• Journal of Korean Medicine Rehabilitation
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• v.25 no.1
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• pp.1-15
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• 2015

Objectives The aim of this study was to investigate the effects of Cannabis Fructus on exercise capacity and cognitive function in chronic hypoperfusion induced vascular dementia rat model. Methods Vascular dementia rat models were induced by chronic cerebral hypoperfusion through bilateral common carotid arteries occlusion (BCCAO). All rats were randomly divided into 4 groups: normal group; control group; CF I group (feeding Cannabis Fructus 100 mg/kg); CF II group (feeding Cannabis Fructus 300 mg/kg). In order to study the effects of oral administration of Cannabis Fructus on vascular dementia rat models, corner turn test, hole board test, radial arm maze test, passive avoidance test were taken and Acetylcholine (ACh) activity, Acetylcholinesterase (AChE) activity, serum of Vascular endothelial growth factor (VEGF) protein level were measured. Also histological findings of the liver, kidney, brain and the change of Tau immunoreactive neurons in hippocampus were observed. Results CF I and CF II showed significant improvement in corner turn test, hole board test, radial arm maze test, passive avoidance test, Acetylcholine (ACh) activity, Acetylcholinesterase (AChE) activity, the serum of Vascular endothelial growth factor (VEGF) protein level and the change of Tau immunoreactive neurons in hippocampus. CF I showed more significant effect than CF II in these tests. However in histological observations of the liver and kidney both CF I and CF II showed glomerular injury and hepatotoxicity. Conclusions These results suggest that Cannabis Fructus was helpful in improving exercise capacity and cognitive function on Chronic hypoperfusion induced Vascular Dementia rats. However Cannabis Fructus affects the liver and kidney, therefore suggest that this is an area for further study.

• The Korean Journal of Rehabilitation Nursing
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• v.5 no.2
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• pp.156-165
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• 2002

The objective of this study was to apply a dementia prevention program to the subjects who were suspected of dementia and test its effect. This study was one group pretest-posttest design. The dementia prevention program was applied for 20 weeks to the 19 subjects who were suspected of dementia after a screen test among 638 subjects enrolled in 10 senior citizen's centers in G city. The scores of self-efficacy, cognition, quality of life were measured before and after the program. The data collected were analyzed using a SPSS (statistical analysis system) program, and frequencies, averages and standard deviations were obtained. The differences of the scores of the pretest and posttest were analyzed with Mann-Whitney test and sign test. The results were as follows: 1. After the program, the average score of self-efficacy was increased from 75.31 (standard deviation 11.99) to 84.26 (standard deviation 13.92). 2. There are no differences between the average scores of physical and psychological quality of life, however, the average score of social quality of life was slightly increased from 2.25 (standard deviation 0.40) to 2.53 (standard deviation 0.43), and the overall score of social quality of life was low. 3. The average score of cognition was significantly increased from 21.00 (standard deviation 2.60) to 24.58 (standard deviation 3.37), thus, it was found that the program was effective to improve the cognition level. 4. The score differences of self-efficacy, quality of life, cognition between the pretest and posttest were statistically significant. 5. The score differences of quality of life between the pretest and posttest were found to be dependent on marital status, exercise and regular checkup yes or no. In conclusion, the program was effective to prevent the subjects suspected of dementia from dementia.

• Journal of The Korean Society of Integrative Medicine
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• v.4 no.3
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• pp.49-59
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• 2016

Purpose : The study was aimed to evaluate the improvement of cognitive and hand functions after the application of a complex rehabilitation intervention program on patients with mild cognitive impairment (MCI) and dementia who were living a regional community from. Methods : Subjects who were living in a regional sanatorium or who were outpatients of a community health center were enrolled from 2012. 2 to 2013.2 All subjects were enforced 8 cycles of a complex rehabilitation intervention program including RON dance, physical activity using therabands, reality awareness training, space retrieval training and handicraft activities. Results : There were significant improvement in LOTCA-G cognitive function and JTHFT hand function test after the application of a complex rehabilitation intervention program. Conclusion : The result shows a significant improvement in cognitive and hand functions after the application of a complex rehabilitation intervention program in patients with MCI and dementia. Therefore the authors suggest the vast studies of the cognitive function program development and hand function vitalization by the application of a complex rehabilitation intervention program.

