• Korean Journal of Biological Psychiatry
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• v.6 no.2
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• pp.153-160
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• 1999

Animal models can provide a useful tool for the study of some aspects of psychiatric disorders and their treatment. The four criteria for the evaluation of animal models of psychiatric disorders are as following : 1) similarity of inducing conditions 2) similarity of behavioral state 3) common underlying neurobiological mechanisms 4) reversal by clinically effective treatment techniques. Several animal models have been proposed for schizophrenia : phenylethylamine model, L-dopa model, hallucinogen model, cocaine model, amphetamine model, phencyclidine model, noradrenergic reward system lesion model, reticular stimulation model, social isolation model, conditioned avoidance reaction, catalepsy test, paw test, self-stimulation paradigms, latent inhibition paradigms, blocking paradigms, prepulse inhibition of the startle reflex, rodent interaction, social behavior in monkeys, hippocampal damage, high ambient pressure, and models using selective breeding. Among them, animals with bilateral lesion of the hippocampus may provide an adequate animal model for several symptoms of schizophrenia, and ketamine model can reproduce negative symptoms and cognitive deficits as well as positive symptoms of schizophrenia. In conclusion, no model of schizophrenia is entirely representative of the disease, and findings gleaned from model systems must be cautiously interpreted. Furthermore, the process of developing and validating animal models must work in concert with the process to identify reliable measures of human phenomenology.

• Proceedings of the Korean Vacuum Society Conference
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• 1999.07a
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• pp.53-53
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• 1999

전계방출을 이용한 평판 표시장치는 CRT가 가진 장점을 모두 갖는 동시에 얇고 가벼우며 낮은 전력소모로 완벽한 색을 구현할 수 있는 차세대 표시장치로서 이에 대한 여국가 활발히 이루어지고 있다. 여기에 사용되는 음극물질로서 실리콘이나 몰리 등을 팁모양으로 제작하여 사용해 왔다. 하지만 잔류가스에 의한 역스퍼터링이나 화학적 반응에 의해서 전계방출 성능이 점차 저하되는 등의 해결해야할 많은 문제가 있다. 이러한 문제들을 해결하기 위하여 탄소계 재료로서 다이아몬드, 다이아몬드상 카본 등을 이용하려는 노력이 진행되어 왔다. 이중 유리화 비정형 탄소는 다량의 결함을 가지고 있는 유리질의 고상 탄소 재로로서, 전기전도도가 우수하면서 outgassing이 적고 기계적 강도가 뛰어나며 고온에서도 화학적으로 안정하여 전계방출 소자의 음극재료로서 알맞은 것으로 생각된다. 유리화 비정형 탄소가루를 전기영동법으로 기판에 코팅하여 전계방출 소자를 제작하였다. 전기영동 용액으로 이소프로필알코올에 질산마그네슘과 소량의 증류수, 유리화 비정형 탄소분말을 섞어주었고 기판으로는 몰리(Mo)가 증착된 유리를 사용하였다. 균일한 증착을 위해서 증착후 역전압을 걸어 주는 방법과 증착 후 플라즈마 처리를 하는 등의 여러 가지 방법을 사용했다. 전계방출 전류는 1$\times$10-7Torr이사에서 측정하였다. 1회 제작된 용액으로 반복해서 증착한 횟수에 따라 표면의 거치기, 입자의 분포, 전계방출 측정 결과 등의 차이가 관찰되었다. 발광이미지는 전압에 따라 변화하였고, 균일한 발광을 관찰하기 위해서 오랜 시간동안 aging 과정을 거쳐야 했다. 그리고 구 모양의 양극을 사용해서 위치를 변화시키며 시동 전기장을 관찰하여 위치에 따른 전계방출의 차이를 조사하여 발광의 균일성을 알 수 있었다.on microscopy로 분석하였으며 구조 분석은 X-선 회절분석, X-ray photoelectron spectroscopy 그리고Auger electron spectroscope로 하였다. 증착된 산화바나듐 박막의 전기화학적 특성을 분석하기 위하여 리튬 메탈을 anode로 하고 EC:DMC=1:1, 1M LiPF6 액체 전해질을 사용한 Half-Cell를 구성하여 200회 이상의 정전류 충 방전 시험을 행하였다. Half-Cell test 결과 박막의 결정성과 표면상태에 따라 매우 다른 전지 특성을 나타내었다.도상승율을 갖는 경우가 다른 베이킹 시나리오 모델에 비해 효과적이라 생각되며 초대 필요 공급열량은 200kW 정도로 산출되었다. 실질적인 수치를 얻기 위해 보다 고차원 모델로의 해석이 필요하리라 생각된다. 끝으로 장기적인 관점에서 KSTAR 장치의 베이킹 계획도 살펴본다.습파라미터와 더불어, 본 연구에서 새롭게 제시된 주기분할층의 파라미터들이 모형의 학습성과를 높이기 위해 함께 고려된다. 한편, 이러한 학습과정에서 추가적으로 고려해야 할 파라미터 갯수가 증가함에 따라서, 본 모델의 학습성과가 local minimum에 빠지는 문제점이 발생될 수 있다. 즉, 웨이블릿분석과 인공신경망모형을 모두 전역적으로 최적화시켜야 하는 문제가 발생한다. 본 연구에서는 이 문제를 해결하기 위해서, 최근 local minimum의 가능성을 최소화하여 전역적인 학습성과를 높여 주는 인공지능기법으로서 유전자알고리즘기법을 본 연구이 통합모델에 반영하였다. 이에 대한 실증사례 분석결과는 일일 환율예측문제를 적용하였을 경우, 기존의 방법론보다 더 나운 예측성과를 타나내었다.pective" to workflow architectural discussions. The vocabulary suggested

