• Title/Summary/Keyword: 인공수축

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Effects of the Artificial Shrinkage and Assisted Hatching Before Vitrification on the Development of the Vitrified Mouse Expanding Blastocysts (유리화동결 전 인공수축과 보조부화술이 융해 후 생쥐 포배아의 발달에 미치는 영향)

  • Jo, Deok-Hyeon;Ko, Gyoung-Rae;Jung, Ji-Hye;Choi, Jong-Ryeol;Joo, Jong-Kil;Lee, Kyu-Sup
    • Clinical and Experimental Reproductive Medicine
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    • v.35 no.4
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    • pp.275-283
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    • 2008
  • Objective: This study was conducted to investigate the effects of the artificial shrinkage and assisted hatching (PZD; patial zona dissetion) before vitrification on the development of vitrified mouse expanding blastocyst. Methods: Mouse 2-cell embryos were collected and cultured in G1.1 and G2.2 to expanding blastocyst. For artificial shrinkage (AS) the micro injection pipette was inserted into blastocoele cavity and blastocoele fluid was aspirated. For assisted hatching (AH) PZD method was used. Control group was -AS/-AH and treatment groups were -AS/+AH, +AS/-AH and +AS/+AH. After AS and AH mouse blastocysts were equillibrated in G10 and G10E20 for 3 mins, respectively, and vitrified in G25E25 after loading on capped pulled-straw. Vitrified mouse blastocysts were thawed and cultured for 24 hrs. The survival and hatching rate was compared among one control and three treatment groups. Results: The survival rates were 99%, 92% in +AS/+AH and +AS/-AH groups and 54%, 58% in -AS/-AH and -AS/+AH group, respectively. The survival rate was significantly higher in +AS group than in -AS group (p<0.01). Hatching rates were 34%, 96% in -AS/-AH and -AS/+AH groups and 41%, 100% in +AS/-AH and +AS/+AH, respectively. The hatching rates was higher in +AH group than in -AH group (p<0.01). After thawing recovery rates were 100%. Loading on capped pulled-straw, that is effective and useful method on vitrification. Conclusion: This study showed that artificial shrinkage of blastocoele cavity and assisted hatching (PZD) significantly improved the development of the vitrified mouse expanding blastocysts.

A Study of Shrinkage Depend on Depth of Artificial Lightweight Aggregate Concrete (인공경량 콘크리트의 깊이에 따른 수축에 관한 연구)

  • Lee, Chang-Soo;Lin, Yan
    • Proceedings of the Korea Concrete Institute Conference
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    • 2010.05a
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    • pp.271-272
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    • 2010
  • This thesis is researched to compare the shrinkage of lightweight concrete depending on depth to normal concrete. It is used artificial lightweight aggregate which has 20% of pre-absorb value by lightweight concrete. When water-binder ratio is 30%, average shrinkage of lightweight concrete section decreased than normal concrete, but differential shrinkage of lightweight concrete section increased. However water-binder ratio is 40%, average shrinkage and differential shrinkage of lightweight concrete section decreased than normal concrete.

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Performance Evaluation for Dry Shrinkage of Dry Mortar Using Artificial Aggregate Made from Circulating Fludized Bed Combution Ash and Modified CaO Type Expansive Admixture (개질 CaO 팽창재 활용 CFBC 인공잔골재 건조 모르타르의 건조수축 성능평가에 관한 연구)

  • Park, Ji-Sun;Song, Tae-Hyeob
    • Journal of the Korean Recycled Construction Resources Institute
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    • v.6 no.4
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    • pp.331-335
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    • 2018
  • The purpose of this study is to investigate the feasibility of CFBC artificial fine aggregate as a substitute for natural aggregate used in dry mortar. The basic performance of the flow, compressive strength and dry shrinkage of the dry mortar was evaluated. Four types of test dry mortar specimens using natural aggregate without expansion admixture, a specimen with modified CaO expansion admixture and natural aggregate, a specimen with modified CaO expansion admixture and CFBC artificial fine aggregate, and a specimen using CFBC artificial fine aggregate without modified CaO expansion admixture were evaluated respectively. As a result of evaluation of drying shrinkage performance at 20th day of age, the dry shrinkage performance of the specimen using modified CaO expansion admixture was found to be the highest at $250{\times}10^{-6}$. On the other hand, the specimen containing the modified CaO expansion admixture with CFBC artificial aggregate exhibited a shrinkage of $410{\times}10^{-6}$, and the drying shrinkage of specimen using natural fine aggregate without expansion admixture was $450{\times}10^{-6}$. When the modified CaO expansion material was used, and exhibited performance equal to or higher than that of the shrinkage-drying property.

