• Journal of Korean Ophthalmic Optics Society
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• v.13 no.4
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• pp.95-101
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• 2008

Purpose: The aim of this research was to propose a program that can be used the Binocular Eye Visual Perception Training. Methods: This program can be used as a tool for binocular vision and vision training. The system that was made up of module was available in the stereosis and the vergence training. Results: In case of input module, this program could estimate the distance by using fixation disparity. Also, our margin of erroe is less then 5%. In case of output module, 28 trainers were examined by stereoscopic vision and visual depth perception. Conclusions: Therefore, the system can be used as a tools for the vision training.

• Journal of the Korean Society of Food Science and Nutrition
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• v.43 no.3
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• pp.360-366
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• 2014

Kimchi is a Korean traditional fermented food with various health functionalities. However, the protective effects of kimchi against Alzheimer's disease (AD) have not been studied yet. In this study, the protective activities of kimchi extract against oxidative stress and AD were investigated in an amyloid beta ($A{\beta}$)-induced AD model using ICR mice. Kimchi extract exerted strong scavenging activities against 1,1-diphenyl-2-picrylhydrazyl and hydroxyl radical. In addition, T-maze, object cognition, and water maze tests were carried out using the AD model. The $A{\beta}_{25-35}$-injected groups showed impairment of cognition and memory. However, the abilities of novel object recognition and new route awareness were improved by administration of kimchi extract (100 and 200 mg/kg/day) for 2 weeks. Furthermore, the results on water maze test indicated that kimchi extract exerted protective activity against cognitive impairment induced by $A{\beta}_{25-35}$. The present study suggested that kimchi protected against $A{\beta}$-induced impairment of memory and cognition as well as attenuated oxidative stress.

• Proceedings of the Korean Society for Cognitive Science Conference
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• 2005.05a
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• pp.261-266
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• 2005

본 논문은 고기능 자폐 아동들이 담화 주제어 연속성(topic continuity)을 어떻게 습득하는지에 대해 검토하였다. 연구의 목적을 위하여 세 고기능 자폐 아동(9;11-12:2)의 자연 발화를 관찰 분석하였다. 사전 연구에 의하면, 자폐아동들은 의사소통의 기본적인 규칙을 잘 이해하지 못할 뿐만 아니라 타인의 사고와 기대 등에 민감하지 못하여 담화 주제를 적절히 유지하거나 전환하는(topic shift) 일에 많은 어려움을 겪는다. 본 연구는 한국 자폐아동들이 주제어의 유지와 전환 등, 담화 화용적(discourse-pragmatic) 기능의 발달 양상을 규명하는 것을 주요 목표로 한다. 본 연구의 자료는 세 자폐 아동의 자연 발화 내용으로서 1주-2주에 한번씩 매번 방문 시 120분 동안 녹음하였다. 분석 결과 다음의 몇 가지 습득 양상을 발견하였다. 첫째, 세 자폐 아동들에게서 발견된 주제 유지 빈도는 정상 아동들에 비해 낮았다. 한편. 이 아이들은 가끔 화제를 자신의 담화 주제로 돌려 자신의 주제 중심으로 대화를 지속했다. 이 아동들은 대화 상대자의 주제에 대해서는 민감하지 않지만 자신의 주제를 유지하려는 경향을 보이기도 한다. 둘째, 개별 아동을 검토한 결과, 담화 주제의 지속성이 높은 발화를 하는 아동은 현재 담화 주제에 더 민감하고 반향어를 산출할 때에도 자기 자신의 말 반복과 담화 상대자의 말을 반복하는 빈도가 별로 차이가 나지 않았다. 반면, 담화 주제의 지속성이 낮은 발화를 하는 아동은 이전 담화 주제에 더 민감하고, 반향어는 담화 상대자의 말 보다는 자기 자신의 말을 반복하는 비율이 더 높았다. 본 연구의 결과는 자폐 아동들이 담화 주제를 지속하는 능력이 많이 부족하지만, 담화 주제의 연속성은 다른 발화 유형과 상호 작용을 하면서 발달될 수 있다는 가능성을 보여 주었다. 따라서 본 연구 결과는 앞으로 자폐 아동의 연구가 집단 간의 연구뿐만 아니라 개별 아동의 발화에 쓰인 유형 간의 상호 관계를 주목함으로써 자폐 아동의 개별적 언어 치료에 새로운 시각을 심어 줄 가능성을 시사한다.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.12 no.7
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• pp.3310-3316
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• 2011

Hematoxylin is the main component of Hematoxylon campechianum which has been utilized in the southern provinces of Korea as a folk remedy for diabetic complications. In the present study, to investigate the hypoglycemic mechanism of hematoxylin, the 2-deoxyglucose uptake and phospholipid metabolism were examined in sciatic nerves from three groups of rats : normal control, diabetic control, diabetic hematoxylin-treated group. Hematoxylin significantly reduced blood glucose levels in diabetic control rats. On a wet weight basis, the nerves from diabetic rats showed a 20% decrease in total phospholipid from that of controls and a relative decrease in phosphatidylinositide. Hematoxylin treatment increased the incorporation rate of 2-[3H] myo-inositol into total phosphoinositids in diabetic rat. The effectiveness were more potent in higher dose hematoxylin-treated rats than lower dose hematoxylin-treated rats. These results suggest that hematoxylin increases glucose transport and lipid metabolism by partially normalizing concerned with myo-inositol metabolism in diabetic rat. Therefore we propose that hematoxylin can be a promising candidate for diabetes medication.

