• Title/Summary/Keyword: 은혜

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Prediction of Pumping Efficacy of Left Ventricular Assist Device according to the Severity of Heart Failure: Simulation Study (심실의 부하감소 측면에서 좌심실 보조장치의 최적 치료시기 예측을 위한 시뮬레이션 연구)

  • Kim, Eun-Hye;Lim, Ki Moo
    • Journal of the Korean Society of Manufacturing Process Engineers
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    • v.12 no.4
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    • pp.22-28
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    • 2013
  • It is important to begin left ventricular assist device (LVAD) treatment at appropriate time for heart failure patients who expect cardiac recovery after the therapy. In order to predict the optimal timing of LVAD implantation, we predicted pumping efficacy of LVAD according to the severity of heart failure theoretically. We used LVAD-implanted cardiovascular system model which consist of 8 Windkessel compartments for the simulation study. The time-varying compliance theory was used to simulate ventricular pumping function in the model. The ventricular systolic dysfunction was implemented by increasing the end-systolic ventricular compliance. Using the mathematical model, we predicted cardiac responses such as left ventricular peak pressure, cardiac output, ejection fraction, and stroke work according to the severity of ventricular systolic dysfunction under the treatments of continuous and pulsatile LVAD. Left ventricular peak pressure, which indicates the ventricular loading condition, decreased maximally at the 1st level heart-failure under pulsatile LVAD therapy and 2nd level heart-failure under continuous LVAD therapy. We conclude that optimal timing for pulsatile LVAD treatment is 1st level heart-failure and for continuous LVAD treatment is 2nd level heart-failure when considering LVAD treatment as "bridge to recovery".

A Case of Extensive Cerebral Venous Thrombosis in Childhood Nephrotic Syndrome (신증후군 환아에서 발생한 광범위한 뇌정맥 혈전증 1례)

  • Son, Chang-Hee;Lee, Eun-Hye;Lee, Joo-Hoon;Park, Young-Seo
    • Childhood Kidney Diseases
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    • v.10 no.2
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    • pp.238-243
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    • 2006
  • Nephrotic syndrome in childhood is known to be associated with a hypercoagulable state and thromboembolic complications, among which cerebral venous thrombosis is a very rare and serious one, with only a few isolated reports in the literature. A 9-year-old boy with known nephrotic syndrome was admitted due to a relapse with massive proteinuria and generalized edema. He complained of a prolonged frontal headache. The enhanced brain magnetic resonance imaging(MRI) showed a high signal in the region of the superior sagittal sinus and right transverse sinus consistent with a thrombus. He was managed with steroids, cyclosporine and warfarin. His headache subsided 2 weeks later and proteinuria resolved 1 month later. An MRI 2 months later was normal. We describe this case and review the literature to emphasize the importance of recognizing this potentially life threatening complication and initiating anticoagulation therapy.

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Cultural Knowledge, Empathy and Cultural Sensitivity of University Students Majoring in Health And Welfare (보건의료 및 복지 전공 대학생의 다문화 지식, 공감, 문화적 민감성에 관한 연구)

  • Oh, Won-Oak;Jung, Woo-Sik;Kang, Hyung-Gon;Kim, Eun-Hye;Suk, Min-Hyun
    • Journal of the Korean Society of School Health
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    • v.23 no.2
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    • pp.192-199
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    • 2010
  • Purpose: Multi-cultural families are increasing highly in Korea. Health care professionals and students majoring in health and welfare need to develop their cultural competence for quality of life from multi-cultural families. This study was to be conducted by examining the level of culture knowledge, empathy, and cultural sensitivity of university students majoring in health and welfare. Methods: Convenience sampling method was used and 408 students from 3 universities were evaluated for final analysis. Data collection was conducted through the use of questionnaires. Results: The score of cultural knowledge of students was very low. Empathy and cultural sensitivity showed middle range. There was a significant correlation between cultural knowledge and empathy, empathy and cultural sensitivity. However, there was no significant correlations between cultural knowledge and cultural sensitivity. Conclusion: An understanding of multi-cultural enables health and welfare providers to specialize service in cross- cultural situations of multi-cultural families in Korea. Ways to improve cultural competence for students majoring in health care and welfare is needed.

