• Title/Summary/Keyword: 이원진

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A Case of Primary Mucinous Cystadenocarcinoma (원발성 후복막 점액낭샘암종 1예)

  • Ji, Jun-Ho;Lee, Hwa-Jung;Park, Seung-Chan;Park, Jung-Chul;Choi, Eun-Jung;Seo, Hye-Jin;Lee, Won-Sik;Lee, Jung-Lim;Bae, Byung-Jo;Shon, Kyung-Rak;Lee, Kyung-Hee
    • Journal of Yeungnam Medical Science
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    • v.25 no.2
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    • pp.134-138
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    • 2008
  • Primary retroperitoneal mucinous cystadenocarcinoma is a very rare malignancy, and little is known concerning its pathogenesis, optimal treatment, and prognosis. A 29-year-old pregnant woman (21 weeks) presented with abdominal discomfort. CA 19-9, CA 125, and CEA were normal. Abdominal CT scanning revealed a $19{\times}15{\times}13cm$ retroperitoneal tumor. Exploratory laparotomy and tumor excision were performed. Mucinous retroperitoneal implants were removed as completely as possible. Histologically, the tumor showed focal areas of capsular invasion, but free resection margins. The uterus and both ovaries were normal in appearance. No adjuvant therapy was pursued. Six months later, peritoneal and bilateral ovarian metastases were discovered. Hence, we report the details of this case of primary retroperitoneal mucinous cystadenocarcinoma and present a review of the literature.

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Trends Analysis of Suicidal Poisoning in Korea- Comparison before and after the IMF Crisis and the Economic Recession (IMF와 경기침체 전후 음독자살 환자에 대한 분석 -1997년부터 2004년까지 일개 대학병원 응급센터 연구조사를 중심으로-)

  • Lee Won Jae;Park Kyu Nam;Choi Seung Pil;Lee Mi Jin
    • Journal of The Korean Society of Clinical Toxicology
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    • v.3 no.1
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    • pp.33-39
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    • 2005
  • Purpose: Nowadays the Korean society is in the center of time of the social change. Because of dissociation of traditional family, IMF (International Monetary Fund) crisis and economic recession, the mortality rate of suicidal attempts are increasing annually. The majority of suicidal attempts were by poisoning considering the characteristics of korean society. Therefore we studied to find out the characteristics of suicidal poisoning before and after social economic stress, and to suggest the direction for the proper management. Methods: We reviewed medical records of 547 patients of suicide by poisoning who visited the emergency medical centers of St. Mary's hospitals from 1997 to 2004. For the annual trends analysis, we analyzed the demographic and toxicologic data of these patients compared with before and after IMF crisis (1998) and the economic recession ($2003\~2004$). Results: At the time of IMF and the economic recession, the number of suicidal poisoning increased, especially in fifth decade. The refusal rate of toxicological emergency treatment increased. Also the mortality rate and the admission rate to ICU (Intensive Care Unit) increased during the same period. In the result of the comparison analysis, clinical severity and mortality of social problem group were higher. However they couldn't be treated appropriately because of financial problem and the family indifference. Conclusion: At the economic recession period, the severity of suicidal poisoned patients was high. But the refusal rate of toxicologic treatment also increased, so the patients had lost the chance for proper toxicologic treatment. Therefore they would be supported by medical institution and public health.

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Effect of Supplemental Microbial Phytase and Nonphytate Phosphorus Levels on Performance, Digestibility and Egg Quaility in Layer (Microbial Phytase와 무기태 인 수준별 급여가 산란 생산성, 소화율 및 계란 품질에 미치는 영향)