• Cartoon and Animation Studies
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• s.45
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• pp.299-320
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• 2016

The interests of education methods using Serious games have been increasing recently. But resu,lt-oriented game design framework have not been reflected intrinsic motivation. To increase usage of educational serious game as resource, it is needed game design framework for providing the immersion and collaborative active learning that cognitive Psychologic theories recommend. By outlining the background of the serious game design framework and exemplifying its use, a constructive structure to examine purposed based games is introduced.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.7
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• pp.645-655
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• 2020

This is a descriptive study investigating the relationships between sexual function, depression, and sleep quality in male hemodialysis patients. The participants of this study consisted of 134 outpatients who were diagnosed with end stage chronic kidney disease and who had undergone hemodialysis. The data were collected from June 10, 2019, to October 30, 2019. The collected data were then analyzed using descriptive statistics, the mean from independent sample t-tests, one-way analysis of variance (ANOVA), the Scheffe test, and Pearson's correlation coefficient using SPSS version 21.0. The lower the overall satisfaction, the lower the sexual function and the higher the degree of depression (r=.-19, p=.028). The greater the depression, the lower the quality of sleep (r=.60, p<.001). This study shows it is necessary to develop a program including symptom management to reduce depression in male hemodialysis patients. When developing nursing interventions to improve sexual function and quality of sleep, it will be necessary to develop a program that includes people who help the subjects.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2013.10a
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• pp.207-210
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• 2013

Recently, rapid innovation of Smartphone is changing the paradigm of our daily life. Smartphone users, opinion experts more than 99 percent of the economically active population is using, it has reached the saturation past the early stages of formation. Smartphone is equipped with a general purpose OS possible the implementation of high performance environment similar level as a personal computer. Also, it is a mobile communication terminal scalable which can be removed or installed various applications. Such extensibility, it is possible to use different applications through the Apps store. In addition, it is also possible various services which are location based service. However, these services also benefit many but it also has a disadvantage of invasion of privacy and disclosure of personal information. In this research, we aim to analyze factors influencing on perceived value and risk in location based service of Smartphone. In addition, we aim to analyze the causal relationship with perceived value and risk in satisfaction and recommendation intention. This study suggests practical and theoretical implications based on the results.

• Korean Journal of Food Science and Technology
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• v.44 no.4
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• pp.447-451
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• 2012

In order to investigate the efficacies for cognitive function of edible plants, we measured the inhibitory effects of acetylcholinesterase(AChE) activity, radical scavenging activities, and the contents of GABA and glutamate in the plant extracts. Among the plant extracts, Schizandra chinensis contained the highest GABA 14.8 mg/g and the extracts of Cnidium officinale and Polygonum multiflorum also had a relatively high GABA. On the other hand, plant extracts except, Acorus gramineus, showed similar glutamate contents. S. chinensis, Hovenia dulcis, Thuja orientalis, and Eleutherococcus senticosus exhibited high inhibition against AChE activities at about 18-33% at 1 mg/mL. In addition, strong radical scavenging activities were also detected in those extracts which showed high AChE inhibition. Taken together, H. dulcis, T. orientalis, E. senticosus, and S. chinensis could be effective resources for enhancing cognitive function. Further, it was suggested that the AChE inhibitory activities of plant extracts might be related to antioxidative activity.

• Korean Journal of Optics and Photonics
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• v.33 no.4
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• pp.177-186
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• 2022

The performance of a surface plasmon resonance sensor is evaluated based on the sensitivity (nm/RIU) and sharpness from the full width at half maximum (FWHM) and the peak depth of a resonance peak. These factors are determined by the materials and conformational properties of the sensing structure. In this paper, we investigated an optimized insulator-metal-insulator (IMI) multilayer-based surface plasmon resonance sensor structure to simultaneously achieve high sensitivity, narrow FWHM, and deep peak depth while using gold for the metallic film layer which occurs peak broadening. By adopting the optimized structure, sensitivity of 8,390 nm/RIU, FWHM of 11.92 nm, and a resonance peak depth of 93.1% were achieved for 1.45-1.46 refractive index variation of the sensing layer. With the suggested structure conformation, high sensitivity and resolution of sensing performance can be achieved.

• Korean Journal of Cognitive Science
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• v.14 no.4
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• pp.43-51
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• 2003

The present paper is concerned with assessing both communicational skills and grammatical knowledge in three Korean-speaking children with a range in age from 9;11 to 12;2 and in MLU from 1.68 to 2.22. It was found that all three autistic children's speech was largely repetitive and echolalic, unable to consistently interact communicatively on the ongoing joint focus of attention. It was also observed that the more repetitive the child speech was, the more impaired morpho-syntactically it was. Based on these findings, it was speculated that the deficit in joint focus of attention might relate to grammatical development.