• YAKHAK HOEJI
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• v.8 no.1
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• pp.6-11
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• 1964

녹용은 인삼과 함께 중국을 위시하여 우리나라에 있어서는 수천년래 소위 보약으로써 상용되고 있다. 녹용의 효능중 본초강목 동의보감등에 기재된 것을 보면 조혈 작용이 있다 하였고 한방에서도 빈혈환자에 진효하다고 인정되고 있다. 오와 그 공동 연구자가 조혈에 관한 지견을 보고한바 있으나 저자는 녹용이 과연 조혈작용이 있는가를 재검토코저 하였다. 건전한 웅성가토(체중 2kg내외)를 사용하여 실험적으로 가토빈혈을 야기시킨 다음 이에 녹용을 투여하여 빈혈생성억제여부및 빈혈의 자연회복경과등을 관찰코저 하여 적혈구수, hemoglobin농도,hematocrit및 reticulocyte등을 측정하였다.

• Proceedings of the Korean Society of Applied Pharmacology
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• 1992.05a
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• pp.21-21
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• 1992

녹용은 한방에서 신경조절 약화, 신체발육부진, 허약체질 등에 사용되는 강장제로서 인삼과 더불어 중요한 약재 중의 하나이지만 아직까지 유효 성분이 밝혀져 있지 않다. 알려진 녹용의 성분으로 collagen, acid mucopolysaccharide, 중성지질, 당지질, ganglioside, 인지질, proteolipid, prostaglandins, estrone, estradiol, cholesterol, its ester, 7-keto-cholesterol, 7$\alpha$-hydroxycholesterol , 7$\beta$-hydroxycholesterol , p-hydroxy-benzaldehyde, uracil, uridine, hypoxanthine, nicotinic acid, creatinine urea 등이 보고되었다. 이와 같은 성분들은 동물조직에서 공통적으로 발견되는 것들로서 녹용의 특이성분이라 부르기 어렵다. 그러나 uracil, uridine, hypoxanthine과 같은 핵산염기 관련 성분은 녹용에 비교적 함량이 많고, 이중에서 hypoxanthine은 monoamine oxidase-B에 대한 저해작용이 있으므로 주목할 필요성이 있다.

• The Hankook-Saengyark Bo
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• no.235
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• pp.2-2
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• 1999

인삼수요 큰폭 증가(수출실적 지난해보다 20$\%$ 증가전망) - 진안 홍삼 홍콩수출(전북인삼조합) - 원예$\cdot$특작 종합자금지원 확대(대상 '최소경영단위 이상 농가'로 완화) - 경기 민통선 지역 인삼 경작지 조성 - 녹용등급 상$\cdot$중$\cdot$하 표기 한약협, 복지부등에 건의

• Journal of Animal Science and Technology
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• v.45 no.5
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• pp.749-758
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• 2003

The velvet antler of Korean sika deer has been used to the important resources for human health care with ginseng in Korea and Chinese. For studying on biological function of deer velvet being recorded in many ancient literatures, this experiment was conducted to evaluate the effects of powdered velvet antler on growth, feed intake, feed efficiency and intestinal organ development in growing and adult Sprague-Dawley Rats. Experiments were designed by adding amount of powdered velvet antler such as control (non- supplementation), powdered velvet antler I (PVA I, recommended dose) and powdered velvet antler II (PVA II, thrice recommended dose). The recommended dose of powdered velvet in this experiment was calculated with metabolic body weight of rats, which based on the recommended amounts for 70 kg of human. The growths of growing and adult rats generally appeared advantage in PVA supplementation. The final body weight of control, PVA I and II were respectively 470${\pm}$39.00g, 478${\pm}$30.33g and 475${\pm}$22.72g in growing rats, and 485${\pm}$38.50g, 521${\pm}$38.67g and 508${\pm}$34.44g in adult rats. The average daily feed intake were not significantly influenced but the feed efficiency ratios (feed/gain) were improved by PVA supplementation. The feed/gain ratios of control, PVA I and II were respectively 5.99, 5.47 and 5.54 in growing rats, and 9.04, 7.73 and 8.18 in adult rats. In case of developments of liver, heart, kidney and stomach, we obtained favorable results in both PAC I and II, but their results were not significantly different according to amount of PVA supplementation. Because liver and heart are important organs in the circulation of blood, their favorable effects suggest that velvet antler may have factors contributing hematopoiesis. Conclusively, supplementation of powdered velvet antler resulted in an improved growth, feed efficiency and development of some intestinal organs in growing and adult rat. Even if further investigation of dose in human health care are should be performed, this experiment appeared the best desirable results in PVA I, recommended dose of powdered velvet antler.