  • 김상호;유동조;박수영;이상진;박용윤;이원준
    • Korean Journal of Poultry Science
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    • v.27 no.3
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    • pp.243-254
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    • 2000
  • The effect of supplemental microbial phytase and non - phytate phosphorus(NPP) levels on layer productivity and nutrient digestibility were conducted in 640 21 weeks - old HyLine brown layer for 12 weeks. Supplemented phytase levels were 0, 300, 500 and 1,000 DPU/kg diet. NPP levels were adjusted with tricalcium phosphate(TCP), which were 0(0.11% NPP), 0.5(0.20), 1.0(0.29) and 1.5%(0.38). ME, CP and Ca levels were maintained at 2,800㎉/kg diet, 16% and 3.5%, respectively. Egg production was increased with phytase compared to without phytase(P〈0.05). Increasement of egg production was higher latter of experimental period. Egg production was not different to phytase levels. Egg production in TCP levels were increased in above 0.5% compared to 0% TCP. Difference of egg production by TCP was higher after 6 week. Especially, egg production to supplemental phytase was higher in 0% TCP. Egg weight was not different to phytase and TCP levels. Egg mass was increased with phytase compared to without phytase, but not difference significantly. There was similar to phytase levels. Egg mass in TCP group was increased in TCP supplementation(P〈0.05). Feed intake was not different in phytase levels, and greater with increasing TCP levels(P〈0.05). Feed conversion was improved with phytase(P〈0.05), and not difference in TCP levels. All of nutrients digestibility tended to improve with phytase, P(P〈0.05), especially. There were not different among phytase levels. The effect of adding phytase was higher in low phosphorus diets compared normal levels. Eggshell breaking strength and eggshell thickness also improved in added phytase(P〈0.05). Tibial ash and P content were slightly increased with phytase, and Ca content also was higher(P〈0.05) compared without phytase. We concluded that supplemental phytase in low phosphorus diet was showed to increase laying performance, feed efficiency, nutrients digestibility, egg quality, and bone development. Phytase supplementation was able to compensate for low NPP diet. We also thought optimum phytase level is 300 DPU, and can decrease NPP supplementation adding phytase in later diet.

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Aviation Security Equipments Certification System in Korea: Suggestions for Improvement (항공보안장비 성능인증제의 고도화 방안에 관한 연구)

  • Lee, Wonjoo;Yu, Sangwoo;Park, Soohong;Kim, Kyunghoon;Ha, Dasom;Seoll, Eunsuk;Han, Soojin;Park, Seoha;Lee, Jisu;Kim, Chanhwi;Kang, Jingu;Lee, Kiyoung
    • Journal of Korean Society for Quality Management
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    • v.48 no.3
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    • pp.395-408
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    • 2020
  • Purpose: This study was performed for advancement of aviation security equipments certification system. Methods: We investigated aviation security equipments certification-related registrations and the latest research trends of explosive detection technologies. Based on the literature studies, we draw the critical issues of the aviation security equipment certification system and suggested improvement direction. Results: We found some inaccuracies of the definition of explosive trace detection equipments, accreditation review committee, and performance evaluation test method. These problems should be modified to suit being practical. Conclusion: The present results would be useful for basic data for modifying aviation security equipments certification systems.

A Case of Internal Myiasis of the Repiratory System Associated with Pneumonia (폐렴과 병발된 호흡기계의 내부 승저증(internal myiasis) 1례)

  • Choi, Eu-Gene;Lim, Dong-Mee;Na, Moon-Jun;Yang, Jong-Myeung;Lee, Young-Ha;Lee, Won-Young
    • Tuberculosis and Respiratory Diseases
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    • v.53 no.6
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    • pp.650-655
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    • 2002
  • Internal myiasis is a rare disease, which has not been reported in Korea, yet. This case report describes a patient with pneumonia associated with internal myiasis. She was 84-year old female who was admitted to the emergency department, Konyang University Hospital as a result of dyspnea and fever and a drowsy mental state. Approximately twenty fly maggots continuously crawled out from the nose at the third hospital day in the intensive care unit. These maggots were almost 7.2mm long and were identified as the genus lucilia belonging to the family Calliphoridae. In addition, a bronchial washing study showed eggs of the dipterous larvae. A lesion of this myiasis case might have been located in the respiratory system of patient. This case is the first internal myiasis of the respiratory system reported in Korea. This cases is discussed with a review of the relevant literature.

