• Proceeding of EDISON Challenge
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• 2017.03a
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• pp.712-714
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• 2017

미병의 예방과 관리의 중요성이 거론되고 있으나, 미병에 대한 분류나 진단을 위한 확고한 근거가 미약한 상황으로서 미병 진단 인자 분류를 위한 생리시스템 모델 개발이 필요한 시점이다. 본 연구의 목적은 개발한 생리학적 모델이 미병 단계를 구별하는데 효과 및 유용성이 있는지를 임상 검증하기 위하여 생리학적 모델 인공지능 시뮬레이션을 개발하고자 함이다. 인공지능 계산은 3층으로 구성된 네트워크를 이용하였으며 각 층은 30개의 neuron들로 구성하였다. 인공지능망의 입력 값은 나이, 수축기 혈압, 이완기 혈압, 심박수 값 (입력 값 4개)이고 출력 값은 혈관 저항값인 Ra이다. 머신러닝 차수를 높이면서 인공지능을 사용하지 않은 생리적 모델로부터 도출된 결과와 인공지능을 통하여 계산된 결과를 비교하였다. 개발된 인공지능계산을 이용한 생리시스템 모델은 대량의 표본집단에서 임상 검증에 기여할 것이다.

• Journal of the Korean Society of Food Science and Nutrition
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• v.33 no.2
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• pp.349-355
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• 2004

The purpose of this study was to estimate effect of academic examination stress on taste perception and nutrient intakes in university students. Physical status, blood pressure, stress score using stress test of 2 types, recognition threshold and preference for taste, nutrient intakes using diet record method were measured before and after examination in 20 subjects. Mean age, height, weight, and BMI of the subjects were 23.39$\pm$1.20 years, 164.56$\pm$7.99 cm, 60.66$\pm$13.23 kg, 22.28$\pm$4.56 kg/$m^2$, respectively. Stress scores before examination of the subjects were significantly higher than those after examination. There were no significant differences in blood pressure, pulse rate, recognition threshold and just right concentration for sweetness and saltness, and food and nutrient intakes between pre- and post-examination. There were significantly positive correlation between stress score and diastolic blood pressure. And threshold concentration for saltness was positively correlated with threshold concentration for sweetness and animal protein intake. These results show no effect of examination stress on taste perception and nutrient intakes in university students. This may be due to low level of stress. Therefore, it is needed to study about effect of more higher level of stress on taste perception and nutrient intakes.

• The Korean Journal of Applied Statistics
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• v.21 no.6
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• pp.1027-1035
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• 2008

This research is aimed to investigate the effect of repetitive dive on physiological reactions, change of stress hormones in no decompression limit of sport SCUBA dive, an emerging recreational activity recently. In order to compare physiological reactions prior to and after the initial dive and after repetitive dive at a certain depth of a place, eight adult male divers with more than forty dives, who reside in Busan and were certified, were selected. The research results obtained from the procedures described above are follows: First, for physiological reactions, heart rates, temperatures, and systolic blood pressures had significant difference among prior to and after the initial dive and after the repetitive dive, while diastolic blood pressures did not show remarkable difference as it increased before and after the first dive but decreased following the repetitive dive again. Second, for change of stress hormones, it was not significantly different prior to and after the initial dive and following the repetitive dive, as well as before and during the first dive and the repetitive dive.

• Journal of Korean Physical Therapy Science
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• v.3 no.2
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• pp.989-995
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• 1996

This study was conducted to investigate variation of cardiopulmonary function by use of building stairs, a questionnair survey and measurement was carried out for 50 students of department of physical therapy Andong Junior College from 20th September to 3rd October, 1995. The result were as follows: The average systolic blood pressure(SBP) of stability for 50 college students who were measured was 121.3 mmHg, the average diastolic blood pressure(DBP) of stability was 78.5 mmHg, the average pulse frequency of stability was 71.8(frequency/min), the average breathing frequency of stability was 20.4(frequency/min), and the body temperature of stability was $36.8^{\circ}C$. SBP among the second, third, and fourth floors was 129.0 mmHg, 127.0 mmHg, and, 132.0 mmHg (p=0.1919), DBP was 80.1 mmHg, 76.5 mmHg, and, 82.0 mmHg (p=0.4229), the pulse frequency was 74.0, 73.1, and 74.0(frequency/min). The breathing frequency among the second, third, and fourth floors was statistically gradually increased according to 21.4, 23.1 and 24.6(frequency/min)(p=0.0071). The body temperature among the second, third, and fourth floors was statistically less and less decreased according to $36.8^{\circ}C,\;36.6^{\circ}C$ and $36.5^{\circ}C$(p=0.0040). It was revealed by this study, the breathing frequency among the second, third, and fourth floors was statistically significant increased, the body temperature was statistically significant decreased.

