• Title/Summary/Keyword: 의미형성모델

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High fructose and high fat diet increased bone volume of trabecular and cortical bone in growing female rats (고과당 및 고지방 식이의 섭취가 성장기 동물모델의 골성장과 골성숙에 미치는 영향)

  • Ahn, Hyejin;Yoo, SooYeon;Park, Yoo-Kyoung
    • Journal of Nutrition and Health
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    • v.48 no.5
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    • pp.381-389
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    • 2015
  • Purpose: The objective of this study was to investigate the effects of a high fructose and fat diet on bone growth and maturation in growing female rats. Methods: Three-week-old female SD rats were randomly assigned to four experimental groups; the control group (CON: fed control diet based on AIN-93G, n = 8); the high-fructose diet group (HFrc: fed control diet with 30% fructose, n = 8); the high-fat diet group (Hfat: fed control diet with 45 kcal% fat, n = 8); and the high-fat diet plus high fructose group (HFrc + HFat: fed diets 45 kcal% fat with 30% fructose, n = 8). Each group was assigned their respective diets for the remaining eight weeks. Bone-related parameters (bone mineral density (BMD) and structural parameters, osteocalcin (OC), deoxypyridinoline (DPD)) and morphologic changes of kidney were analyzed at the end of the experiment. Results: Final body weights and weight gain were higher in the HFat and HFrc + HFat groups and showed higher tendency in the HFrc group compared with those of the CON group (p < 0.05); however, no significant difference in caloric intake was observed among the four experimental groups. The serum OC levels of the HFrc and HFrc + HFat groups were lower than those of the CON and HFat groups (p < 0.05). Urinary levels of DPD did not differ among the experimental groups. BV/TV and Tb.N of trabecular bone were higher in the HFrc + HFat group and showed a higher tendency in the HFrc group than those of the CON and HFat groups (p < 0.05). Tb.Pf of trabecular bone were lower in the HFrc + HFat group than those in the CON and HFat groups (p < 0.05). However, no difference in trabecular BMD was observed among the experimental groups. Cortical bone volume was higher in the HFat and HFrc + HFat groups than in the CON and HFrc groups (p < 0.05). No morphology change in kidney was observed among the experimental groups. Conclusion: Our study suggests that 8 weeks of high-fructose and high fat intake could improve the bone quality (Structural parameters) of trabecular and cortical bone of tibia in growing female rats.

Spectroscopic Analysis of Partially Folded State of Ubiquitin (유비퀴틴 단백질의 부분적으로 폴딩된 구조에 대한 분광학적 분석)

  • Park, Soon-Ho
    • Applied Biological Chemistry
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    • v.46 no.4
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    • pp.305-310
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    • 2003
  • Hydrophobic core variant of ubiquitin appeared to have partially folded structure at pH around 2. The intrinsic tryptophan fluorescence emission maximum of this ubiquitin variant at pH 2 showed slight blue shift compare to that of unfolded state, suggesting that some residual tertiary structures remain in this solvent condition. At the same solvent condition, this ubiquitin variant binds with hydrophobic dye, 8-anilinonaphthalene-1-sulfonic acid(AMS), which is known to bind to exposed hydrophobic surface. Furthermore, far-UV circular dichroic spectrum of this ubiquitin variant in the diminished pH was remarkably different from the far-UV CD spectrum of the native state or unfolded state. Based on the molar ellipticity at 220 nm, this ubiquitin variant at pH 2 appeared to have significant amount of secondary structures. All these observations suggest that this ubiquitin variant in the diminished solvent pH has loosely folded hydrophobic core with some secondary structures, which are key features of molten globule conformation. Since molten globule has long been considered as a protein folding intermediate, it is considered that this hydrophobic core variant ubiquitin will serve as a valuable model to study protein folding process.