• Journal of Music and Human Behavior
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• v.2 no.2
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• pp.57-67
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• 2005

Most of stroke patients have not only physical difficulty but speech and neurological disorder because of hemiplegia and such unexpected changes cause psychologic disadaptability and absent-mindedness. Particularly, lowering of physical ability can lead to serious emotional problem from failure or frustration in daily life. Generally, treatment of patient with stroke put emphasis on physical rehabilitation but actually this patient had considerable speech disorder such as aphasia or articulation disorder. Moreover, failing of recognition function, mental disorder as hypochondria, and even visual and auditory disorder are represented. So it is effective to integrate verbal remediation and other treatments in medical care environment. In particular, patients with language disorder very often wither psychologically therefore it is efficient to use of music therapy that gives opulent emotion to aphasia patients. And primarily to investigate the effects of 10 sessions treatments; change in spoken total number of syllables, to confirm their own value by success of given task and reassure about themselves ability. All of 10 sessions stages were scored by MIT manual and its improvement were measured, that is, accomplishment was analyzed within each level in order to prove detail change of spoken total number of syllables. The result of this program organized from 2 syllables to 4 syllables is summarized as follows. Subject A completed in preliminary stage Level I, in 2 syllables case advanced to Level III in fifth session and to Level IV in seventh session, in 3 syllables case advanced to Level III in seventh session and to Level IV in ninth session, and in 4 syllables case showed 8% low success rate in first session but after repeated practice increased considerably in sixth session and in advanced to Level III in eighth session to Level IV in tenth session. Subject B also completed in preliminary stage Level I, in 2 syllables case advanced to Level III in forth session and to Level IV in sixth session, in 3 syllables case advanced to Level III in fifth session and to Level IV in seventh session, and in 4 syllables case showed 10% low success rate in first session and increased considerably in fifth session and in advanced to Level III in seventh session but could not reach to Level IV until tenth session. As a result, it was shown that music therapy using MIT was not statistically meaningful but improved spoken total number of syllables and success rate of task had improved as a whole. Therefore, music intervention using MIT it has positive affect on verbal ability of patients with Broca's Aphasia and their language rehabilitation.

• Journal of Digital Convergence
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• v.16 no.7
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• pp.299-308
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• 2018

This study was conducted to examine the mediating effect of executive function deficiencies on the relationship between smartphone addiction and memory impairment and to suggest treatment implications for adults with smartphone addiction symptoms. For this study, 300 adults(146 males and 154 females) were conducted smartphone addiction scale, Barkley Deficits in Executive Functioning Scale-Short Form(BDEFS-SF), and Multifactorial Memory Questionnaire(MMQ). The results are as follows. First, correlation analyses showed that smartphone addiction, executive function deficiencies, and memory impairment were positively correlated. Second, Smartphone addiction group showed significantly higher scores on all of the subfactors of executive function and memory impairment. Third, Stepwise regression analyses revealed that self-organization/problem solving, self-management to time, self-restraint, and withdrawal were the best predictors of memory impairment. Forth, Executive function deficiencies fully mediated the relationship between smartphone addiction and memory impairment. These findings were considered to suggest that treatment programs for smartphone addiction group needed to include training for cognitive improvement such as executive function rehabilitation.

• Journal of Society of Occupational Therapy for the Aged and Dementia
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• v.12 no.2
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• pp.29-35
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• 2018

Objective : The purpose of this study is to investigate the effects of hand dexterity, cognition skill, instrumental activities of daily living, and depression after cognition improvement activities in elderly welfare centers. Method : The cognition improvement activities were performed for 10 ristimes on 20 elderly people. This study assessed hand dexterity, cognition skills, IADL, and depression using grooved pegboard, MOCA-K, K-IADL, and K-GDS before and after cognition improvement activities. Result : After cognition improvement activities, hand dexterity improves positively and cognition skills and depression improves significantly. However, instrument activities of daily living was not affected by cognition improvement activities. Conclusion : The cognition improvement activities affect positively on hand dexterity, cognition skills and depression. The elderly people of welfare center were highly satisfied with cognition improvement activities. However, this study were held in one welfare center in K city, so further study required to recruit more sample size and develop regional programs to generalize the result.

