• Journal of Chest Surgery
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• v.40 no.7 s.276
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• pp.512-516
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• 2007

A mechanical circulatory support system is a life-saving option for treating acute severe respiratory failure or cardiac failure. There are currently a few types of assist devices and the Twin-Pulse Life Support (T-PLS) system is a kind of pulsatile pump. We report here on three patients with severe life threatening cardiopulmonary dysfunction who had the T-PLS system used as an assist device. The indications for applying the T-PLS system were continuing respiratory or cardiac failure in spite of maximal ventilatory and inotropic support. There were two patients with acute respiratory failure due to infection and one patient with cardiac failure due to acute myocarditis. One respiratory failure patient and one cardiac failure patient survived after applying the T-PLS system for 3 days and 5 days, respectively. The T-PLS system is useful as an assist device and it should be considered before multi-organ failure occurs.

• 순환기질환의공학회:학술대회논문집
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• 2001.11a
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• pp.39-40
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• 2001

• Journal of the Institute of Electronics Engineers of Korea SC
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• v.44 no.1
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• pp.94-99
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• 2007

Many cases of acute cardiac shock and cardiac arrest in emergency room and ICU have been increasing. In this case, ECMO with centrifugal pump has been used generally. However, due to the heavy weight and big size, the system is not adequate for emergency cases. And other defects of this system are that membrane oxygenator's pressure is high and blood are exposed to the air. There was some tries of ECMO using pulsatile pump, but it was found that the weak point of these system is high peak pressure and hemolysis. The mechanism of twin pulsatile pump is that Membrane oxygenator Outlet Pump(MOP) make negative pressure when Membrane oxygenator Inlet Pump(MIP) provides high positive pressure, and the negative pressure will decrease positive pressure of Membrane Oxygenator. Our group analyzed this advantage through In-Vitro and 12 Cases In-Vivo test.

• Proceedings of the KSME Conference
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• 2002.08a
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• pp.723-724
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• 2002

Computational modeling is presented to investigate the hemodynamics of coronary circulation for the cardiac arrest model during the operation of an ECLS called T-PLS. A lumped parameter model is utilized to delineate the hemodynamics of coronary circulation. For verification of the present method, we compute the coronary circulation for normal case and compare those results with the existing data. Numerical results on the cardiac arrest model show that T-PLS can increase LAD flow significantly.

• Journal of the Korean Society of Industry Convergence
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• v.12 no.1
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• pp.27-33
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• 2009

In this paper, a computational analysis using a lumped system model is performed to investigate the hemodynamics of coronary circulation under the operation of T-PLS relevant to the cardiac arrest cases. The coronary circulation system is assumed to be comprised of three compartments: coronary arteries, coronary capillaries, and coronary veins. The effect of myocardial muscle contraction or relaxation is represented by temporal variations in the bias pressure. To verify the present method, we analyzed the coronary circulation for normal case and then compared the results with the existing data. Numerical results on the cardiac arrest model showed that T-PLS can increase LAD flow significantly.