• Title/Summary/Keyword: 인체장기분리

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Segmentation and Visualization of Human Anatomy using Medical Imagery (의료영상을 이용한 인체장기의 분할 및 시각화)

  • Lee, Joon-Ku;Kim, Yang-Mo;Kim, Do-Yeon
    • The Journal of the Korea institute of electronic communication sciences
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    • v.8 no.1
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    • pp.191-197
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    • 2013
  • Conventional CT and MRI scans produce cross-section slices of body that are viewed sequentially by radiologists who must imagine or extrapolate from these views what the 3 dimensional anatomy should be. By using sophisticated algorithm and high performance computing, these cross-sections may be rendered as direct 3D representations of human anatomy. The 2D medical image analysis forced to use time-consuming, subjective, error-prone manual techniques, such as slice tracing and region painting, for extracting regions of interest. To overcome the drawbacks of 2D medical image analysis, combining with medical image processing, 3D visualization is essential for extracting anatomical structures and making measurements. We used the gray-level thresholding, region growing, contour following, deformable model to segment human organ and used the feature vectors from texture analysis to detect harmful cancer. We used the perspective projection and marching cube algorithm to render the surface from volumetric MR and CT image data. The 3D visualization of human anatomy and segmented human organ provides valuable benefits for radiation treatment planning, surgical planning, surgery simulation, image guided surgery and interventional imaging applications.

An Algorithm of Automatic Segmentation by Region Growing (구역 확장을 응용한 의학 영상 자동 분리 알고리즘)

  • Seong, Won;Park, Jong-Won
    • Proceedings of the Korea Information Processing Society Conference
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    • 2002.04a
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    • pp.763-766
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    • 2002
  • 오늘날 CT나 MR 등을 통한 의학 영상 기술과 컴퓨터 성능의 향상으로 인체 내부 장기의 영상을 비교적 용이하게 얻을 수 있으며 얻어진 영상 정보는 컴퓨터로 수치화되므로 데이터의 조작 및 가공 또한 용이하다. 그러나, 이 데이터는 2D 슬라이스(slice)들의 연속으로 표현되므로 이것을 보다 가시화, 조작, 분석이 용이한 상태로 바꾸기 위해서는 3 차원 구조로의 재구성이 필요하게 된다. 이것을 위하여 무엇보다도 먼저 CT 나 MR 을 통하여 얻어진 영상을 분석하여 특정장기(organ)의 영상 부분을 다른 조직의 영상부분으로부터 분리(segmentation)할 필요가 있다. 이러한 Segmentation방법에는 여러가지가 있는데, 수작업의 결합 등으로 인해서 비효율적일 수 밖에 없는 문제점을 가지고 있다. 이에 본 논문은 보다 효율적인 segmentation 의 처리를 위하여 구역확장(region-growing) 기법을 응용한 새로운 segmentation 방법을 개발하였다. 그리하여, 본 논문이 제안한 알고리즘을 슬라이스 간격이 큰 2 차원 복부 CT 영상에 적용시켜 간(liver)의 추출을 시도하였고 3차원 표현 결과를 확인할 수 있었다.

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A Method of Automatic Segmentation in 3-Dimensional CT image (3차원 CT 영상을 위한 자동 :Segmentation 기법)

  • Seong, Won;Kim, Jae-Pyeong;Park, Jong-Won
    • Proceedings of the Korean Information Science Society Conference
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    • 2002.04b
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    • pp.634-637
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    • 2002
  • 오늘날 CT나 MR등을 통한 의학 영상 기술과 컴퓨터 성능의 향상으로 인체 내부 장기의 영상을 비교적 용이하게 얻을 수 있으며 얻어진 영상 정보는 컴퓨터로 수치와 되므로 데이터의 조작 및 가공이 용이하다. 그러나, 이 데이터는 2D 슬라이스들의 연속으로 표현되므로 이것을 보다 편리하게 가시화. 조작, 분석이 용이한 상태로 바꾸기 위해서는 3차원 구조로의 재구성이 필요하게 된다. 이것을 위하여 무엇보다도 먼저 CT나 MR을 통하여 얻어진 영상을 분석하여 특정 장기의 영상 부분를 다른 조직의 영상부분으로부터 분리(segmentation)할 필요가 있다. 이러한 Segmentation방법에는 여러가지가 있는데, 수작업의 결합 등으로 인해서 비효율적인 문제점을 가지고 있다. 이에 본 논문은 보다 효율적인 segmentation의 처리를 위하여 region-based 기법을 응용하여 새로운 segmentation 방법을 개발하였다. 그리하여, 본 논문이 제안한 알고리즘을 슬라이스 간격이 큰 2차원 복부 CT 영상에 적용시켜 간(liver)의 추출을 시도하였고 향상된 성능을 확인할 수 있었다.

