• Journal of the Korean Society of Radiology
• /
• v.17 no.3
• /
• pp.441-447
• /
• 2023

Lead(Pb), which is currently mainly used for shielding purposes in the medical radiation, has excellent radiation shielding functions, but is continuously exposed to radiation directly or indirectly due to the harmfulness of lead itself to the human body and the inconvenience caused by its heavy weight. Research on shielding materials that are human-friendly, lightweight, and convenient to use that can block risks and replace lead is continuously being conducted. In this study, based on the commonly used polyethylene terephthalate (PET) film and the fabric material used in actual radiation protective clothing, a multi-layer thin film was realized through sputtering and vacuum deposition of bismuth, tungsten, and tin, which are metal materials that can shield radiation. Thus, a shielding film was produced and its applicability as a radiation shielding material was evaluated. The radiation shielding film was manufactured by establishing the optimized conditions for each shielding material while controlling the applied voltage, roll driving speed, and gas supply amount to manufacture the shielding film. The adhesion between the parent material and the shielding metal thin film was confirmed by Cross-cut 100/100, and the stability of the thin film was confirmed through a hot water test for 1 hour to measure the change of the thin film over time. The shielding performance of the finally realized shielding film was measured by the Korea association for radiation application (KARA), and the test conditions (inverse wide beam, tube voltage 50 kV, half layer 1.828 mmAl) were set to obtain an attenuation ratio of 16.4 (initial value 0.300 mGy/s, measured value 0.018 mGy/s) and damping ratio 4.31 (initial value 0.300 mGy/s, measured value 0.069 mGy/s) were obtained. by securing process efficiency for future commercialization, light and shielding films and fabrics were used to lay the foundation for the application of films to radiation protective clothing or construction materials with shielding functions.

• Journal of the Korean Society of Radiology
• /
• v.15 no.5
• /
• pp.613-620
• /
• 2021

The purpose of this study is to propose a convolutional neural network model that can classify normal and abnormal(cardiomegaly) in chest X-ray images. The training data and test data used in this paper were used by acquiring chest X-ray images of patients diagnosed with normal and abnormal(cardiomegaly). Using the proposed deep learning model, we classified normal and abnormal(cardiomegaly) images and verified the classification performance. When using the proposed model, the classification accuracy of normal and abnormal(cardiomegaly) was 99.88%. Validation of classification performance using normal images as test data showed 95%, 100%, 90%, and 96% in accuracy, precision, recall, and F1 score. Validation of classification performance using abnormal(cardiomegaly) images as test data showed 95%, 92%, 100%, and 96% in accuracy, precision, recall, and F1 score. Our classification results show that the proposed convolutional neural network model shows very good performance in feature extraction and classification of chest X-ray images. The convolutional neural network model proposed in this paper is expected to show useful results for disease classification of chest X-ray images, and further study of CNN models are needed focusing on the features of medical images.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.20 no.6
• /
• pp.587-591
• /
• 2019

Fine dust aerated in the atomsphere penetrates our lungs and blood lines through respiratory. Recent fine dust problems in Korea leads to development of various air purifiers. The researchers used this to study systems that could replace chemical filters. In order to compare the effect of the reduction of moss and conventional chemical filter(Hepa), a 1 cubic meter cube was prepared and the amount of the concentration of fine dust reduction was compared under controlled environment. Under the high concentration of fine dust, a test was done to figure out the reduction rate of the fine dust concentration by using air purification system with moss, hepa, and no filter. The air purification system(moss, hepa, and no filter) were operated 90 times in total, 30 times each. The test explains that the reduction of the fine dust amount and the rate of fine dust concentration. The results illustrate that the reduction of the amount fine dust was 138.93 after using air purification system with moss filter. In contrast, the usage of air purification system with hepa filter reduced the amount of fine dust to 76.57. And the air purification with no filter shows that the slight reduction of fine dust amount at 0.10. In the rate of fine dust concentration, moss filter was significantly higher than that of hepa, no filter (0.2379, 0.1298 and 0.0063 each). The results have confirmed that moss is effective in reducing fine dust concentration, and it is expected that with further improvement it can be used as a means to replace or supplement existing chemical filters in air purifier.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.22 no.6
• /
• pp.413-419
• /
• 2021

The purpose of this study was to investigate the ability to treat and prevent infection by multiple Gram-negative bacterial pathogens as a last choice option in the treatment of serious infections in clinical settings. The global spread of extended-spectrum 𝛽-lactamases (ESBLs) and/or carbapenemases in microorganisms are of enormous concern to health services because they are often associated with multi-drug resistance which significantly restricts the antibiotic treatment options. In this study, the antimicrobial resistance profiles of bacteria isolated from South Korean market-derived meat samples were determined by the disc diffusion method. PCR was used to detect the presence of antibiotic resistance genes and ESBL producing genes. In total, we tested 181 isolated colonies from 36 market-derived meat samples. Single PCR and DNA sequencing results revealed that genes blaVIM, blaBIC, blaKPC, and blaSIM were present in the bacteria isolated from retail meat. The bacteria in the meat were separately sequenced and based on alignment, four different bacteria were identified. These findings suggest that bacteria found in retail meats are a reservoir for the spreading of ESBL blaVIM, blaBIC, blaKPC, and blaSIM resistance genes and bacteria strains.

• Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
• /
• v.32 no.1
• /
• pp.15-23
• /
• 2021

Background and Objectives During speech, the vocal folds oscillate at frequencies ranging from 100-200 Hz with amplitudes of a few millimeters. Mechanical stimulation is an essential factor which affects metabolism of human vocal folds. The effect of mechanical vibration on the cellular response in the human vocal fold fibroblasts cells (hVFFs) was evaluated. Materials and Method We created a culture systemic device capable of generating vibratory stimulations at human phonation frequencies. To establish optimal cell culture condition, cellular proliferation and viability assay was examined. Quantitative real time polymerase chain reaction was used to assess extracellular matrix (ECM) related and growth factors expression on response to changes in vibratory frequency and amplitude. Western blot was used to investigate ECM and inflammation-related transcription factor activation and its related cellular signaling transduction pathway. Results The cell viability was stable with vibratory stimulation within 24 h. A statistically significant increase of ECM genes (collagen type I alpha 1 and collagen type I alpha 2) and growth factor [transforming growth factor β1 (TGF-β1) and fibroblast growth factor 1 (FGF-1)] observe under the experimental conditions. Vibratory stimulation induced transcriptional activation of NF-κB by phosphorylation of p65 subunit through cellular Mitogen-activated protein kinases activation by extracellular signal regulated kinase and p38 mitogen-activated protein kinases (MAPKs) phosphorylation on hVFFs. Conclusion This study confirmed enhancing synthesis of collagen, TGF-β1 and FGF was testified by vibratory stimulation on hVFFs. This mechanism is thought to be due to the activation of NF-κB and MAPKs. Taken together, these results demonstrate that vibratory bioreactor may be a suitable alternative to hVFFs for studying vocal folds cellular response to vibratory vocalization.

• Journal of the Korean Society of Radiology
• /
• v.16 no.4
• /
• pp.381-386
• /
• 2022

Non-Destruction Test (NDT) is a method to check internal defects without destroying the product. Among them, radiographic testing (RT) uses high-energy radiation, so it is very important to prevent radiation exposure of workers. Therefore, in this study, in this study, a radiation sensor structure that improves radiation detection performance compared to the existing PbI₂ and can immediately detect accidents in RT was presented. For evaluation, the conversion efficiency was analyzed in the gamma ray source through FLUKA simulation. PbI₂ with overlapping Gd₂O₂S:Tb presented in this study showed a higher radiation sensitivity from 1.22 to 3.22 times than that of non-overlapping PbI₂. This indicates that the presented sensor is suitable for use as a radiation sensor for source detection in RT.

• Journal of the Korean Society of Radiology
• /
• v.81 no.5
• /
• pp.1151-1163
• /
• 2020

Purpose This study aimed to evaluate changes of subprosthetic pannus on cardiac CT and determine its relationship to echocardiographic findings in patients with mechanical aortic valve replacement (AVR). Materials and Methods Between April 2011 and November 2017, 17 AVR patients (56.8 ± 8.9 years, 12% male) who showed pannus formation on CT and had undergone both follow-up CT and echocardiography were included. The mean interval from AVR to the date of pannus detection was 10.5 ± 7.1 years. In the initial and follow-up CT and echocardiography, the pannus extent and echocardiographic parameters were compared using paired t-tests. The relationship between the opening angle of the prosthetic valve and the pannus extent was evaluated using Pearson correlation analysis. Results The pannus extent was significantly increased on CT (p < 0.05). The peak velocity (3.9 ± 0.8 m/s vs. 4.2 ± 0.8 m/s, p = 0.03) and mean pressure gradient (36.4 ± 15.5 mm Hg vs. 42.1 ± 15.8 mm Hg, p = 0.03) were significantly increased. The mean opening angles of the mechanical aortic leaflets were slightly decreased, but there was no statistical significance (73.1 ± 8.3° vs. 69.4 ± 12.1°, p = 0.12). The opening angle of the prosthetic leaflets was inversely correlated with the pannus extent (r = -0.57, p < 0.001). Conclusion The pannus extent increases over time, increasing transvalvular peak velocity and the pressure gradient. CT can be used to evaluate the pannus extent associated with hemodynamic changes that need to be managed by surgical intervention.