• Journal of the Korean Society of Radiology
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• v.11 no.5
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• pp.353-359
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• 2017

The sonophoresis, a representative low-intensity ultrasonic therapy, is a technique for delivering the drugs into the epidermis, dermis and skin appendages by using physical vibration and heat effects of the ultrasonic waves. Sonophoresis could increases the delivering and absorption efficiency of the drugs usually consisting of hydrophilic molecules and macromolecules. In addition, it has the advantage of being effective in delivering drugs with relatively large molecular sizes such as insulin or lipid. In this study, we proposed a multi-structure ultrasonic transducer assembly with a large-size single piezoelectric element and a drug delivery function at the treatment site for efficient sonophoresis treatment. Futhermore, a transducer assembly structure capable of raising and maintaining the temperature of the treatment site was proposed and evaluated for effectiveness. The transducer assembly proposed in this study is expected to improve the efficiency of sonophoresis by providing a constant amount of drug, and assisting drug delivery through heating the treatment site.

• Parasites, Hosts and Diseases
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• v.28 no.3
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• pp.155-160
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• 1990

The tribocytic organ and tegument of Fibricola seeulensis were examined histochemically for the detection of carbohydrates, mucosubstances, amyloid, collagen and alkaline phosphatase. The surface, secretes, gland cells of the tribocytic organ, and the tegument of the worms were positive to periodic acid Schig (PAS) and PAS with diastase stain but negative to other stains. It was inferred that the tribocytic organ and tegument of F. seoulensis comprise neutral mucopolysaccharides, which may take a protective role against host enzymes. The surface and secretes of the tribocytic organ, and the tegument of the worms were also Positive to double bridge PAP for alkaline phosphatase. This fact suggests that they may play a role as both self protective and host tissue Iytic functions.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.15 no.1
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• pp.581-584
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• 2014

Skin is the soft outer covering of vertebrates. In mammals, the skin is the largest organ of the integumentary system made up of multiple layers of ectodermal tissue, and guards the underlying muscles, bones, ligaments and internal organs. There is a difference of the physiological function and anatomical structure of the skin, as body parts, sex, age, race and nutritional status. In this study, we measured the moisturizing ability of the skin of the 20s Chinese and Korea in Korean. We found that the skin hydrating of Chinese is significantly higher than Korean and TEWL of Chinese is lower than Korean. We measured the moisturizing ability of both 20s Chinese and Korean. As result, the moisturizing ability of 20s Chinese is better than Korean.

• The Korean Journal of Physiology
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• v.20 no.2
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• pp.209-217
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• 1986

The functional molecular weight of band 4.5 polypeptide was measured by applying the classical target theory to radiation inactivation data of the cytochalasin B binding. Band 4.5 polypeptides purified from human erythrocyte membranes were irradiated at -45 to $-50^{\circ}C$ with an increasing dose of 1.5 MeV electron beam, and after thawing, cytochalasin B binding activities were assayed. Each activity measured was reduced as a simple exponential function of radiation dose. $D_{37}$, dose appeared to be 6.7 mega rads, from which the target size (radiation sensitive mass) of band 4.5 polypeptide was calculated to be 95,500 daltons. This result with other informations available in literature suggests that band 4.5 polypeptide may exist as a dimer in human erythrocytes.

• The Magazine of the Society of Air-Conditioning and Refrigerating Engineers of Korea
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• v.33 no.4
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• pp.17-22
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• 2004

가정용 공기청정기의 집진, 탈취, 각종 부가기능 등의 개발 현황 및 성능시험 결과와 사회환경 변화에 따른 시장 동향을 소개한다. 건강과 환경에 대한 관심이 점점 높아져 가는 사회적 분위기 속에서 특히 인간에게 직접적으로 영향을 미치는 실내 공기질에 대한 문제는 사회적으로 중대한 이슈가 되고 있다. 사회구조가 변화하면서 실내에서 생활하는 시간이 점점 길어지고 이에 따라 실내 환경이 인간에게 미치는 영향 또한 커지고 있다. 특히 실내공간에서 부유 하는 분진, 세균류와 유기화합물(volatile organic compounds : VOCs), 포름알데히드(HCHO) 등이 인체에 미치는 영향에 대한 연구 결과가 대중에게 알려지면서 실내 공기질 개선에 대한 사회적 요구가 급증하고 있는 것이 사실이다. 따라서 최근 공기청정기의 수요가 호조를 보이고 있으며, 백색가전제품 중에서도 두자리수 성장을 계속하고 있는 상품 중 하나이다. 공기청정기는 건강을 지향하는 추세가 강한 요즘, 필수품으로서 정착했으며 well-being붐을 타고 더욱 확대되고 있다.(중략)

• Progress in Medical Physics
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• v.24 no.1
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• pp.48-53
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• 2013