Internet Users' Intention to Participate in Preventive Program of Depression (일부 인터넷 이용자의 우울수준에 따른 우울증 예방프로그램 참여의도에 영향을 미치는 요인)

  • Jo, S.J.;Yim, H.W.;Park, Y.M.;Lee, W.C.;Kim, Y.B.
    • Korean Journal of Health Education and Promotion
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    • v.24 no.1
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    • pp.1-16
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    • 2007
  • Objctives: This study purposed to examine the intention to participate in the preventive program of depression of Internet user and to offer the baseline data for development of mental health promotion program. Methods: The internet survey was performed using a self-reported questionnaire on intention to participate in the preventive program of depression, depressive symptom(with Zung's SDS) and so forth from 1,000 internet user (aged $13{\sim}49$ years) via two web sites at Feb($1st{\sim}10th$), 2006. We analyzed the intention to participate in preventive program of depression and the factors related with that intention by depressive level. Results: In the normal group, the intention to participate in a preventive program of depression was influenced significantly by counselling experience(s) on depression(p<.001), and perceived control(p<.001) over the barriers to participation in the preventive program of depression, and marginally by gender. In the depressive group, the smoking habit revealed marginal effect(p=.051) and perceived control over the barriers to participation in the preventive program of depression influenced on that intention significantly(p<.001). Conclusion: Among internet users, especially the solutions of barriers to participate in the preventive program of depression is more important at the intervention program for prevention of depression. In the normal group, we need to consider the use of messages tailored by counselling experience(s) on depression. Some intervention program dealing with two subjects, smoking cessation and prevention of depression concurrently, will be appropriate for the depressive group.

Antioxidant Activity of Pepsin Hydrolysate Derived from Edible Hippocampus abdominalis in vitro and in Zebrafish Models (빅벨리 해마(Hippocampus abdominalis) 유래 펩신 가수분해물의 In vitro와 In vivo에서의 항산화 효능)

  • Kim, Hyun-Soo;Shin, Byeung-Ok;Kim, Seo-Young;Wang, Lei;Lee, WonWoo;Kim, Yoon Taek;Rho, Sum;Cho, Moonjae;Jeon, You-Jin
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.49 no.4
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    • pp.445-453
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    • 2016
  • Seahorse Hippocampus abdominalis a marine teleost fish, has long been used as one of the essential materials in traditional Chinese medicine. However, the uses of seahorse have been limited due to its high cost, despite its beneficial biological activities. Seahorse has not been widely explored for its biofunctional properties and active components. In the present study, the enzymatic hydrolysates of seahorse were prepared by using two digestive enzymes (trypsin and pepsin) and five food grade enzymes (neutrase, protamex, alcalase, kojizyme, and flavourzyme). The enzymatic hydrolysates indicated higher hydrolysis yields than its water extract. Among them, the distilled water-pepsin hydrolysate (DP) which was obtained by distilled water extraction followed by pepsin hydrolysis, showed the highest yield and protein content as well as the highest alkyl radical scavenging activity. Also, it provided protective effects against oxidative stress induced by AAPH in vero cell and zebrafish. Further fractionation based on the molecular weight was carried out to identify it’s active components, and < 5 kDa (less than 5 kDa) molecular weight fraction was confirmed to have the highest antioxidant activity. In conclusion, this study suggests that DP of seahorse has antioxidant properties, and might be a novel and useful material from the marine origin for healthy functional foods and cosmetics.