The Characteristics of Compressive Strength in Mortar with Internal Curing According to Curing Condition (내부양생을 적용한 모르타르의 양생조건에 따른 압축강도 특성)

  • Kim, Joo-Hyung;Cho, Young-Keun;Lee, Kwang-Myong
    • Journal of the Korean Recycled Construction Resources Institute
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    • v.6 no.2
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    • pp.87-93
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    • 2018
  • The use of high-strength concrete in construction have been increasing steadily. However, high-strength concrete has a low water-binder ratio, and the problems such as cracks due to hydration heat and shrinkage during the hydration process at the early age. Recently, as a method to reduce the shrinkage of concrete, study of internal curing has carried out according to increasing about interest about it. In this study, the effect of compressive strength on the curing condition(drying, moist, water) was investigated by using artificial lightweight aggregate(LWA) in high strength and high volume mortar. As a result of autogenous shrinkage, the effect of shrinkage reduction was enhanced depending on the increasing of LWA replacement. According to the curing condition, the results of compressive strength showed the different trend. The compressive strength has increased on the drying and moisture condition and decreased on the water condition.

A Study on Elongation/Contraction Behavior and Mechanical Properties of Oxy-Polyacrylonitrile(PAN) Fiber in Basic/Acidic Solution for Artificial Muscle Applications (산화된 폴리아크릴로니트릴 섬유의 인공근육 응용을 위한 염기/산 용액에서의 신장/수축 거동과 기계적 특성 연구)

  • 이영관;김상완;이경섭;조인희;이주화
    • Polymer(Korea)
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    • v.26 no.4
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    • pp.468-476
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    • 2002
  • Oxy-PAN fiber prepared from the preoxidation and saponification of raw PAN fiber is known to elongate and contract when immersed in basic and acidic solutions, respectively. In this study, about 30% elongation in NaOH solution and 30∼50% contraction in HCl solution have been observed. In mechanical test, the mechanical properties of oxy-PAN fiber in the contracted state was stronger than that in the elongated state. These behaviors and mechanical properties are compared to those of living muscle and linear actuator. The change of length in NaOH and HCl solutions is due to switching between a hydrophilic and a hydrophobic structure. Other reasons are exchange of ion and water in/out of oxy-PAN fiber, and osmotic pressure difference associated with relevant ions. Much studies are needed to clarify the effective factors on but the oxy-PAN fiber's elongation/contraction behavior and mechanical properties, but the oxy-PAN fiber perpared in our laboratory has a sufficient potential for application as artificial muscle and linear actuator.

심혈관 시뮬레이션 데이터 기반의 심혈관 혈류역학 예측용 인공지능 개발

  • Lee, Gyeong-Eun;Kim, Jung-Jae;Lee, Seo-Ho;Sin, Seong-Ung;Bang, Hyeon-Gi;Kim, Gi-Tae;Ryu, A-Jin;Lee, Jong-Ho;Kim, Gi-Tae;Park, Seon-Yeol;Lee, Yeong-Gwon;Sim, Eun-Bo
    • Proceeding of EDISON Challenge
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    • 2017.03a
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    • pp.712-714
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    • 2017
  • 미병의 예방과 관리의 중요성이 거론되고 있으나, 미병에 대한 분류나 진단을 위한 확고한 근거가 미약한 상황으로서 미병 진단 인자 분류를 위한 생리시스템 모델 개발이 필요한 시점이다. 본 연구의 목적은 개발한 생리학적 모델이 미병 단계를 구별하는데 효과 및 유용성이 있는지를 임상 검증하기 위하여 생리학적 모델 인공지능 시뮬레이션을 개발하고자 함이다. 인공지능 계산은 3층으로 구성된 네트워크를 이용하였으며 각 층은 30개의 neuron들로 구성하였다. 인공지능망의 입력 값은 나이, 수축기 혈압, 이완기 혈압, 심박수 값 (입력 값 4개)이고 출력 값은 혈관 저항값인 Ra이다. 머신러닝 차수를 높이면서 인공지능을 사용하지 않은 생리적 모델로부터 도출된 결과와 인공지능을 통하여 계산된 결과를 비교하였다. 개발된 인공지능계산을 이용한 생리시스템 모델은 대량의 표본집단에서 임상 검증에 기여할 것이다.