• Journal of Ginseng Culture
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• v.4
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• pp.103-127
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• 2022

The influx of modern culture in the early 20th century in Korea led to numerous changes in the country's ginseng industry. With the development of ginseng cultivation technology and commerce, the production and consumption of ginseng increased, and various ginseng products were developed using modern manufacturing technology. Consequently, competition for the sales of these products became fierce. At that time, newspaper advertisements showed detailed trends in the development and sales competition of ginseng products. Before 1920, however, there were few advertisements of ginseng in newspapers. This is thought to be because newspapers had not yet been generalized, and the ginseng industry had not developed that much. Ginseng advertisements started to revitalize in the early 1920s after the launch of the Korean daily newspapers Dong-A Ilbo and Chosun Ilbo. Such advertisements in this period focused on emphasizing the traditional efficacy of Oriental medicine and the mysterious effects of ginseng. There were many advertisements for products that prescribed the combination of ginseng and deer antler, indicating the great popularity of this prescription at the time. Furthermore, advertisements showed many personal experience stories about taking such products. Mail order and telemarketing sales were already widely used in the 1920s . In 1925, there were advertisements that ginseng products were delivered every day. The advertisements revealed that ginseng roots were classified more elaborately than they are now according to size and quality. Ginseng products in the 1920s did not deviate significantly from the scope of traditional Oriental medicine formulations such as liquid medicine, pill, and concentrated extract. In the 1930s, ginseng advertisements became more active. At this time, experts such as university professors and doctors in medicine or in pharmacy appeared in the advertisements. They recommended ginseng products or explained the ingredients and medicinal effects of the products. Even their experimental notes based on scientific research results appeared in the advertisements to enhance the reliability of the ginseng products. In 1931, modern tablet advertisements appeared. Ginseng products supplemented with vitamins and other specific ingredients as well as ginseng thin rice gruel for the sick appeared at this time. In 1938, ginseng advertisements became more popular, and advertisements using talents as models, such as dancer Choi Seunghee or famous movie stars, models appeared. Ginseng advertisements in the 1920s and 1930s clearly show a side of our rapidly changing society at the time.

• 대한한약신문
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• s.115
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• pp.1-12
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• 2006

'한약부작용의 실상' 책자 관련 대책방안 논의/"한약 간동성 없다" 임상연구 결과 발표/초대 '한의학정책연구원' 변철식 원장 취임/의료비 소득공제 증빙자료제출 요청에 따른 건의/의료계, '전체 수납내역 제출'에 반발/통계청 '한국표준직업분류' 개정에 따른 의견서 제출/백강잠, 파극천 등 6개 품목 품질기준 강화/"한약재 '양제근' 투여로 아토피 피부염 치료"/한의사협회, 한의학 폄하 강력 대응/한약재 4품목, 품질부적합 판정 사용 중지/무면호 의료.조제행위 단속 시민 포상제 강화/복지부, 한의학 세계브랜드 적극 추진/WHO, 경혈위치 국제 표준안 확정/1km내 약국.의료기관 '동일명칭 사용' 논란/의협, 연말정산 간소화 방안 헌법소원/약국가, 비급여 품목 자료제출 '자포자기'/박재완 의원 "녹용 과학적 기준 검증방법 필요"/2007년부터 인삼제품에 새로운 농약기준 마련/뇌졸증 치료, 양방 59% 한방 41%/"전통의학, 양학과 결합.표준화 시급"/"100처방 발목, 유일무이한 면허권 제한"/개성공단 협력병원에 한의사 파견/지부탐방-지부장에게 듣는다/평간순기보중환 이야기/명칭이 비슷하여 감별하기 어려운 한약재/우리약초를 찾아서-오미자/한방과 항문질환/백부자의 진.위품 감별에 대한 소고