Mutagenicity Studies on Nonspecific Immunostimulator BARODON® (비특이 면역증강제 BARODON®에 대한 유전독성시험)

  • 서민수;조성대;안남식;정지원;양세란;박준석;박기수;홍인선;조은혜
    • Toxicological Research
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    • v.19 no.2
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    • pp.141-146
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    • 2003
  • A nonspecific immunostimulator $BARODON^{\circledR}$ was tested for mutagenicity using Ames Salmonella tester strains TA98, TA1 00, TA 102, TA 1535 and TA 1537 with or without metabolic activation (59 mix). None of the fresh species showed mutagenicity. In the reverse mutation test using Salmonella phimurium TA98, TA100, TA102, TA1535 and TA1537 did not increase the number of revertants at all doses tested (5, 2.5 or 1.25 mg/ml). Chromosome aberration test was carried out in Chinese hamster lung (CHL) cell line. The cells were treated with $BARODON^{\circledR}$ (1, 0.5 or 0.25 mg/ml), while positive control group was treated with Mitomycin C (0.1 mg/ml). The results show that there is no statistically significant difference between positive control and treatment groups. In mouse micronucleus test, there was significant increase in the ratio of micronucleated polychromatic erythrocyte (MNPCE) in the high dose group (10% $BARODON^{\circledR}$), while there is no significance between control and low (2.5% $BARODON^{\circledR}$) or middle (5% $BARODON^{\circledR}$ dose groups. Taken together, this results suggest that below 5% $BARODON^{\circledR}$ might not have mutagenic potential in vitro and vivo systems.

Consistency of ANS Responses Induced by Emotions and Emotion-Specific ANS Responses (정서에 의해 유발된 자율신경계 반응의 일관성 및 정서.특정적 자율 신경계 반응 패턴 확인)

  • 이경화;장은혜;석지아;손진훈;방석원;김경환;이미희
    • Proceedings of the Korean Society for Emotion and Sensibility Conference
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    • 2001.11a
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    • pp.104-111
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    • 2001
  • 정서와 생리반응 (자율신경계 반응) 간의 관계에 관하여 성인을 대상으로 최근가지 많은 연구가 행해져 왔다. 본 연구에서는 동일한 실험참여자를 대상으로 일정 기간 동안 여러 회의 반복실험을 통해 정서(기쁨, 슬픔, 분노, 공포, 혐오)에 따른 자율신경계의 반응의 일관성과 정서별 자율신경계 반응 패턴을 규명하고자 하였다. 본 실험에 앞서 저서를 유발하기 우한 도구인 정서유발자극세트와 정서에 대한 심리반응을 평가하기 위한 정서평가척도가 제작되었다. 정서유발자극세트는 2-4분 정도의 각 정서 장면이 포함된 총 5개의 동영상 장면들이다. 예비실험을 통해 70% 이상의 적합성 및 효과성을 가진 4개의 세트를 추출하여 본 실험에 사용하였다. 본 실험은 남녀 대학생 12명을 대상으로 4회 반복해서 실시되었다. 실험참여자들은 각 정서 장면을 시청 후, 유발된 정서에 대한 심리적인 평가를 하였다. 측정한 자율신경계 생리반응 변수는 ECG, PPG, EDA, SKT이었다. 연구 결과, 심리반응에서 정서유발자극세트는 75% 이상의 적합성 및 효과성을 보였다. 생리반응(ECG, EDA) 분석 결과, 정서에 따른 자율신경계 반응은 회기별로 일관적이었으며, 각 정서별로 특정적인 생리반응 패턴을 가지는 것으로 나타났다.

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Isolation and Characterization of Bacteriolytic Wild Myxobacteria (용균성 야생 점액세균의 분리)

  • 박수연;이봉수;김지훈;이차율;장은혜;조경연
    • Microbiology and Biotechnology Letters
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    • v.32 no.3
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    • pp.218-223
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    • 2004
  • Myxobacteria are Gram-negative soil bacteria known to be a rich source of potentially useful secondary metabolites. We have isolated 204 strains of bacteriolytic myxobacteria from soil samples collected in Korea and determined their 16S rRNA sequences. Sequence analysis of the partially determined 16S rRNA sequences has suggested that 132 isolates (65% of total isolates) belong to the genus Myxococcus and 59 isolates (29% of total isolates) belong to the genus Corallococcus. Meanwhile, 4 isolates appear to be Archangium spp. and the other 4 isolates appear to be Stigmatella spp. Genera of the remained 5 isolates have not been identified because their 16S rRNA sequences are distantly related to those of known myxobacteria.