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Infection status of anisakid larvae in anchovies purchased from local fishery market near southern and eastern sea in Korea (해안지역에서 시판되는 멸치의 anisakid 유충 감염상)

  • 송수복;이상룡
    • Parasites, Hosts and Diseases
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    • v.33 no.2
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    • pp.95-100
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    • 1995
  • A survey was carried out on the larval anilsakids in anchovies (Engrnuyis jnponica) which were caught from April to .lune in 1993 at the southern and eastern sea in Korea. Anisakids in anchovies were morphological classified into Anisakis type I and II and Contracaecum type B and C, after fixation in 70% alcohol and clearing in lactophenol. A examined. The infection rates showed no relation with length of the anchovies. The numbers of anisakids by organs of anchovies were 96 (56.1%) from the muscle, 65 (38.0%) from the omentum, 7 (4.1%) from the intestine, 2 (1.7%) from the stomach and 1 (0.6%) from the testis. Infection rates of anchovies with anisakids by localities were 5.1% at Taebyon, 8.0% at Sokcho and 9.2% at Chungmu. The larval uisikids in anchovies may infect humans who often eat raw anchovies.

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Auto-Segmentation Algorithm For Liver-Vessel From Abdominal MDCT Image (복부 MDCT 영상으로부터 간혈관 자동 추출 알고리즘)

  • Park, Seong-Me;Lee, You-Jin;Park, Jong-Won
    • Journal of Korea Multimedia Society
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    • v.13 no.3
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    • pp.430-437
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    • 2010
  • It is essential for living donor liver transplantation that surgeon must understand the hepatic vessel structure to improve the success rate of operation. In this paper, we extract the liver boundary without other surrounding structures such as heart, stomach, and spleen using the contrast enhanced MDCT liver image sequence. After that, we extract the major hepatic veins (left, middle, right hepatic vein) with morphological filter after review the basic structure of hepatic vessel which reside in segmented liver image region. The purpose of this study is provide the overall status of transplantation operation with size estimation of resection part which is dissected along with the middle hepatic vein. The method of liver extraction is as follows: firstly, we get rid of background and muscle layer with gray level distribution ratio from sampling process. secondly, the coincident images match with unit mesh image are unified with resulted image using the corse coordinate of liver and body. thirdly, we extract the final liver image after expanding and region filling. Using the segmented liver images, we extract the hepatic vessels with morphological filter and reversed the major hepatic vessels only with a results of ascending order of vessel size. The 3D reconstructed views of hepatic vessel are generated after applying the interpolation to provide the smooth view. These 3D view are used to estimate the dissection line after identify the middle hepatic vein. Finally, the volume of resection region is calculated and we can identify the possibility of successful transplantation operation.

The Effect of Emotional Experiences on Biological Aging (정서경험과 생체노화)

  • Paik, Seo Chae;Kim, Jong Sung
    • Korean journal of health promotion
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    • v.18 no.4
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    • pp.147-158
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    • 2018
  • Background: This study was designed to investigate the effects of usual negative emotional experiences on biological aging progression of human. Methods: A total of 237 subjects who visited the Health Promotion Center at Chungnam National University Hospital from May 2013 through September 2013 was enrolled. Each subject had been drawn up a structured questionnaire about usual experiences of depression, anxiety, anger, and anger expression. The degree of biological aging progression of each subject was computed by a specific formula which consisted of chronological age and biological age reflecting obesity and aging of main organs. Results: Trait anger and low education level showed the significant correlations with biological aging (r=0.160, P=0.014, and r=-0.189, P=0.024, respectively). Trait anger and low education level solely displayed the significant $R^2s$ for biological aging in consequence of multivariate analyses; $R^2=0.044$, P=0.020, and $R^2=0.022$, P=0.038, respectively. Conclusions: This study suggests that the significant relationship between usual anger experience (i.e., trait anger) and biological aging would be present. In addition, lower education level may be related with biological aging.