Development of Line Density Index for the Quantification of Oceanic Thermal Fronts (해양의 수온전선 정량화를 위한 선밀도 지수 개발)

  • Cho, Hyun-Woo;Kim, Kye-Hyun
    • Journal of the Korean Association of Geographic Information Studies
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    • v.9 no.2
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    • pp.227-238
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    • 2006
  • Line density index(LDI) was developed to quantify a densely isothermal line rate as standard index in the ocean environment. Theoretical background on the LDI development process restricting index range 0 to 100 was described. And validation test was done for the LDI application condition that total line length is not greater than 1/10 of unit area. NOAA SST(Sea Surface Temperature) data were used for the experimental application of LDI in the South Sea of Korea. Using GIS, $0.1^{\circ}C$ isothermal lines were linearized as vector data form SST raster data, and unit area were built as polygon data. For the LDI calculation, spatial overlapping(line in polygon) was implemented. To analyze the effect of unit area size for the LDI distribution, two cases of unit area size were designed and descriptive statistics was calculated including performing normality test. The results showed no change of LDI's essential characteristics such as mean and normality except for the range of value, variance and standard deviation. Accordingly, it was found that complex structure of thermal front and even smaller scale of front width than unit area size could influence on the LDI distribution. Also, correlation analysis performed between LDI and difference of temperature(${\Delta}T^{\circ}C$), and horizontal thermal gradient(${\Delta}T^{\circ}C/km$) on the front was obtained from linear regression model. This obtained value was compared with the results from previous researches. Newly developed LDI can be used to compare the thermal front regions changing spatio-temporally in the ocean environment using absolute index value. It is considered to be significant to analyze the relationship between thermal front and marine environment or front and marine organisms in a quantitative approach described in this study.

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Exploring Secondary Students' Dialogic Argumentation Regarding Excretion via Collaborative Modeling (배설에 대한 협력적 모델링 과정에서 나타난 중학교 학생들의 대화적 논변활동 탐색)

  • Lee, Shinyoung;Kim, Hui-Baik
    • Journal of The Korean Association For Science Education
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    • v.37 no.6
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    • pp.1037-1049
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    • 2017
  • The purpose of this study is to explore how the flow of discourse move and their reasoning process in dialogic argumentation during group modeling on excretion. Five groups of three to four students in the second grade of a middle school participated in the modeling practice of a Gifted Center. Analysis was conducted on argumentation during the modeling activity in which students should explain how the waste product (ammonia) leaves the body. It was found that there was a sequential argumentative process-tentative consensus, solving the uncertainty, and consensus. There were several discourse moves - 'claim' and 'counterclaim' in the stage of tentative consensus, 'query' and 'clarification of meaning' in the stage of solving the uncertainty, and 'change of claim' in the stage of consensus. Students participated in the dialogic argumentation by constructing argument collaboratively for reaching a consensus. Critical questioning in the stage of solving the uncertainty and reasoning in the stage of consensus were the impact factors of dialogic argumentation. By answering the critical questions, students changed their claims or suggested new claims by defending or rebutting previous claims. Students justified group claims with diverse argumentation scheme and scientific reasoning to reach a group consensus. These findings have implication for science educators who want to adopt dialogic argumentation in science classes.

A Theoretical Study on Abduction as an Inquiry Method in Earth Science (지구과학의 한 탐구 방법으로서 귀추법에 대한 이론적 고찰)

  • Oh, Phil-Seok;Kim, Chan-Jong
    • Journal of The Korean Association For Science Education
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    • v.25 no.5
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    • pp.610-623
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    • 2005
  • This was a theoretical study of which the goal was to provide a foundation for developing and implementing earth science inquiry activities based on abduction as a scientific inquiry method. Through a review of relevant literature, the study examined the nature of earth science in terms of the goals of earth science inquiry and the characteristics of what is investigated in earth science. It also explored the forms and meanings of abduction, thinking strategies used in the abductive inference, and the abductive inquiry model. Abduction is the process of inferring certain rules (e.g., scientific facts, principles, laws) and providing explanatory statements or hypotheses in order to explain some phenomena. This method was found to be well-suited to the earth science inquiry which studies the causes and processes of natural phenomena in the earth and space environment. Abduction has the nature of ampliative, selective, evaluative, and creative inference, and several thinking strategies, including reconstruction of data, heuristic generalization, analogy, existential, conceptual combination, and elimination strategies, are employed for inferring rules and suggesting hypotheses. This study found the abductive inquiry model to be adaptable to earth science classrooms, and it is therefore suggested that earth science instructions should be based on the abductive method and that research work concerning the abductive inquiry in the classroom should follow.