• Journal of Navigation and Port Research
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• v.33 no.10
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• pp.703-707
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• 2009

In order to evaluate applicability of cylindrical slit type block breakwater to the field water, which was designed from the previous physical model study, it is analyzed the calmness of harbor area by the numerical model experiment. For a small fishery port in southern coast of Korea a SWAN model using the wave action balance equation was formulated. The reflection and transmission coefficients induced by the physical model test were introduced to the numerical model. The model response with cylindrical slit type breakwater was compared with the impermeable breakwater case and the possibility of water quality improvement through the water circulation by the new structure was investigated. For numerical simulation, parameters of deepwater design wave from the prediction report II for overall deepwater design wave by KORDI were used and wind parameters from the 50years return period observed for 37years(1970~2006) were adopted in the numerical model. The response of west breakwater in Mijo port applying the NE and NNE waves, which were dominant in this area, was analyzed. It was found that the transmission characteristic of designed cylindrical slit breakwater was well presented in the numerical model.

• Journal of Korea Water Resources Association
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• v.54 no.11
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• pp.985-998
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• 2021

In general, the upstream dam changes downstream flow regime dramatically, i.e., from natural flow regime to hydropeaking flows. This study investigates the impact of the natural flow pattern on downstream fish habitat in a regulated river in Korea using the physical habitat simulation. The study area is a 13.4 km long reach of the Geum-gang River, located downstream from the Yongdam Dam, Korea. A field monitoring revealed that three fish species are dominant, namely Zacco platypus, Coreoleuciscus splendidus, and Opsariichthys bidens, and they account for 70% of the total fish community. Specially, Opsariichthys bidens is an indigenous species in the Geum-gang River. The three fish species are selected as target fish species for the physical habitat simulation. The Nays2D model, a 2D shallow water equation solver, and the HSI (Habitat Suitability Index) model are used for hydraulic and habitat simulations, respectively. To assess the impact of the natural flow pattern, this study uses the annual natural flow regime and hydropeaking flows from the dam. It is found that the natural flow regime increases significantly the Composite Suitability Index (CSI) in the study reach. Then, using the Building Block Approach (BBA), the scenarios for the modifying dam operations are presented in the study reach. Both Scenario 1 and scenario 2 are proposed by using the hydrological method considering both magnitude and duration of the inflow and averaging the inflow over each month, respectively. It is revealed that the natural flow regime embodied in scenario 1 and scenario 2 increases the Weighted Usable Area (WUA) significantly, compared to the hydropeaking flows. In conclusion, the modifying the dam operations by restoring to the natural flow pattern is advantageous to fish community.