• The Korean Journal of Physiology
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• v.21 no.2
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• pp.201-210
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• 1987

수온변화에 따른 심맥관계 및 신장기능의 변화와 생체실험을 통한 온도에 의한 adrenoceptor의 변형을 알아보기 위해, 무마취 자라에서 $18^{\circ}C$에서 $25^{\circ}C$로 수온을 증가시 나타나는 혈압, 심박동수 및 신장기능의 변화를 관찰하고, epinephrine 1 ug/kg과 10 ug/kg을 상이한 온도에 노출된 자라의 정맥내 투여하여 나타나는 효과를 비교하였다. 1) $18^{\circ}C$에서 $25^{\circ}C$로 수온을 증가시킴에 따라 심박동수는 현저히 증가하여 일정하게 유지되었으나, 혈압 및 혈장 renin 활성도는 변화하지 않았다. 온도증가에 의해 뇨량, 사구체여과율 및 전해질 배설량의 현저한 증가를 보였으나 90분부터는 서서히 감소하기 시작하였다. 2) 수온 $18^{\circ}C$에 노출된 자라에서 epinephrine은 dose-dependent한 양상으로 혈압 및 심박동수를 증가시켰으며, 다량의 epinephrine 투여시 작용시간은 현저히 연장되어 있었다. $25^{\circ}C$에 노출된 자라에서는 epinephrine에 의한 혈압상승 효과 및 심박동수 증가는 나타났으나, dose dependency나 작용시간의 차이는 발견할 수 없었다. 3) 동량의 epinephrine에 의한 혈압 및 심박동수의 증가효과는 $18^{\circ}C$와 $25^{\circ}C$에 노출된 자라에서 유의한 차이를 발견할 수 없었으나, $18^{\circ}C$에 노출된 자라에서 epinephrine의 작용시간 및 반감기가 현저히 연장되어 있었다. 4) Epinephrine 투여에 의해 뇨량, 사구체여과율 및 전해질 배설량의 증가를 관찰하였으며, 이는 dose-dependent 양상이었다. 그러나, 신장효과의 유의한 차이는 상이한 온도에 노출된 두 군에서 발견할 수 없었다. 이상의 결과로, 온도증가에 의한 이뇨 및 sodium 배설효과는 혈관이완에 의한 사구체여과율의 증가에 기인한 것으로 사료되며, 상이한 온도에 노출된 자라에서 epinephrine 효과의 차이를 발견할 수 없었던 것은 본 실험에서 가한 좁은 범위의 온도의 변화 내에서는 adrenoceptor의 변형이 나타나지 않을 것이라고 추론하였다. 그러나 저온에서의 epinephrine의 작용시간의 연장은 아마도 epinephrine의 파괴 효소의 활성도의 감소인 것으로 사료된다.

• Journal of the Korea Convergence Society
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• v.11 no.7
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• pp.35-40
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• 2020

Recently, devices such as smart watches capable of measuring small biosignals have been released. Body composition, blood pressure, heart rate, and oxygen saturation can be easily obtained. However, the part that is not trusted by the user is accuracy. These biosignals are sensitive to the external environment and have large fluctuations depending on the conditions inside the subject's body. Blood pressure measurements, in particular, still give different results, depending on how the conditions in the body are handled. Therefore, in this study, PPG was analyzed to measure PTT at two points of 80% and 100%, the highest in PTT measurement. The effect of the measured value on SBP and DBP was analyzed and a method was proposed to increase the accuracy. As a result of the study, the measured value of PTT at 80% of the peak PPG is more effective in estimating blood pressure of SBP and DBP than the value measured at 100%. In the regression analysis of the rate of change blood pressure estimation, the coefficient of determination of SBP (80%) was 0.6946, and DBP (100%) was 0.547.