Development of Rural Amenity Contents for the Textbooks of Agricultural High School (농업계고등학교 교과서의 어메니티 교육내용 개발)

  • Kim, Eun-Ja;Ryu, Cheong-San;Kang, Bang-Hun;Yoon, Soon-Duck;Kim, Sang-Bum;Hwang, Jeong-Im;Rhee, Sang-Young
    • Proceedings of the Korean Society of Community Living Science Conference
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    • 2009.09a
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    • pp.94-94
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    • 2009
  • 농업계고등학교 교과서는 농촌어메니티를 학습할 수 있는 최적의 교재로서 농촌어메니티 교육내용을 개발함으로써 청소년의 올바른 농업 농촌 가치관 형성 및 국민적 공감대 확산에 이바지하고자 한다. 대상 교과서는 농업계고등학교 교과서 39종으로 이루어졌으며, 연구방법으로는 우선적으로 1~5단계의 내용분석 척도를 설정하여(1단계는 어메니티 개념에 따라 반드시 수정이 필요한 내용, 2단계는 어메니티 개념에 따라 수정이 필요한 내용, 3단계는 어메내티 개념이 포함되었는지 판단할 때 크게 문제가 없는 내용, 4단계는 어메니티 개념이 포함되어 있는 좋은 내용, 5단계는 어메니티 개념이 포함되어 있는 교과서의 모델이 될 수 있는 내용) 판정하였다. 그 결과 1단계 어메니티 개념에 따라 반드시 수정이 필요한 내용을 선정하여 교과내용을 개발하였으며, 이는 어메니티 관점에 맞추어 실시하였다. 또한 내용분석을 통한 교과서 구분을 하여 A, B, C 유형으로 나타내었다. A유형은 내용분석의 결과 판정 1 또는 2의 분석 내용이 20개 이상 나온 교과서, B유형은 내용분석의 결과 판정 1 또는 2의 분석 내용이 10~19개 나온 교과서, C유형은 내용분석의 결과 평정 1또는 2의 분석 내용이 10개 미만으로 나온 교과서를 의미한다. 교과내용 개발 결과 총 262건의 교과내용 개발이 이루어졌으며, 문장 132개로 50.38%, 사진 105개 40.47%, 삽화 22개 8.35, 그래프 0.76%, 표 0.38% 등의 순서로 나타났다. 총 262개 개발내용중에서 '사회자원의 시설'부분에 대한 관점 77개로, '사회자원의 경제활동'에 대한 관점 64개, '문화자원의 경관'에 대한 관점 50개 순으로 집계되었다. 그 다음은 '자연자원의 자연'에 대한 관점이 47개, 문화자원의 역사'에 대한 관점이 9개, '사회자원의 공동체 활동'에 대한 관점이 14개 순으로 나타났다. 자연적 자원 18.31%, 문화적 자원 22,52%, 사회적 자원 관점이 59.16%로 '사회적 자원 관점이 가장 많은 것으로 나타났다. 이는 농업계고등학교 교과서에서는 농촌어메니티의 사회적 자원이 강조되어야 하며, 문화적 자원, 자연적 자원의 순서로 강조될 필요성이 있다는 것을 뜻한다. 즉 농촌어메니티개념의 확립을 이하여 현재 농업계 고등학교 교과서에서는 시설, 경제활동, 공동체활동 같은 '사회적 자원'을 보강하여 강조할 필요가 있음을 나타낸다.

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Visualization of Malwares for Classification Through Deep Learning (딥러닝 기술을 활용한 멀웨어 분류를 위한 이미지화 기법)

  • Kim, Hyeonggyeom;Han, Seokmin;Lee, Suchul;Lee, Jun-Rak
    • Journal of Internet Computing and Services
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    • v.19 no.5
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    • pp.67-75
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    • 2018
  • According to Symantec's Internet Security Threat Report(2018), Internet security threats such as Cryptojackings, Ransomwares, and Mobile malwares are rapidly increasing and diversifying. It means that detection of malwares requires not only the detection accuracy but also versatility. In the past, malware detection technology focused on qualitative performance due to the problems such as encryption and obfuscation. However, nowadays, considering the diversity of malware, versatility is required in detecting various malwares. Additionally the optimization is required in terms of computing power for detecting malware. In this paper, we present Stream Order(SO)-CNN and Incremental Coordinate(IC)-CNN, which are malware detection schemes using CNN(Convolutional Neural Network) that effectively detect intelligent and diversified malwares. The proposed methods visualize each malware binary file onto a fixed sized image. The visualized malware binaries are learned through GoogLeNet to form a deep learning model. Our model detects and classifies malwares. The proposed method reveals better performance than the conventional method.

