• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.4 no.1
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• pp.68-78
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• 1993

The pathophysiology and neural mechanism involved in Tourette's and chronic motor tic disorder are highly controversial. In order to investigate the functional abnormalities of brain. In Tourette's and chronic motor tic disorder, 42 children with Tourette's and chronic motor disorder underwent single photon emission computed tomography(SPECT) using Tc-99m-HM-PAO. The results are summarized as follows : 1) 31.0% (13/42) of this series revealed perfusion defect in cerebral cortex. 2) 4.8% (2/42) revealed perfusion defect in basal ganglia. 3) 4.8(2/42) revealed perfusion defect in thalamus. 4) 16.7%(7/42) showed perfusion defect in cerebellum. 5) The frequency of abnormal perfusion showed no significant difference between tic with and without attention deficit hyperactivity disorder. 6) The frequency of abnormal perfusion showed no significant difference between Tourette's and chronic motor tic disorder. These findings support the hypothesis of a possible involvement of brain dysfunction in the production of Tourette's and chronic motor tic disorder, and quantification of blood flow and co-registration with magnetic resonance imaging will increase the validity of this study.

• Geophysics and Geophysical Exploration
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• v.2 no.2
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• pp.104-111
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• 1999

As a practical developing step of electromagnetic (EM) tomography technique, we quantitatively analyzed the effects of borehole fluid and casing on the borehole EM responses. The EM response turns out to have nothing to do with the property of the borehole fluid except in the close vicinity of the transmitter, which shows the wide perspective of the application of borehole EM. Single-hole responses in the presence of the steel casing throughly reflect those of the casing itself since its extremely high induction number or shallow skin depth. EM responses through steel casing do show the information of the host medium. In the near field region which corresponds to low frequency or the vicinity of the borehole, however, we can not separate the signal containing the information of the host from that of casing. Otherwise, the severe attenuation of energy in the casing at high frequencies renders the signal undetectable. The optimum frequency is, therefore, to be chosen to extract the information of the host considering both the property of the casing and the skin depth of the medium and the practical technique to determine the casing property through single-hole measurements is required.

• Journal of Gastric Cancer
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• v.6 no.3
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• pp.189-192
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• 2006

Acute disseminated intravascular coagulation (DIC) associated with gastric cancer is not common and has short survival of 1 to 3 weeks. Systemic chemotherapy in spite of hematologic unstability for gastric cancer may prolong survival time. A 47-year-old woman who complained of dyspnea, vaginal bleeding and easy bruisibility was diagnosed to stage IV gastric cancer with acute disseminated intravascular coagulation based on the laboratory data. She also had multiple bone metastases and bone marrow involvement. This is the first case treated with combination chemotherapy of irinotecan and cisplatin for advanced gastric cancer complicated by disseminated intravascular coagulation at the time of diagnosis, With systemic chemotherapy, some of the bleeding symptoms and the DIC process improved, even not completely recovered. However the patient died of disease progression and survival time was 12 weeks.

• Journal of the Korean Society of Food Science and Nutrition
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• v.36 no.3
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• pp.298-300
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• 2007

This study investigated the hepatoprotective effects of an ethanol extract of Petasites japonicus S. et. Z. Max. (PJ) on alcohol-induced liver-damaged rats. Sprague-Dawley rats weighing $100{\sim}150\;g$ were divided into 5 groups; normal diet group (NOR), alcohol (35%, 10 mL/kg/day) treated group (CON), PJ 200 mg/kg/day treated group (PJ1), PJ 200 mg/kg/day and alcohol treated group (PJ2), and PJ 400 mg/kg/day and alcohol treated group (PJ3). The growth rate of the control group was higher than that of normal group, whereas the group administered PJ concomitantly was significantly increased. Also, feed efficiency ratio decreased by alcohol administration was gradually increased to the adjacent level of the normal group by administering PJ. The AST activity in serum elevated by alcohol was significantly decreased by administering the high dosage of PJ, but exerted no significant change on serum ALT activity. It was also observed that the hepatic activities of catalase and GSH-Px increased by alcohol were markedly decreased in PJ2 and PJ3, but not in the activities of XO and SOD as compared with the control group. The depleted content of GSH by alcohol was increased to the level of normal group by administering PJ in a dose-dependant manner. In conclusion, these results suggest that PJ may have a possible protective effect on liver function in hepatotoxicity-induced rat by alcohol administration.

• Journal of the Korean Institute of Landscape Architecture
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• v.46 no.2
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• pp.1-13
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• 2018

This work discusses the major roles of digital technologies in the history of landscape architectural drawing, and offers a critique of the dominant trend towards realism in recent digital landscape representations. During the period of transition from conventional drawing tools, computer technologies generally functioned as mechanical tools to imitate prior manual techniques. Specifically, the GIS was served as a mechanical tool to efficiently process the manual layer cake; CAD software generally functioned to translate physical models to two-dimensional construction documents while graphic software generally functioned as a tool to perform processes similar to those of manual collage and montage techniques. Recent digital landscape drawings tend to adopt a realistic depiction like the painting of landscape appearance. In the representations, discernible traces of cutting and assembling are removed via graphic software; thus, the complete representations are perceived as if they were a copy of an actual landscape. The realistic images are an easy way to communicate with the public. However, it is difficult to achieve a full embodiment of all of the multisensory characteristics of a landscape through these visuals. They often deceive viewers by visualizing idealized conditions of not-yet-actualized landscapes and production of the final images takes up a large portion of the overall design process. Alternatively, 3D digital modeling of landscape performance and creative uses of digital technologies during the overall design process, as well as hybridized techniques with different drawing techniques and technologies, provide the opportunity to explore various aspects of a landscape.

