• Radiation Oncology Journal
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• v.17 no.4
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• pp.275-280
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• 1999

Purpose : To assess the feasibility and the toxicity of the neoadjuvant chemotherapy on the treatment of patients with locoregionally advanced nasopharyngeal carcinoma. Methods and Materials : We analyzed 77 previously untreated and histologically confirmed advanced stage nasopharyngeal carcinoma patients treated with neoadjuvant chemotherapy followed by radiation therapy at the Seoul National University Hospital between 1984 and 1996. The stage distribution was as follows : AJCC stage III-2, stage IV-75. Sixty-six patients received infusion of 5-FU (1000 mg/m$^2$, on Day 1$\~$5) and cisplatin (100 mg/m$^2$, on Day 1), eleven patients received infusion of 5-FU (1000 mg/m$^2$, on Day 1 $\~$5) and carboplatin (300 mg/m$^2$, on Day 1) as neoadjuvant chemotherapy Prior to radiation therapy. The median follow-up for surviving patients was 44 months. Results : The overall chemotherapy response rates were 87$\%$. The toxicities of chemotherapy were mild. Only 3 patients experienced Grade 3 toxicities (1 for cytopenia, 2 for nause/vomiting). The degree of radiation induced mucositis was not severe, and ten patients developed Grade 2 mucositis. The 5-year overall survival rates were 68$\%$ and the 5-year disease free survival rates were 65$\%$. The 5-year freedom from distant metastasis rates were 82$\%$ and 5-year locoregional control rates were 75$\%$. Conclusion : This single institution experience suggests that neoadjuvant chemotherapy improves overall survival and disease free survival for patients with advanced stage nasopharyngeal carcinoma without increase of toxicity.

• The korean journal of orthodontics
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• v.30 no.6 s.83
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• pp.699-712
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• 2000

Reduced nasal breathing can influence the growth at)d development of facial structures. It nay have many causes, and enlarged adenoid is the most frequent one. To investigate the effects of adenoids to jaw growth, we must first understand the normal growth of adenoids and jaws, and the relationship between size of adenoids and the values lot the jaw variables. The purpose of this study is to present a more objective standard of nasopharyngeal size and jaw dimension at each bone age, by using Cervical Vertebrae Maturation Index(CYMI) of Hassel, from normal occlusion children aged 6 to 17. The results of this study suggests as follows : 1. At same bone age, female's chronologic age was about 2 year older than male. 2. There was a growth peak of nasopharyngeal(NP) height and depth between CVMI 1 to 2 in male, hut in female NP height and depth gradually increase through CVMI 1 to 6. 3. Relative airway of nasopharynx increases the most between CVMI 1 to 2 period in both gender 4. Among adenoid measurements, Ad2-related variables and upper pharynx, and among dentofacial measurements inter canine width in both arch, maxillary intermolar width and palatal depth had high correlation coefficient with adenoid percentage.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.2
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• pp.325-333
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• 2016

This paper proposes controller design algorithms for a ceramic soldering iron temperature control system, and reports their effectiveness in a control experiment. Because the responses of the ceramic soldering iron temperature to the control input are non-linear and very slow, precise modeling and controller design is difficult. In this study, the temperature characteristics of a ceramic soldering iron are represented by TSK fuzzy models consisting of TSK fuzzy rules. In the fuzzy rules, the premise variable is the control input and the consequences are the transfer functions. The transfer functions in the fuzzy model were obtained from the step input responses. As the responses of the ceramic soldering iron temperature are very slow, it is difficult to obtain the complete step input responses. This paper proposes a genetic algorithm to obtain the transfer functions from an incomplete step input responses, and showed its effectiveness in examples. This paper also reports a fuzzy controller design method from the TSK fuzzy model and examples. The proposed methods were applied to the temperature control experiments of ceramic iron. The TSK fuzzy model consisted of 7 TSK fuzzy rules, and the consequences were PI controllers. The experimental results of the proposed fuzzy PI controller were superior to the linear controller and were as good as in previous studies using a fuzzy PID controller.