• The Journal of Engineering Geology
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• v.27 no.4
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• pp.429-438
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• 2017

Monte Carlo N-Particle (MCNP) modeling algorithm based on the Monte Carlo method was used to perform the simulation of neutron logging in order to increase the reliability and utilization of neutron logs applied in geological and resource engineering fields. To perform the simulation using MCNP, we used a realistic three-dimensional configuration of neutron sonde and formation. Validation of the modeling was confirmed by comparing the calibration curves of sonde manufacture with those calculated by MCNP modeling. After the validation, lithology effects, pore fluid effects, borehole diameter change, casing effect, and effects of borehole water level were investigated through modeling experiments. Numerical tests indicate that changes in neutron count ratio according to the lithology were quantitatively understood. In case of a borehole with a diameter of 3 inches, ratio of counting rates was higher than expected to be interpreted as borehole fluid has small effects on neutron logging. Effect of casing was also small in general, particular when porosity increases. Since modeling results above the groundwater level showed a tendency opposite to those below the groundwater level, neutron logs can be used to detect groundwater level. The modeling results simulated in this study for various borehole environments are expected to be used for data processing and interpretation of neutron log.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.3
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• pp.31-40
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• 2017

This paper deals with the high precision of GPS measurement reduction and its implementation on near real-time and kinematic mode for those applications requiring centimeter-level precision of the estimated coordinates, even if target stations are a few hundred kilometers away from their references. We designed the system architecture, data streaming and processing scheme. Intensive investigation was performed to determine the characteristics of the GPS medium-range functional model, IGS infrastructure and some exemplary systems. The designed system consisted of streaming and processing units; the former automatically collects GPS data through Ntrip and IGS ultra-rapid products by FTP connection, whereas the latter handles the reduction of GPS observables on static and kinematic mode to a time series of the target stations' 3D coordinates. The data streaming unit was realized by a DOS batch file, perl script and BKG's BNC program, whereas the processing unit was implemented by definition of a process control file of BPE. To assess the functionality and precision of the positional solutions, an experiment was carried out against a network comprising seven GPS stations with baselines ranging from a few hundred up to a thousand kilometers. The results confirmed that the function of the whole system properly operated as designed, with a precision better than ${\pm}1cm$ in each of the positional component with 95% confidence level.

• Journal of The Korean Association For Science Education
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• v.30 no.1
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• pp.140-156
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• 2010

This study aimed to investigate how science teachers perceived major features of the 2007 revised science curriculum and implementing them in classes. The 2007 revised science curriculum included critical features such as creativity, open inquiry, science writing, discussion and STS. In terms of necessity, clarity and complexity of those features for curriculum implementation, teacher perceptions were examined. Particularly with regard to open inquiry assigned 6 class periods per semester as one of the critical features of 2007 revised science curriculum, we asked teachers how they would prepare and implement the technique in their teaching. In results of this study, science teachers agreed on the necessity and importance of those major features of the 2007 revised science curriculum, including creativity, open inquiry, science writing, discussion, and STS. However, they were not clear on how those would work in their classrooms and expected various impediments. Open inquiry was specifically perceived as most negative in its implementation with the mention of various complex reasons. Based on findings in this study, we proposed the 'Dual Action Research Model' for curriculum implementation. It tries to explain how curriculum is implemented in classrooms and diminish the gaps between curriculum developers and teacher users by means of leading teachers to understand the curriculum meaningfully and implement their teaching based on this understanding.

• Journal of Korean Elementary Science Education
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• v.41 no.4
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• pp.658-672
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• 2022

The unique teaching and learning difficulties of speed-related units in elementary school science are mainly due to the student's lack of mathematical thinking ability and procedural knowledge on speed measurement, and curriculums and textbooks must be constructed with these in mind. To identify the implications of composing a new science curriculum and relevant textbooks, this study reviewed the structure and contents of the speed-related units of three curriculums from the 2007 revised curriculum to the 2015 revised curriculum and the resulting textbooks and examined their relevance in light of the literature. Results showed that the current content carries the risk of making students calculate only the speed of an object through a mechanical algorithm by memorization rather than grasp the multifaceted relation between traveled distance, duration time, and speed. Findings also highlighted the need to reorganize the curriculum and textbooks to offer students the opportunity to learn the meaning of speed step-by-step by visualizing materials such as double number lines and dealing with simple numbers that are easy to calculate and understand intuitively. In addition, this paper discussed the urgency of improving inquiry performance such as process skills by observing and measuring an actual object's movement, displaying it as a graph, and interpreting it rather than conducting data interpretation through investigation. Lastly, although the current curriculum and textbooks emphasize the connection with daily life in their application aspects, they also deal with dynamics-related content somewhat differently from kinematics, which is the main learning content of the unit. Hence, it is necessary to reorganize the contents focusing on cases related to speed so that students can grasp the concept of speed and use it in their everyday lives. With regard to the new curriculum and textbooks, this study proposes that students be provided the opportunity to systematically and deeply study core topics rather than exclude content that is difficult to learn and challenging to teach so that students realize the value of science and enjoy learning it.