• Journal of the Korean Society of Physical Medicine
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• v.17 no.4
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• pp.75-83
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• 2022

PURPOSE: This study was conducted to find out the effects of neurocognitive rehabilitation therapy on the swallowing function and quality of life of stroke patients. METHODS: Thirty patients were selected and randomly allocated into an experimental and a control group. Patients in the experimental group received 15 minutes of neurocognitive rehabilitation treatment combined with 15 minutes of traditional treatment. For the control group, patients received 30 minutes of traditional dysphasia treatment. The experiments were conducted for 30 minutes a day, five times a week, for four weeks. New VFSS and SWAL-QOL were administrated to evaluate the outcomes. RESULTS: Swallowing functions were significantly improved in the experimental group and the control group (p < .05), but there was no statistically significant difference in pre- and post-interventional swallowing between the groups (p > .05). The quality of life was also significantly improved (p < .05) for both groups, but there was a statistically significant difference between the two groups (p > .05). Third, a correlational analysis between swallowing function and quality of life revealed a moderate correlation between New VFSS and SWAL-QOL (p < .05). CONCLUSION: The results of this study suggest that swallowing therapy through neurocognitive rehabilitation treatment program could be helpful for improving swallowing function and quality of life in stroke patients. Although there was no statistically significant changes from traditional rehabilitation therapy, training in recognizing the senses in the oral cavity and external environment through neurocognitive rehabilitation therapy can be applied as one of the treatment options.

• Therapeutic Science for Rehabilitation
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• v.4 no.2
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• pp.73-83
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• 2015

Objective: The purpose of this study was to examine the effect of the Spaced Retrieval Training (SRT) with Errorless learning on the elderly with Mild Cognitive Impairment (MCI)'s memory, Instrumental Activities Daily Living, Depression symptom. Methods: A single subject experimental research with ABA design was conducted in this study on the 78-years-old person who was enrolled in day-care center. The total experimental sessions were 16 which composed of 3 sessions for baseline, 10 sessions for intervention and 3 sessions for second baseline. K-Auditory Verbal Learning Test (K-AVLT) was measured for the memory each session. For the measurement of cognitive function, IADL, depression Symptom, Korean version of Montreal Cognitive Assessment (MoCA-K), Philadelphia Geriatric Center Instrumental Activities Daily Living (PGC IADL), Geriatric Depression Scale Korean Version (GDS-K) was measured at pre-post test. Results: Memory at the phase B was improved than Phase A. At the phase B, the scores trend was ascending, but after the intervention at the phase A', the scores trend was descending. The scores of MoCA-K were improved, PGC IADL were maintained, GDS-K were decreased. Conclusion: This results support the evidence of the SRT with EL on the elderly with MCI in the clinical setting. In the future, the correlation researches about MCI's memory and other functional factors will be needed for effective occupational therapy service.

• Therapeutic Science for Rehabilitation
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• v.10 no.2
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• pp.7-22
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• 2021

Objective : This study aimed to analyze the effect of transcranial direct current stimulation (tDCS) on cognitive function recovery in patients with stroke. Methods : Data published in Korean and foreign academic journals from 2009 to 2019 were searched using the NDSL, RISS, PubMed, and CINAHL databases. A total of 11 experimental research articles were selected based on the inclusion and exclusion criteria. A qualitative assessment was conducted, and a meta-analysis of nine results from seven of the stuides was performed using the Comprehensive Meta-Analysis 3.0 program. Results : Based on the results of the meta-analysis, the attention and memory effect sizes were 0.725 and 0.796, respectively, which were both considered a "medium effect size". Statistically significant changes were observed in both the areas (p<0.05). Conclusion : The results of this study confirmed that tDCS can be useful in the rehabilitation of patients with stroke with limited cognitive function. In addition, the application methods differed, indicating that a formalized tDCS protocol is required.

• Therapeutic Science for Rehabilitation
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• v.1 no.1
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• pp.71-79
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• 2012

Objective : To investigate the correlation between relationship ability and ADL performance ability of patients with TBI. Methods : This study was carried out from March 2012 to April 2012 with 20 patients with TBI. Relationship ability assessed using Relationship Change Scale(RCS), ADL performance ability assessed using Functional Independence Measure(FIM). Results : The RCS showed a high level of correlation with marital status and duration of illness. The RCS showed a high level of correlation with the FIM total score and the FIM cognition area. However the RCS did not show a correlation with the FIM motor area. Conclusions : Functional disability of social cognition is a factor that disturbs rehabilitation after TBI and it has a negative influence on the relationship in ADL. If accurate evaluation and treatment on relationship ability after TBI are carried out side by side from the initial stages of onset, we could expect more patients to improve their social cognition and ADL performance ability.