• Journal of the Korea Convergence Society
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• v.11 no.7
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• pp.97-104
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• 2020

The Purpose of this paper was to explore the effect of hearing impairment on HRQOL in Korean elders. We carry out a cross-sectional analysis using nationally representative data from the KNHANES, 2018. A total of 528 elders who had hearing impairment were included. Statistical analysis was performed using SPSS 25.0, χ²-test, t-test, correlation, and regression analysis to confirm the quality of life, and the influencing factors. There were significant differences in HRQOL according to gender, age, education, marital status, income, occupation, number of household members, tinnitus, number of comorbidities, smoking status, alcohol drinking status, subjective health status, regular exercise, restriction of activity, depressive mood and perceived stress. The results indicated that age, BMI and number of comorbidities had a significant negative association with HRQOL. In addition, marital status, number of comorbidities, body mass index, subjective health status, regular exercise, restriction of activity and perceived stress were predictors of life quality in elders with Hearing Impairment and the variable in the health-related quality of life was explained by 37.3%. In order to improve the HRQOL of elders with hearing impairment, multidisciplinary efforts and development of educational programs are required.

• The Korean Journal of Nuclear Medicine
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• v.31 no.4
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• pp.427-432
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• 1997

Re-188 is useful candidate for therapeutic radionuclide because it has a physical half life of 17 hours, contains beta emissions suitable for therapy(maximum energy 2.12MeV) and emits a gamma ray that is suitable for quantitative diagnostic scanning(155keV). To use Re-188 as a radionuclide compound of angioplasty balloon radiotherapy, we investigated the labelling method and biodistribution of Re-188-DTPA We postulated that labeled Re-188-DTPA is preferable because it would be excreted via urinary system more easily than other compounds. To label Re-188 with DTPA, 1ml of 222MBq(6mCi) of Re-188 was added to DTPA solution(DTPA 20mg, $SnCl_2{\cdot}2H_2O$ 10mg, pH 3.5) and boiled at $100^{\circ}C$ for 120min in water bath. pH was adjusted to 5 with 2.3% sodium acetate. Labeling efficiency was measured using TLC-SG(acetone, saline). We evaluated biodistribution of Re-188-DTPA in sacrificed mice at 10 and 60 minutes after injection. We acquired images of kidneys, and drew time-activity curves in normal dogs and rats and calculated Tmax and Tl/2 in rats. The labelling efficiency was 95.7% on average. Labelling of Re-188-DTPA was.stable(90% after 5hours) in vitro at room temperature. According to time-activity curves of dogs and rats, it took 15 to 20 minutes after injection for Re-188-DTPA to be washed out through kidneys. In conclusion, Re-188-DTPA was successfully labeled, Re-188-DTPA was stable in vitro and was excreted early via kidneys in animals. We could recommend Re-188-DTPA as radionuclide of potential use in angioplasty balloon radiotherapy.

• 한국지구물리탐사학회:학술대회논문집
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• 2006.06a
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• pp.117-122
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• 2006

In the geophysical monitoring to understand the change of subsurface material properties with time, the time-invariant static subsurface model is commonly adopted to reconstruct a time-lapse image. This assumption of static model, however, can be invalid particularly when fluid migrates very quickly in highly permeable medium in the brine injection experiment. In such case, the resultant subsurface images may be severely distorted. In order to alleviate this problem, we develop a new least-squares inversion algorithm under the assumption that the subsurface model will change continuously in time. Instead of sampling a time-space model into numerous space models with a regular time interval, a few reference models in space domain at different times pre-selected are used to describe the subsurface structure continuously changing in time; the material property at a certain space coordinate are assumed to change linearly in time. Consequently, finding a space-time model can be simplified into obtaining several reference space models. In order to stabilize iterative inversion and to calculate meaningful subsurface images varying with time, the regularization along time axis is introduced assuming that the subsurface model will not change significantly during the data acquisition. The performance of the proposed algorithm is demonstrated by the numerical experiments using the synthetic data of crosshole dc resistivity tomography.

• Applied Chemistry for Engineering
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• v.10 no.4
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• pp.523-530
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• 1999

Acrylic pressure-sensitive adhesive has been made utilizing organic solvents, but nowadays it is made by solvent-free system due to environmental problems. In this study, emulsion polymerization were carried out at $40^{\circ}C$ with methacrylic acid(MAA), n-butyl acrylate(n-BA) and 2-ethylhexyl acrylate(2-EHA) as monomers in the presence of anionic(sodium dodecyl sulfate, SDS) and nonionic(ethylene oxide types) surfactant mixtures. The overall conversion of the polymerization reaction in a mixed surfactant system was found to be higher than that in a single surfactant system. Emulsion stability in mixed or anionic surfactant systems was found to be over 12 week, which was better than that in nonionic surfactant system. Emulsion particle size decreased as surfactant content increased. The Tg and molecular weight of emulsion polymer were inependent of the type, the amount and the mixing ratio of surfactant. Based on the results of stability and peel strength, the optimum nonionic surfactant ratio in total 4 g of surfactant mixture systems is found to be 40~60% by weight where the nonionic surfactant has 50 ethylene oxide groups and 16~18 carbon atoms in hydrophobic alkyl chain.

• Radiation Oncology Journal
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• v.6 no.1
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• pp.93-99
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• 1988

Some modern accerelators provide a dual energy for photon beam treatment. The main advantages of dual energy in the treatment of rectosigmoid or rectal cancer are as fellows. 1. Dose in the critical organ such as small intestine, bladder and genital organ are reduced. 2. Presacral and perineal area is fully covered. Dose distribution analysis such as calculation of dose in a target volume, isocenter, $D_{nax}$ and dose spectrum in any region of interest are possible. Examples of plan are given and results are discussed.