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An Experimental Study on the Drying Shrinkage and Creep of High Strength Eco Lightweight Aggregate Concrete (고강도 에코인공경량골재콘크리트의 건조수축 및 크리프에 관한 실험적 연구)

  • Lee, Jin-Woo;Park, Hee-Gon;Kim, Woo-Jae;Bae, Yeoun-Ki;Lee, Hyoung-Woo;Lee, Jae-Sam
    • Proceedings of the Korea Concrete Institute Conference
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    • 2008.04a
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    • pp.425-428
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    • 2008
  • To use lightweight aggregate concrete with the structural material, it was need to evaluate property of mechanic and drying shrinkage and creep of the lightweight aggregate concrete, but these weren't. So the purpose of this study which it sees follows the mechanical property of the eco lightweight aggregate concrete according to the water binder ration in the high strength concrete. Eco lightweight aggregate was made with clay and crushed rock in this study. To make experiment, water binder ratio was divided 35% and 39%. And the fresh concrete properties were that slump flow was 500${\pm}$50mm, air contents was 2.0${\pm}$1.0%. It evaluated the hold a drying shrinkage and the creep the effect, it analyzed quality and reliability of the eco lightweight aggregate concrete.

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Numerical Analysis of the Blood Flow in the Korean Artificial Heart Using Two Dimensional Model (2차원 모델을 이용한 한국형 인공심장 내 혈액 유동에 대한 수치적 해석)

  • 박명수;심은보;고형종;사종엽;박찬영;민병구
    • Journal of Biomedical Engineering Research
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    • v.24 no.4
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    • pp.301-307
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    • 2003
  • In this study, we Presented computational results on the blood flow in the sac of the Korean artificial heart. Two dimensional unsteady flow was assumed and we utilized a finite element commercial code ADINA to simulate the blood flow. Rigid body-solid contact were considered between the actuator and the blood sac and fluid-structure interaction between the blood and the sac. The three geometric models proposed in the design process were simulated to assess the hemodynamic characteristics of the models According to the computational results, a strong flow to the outlet and a stagnated flow region near the inlet were observed during systole. The sac was filled with blood and recirculating flow was generated near the outlet during diastole. Shear stress during systole had its extreme values near the outlet edge whereas the magnitude of shear stress values were relative)v high near the inlet edge and the contacting surface with the actuator.

Artificial intelligence-based blood pressure prediction using photoplethysmography signals

  • Yonghee Lee;YongWan Ju;Jundong Lee
    • Journal of the Korea Society of Computer and Information
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    • v.28 no.11
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    • pp.155-160
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    • 2023
  • This paper presents a method for predicting blood pressure using the photoplethysmography signals. First, after measuring the optical blood flow signal, artifacts are removed through a preprocessing process, and a signal for learning is obtained. In addition, weight and height, which affect blood pressure, are measured as additional information. Next, a system is built to estimate systolic and diastolic blood pressure by learning the photoplethysmography signals, height, and weight as input variables through an artificial intelligence algorithm. The constructed system predicts the systolic and diastolic blood pressures using the inputs. The proposed method can continuously predict blood pressure in real time by receiving photoplethysmography signals that reflect the state of the heart and blood vessels, and the height and weight of the subject in an unconstrained method. In order to confirm the usefulness of the artificial intelligence-based blood pressure prediction system presented in this study, the usefulness of the results is verified by comparing the measured blood pressure with the predicted blood pressure.