Budd-Chiari Syndrome Due to Antithrombin, Protein C and Protein S Dficiency and the Complete Obstruction of SVC (항트롬빈, C 단백, S 단백 결핍에 의한 Budd-chiari syndrome과 상대정맥 폐색)

  • 김태윤;이원용;홍기우;김응중;신윤철;김건일;임종윤;유규형;최영진
    • Journal of Chest Surgery
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    • v.35 no.3
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    • pp.239-243
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    • 2002
  • In this case, a 39 year-old man was admitted with Budd-Chiari syndrome associated with complete superior vena cava(SVC) obstruction causing general edema and hepatic failure. Conservative medical therapy was failed. And after the radiologist failed to invasive procedure of balloon dilatation, we attempted the inferior vena cava to right atrium bypass graft. Operation was done through median sternotomy and extended vertical oblique abdominal incision. A 24 mm Dacron tube was placed from the inferior vena cava just below the left renal vein to the right atrium without using the cardiopulmonary bypass pump. The patient's postoperative course was uneventful without signs of bleeding or any other complications. We used anticoagulants at the postoperative first day. At the postoperative 26th day, we performed abdominal Doppler sonography and we confirmed that the graft patency was good. The patient was discharged with SVC obstructive symptoms but we noticed relief of SVC obstructive symptoms in the course of follow-up.

Brain Abscess Uptake at TI-201 Brain SPECT (탈륨-201 SPECT에서 뇌농양 집적)

  • Lee, Won-Hyoung;Han, Eun-Ji;Yoo, le-Ryung;Chung, Yong-An;Sohn, Hyung-Sun;Kim, Sung-Hoon;Chung, Soo-Kyo;Choi, Yeong-Jin
    • Nuclear Medicine and Molecular Imaging
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    • v.41 no.4
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    • pp.339-341
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    • 2007
  • A 22-year-old woman with a history of acute lymphoblastic leukemia was hospitalized for headache and vomiting. CT scan showed a well-defined, ring like enhancing mass in the left frontal lobe with surrounding edema and midline shift. Magnetic resonance imaging demonstrated a round homogeneous mass with a ring of enhancement in the left frontal lobe. Tl-201 brain SPECT showed increased focal uptake coinciding with the CT and MRI abnormality. Aspiration of the lesion performed through a burr hole yielded many neutrophils, a few lymphocytes and histiocytes with some strands of filamentous microorganism-like material. Modified AFB stained negative for norcardia. Gram stain showed a few white blood cells and no microorganism. Antibiotics were started and produced a good clinical response. After one month, CT scan showed markedly reduction in size and extent was observed.

Development of a method for the determination of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in dust using liquld chromatography tandem mass spectrometry (LC-MS/MS를 이용하여 먼지 속의 NNK (4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone) 정량 분석법 개발)

  • Lee, W.K.;Kang, S.J.;Oh, J.E.;Hwang, S.H.;Lee, D.H.
    • Analytical Science and Technology
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    • v.28 no.1
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    • pp.1-7
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    • 2015
  • 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), a tobacco specific nitrosamine found only in tobacco products. The ability to monitor biomarker concentrations is very important in understanding environmental tobacco smoke (ETS). In this study, an efficient and sensitive method for the analysis of NNK in dust was developed and validated using liquid chromatography tandem mass spectrometry. Dust was collected with filter paper soaked in methanol. The standard solution and dust sample were diluted with 100 mM ammonium acetate and extracted using dichloromethane. Our calibration curves ranged from 25 to $10^4pg/mL$. Excellent linearity was obtained with correlation coefficient values between 0.9996 and 1.0000. The limit of detection (LOD) was 5 pg/mL ($S/N{\geq}3$) and the retention time was 10 min. The limit of quantification (LOQ) was 25 pg/mL, and the acceptance criteria was the rate of 98-103% (80-120% at levels up to $3{\times}LOQ$). The coefficient of variations (CV) was 2.8%. Accuracies determined from dust samples spiked with four different levels of NNK racurves ranged that from 25 to 104 pg/mL. Excellent linearity was obtained between 92.1% and 114%. The precision of the method was acceptable (5% of CV). The recovery rates of the whole analytical procedure at low, medium, and high levels were 105.7-116.5% for NNK. The carry-over effects during LC-MS/MS analysis were not observed for NNK. This manuscript summarizes the scientific evidence on the use of markers to measure ETS.