• Korean Journal of Acupuncture
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• v.22 no.4
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• pp.1-8
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• 2005

배경 : 체질의학에서 진단의 중요성에도 불구하고 팔체질의학의 맥진의 신뢰성에 대한 과거 연구가 거의 없었다. 목적 : 본 예비연구는 팔체질의학의 맥진에 대한 진단자 간의 신뢰성 및 진단자 내의 신뢰성을 검사하기 위함이다. 재료 및 방법 : 팔체질의학을 이용한 진료 경력이 3년 내지 5년 되는 한의사 두 명이 실험에 참여하였다. 31명의 건강한 대학생들의 팔체질을 맥진을 통해 진단하고 그 결과를 확신도와 함께 각각 기록하도록 하였으며 이 중 5명은 각각 진단자로부터 3회씩 진단을 받도록 하였다. 그 결과를 분석하여 진단자 간의 신뢰성과 진단자 내의 신뢰성을 검사하였다. 아울러 진단에 대한 확신도와 결과와의 상관성이 있는지도 조사하였다. 대상자와 진단자는 서로를 알 수 없도록 가리개를 하고 실험을 진행하였다. 결과 : 진단자 간의 일치도는 35.7%였으며 카파 계수는 0.232로 보통 이하 수준인 것으로 나타났다. 진단자 내 일치도는 진단자 별로 각각 89%, 66.83%로 나타났다. 다만 두 진단자 사이의 결과가 일치하는 경우 불일치하는 경우보다 진단자의 확신도가 높은 것으로 드러났다 결론 : 본 연구에서는 팔체질의학의 맥진의 진단자 간, 진단자 내의 신뢰성이 비교적 낮은 것으로 나타났다. 이는 진단의 변수가 많고 진단자의 숙련도나 대표성의 문제 등 여러 가지 요소들로 인한 결과로 파악된다. 팔체질의학의 진단자 간, 진단자 내의 신뢰성에 대한 향후 연구가 절실히 요구된다.

• Journal of the Korean Society of Radiology
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• v.82 no.4
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• pp.838-850
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• 2021

The incidence and prevalence of nontuberculous mycobacterial pulmonary disease (NTM-PD) is increasing worldwide, including in Korea, and the clinical importance of NTM-PD is also rapidly increasing. The diagnosis and management of NTM-PD is difficult. Radiologic evidence is mandatory to diagnose NTM-PD, and the radiologic findings may be the first evidence of the disease in many patients. Traditionally, NTM-PD demonstrates two different radiologic forms: fibrocavitary and nodular bronchiectatic. However, the disease also shows non-specific and a wide spectrum of radiologic features. Radiologists must be aware of the radiologic features of NTM-PD and should include them in the differential diagnosis. This review focuses on the epidemiology in Korea, diagnostic criteria, and radiological features of NTM-PD for radiologists.

• The Korean Journal of Blood Transfusion
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• v.23 no.2
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• pp.169-172
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• 2012

Lutheran a antigen ($Lu^a$) is detected in 6 to 8% of Caucasians and Africans. In Korean and other Asian populations, it is very rare or nearly absent. Therefore, although $Lu^a$ has a considerable immunizing capacity, sensitization to $Lu^a$ is a rare event. Here we report on a rare case of anti-$Lu^a$ in a 70 year-old female patient with Lu (a-/b+) phenotype and review the relevant literature. Due to the paucity of $Lu^a$ positive panel cells in antibody screening and identification tests, detection of this rare antibody to $Lu^a$ antigen is not feasible. Therefore, we should keep in mind the possibility of the misleading false negative result in detection of antibody to this low incidence antigen.

• Annals of Clinical Microbiology
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• v.19 no.1
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• pp.20-23
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• 2016

In the RNA-based study, it is important to extract high-quality RNA. However, RNA extraction from Mycobacterium tuberculosis is problematic due to its thick, waxy cell wall rich in mycolic acid, which renders the cells resistant to lysis. Using TRIzol reagent and several powerful bead-beating steps, a high quantity of RNA was obtained.

• Laboratory Medicine Online
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• v.7 no.2
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• pp.83-87
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• 2017

Pseudohypoparathyroidism (PHP) is a rare disorder caused by genetic and epigenetic aberrations in the GNAS complex locus resulting in impaired expression of stimulatory G protein ($Gs{\alpha}$). PHP type Ib (PHP-Ib) is characterized by hypocalcemia and hyperphosphatemia due to renal resistance to the parathyroid hormone, and is distinguished from PHP-Ia by the absence of osteodystrophic features. An 11-yr-old boy presented with poor oral intake and cramping lower limb pain after physical activity. Laboratory studies revealed hypocalcemia, hyperphosphatemia, and increased parathyroid hormone levels. The GNAS complex locus was evaluated using the methylation-specific multiplex ligation-dependent probe amplification (MS-MLPA) assay. Gain of methylation in the NESP55 domain and loss of methylation in the antisense (AS) transcript, XL, and A/B domains in the maternal allele were observed. Consequently, we present a case of PHP-Ib diagnosed using MS-MLPA.