• Journal of Pharmacopuncture
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• v.3 no.2
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• pp.131-152
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• 2000

The effects of Cervus elaphus aquapuncuture and Ginseng Radix aquapuncuture on the growth, protein efficiency ratio, contents of total protein, total cholesterol, and triglyceride in serum were studied for thirty four days. The results were summarized as follows. 1. Weight significantly increased in $0.3\%$ Cervus elaphus aquapuncture group on Chunchu loci and in $0.2\%$ Ginseng Radix aquapuncture group on Chunchu loci compared to normal saline aquapuncture group on Chunchu loci. 2. Protein efficiency ratio significantly increased in $0.2\%$ and $0.3\%$ of Cervus elaphus aquapuncture group on Chunchu loci and $0.1\%$, $0.2\%$ and $0.3\%$ of Ginseng Radix aquapuncture group on Chunchu loci compared to nonnal saline aquapuncture on Chunchu loci. 3. Total protein significantly increased in $0.2\%$ and $0.3\%$ of Cervus elaphus aquapuncture group on Chunchu loci compared to nonnal saline aqriapuncture On Chunchu loci. whereas it had a tendency to increase in $0.2\%$ Ginseng Radix aquapuncture group on Chunchu loci compared to normal saline aquapuncture group on Chunchu loci. 4. Total cholesterol increased a little in $0.3\%$ Cervus elaphus aquapuncture group on Chunchu loci compared to normal saline aquapuncture group on Chunchu loci. 5. Triglyceride significantly increased in $0.2\%$ Ginseng Radix aqua puncture group on Chunchu loci compared to normal saline aquapuncture group on Chunchu loci. Significance was acknowledged in the effect by density difference of medicines. In the Cervus elaphus group, there was the most significant increase in density of $0.3\%$ aquapuncture, whereas in Ginseng Radix group, there was the most significant increase in density of $0.2\%$ aquapuncture. So setting up density of medicines is important and many various studies for clinical application are required.

• THE JOURNAL OF KOREAN ORIENTAL ONCOLOGY
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• v.4 no.1
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• pp.37-53
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• 1998

The sprig of Jinryungtang Gagambang has been used for curing as a traditional medicine without any experimental evidence to support the rational basis for their clinical use. This experiment was carried out to evaluate the possible therapeutic or antitumoral effects of Jinryungtang Gagambang extract against cancer, and to study some mechanisms responsible for its effect. The cytotoxic and antitumor effects were evaluated on human cell liens (A549, hep3B, Caki-1, Sarcoma 180) after exposure to Jinryungtang Gagambang extract using in ILS, colony forming efficency and SRB assay which were regarded as a valuable method for cytotoxic and antitumor effects of unknown compound on tumor cell lines. The results obtained in this studies were as follows. 1. As a result of exposure to Jinryungtang Gagambang extract, the proliferation of A549, hep3B, Caki-1, good correlations were shown from the results of SRB assay and those of clogenetic assay. 2. The oral administration of Jinryungtang Gagambang extract showed significant effects of increase of MST(mean survival time) and ILS(increased life span) depending on the increasing concentration. 3. Against squamous cell carcinoma induced by MCA, Jinryungtang Gagambang decreased not only the frequency of tumor production but also the number and weight of tumors per tumor bearing mice(TBM). Jinryungtang Gagambang also significantly suppressed the development of 3LL cell-implanted tumors by frequency and their size, and some developed tumors were regressed by the continuous treatment of Jinryungtang Gagambang extract into TBM. 4. Jinryungtang Gagambang extract also increased NK cell activities. According to the above results, it could be suggested that Jinryungtang Gagambang extract has prominent antiutmor effect.