A Study on Negligence of Data Modeling Fundamentals at the University Job Information System (대학 취업정보시스템에서 데이터모델링 기본이론 경시에 관한 연구)

  • Rhee, Hae-Kyung;Kim, Hee-Wan
    • Journal of the Korea Society of Computer and Information
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    • v.19 no.8
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    • pp.139-150
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    • 2014
  • In this essay, we hoped to see how the operational university job database systems perform badly, since there are a lot of signs that they fall short of data design fundamentals. Fortunately, we are able to choose a university employment support database(UESD) application as a candidate for our study. We have taken UESD system as it is and we have developed an enhanced version of the UESD system, which strictly followed the basic fundamentals in data modeling and named it as NewUESD system. Then, we have conducted a comparison to see how much UESD system is deviated from the standard balancedness found in NewUESD. From the perspective of data obesity, we computed how much UESD contains unnecessary data. The NewUESD contained no unnecessary data at all, which implies that it has only data that is necessary to form a data model. But the data obesity of UESD system is found to be more than 50%. Therefore, it is significantly higher, 37% higher in this case, than the obesity judged to be normal, which is 19% in NewUESD system.

Income led growth in Korea: issues, implications and roles (소득주도 성장의 평가와 향후 방향)

  • Kim, Taeil
    • 한국사회정책
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    • v.25 no.3
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    • pp.175-208
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    • 2018
  • The purpose of this article is to evaluate Korea's income-led growth policy that is still in dispute. To do this, I discussed the content, background and implications of the income-led growth theory. Next, I discussed the role of income-led growth as a growth strategy in the Korean economy. The income-led growth theory comes from the Keynesian tradition which emphasizes the role of demand in the economic growth. The basic idea emerged nearly 80 years ago, and the current model emerged about 30 years ago. Some of the Korean researchers began to pay attention to this issue when ILO researchers discussed it in 2010. The recent emphasis on income-led growth theory was due to the tendency of declining labor income, thus forming a consensus that increasing inequality can hamper growth. The effectiveness of the income-led growth strategy, which can lead to economic growth by increasing the share of labor income, is theoretically and empirically controversial. However, it is understandable why income-led growth strategies have emerged. Income-led growth is not a short-term strategy nor a key of growth strategy. However, in current socio economic structures, the prescriptions of income-led growth theory is meaningful in that it enables sustainable growth by making the economic system healthy. In addition, unlike the West, the government's welfare expenditure can play a significant role as part of the income-led growth prescriptions in Korea.

A Study on the Effects of Self-support Program Participants' Social Capital on Their Quality of Life - Focusing on the mediating effect of job satisfaction - (자활사업 참여자의 사회적 자본이 삶의 질에 미치는 영향에 관한 연구 - 직무만족의 매개효과를 중심으로 -)

  • Lee, Mi-Ra
    • Korean Journal of Social Welfare Studies
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    • v.42 no.4
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    • pp.413-443
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    • 2011
  • The objectives of this study were to survey the level of social capital owned by self-support program participants, and to analyze the direct and indirect effects of social capital on their quality of life. Particularly because an individual's life is highly likely to be influenced by multiple aspects including human relation, this study purposed to determine the mediating effect of job satisfaction in the relation between social capital and the quality of life. The survey used a structured questionnaire, and in the contents of the questionnaire, the quality of life was selected as a dependent variable, social capital as an independent variable, and the job satisfaction as a mediating variable affecting the relation between social capital and the quality of life. The results of this study were as follows. First, as to the relation between self-support program participants' social capital and the quality of life, the network level and the normative level hand an important effect on the quality of life. Second, as to the relation between self-support program participants' social capital and job satisfaction, social capital had a negative effect on job satisfaction. Third, in the relation between self-support program participants' social capital and their quality of life, the mediating effect of job satisfaction was positive and this supports the spillover model among hypotheses on the relation between job satisfaction and the quality of life.