• Progress in Medical Physics
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• v.3 no.2
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• pp.33-42
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• 1992

The fundamental principles of MRS, one of the most powerful analytical tools in seience, is introduced as the promising methodology in the diagnostic radiology of medical science. A variety of applications of MRS indicates the possibility of more accurate and sensitive diagnosis in medicine. The combination of anatomical informations by MRI and biochemical informations by MRS provides the bright prospect in the diagnostic radiology.

• Journal of the Korean Society of Radiology
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• v.85 no.1
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• pp.147-160
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• 2024

Purpose To define an MRI scoring system for differentiating xanthogranulomatous cholecystitis (XGC) from wall-thickening type gallbladder cancer (GBC) and compare the diagnostic performance of the scoring system with the visual assessment of radiologists. Materials and Methods We retrospectively analyzed 23 and 35 patients who underwent abdominal MRI and were pathologically diagnosed with XGC and wall-thickening-type GBC after surgery, respectively. Three radiologists reviewed all MRI findings. We defined a scoring system using these MRI findings for differentiating XGC from wall-thickening type GBC and compared the area under the curve (AUC) of the scoring system with the visual assessment of radiologists. Results Nine MRI findings showed significant differences in differentiating the two diseases: diffuse gallbladder wall thickening (p < 0.001), mucosal uniformity (p = 0.002), intramural T2-high signal intensity (p < 0.001), mucosal retraction (p = 0.016), gallbladder stones (p < 0.001), T1-intermediate to high-signal intensity (p = 0.033), diffusion restriction (p = 0.005), enhancement pattern (p < 0.001), and phase of peak enhancement (p = 0.008). The MRI scoring system showed excellent diagnostic performance with an AUC of 0.972, which was significantly higher than the visual assessment of the reviewers. Conclusion The MRI scoring system showed better diagnostic performance than the visual assessment of radiologists to differentiate XGC from wall-thickening-type GBC.

• Laboratory Medicine Online
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• v.1 no.1
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• pp.64-66
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• 2011

Anti-Sd^a is of no clinical significance, because it rarely causes hemolytic transfusion reactions. Even when its presence is suspected during antibody screening test, further identification of the antibody is usually not performed. We experienced a case of anti-Sd^a in 73 yr-old male patient showing mixed field agglutination by microcolumn agglutination. Antibody specificity could not be identified by conventional antibody identification test, and it was proven to be anti-Sd^a by urine neutralization test. In spite of its little clinical significance, it may give incompatible crossmatching results reacting with Sd^a antigen, which occurs at a high frequency in general population. When incompatible crossmatch results arising from anti-Sd^a are suspected, the problem may be solved by using the urine-neutralized serum of in crossmatching test.

• Journal of the Korean Society of Radiology
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• v.81 no.3
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• pp.530-548
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• 2020

Thyroid radiology practice is a medical practice in which thyroid diseases are diagnosed using imaging modality and treated by imaging-based interventional techniques, and the primary care target is thyroid nodular disease. Diagnosis of thyroid nodules is primarily done by ultrasound imaging and biopsy; thyroid nodules can be treated by non-surgical interventional treatment and thyroidectomy. Ethanol ablation is the first-line treatment for cystic benign nodules, and radiofrequency ablation is used for the treatment of benign solid nodules and recurrent thyroid cancers. Thyroid radiology practice has an essential clinical role in diagnosis and nonsurgical treatment of thyroid nodular diseases, and treatment should be performed based on standard care guidelines for proper patient care. In order to provide the best care to patients with thyroid nodular disease, it is desirable to treat patients in the radiology outpatient clinic. Thyroid radiology practice centered on outpatient clinic practice needs to be expanded.

• Annals of Clinical Microbiology
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• v.17 no.1
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• pp.23-27
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• 2014

Rapidly growing mycobacteria are ubiquitous in the environment and are increasingly being recognized as opportunistic pathogens. Recently, a new species, Mycobacteium conceptionense, has been validated from the Mycobacterium fortuitum third biovariant complex by molecular analysis. However, there are few reports, and postsurgical wound infection by this species is rare. We report a case of postsurgical wound infection caused by M. conceptionense in an immunocompetent patient that was identified by a sequencing analysis of 16S rRNA, hps65, and rpoB genes.