Monte Carlo method has been known as the most accurate method for calculating absorbed dose in the human body, and an anthropomorphic phantom has been mainly used as a method of simulating internal organs for using such a calculation method. However, various efforts are made to extract data on several internal organs in the human body directly from CT DICOM files in recent Monte Carlo calculation using Geant4 code and to use by converting them into the geometry necessary for simulation. Such a function makes it possible to calculate the internal absorbed dose accurately while duplicating the actual human anatomical structure. Thus, this study calculated the absorbed dose in the human body by using Geant4 associating with DICOM files, and aimed to confirm the usefulness by compare the result with the measured dose using a Gafchromic EBT2 film. This study compared the dose calculated using simulation and the measured dose in beam central axis using the EBT2 film. The results showed that the range of difference was an average of 3.75% except for a build-up region, in which the dose rapidly changed from skin surface to the depth of maximum dose. In addition, this study made it easy to confirm the target absorbed dose by internal organ and organ through the output of the calculated value of dose by CT slice and the dose value of each voxel in each slice. Thus, the method that outputs dose value by slice and voxel through the use of CT DICOM, which is actual image data of human body, instead of the anthropomorphic phantom enables accurate dose calculations of various regions. Therefore, it is considered that it will be useful for dose calculation of radiotherapy planning system in the future. Moreover, it is applicable for currently-used several energy ranges in current use, so it is considered that it will be effectively used in order to check the radiation absorbed dose in the human body.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.18 no.7
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• pp.1610-1618
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• 2014

Wearable computer systems can use the wireless universal serial bus (WUSB) that refers to USB technology that is merged with WiMedia PHY/MAC technical specifications. In this paper, we focus on an integrated system of the wireless USB over the IEEE 802.15.6 wireless body area networks (WBAN) for wireless wearable computer systems supporting U-health services. And a communication structure that performs the hibernation for low power consumption is proposed for WUSB over IEEE 802.15.6 hierarchical protocol. In the proposed hibernation mechanisms, WUSB communications are permitted at each m-periodic inactive periods of WBAN superframes by using the WBAN information of Wakeup Period and Wakeup Phase message fields. In our performance evaluations, performances according to amount of WUSB traffic and Wakeup Periods are analyzed respectively to evaluate the effectiveness of proposed hibernation structure in WUSB over IEEE 802.15.6.

• Therapeutic Science for Rehabilitation
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• v.3 no.2
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• pp.5-48
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• 2014

Introduction : One of the important domains in OT is performance skills which include sensory perceptual skills, motor and praxis skills, emotional regulation skills, cognitive skills, and communication/social skills. All of these skills are support ed by integrated neurological processes. Body : Stereology robust tool when employed to investigate morphological changes in neurons, cortex area, and specific parts of brain involved in special brain function. Stereology is an interdisciplinary field focused or analyzing biological tissue with the three-dimensional interpretation of planer sections by using estimating method and mathematically unbiased sampling. With the unbiased stereological method based on probability theory, researchers can estimate morphological and anatomical changes in biological reference areas accurately and efficiently. Changes in anatomical and cytoarchitectural parameters, such as volume, number, and length, affect specific brain function related to the brain area. Occupational therapists provide treatment to improve functions for participation of occupation in neurological disorder. The functional improvements in neurological disorder reflect neurobiological changes because functional difficulties, such as motor cognitive disorder, are due to neurological disturbances. Thus, combination of two kinds of evidence, neurological changes and functional improvement, provide fundamental evidence for OT intervention in neurological disorder. Even though most of stereological studies are in animal model and in postmortem human because of practical and ethical issues, stereology provides fundamental knowledge to support OT theory and practice. Conclusion : Therefore, stereology informs translation from neuroscience to OT based on structure-function relationship in performance skills and experience-dependent neural plasticity.

• Polymer(Korea)
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• v.37 no.5
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• pp.625-631
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• 2013

Mucoadhesive property is the major function as an adhesive for medical devices, and therefore, these days many researches have conducted to develop polymers having this property. Recently, biomimetic technology has been used for developing mucoadhesive polymers. Among many technologies, mussel-inspired approaches have received noticeable attention because of its thread's strong adhesive characteristics. In this study, we synthesized mucoadhesive biomimetic polymers employing catechol structures which are abundant in mussel adhesive proteins, and their structures and molecular weights were characterized by using nuclear magnetic resonance spectroscopy and gel permeation chromatography. To evaluate in vitro mucoadhesive strength, the sheet type of the small intestinal porcine submucosa was prepared. Compared to commercial fibrin glue adhesives, catechol-containing mucoadhesive polymers showed enhanced adhesive strength. The study of adhesive strength with considering diverse factors, such as temperature, pressure, and oxidant amount indicated that mussel-inspired mucoadhesive polymer could be a promising candidate for an adhesive in various biomedical applications.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.18 no.7
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• pp.1619-1627
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• 2014

Wearable computer systems can use the wireless universal serial bus (WUSB) that refers to USB technology that is merged with WiMedia PHY/MAC technical specifications. In this paper, we focus on an integrated system of the wireless USB over the IEEE 802.15.6 wireless body area networks (WBAN) for wireless wearable computer systems supporting U-health services. And a communication structure that performs the time-synchronization is proposed for WUSB over IEEE 802.15.6 hierarchical protocol. Proposed time-synchronization mechanisms adopt the WBAN Polling Access and combine it with a time-synchronization middleware using time stamps. In our performance evaluations, time-synchronization performances with only WBAN Polling Access scheme are analyzed first. After that, performances combined with the time-synchronization middleware are analyzed to evaluate the effectiveness of proposed time-synchronization structure in WUSB over IEEE 802.15.6.