The research for the yachting development of Korean Marina operation plans (요트 발전을 위한 한국형 마리나 운영방안에 관한 연구)

  • Jeong Jong-Seok;Hugh Ihl
    • Journal of Navigation and Port Research
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    • v.28 no.10 s.96
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    • pp.899-908
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    • 2004
  • The rise of income and introduction of 5 day a week working system give korean people opportunities to enjoy their leisure time. And many korean people have much interest in oceanic sports such as yachting and also oceanic leisure equipments. With the popularization and development of the equipments, the scope of oceanic activities has been expanding in Korea just as in the advanced oceanic countries. However, The current conditions for the sports in Korea are not advanced and even worse than underdeveloped countries. In order to develop the underdeveloped resources of Korean marina, we need to customize the marina models of advanced nations to serve the specific needs and circumstances of Korea As such we have carried out a comparative analysis of how Austrailia, Newzealand, Singapore, japan and Malaysia operate their marina, reaching the following conclusions. Firstly, in marina operations, in order to protect personal property rights and to preserve the environment, we must operate membership and non-membership, profit and non-profit schemes separately, yet without regulating the dress code entering or leaving the club house. Secondly, in order to accumulate greater value added, new sporting events should be hosted each year. There is also the need for an active use of volunteers, the generation of greater interest in yacht tourism, and the simplification of CIQ procedures for foreign yachts as well as the provision of language services. Thirdly, a permanent yacht school should be established, and classes should be taught by qualified instructors. Beginners, intermediary, and advanced learner classes should be managed separately with special emphasis on the dinghy yacht program for children. Fourthly, arrival and departure at the moorings must be regulated autonomically, and there must be systematic measures for the marina to be able, in part, to compensate for loss and damages to equipment, security and surveillance after usage fees have been paid for. Fifthly, marine safety personnel must be formed in accordance with Korea's current circumstances from civilian organizations in order to be used actively in benchmarking, rescue operations, and oceanic searches at times of disaster at sea.

Antitumor Activity of CBT-AK5 Purified from Lactobacillus casei against Sarcoma-180 Infected ICR Mice (유산균의 배양물로부터 분리된 물질에 대한 암 유발 ICR Mice의 항암 효과)

  • Yeo, Moon-Hwan;Kim, Dong-Myung;Kim, Yong-Hwan;Kim, Jung-Hwa;Baek, Hong;Chung, Myung-June
    • Journal of Dairy Science and Biotechnology
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    • v.26 no.2
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    • pp.23-30
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    • 2008
  • This study implicated that the CBT-AK5 purified from Lactobacillus casei (LAFTI L26) which showed antitumor activity in ICR mice. Hence, ICR mice were inoculated intraperitoneally Sarcoma-180 as well as CBT-AK5. Then we observed the life span and tumor increment of those ICR mice. Here our studies showed effect on two different way of treatment as intraperitoneally and orally treated in Sarcoma-180 infected ICR mice. We found that intraperitoneally treatment of Sarcoma-180 and CBT-AK5 is more effective than orally fed. The life span of the ICR mice were highly reduced after the inoculation of Sarcoma-180. Those effects like increment of body weight, the growth of ascites and solid were inhibited significantly after the treatment of CBT-AK5 in Sarcoma-180 infected ICR mice. Finally these studies suggested that CBT-AK5 isolated form Lactobacillus casei showed excellent antitumor activity against Sarcoma-180 infected ICR mice.