Detection of Implicit Walking Intention for Walking-assistant Robot Based on Analysis of Bio/Kinesthetic Sensor Signals (보행보조로봇을 위한 다중 생체/역학 센서의 신호 분석 및 사용자 의도 감지)

  • Jang, Eun-Hye;Chun, Byung-Tae;Chi, Su-Young;Lee, Jae-Yeon;Cho, Young-Jo
    • The Journal of Korea Robotics Society
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    • v.5 no.4
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    • pp.294-301
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    • 2010
  • In order to produce a convenient robot for the aged and the lower limb disabled, it is needed for the research detecting implicit walking intention and controlling robot by a user's intention. In this study, we developed sensor module system to control the walking- assist robot using FSR sensor and tilt sensor, and analyzed the signals being acquired from two sensors. The sensor module system consisted of the assist device control unit, communication unit by wire/wireless, information collection unit, information operation unit, and information processing PC which handles integrated processing of assist device control. The FSR sensors attached user's the palm and the soles of foot are sensing force/pressure signals from these areas and are used for detecting the walking intention and states. The tilt sensor acquires roll and pitch signal from area of vertebrae lumbales and reflects the pose of the upper limb. We could recognize the more detailed user's walking intention such as 'start walking', 'start of right or left foot forward', and 'stop walking' by the combination of FSR and tilt signals can recognize.

Study on Spatio-Temporal Eye-Hand Coordination in Targeting Tasks (지시운동 수행동안 안구와 손의 시공간적 협응에 관한 연구)

  • Eun, H.I.;Yu, M.;Lee, A.R.;Kim, D.W.;Kwon, T.K.;Kim, N.G.
    • Journal of Biomedical Engineering Research
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    • v.28 no.3
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    • pp.417-422
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    • 2007
  • In this study, we investigated spatio-temporal eye-hand coordination by the "Global effect paradigm", a target-distracter configuration Global effect is observed a variety of visual tasks, for example, during rapid automatic tracking, scanning for target detail, and the comparison of target configurations. Global effect used to investigate eye-hand coordination with a task that presents a target close to a distracter. Eight young subjects participated in the experiments. The experiments consist of using a distracter less eccentric than the targe1 and using a distracter more eccentric than target. Each experiment consist of tasks which are making reference, pointing the target with watching visual stimulation(saccade) and pointing the target. The subject's task was to move towards the target as quickly as possible. We measured the eye movement by using EOG and the hand movement by using NDI Optotrak system. This study shows that eye and hand movement exists for global effect paradigm in spatio-temporal coordination.

A Comparative Study of Korean and Australian Women's Hairstyle Behavior and Preference (한국과 호주여성의 헤어스타일 행동 및 선호도 비교)

  • Park, Sook-Hyun;Ryu, Eun-Hye;Lee, Soon-Deuk
    • Korean Journal of Human Ecology
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    • v.15 no.1
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    • pp.129-139
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    • 2006
  • The purpose of this study is to compare the hairstyles between Korean and Australian women, who have different individual hair characteristics, social backgrounds, and culture from each other. Data were collected through a survey of 208 Australian females and 392 Koreans. Frequency analysis, t-test, and two-way ANOVA were used to analyze the data. The results are as follows: Korean and Australian women maintain a hairstyle for six months or less in most of the cases. They preferred a hairstyle with bang, and the elderly especially a shorter hair length. Choosing their hairstyles depended on such factors as hair length, dyeing, form of face, harmony with clothing, and social status. There was no difference, however, in a preferred hair length. Korean women possessed brown and black hair colors in a descending order, whereas Australians light blonde and brown in a descending order as well. There was a big difference in the preference for a permanent wave. Korean women preferred to give a volume or curl to their hair, while Australians wanted to have a straight hair. According to the study on a hairstyle behavior, it was found that there were differences in fashion and individuality between two countries and also in dependency among age groups, whereas no differences existed in beauty.

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A Case Report of FOLFIRI-Induced Diarrhea in Patient with Metastatic Rectal Cancer Treated with Modified Wiryeong-tang (전이 직장암 환자의 FOLFIRI 유발 설사에 위령탕 가감방 치험 1례)

  • Yoon, Sung Soo;Kim, Eun Hye;Lee, Jee Young;Yoon, Seong Woo
    • Journal of Korean Traditional Oncology
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    • v.23 no.1
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    • pp.15-21
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    • 2018
  • Objectives : This study was aimed to describe a case of a patient with FOLFIRI-induced diarrhea, which was improved by treatment with Korean herbal medicine, modified Wiryeong-tang. Methods : The patient with metastatic rectal cancer recieved FOLFIRI plus bevacizumab as a palliative chemotherapy and showed repetitive diarrhea despite administration of loperamide, which was treated with modified Wiryeong-tang. To evaluate the effect of the treatment, the Bristol Stool Form Scale and bowel movement frequency were checked. Results : During the treatment, the stool form using Bristol Stool Form Scale was improved from diarrhea to normal stool, and the bowel movement frequency was decreased. Conclusions : The result suggest that modified Wiryeong-tang may be an effective treatment for FOLFIRI-induced diarrhea.