• The Korean Journal of Food And Nutrition
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• v.15 no.2
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• pp.165-172
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• 2002

Studies were carried out to observe the influence of the Aralia continentalis Kitagawa root on blood pressure and blood constituents of the 24 hypertensive elderly(10 men and 14 women aged over 60). Total subjects were divided into three groups according to taking antihypertensive medications(A), antihypertensive medications and mixing beverages with the Aralia continentalis Kitagawa root(B) or mixing beverages with Aralia continentalis Kitagawa root(C). The systolic blood pressure of C group was significantly lower than that of A and B groups. The diastolic blood pressure of C group was lower than A and B groups. The blood glucose level of C group was a little lower than that of A and B groups. The level of TG increased more in A group than C group and decreased in B group. The levels of T-cholesterol and LDL-cholesterol lowered in B and C groups and HDL-cholesterol level was higher in C group. The GOT, GPT and T-bilirubin levels of C group were significantly higher than others. Mixing beverages with Aralia continentalis Kitagawa root did not affect on blood protein and non-protein nitrogens. In conclusion, mixing beverages with Aralia continentalis Kitagawa root had an effect on lowering blood pressure, blood glucose, T-cholesterol and LDL-cholesterol concentrations.

• Journal of the Korean Society of Food Science and Nutrition
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• v.32 no.3
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• pp.464-468
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• 2003

The antihypertensive and cholesterol- lowering effects of Monascus koji (M. koji) prepared with Monascus ruber IFO32318 were examined in spontaneously hypertensive rats (SHR). Control was fed a normal diet and groups I, II or III were fed diets containing 0.03%, 0.1% or 0.3% M. koji for 8 weeks, respectively. After 8 weeks, all animals were fed normal diets in the following 2 weeks. The blood pressure of rats fed M. koji added diets were significantly attenuated as compared with control and the diet containing high concentration of M. koji had a tendency of stronger antihypertensive effect. These differences lasted throughout the experimental period when they were fed experimental diet. For 2 weeks after the 8 weeks of experimental diet all groups were fed the same normal diet and the differences of blood pressure caused by M. koji disappeared. In rats fed the M. koji added diet, the serum total cholesterol (TC), HDL cholesterol (HDL-C), LDL cholesterol (LDL-C) were not differed compared with control, but VLDL cholesterol (VLDL-C) was significantly lowered. M koji also significantly decreased serum risk factors, both TC/HDL-C ratio and non HDL-C/HDL-C ratio. Consequently, it is suggested that M. koji may play an important role to attenuate hypertension and to improve serum lipid Profiles.

• Journal of radiological science and technology
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• v.31 no.1
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• pp.33-39
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• 2008

Abdominal obesity, especially, visceral obesity is thought to be a risk factor of type 2 diabetes and cardiovascular disease such as hypertension, hyperlipidemia, coronary artery disease. Based on previous studies visceral fat accumulation is highly related to these diseases compared to subcutaneous fat accumulation. The purpose of this study was to see the relation between abdominal obesity and lipid profiles in adult women. The included subjects were 25 adult women(BMI > $23\;kg/m^2$), who visited the obesity clinic in a general hospital from April 2006 to September 2007. Blood pressure, fasting glucose and lipid profiles were measured. The abdominal fat distribution had been assessed by CT scan at the level of L4-L5. From bivariate analyses, the visceral fat accumulation showed negative correlations with TC and TC/HDL. The BMI, total abdominal fat and Visceral fat/Subcutaneous fat ratio showed significant correlations with visceral fat accumulation. From linear regression analyses of all the study subjects, TC, TG and HDL were found to be determinants of the visceral fat accumulation($R^2\;=\;0.474$).

• Journal of the Institute of Electronics Engineers of Korea SP
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• v.48 no.2
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• pp.102-108
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• 2011

The existing vessels lighting control system has several problems, which are complexity of construction and high cost of establishment and maintenance. In this paper, We designed low cost and high performance lighting control system at digital vessel environment. We proposed a system which recognize the user's emotions after obtaining the biological informations about user's bio information(pulse sensor, blood pressure sensor, blood sugar sensor etc) through wireless sensors controls the LED Lights. This system classified emotions using backpropagation algorithm. We chose 3,000 data sets to train the backpropagation algorithm. As a result, obtained about 88.7% accuracy. And the classified emotions find the most appropriate point in the method of controlling the waves or frequencies to the red, green, blue LED Lamp comparing with the 20-color-emotion models in the HP's 'The meaning of color' and control the brightness or contrast of the LED Lamp. In this method, the system saved about 20% of the electricity consumed.