat suit.

• The Journal of the Korea institute of electronic communication sciences
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• v.9 no.12
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• pp.1427-1434
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• 2014

Among the medical devices, medical treatments inflicting physical energy from the outside of the body to the inside or using the energy from the devices which take advantages of chemical changes of the human body require a high degree of reliability and safety. In particular, the medical treatment on the most exposed skin to the external surface in all parts of the human body will be very important. In this perspective, when you undergo skin treatment, you need to reduce all risks and to maximize the effect of treatment equipment. Therefore, the development of equipment which guarantees high therapeutic efficacy and safety is essential.

• Journal of Society of Preventive Korean Medicine
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• v.2 no.1
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• pp.13-30
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• 1998

Geraniol (1), olivetol (2), cannabinoids (3 and 4) and 5-fluorou.a.il (5). were tested for their growth inhibitory effects against SK-MEL-3 cell lines using two different 3-(4,5-dimethylthiazol- 2yl)-2,5-diphenyl-2H-tetrazolium bromide (MTT) assay and sulforhodamine B protein (SRB) assay. These compounds showed inhibitory activity in vitro in the micromolar range against SK-MEL-3 cell lines. In general, the antitumor activity of these compounds (1, 2, 3, 4 and 5) was in a dose-dependent over the micromolar concentration range $1\;to\;100{\mu}M$. The comparison of $IC_{50}$ values of these compounds in tumor cell lines shows that their susceptibility to these compounds decrease in the following order : OLVTL > CBG > CBD > 5-FU > CRNL in MTT assay, CBG > OLVTL > CBD > GRNL > 5-FU in SRB assay. Cannabinoids (3 and 4) and 5-fluorouracil (5) were tested for their cytotoxic effects on NIH 373 fibroblasts using two different MTT assay and SRB assay. These compounds exhibited potent cytotoxic activities in vitro in the micromolar range against NIH 373 fibroblasts. In general, the cytotoxic activities of these compounds (3, 4 and 5) were in a dose-dependent over the micromolar concentration range $1\;to\;100{\mu}M$. The comparison of $CD_{50}$ values of these compounds on NIH 373 fibroblasts shows that their susceptibility to these compounds decrease on the following order ; CBD > 5-FU > CBG in MTT assay and SRB assay. Cannabigerol (3) was shown the least cytotoxic activity on NIH 373 fibroblasts. Cannabigerol (3) exhibited the most growth-inhibitory activity against SK-MEL-3 cell lines.

• Proceedings of the Korean Society for Emotion and Sensibility Conference
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• 2001.05a
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• pp.104-108
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• 2001

복사에 의한 냉난방은, 장시간 재실하는 방이나 소음, 기류에 민감한 장소에 적합하고 에너지 절약면에서도 유효한 냉난방 방식이라고 알려져 있다. 일반적으로 널리 알려져 있는 바닥난방은 실온의 수직분포가 균일함으로서 인체에 쾌적한 난방방식으로 알려져 있다. 이것에 비해, 바닥의외의 벽, 천장을 활용한 냉난방설비의 쾌적성에 대해서는 아직 충분히 검토되고 잇지 않다. 따라서 본 연구는 물순환식 복사 냉난방장치를 이용하여 겨울철의 천장복사난방이 인체에 미치는 생리적, 심리적영향을 밝히고 복사난방의 유용성에 대해서 검토하는 것을 목적으로 한다. 실험은 일본 나라여자대학 인공기후실을 이용하였고, 실험조건은 실온 18$^{\circ}C$, 21$^{\circ}C$, 24$^{\circ}C$ 천장온도 $25^{\circ}C$, 3$0^{\circ}C$, 35$^{\circ}C$의 조건을 조합하여 7조건으로 설정하였다. 또, 상대 습도 40%, 기류속도 0.1m/s 이하로 일정하게 유지시켰다. 생리적반응으로는 피부온14점과 직장온을 30초 간격으로 측정하였고, 혈압, 심박수, 체중, 체지방율을 측정하고 심리적반응으로는 온열감, 쾌적감등의 항목을 10분간격으로 측정하였다.

• Progress in Medical Physics
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• v.17 no.2
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• pp.83-88
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• 2006

Purpose: We Investigated to achieve high resolution magnetic resonance (MR) Imaging and spectra of human skin in vitro with using a 14.1 T MRI/MRS system, and to evaluate the hydration effect of a moisturizer by measuring the skin's water concentration. Materials and Methods: We used the Brukrer 14.1 T MRI/MRS system with a vertical standard bore that was equipped with a DMX spectrometer gradient system (200 G/cm at a maximum 40 A), RF resonators (2, 5 and 10 mm) and Para Vision software. Spin echo and fast spin echo pulse sequences were employed for obtaining the high resolution MR images. The 3D-localized point resolved spectroscopy (PRESS) method was used to acquire the MR spectra. Results: The high resolution MR images and spectra of human skin in vitro were successfully obtained on a 14.IT system. The water concentration of human skin after applying a moisturizer was higher than that before applying a moisturizer. Conclusions: The present study demonstrated that the high-resolution MR images and spectra of human skin from a high field MRS instrument could be applicable to evaluating the hydration state of the stratum corneum.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.7
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• pp.350-356
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• 2017

With increasing attention to real-time body detection, active research is being conducted on human body detection based on skin color. Despite this, most existing skin detection methods utilize static skin color models and have detection rates in images, in which colors are distorted. This study proposed a method of detecting the skin region using a fuzzy classification of the gradient map, saturation, and Cb and Cr in the YCbCr space. The proposed method, first, creates a gradient map, followed by a saturation map, CbCR map, fuzzy classification, and skin region binarization in that order. The focus of this method is to rigorously detect human skin regardless of the lighting, race, age, and individual differences, using features other than color. On the other hand,the borders between these features and non-skin regions are unclear. To solve this problem, the membership functions were defined by analyzing the relationship between the gradient, saturation, and color features and generate 108 fuzzy rules. The detection accuracy of the proposed method was 86.35%, which is 2~5% better than the conventional method.