• Conservation Science in Museum
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• v.14
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• pp.23-28
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• 2013

This paper aimed to show the whole conservation process of the human shaped terra cotta mask that was excavated from one of construction sites at Jungcheon-ri, Geumsan-myeon, Jinju. This mask was X-rayed to get the correct making techniques and there are 4 holes on the top of the head and each diameter of the 3 holes is exact and the other hole is different from the three. The long and sharp shape of the nose is in trapezoid which was separately made with clay and put on (the face). It's found that there are round grooves each around upper and down lips. (upper in length: 10mm, down in length: 6 mm). All restoring materials and adhesives used for restoration to associate each piece are reversibility materials. According to a few points on buried bones of animals distributed around the sites, holes and grooves on the top of the head, ears and teeth to wear something, it academically presumes that this mask could be possibly used for the group ritual. Especially, the whole procedure from excavation to scientific conservation process resulted to have a special exhibition to give the public new eyes how the exhibition realizes to the public.

• Pediatric Infection and Vaccine
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• v.9 no.1
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• pp.74-78
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• 2002

Purpose : Proper diagnosis of group A streptococcal pharyngitis that may cause chronic diseases in childhood is not easy because its signs and symptoms would be nonspecific. Because results of classical throat culture delays for one to two days, we'd like to determine whether early antibiotics would be introduced with according to the clinical score system. This study was undertaken to evaluate of clinical usefulness of scoring system based on the clinical and laboratory findings. Methods : From Jan. 1998 to Dec. 2000, 10 clinical items based on modified 9 items by Breese in 1977 were checked in patients with pharyngitis who visited on outpatients clinic of pediatrics, Kyunghee University Hospital. We compared the results of throat culture with the points of clinical score system. Results : Out of 45 cases, the positive culture for Group A Streptococcus was 20 and negative culture was 25. When we applied more than 30 points of score, which correspond to 70 percentile of study population, the sensitivity and specificity were 35.0% and 96.0%, respectively. Conclusion : Although sensitivity was relatively low this scoring system, but the high specificity may be useful diagnostic tool in the areas where the rate of isolation of Group A Streptococcus is low.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.11 no.2
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• pp.116-121
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• 2008

Purpose: Cricopharyngeal incoordination is a rare cause of swallowing difficulties in newborns and infants; it is characterized by delayed pharyngeal contractions related to cricopharyngeal relaxation. Dysphagia and repeated aspiration are common findings despite normal sucking. We conducted this study to assess the clinical features of cricopharyngeal incoordination in newborns and infants. Methods: An analysis of the clinical data from 17 patients with cricopharyngeal incoordination who were admitted to the Department of Pediatrics, Pusan National University Hospital, between 2000 and 2006 was conducted retrospectively. The diagnosis of cricopharyngeal incoordination was established by the clinical characteristics and the videofluoroscopic swallowing studies. Results: The male to female ratio was 1:1.1 (males 8, females 9) the age range 1 to 60 days. The body weight of 11 patients (64.7%) was less than the $10^{th}$ percentile at diagnosis. Six patients (35.3%) were born prematurely. The associated anomalies or diseases were chromosomal anomaly (2 cases), congenital heart disease (3 cases), and laryngomalacia, hypoxic brain damage or neonatal seizures (1 case each). The chief complaints of patients were recurrent aspiration pneumonia (10 cases), feeding difficulty (9 cases), dyspnea (4 cases), and chocking (4 cases). The severity of aspiration on the videoesophagogram or esophagogram was mild in 12 cases. The correlation between the severity of aspiration and the duration of tube feeding after the diagnosis was significant (p<0.05). Conclusion: Cricopharyngeal incoordination should be considered in the differential diagnosis of newborns and infants, without known risk factors associated with swallowing dysfunction, when they present with unexplained respiratory problems. Although the prognosis of cricopharyngeal incoordination is good, early diagnosis and tube feeding are recommended to prevent the complications associated with this disorder.

• Proceedings of the KOR-BRONCHOESO Conference
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• 2001.12a
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• pp.23-23
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• 2001

• Proceedings of the KOR-BRONCHOESO Conference
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• 2001.12a
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• pp.3-6
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• 2001

• Journal of The Korean Radiological Technologist Association
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• v.25 no.1
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• pp.44-45
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• 1999

• Proceedings of the Korean Society of Radiological Science
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• 1999.10a
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• pp.77-77
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• 1999