• The Journal of the Acoustical Society of Korea
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• v.31 no.3
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• pp.151-160
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• 2012

In medical ultrasound imaging, elasticity imaging helps to diagnose tumors such as cancer. This paper is concerned with the application of acoustic radiation force to soft tissue of interest to implement elasticity imaging. In order to reduce the data acquisition time, instead of relying on transmit focusing, a plane wave of burst type is transmitted to apply the acoustic radiation force simultaneously to an entire imaging region to be observed. A homogeneous phantom experiment confirms that increasing the transmit excitation duration instead of employing transmit focusing generates a high enough acoustic radiation force to obtain elasticity images. It is found, however, that a different displacement versus time characteristic is observed unlike the case of using a conventional focused acoustic radiation force. Experimental results obtained through the use of an ultrasound phantom and a bovine liver show that lesions can be correctly differentiated.

• The Journal of the Acoustical Society of Korea
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• v.6 no.3
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• pp.5-16
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• 1987

In this paper, the sound radiation from a clamped circular plate with a viscoelastic layer excited by impact force is studied both analytically and experimentally. The composite plate vibrations are obtained by using the normal mode analysis and the eigenvalues are obtained by a Mindlin plate theory including the rotary inertia and shear deformation, The contact force developed between the ball and the plate with attached layers is obtained by Hertz contact theory. The radiated sound pressure is calculated by the Rayleigh integral. Prediction of the waveforms of sound radiating from the plate with attached layers and a method for reducing noise generation from the plate by impact force are also shown in this paper.

• The Journal of the Acoustical Society of Korea
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• v.31 no.6
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• pp.399-409
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• 2012

In this paper we propose a method for measuring the shear modulus of an ultrasound soft tissue phantom using an acoustic radiation force. The proposed method quantitatively determines the shear modulus based on the rise time of a displacement induced by an acoustic radiation force at the focal point of a focused ultrasound beam. The shear wave speed and shear modulus obtained from the proposed method and a shear wave propagation method were compared to verify the validity of the proposed method. In the shear wave propagation method, the shear modulus is first computed by measuring the propagating speed of a shear wave induced in a phantom by a limited-diffraction transmit field, and then was compared to that obtained with the proposed method in an ultrasound data acquisition system calibrated based on the first computed shear modulus. The relative errors between the two methods were found to be 4% for shear wave speed and less than 9% for shear modulus, confirming the usefulness of the proposed method.

• Journal of the Korean Society for Nondestructive Testing
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• v.32 no.5
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• pp.573-584
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• 2012

Breast and prostate tumors or cancers tend to be stiffer than the surrounding normal tissue. However, the difference in echogenicity between cancerous and normal tissues is not clearly distinguishable in ultrasound B-mode imaging. Thus, imaging the stiffness contrast between the two different tissue types helps to diagnose lesions quantitatively, and such a method of imaging the elasticity of human tissue is termed ultrasound elasticity imaging. Recently, elasticity imaging has become an effective complementary diagnostic modality along with ultrasound B-mode imaging. This paper presents various elasticity imaging methods that have been reported up to now and describes their characteristics and principles of operation.

• The Korean Journal of Applied Statistics
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• v.28 no.2
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• pp.201-210
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• 2015

Repeated measurements on each variables of interest often arise in bioscience or medical research. We need to account for correlations among repeated measurements to assess the correlation between two variables in the presence of replication. This paper reviews methods to estimate a correlation coefficient between two variables in repeated measurements using the variance-covariance matrix of linear mixed effect models. We analyze acoustic radiation force impulse imaging (ARFI) data to assess correlation between three shear wave velocity (SWV) measurements in liver or spleen and spleen length by ultrasonography. We present how to obtain parameter estimates for the variance-covariance matrix and correlations in mixed effects models using PROC MIXED in SAS.