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Applying QFD in the Development of Sensible Brassiere for Middle Aged Women (QFD(품질 기능 전개도)를 이용한 중년 여성의 감성 Brassiere 개발)

  • Kim Jeong-hwa;Hong Kyung-hi;Scheurell Diane M.
    • Journal of the Korean Society of Clothing and Textiles
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    • v.28 no.12 s.138
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    • pp.1596-1604
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    • 2004
  • Quality Function Deployment(QFD) is a product development tool which ensures that the voice of the customer needs is heard and translated into products. To develop a sensible brassiere for middle-aged women QFD was adopted. In this study the applicability and usefulness of QFD was examined through the engineering design process for a sensible brassiere for middle-aged women. The customer needs for the wear comfort of brassiere was made by one-on-one survey of 100 women who aged 30-40. The customer competitive assessment was generated by wearing tests of 10 commercial brassieres. The subjective assessment was conducted in the enviornmental chamber that was controlled at $28{\pm}1^{\circ}C,\;65{\pm}3\%RH.$ As a results, we developed twenty-one customer needs and corresponding HOWs for the wear comfort of brassiere. The Customer Competitive Assessment was generated by wearing tests of commercial brassiere. The subjective measurement scale and dimension for the evaluation of sensible brassiere were extracted from factor analysis. Four factors were fitting, aesthetic property, pressure sensation, displacement of brassiere due to movement. The most critical design parameter was wire-related property and second one was stretchability of main material of brassiere. Also, wearing comfort of brassiere was affected by the interaction of initial stretchability of wing and support of strap. Engineering design process, QFD was applicable to the development of technical and aesthetic brassieres.

Protective Effect of Nitroglycerin on the Ischemia-Reperfusion Model of the Isolated Rat Lung (흰쥐의 분리 폐장 관류 모델에서 Nitroglycerin의 폐장 보존 효과)

  • Jheon, Sang-Hoon;Lee, Sub;Lee, Jong-Hoon;Son, Bok-Kyoung;Cho, Gong-Rae;Chung, Jin-Yong;Cho, Soung-Kyung;Kim, Bong-Il;Lee, Young-Man;Choh, Joong-Haeng
    • Journal of Chest Surgery
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    • v.36 no.12
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    • pp.894-903
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    • 2003
  • Protection against ischemia-reperfusion injury is crucial for successful transplantation of the lung. It has been known that nitric oxide has many favorable effects on the donor lungs but at the same time, has some potential side effects of cytotoxicity. In this regards, we investigated whether the administration of nitroglycerin could decrease ischemia-reperfusion injury in isolated rat lung reperfusion model for the confirmation of the effect of nitroglycerin, a donor of nitric oxide, on lung transplantation. Material and Method: 35 Sprague-Dawley species male white rats were used for this experiment. For nitroglycerin group (n=18), nitroglycerin was administered intravenously followed by mixed in flushing solution for preservation. As a control group (n=17), we used the same amount of normal saline. To evaluate the effect of nitroglycerin on the lung, heart-lung block was obtained, weighed and stored in University of Wisconsin Solution at 1$0^{\circ}C$ for 24 hours. In each group of the isolated lungs, reperfusion was carried out with Krebs-Hensleit-diluted human blood for 60 minutes. As parameters of the state of the isolated lung, peak inspiratory and pulmonary arterial pressures were continuously recorded. Oxygen and carbon dioxide tension of reperfusing blood were measured before and after 30, 60 minutes of reperfusion. After sixty minutes of reperfusion, protein content in bronchoalveolar lavage fluid was measured also for the evaluation of the degree of alveolar flooding. Lung myeloperoxidase activity was determined to verify the accumulation of neutrophils. Results: Although statistically significant differences were not noted in peak inspiratory and pulmonary arterial pressure between control and nitroglycerin group, latter group showed lowering tendency of pulmonary arterial pressure during the entire reperfusion period. Oxygen tension was higher (p<0.05) in nitroglycerin group compared with that of the control group, in contrast, there were no differences in carbon dioxide tension, protein content in bronchoalveolar lavage fluid and myeloperoxidase activity between the groups. In the examination of ultrastructural changes, nitroglycerin denoted the protective effect on the pulmonary architecture compared with that of control group. Conclusion: Collectively, on the bases of these experimental results, prior treatment of donor lung with nitroglycerin could result in better preservation of the lung. Consequently, these nitroglycerin preserved lungs are thought to be more suitable for successful transplantation of the lung.