• Title/Summary/Keyword: 유전체분석

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Complete genome sequence of Pseudoalteromonas donghaensis HJ51T isolated from seawater (해수에서 분리된 Pseudoalteromonas donghaensis HJ51T 의 유전체 서열분석)

  • Oh, Ji-Sung;Roh, Dong-Hyun
    • Korean Journal of Microbiology
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    • v.54 no.3
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    • pp.305-307
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    • 2018
  • The whole genome sequencing using PacBio RS II platform was performed for a marine bacterium Pseudoalteromonas donghaensis $HJ51^T$ isolated from East Sea of Korea. As a result, three assembled contigs consisting of a chromosome (size of 3,646,857 bp, and G + C content of 41.8%) and two plasmids (size of 842,855 bp and 244,204 bp, and G + C content of 41.3% and 40.4%, respectively) were obtained. The genome included 4,083 protein coding genes and 127 RNA genes. This result could be used for gene sources of biopolymers degradation and the development as a new host with secretion system similar to Escherichia coli.

Draft genome sequence of Streptococcus sp. strain NM isolated from head and neck cancer patients (두경부암 환자로부터 분리된 Streptococcus sp. strain NM의 유전체분석)

  • Kim, Young Suk;Do, Kyoung-Tag;Park, Soo-Je
    • Korean Journal of Microbiology
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    • v.55 no.1
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    • pp.61-63
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    • 2019
  • Streptococcus sp. strain NM belonging to Firmicutes was isolated from head and neck cancer patients. Here, we report the draft genome sequence of strain NM with a size of approximately 1.90 Mbp and a mean G+C content of 39.3%. The draft genome included 1,845 coding sequences, and 12 ribosomal RNA and 58 transfer RNA genes. In the draft genome, genes involved in the antimicrobial resistance, hemolysis and defense system have been identified.

유전체공진기용 마이크로웨이브 세라믹스 기술

  • Lee, Jae-Sin;Seong, Hui-Gyeong;Kim, Tae-Heung;Choe, Tae-Gu
    • Electronics and Telecommunications Trends
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    • v.7 no.2
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    • pp.63-78
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    • 1992
  • 이동통신 및 위성방송등 마이크로웨이브를 이용하는 통신시스팀의 보급이 활발하게 진척됨에 따라 마이크로웨이브 대역에서 동작하는 부품의 산업적 중요성이 부각되고 있다. 여러가지 고주파통신용 부품들 중에서 유전체공진기를 이용한 RF 및 마이크로웨이브 필터와 진동자는 이들 부품의 소형화에 크게 기여하고 있다. 본 분석에서는 유전체 공진기의 소재로 이용되는 마이크로웨이브 세라믹스 및 그 응용부품의 발전과정을 간단히 살펴보았다. 또한 마이크로웨이브 유전체 소재에 대한 특성변수의 중요성을 검토하고, 세라믹 소재기술에 대하여 살펴본 다음 향후 고주파필터 부품개발과 관련한 마이크로웨이브 세라믹스 개발방향을 제시하였다.

Compact Triple-Mode Bandpass Filter Using a Cylindrical Dielectric Resonator (원통형 삼중모드 유전체 공진기를 이용한 대역 통과 여파기의 설계)

  • Jang, Geon-Ho;Park, Nam-Shin;Kim, Byung-Chul;Lee, Don-Yong;Won, Jung-Hee;Wang, Xu-Guang
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.26 no.1
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    • pp.30-38
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    • 2015
  • In this paper, the design of a compact triple-mode bandpass filter using a high-Q cylindrical dielectric resonator is proposed. In detail, the triple $TE_{01{\delta}}$ modes along three orthogonal axes are used and novel coupling structure in the metallic enclosure is adopted to introduce the coupling between the resonant modes. Due to the cross coupling, the proposed bandpass filter has an asymmetric frequency response with flexible three transmission zeros, one of which can be located very close to the passband edge to provide an extremely sharp skirt characteristic with low insertion loss. The proposed filter is about 60 % miniaturized compared with conventional single-mode dielectric resonator filter. The proposed bandpass filter design is validated by the circuit and 3D EM simulations and measurements compared to the target specifications.

Study on Genetic Evaluation using Genomic Information in Animal Breeding - Simulation Study for Estimation of Marker Effects (가축 유전체정보 활용 종축 유전능력 평가 연구 - 표지인자 효과 추정 모의실험)

  • Cho, Chung-Il;Lee, Deuk-Hwan
    • Journal of Animal Science and Technology
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    • v.53 no.1
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    • pp.1-6
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    • 2011
  • This simulation study was performed to investigate the accuracy of the estimated breeding value by using genomic information (GEBV) by way of Bayesian framework. Genomic information by way of single nucleotide polymorphism (SNP) from a chromosome with length of 100cM were simulated with different marker distance (0.1cM, 0.5cM), heritabilities (0.1, 0.5) and half sibs families (20 heads, 4 heads). For generating the simulated population in which animals were inferred to genomic polymorphism, we assumed that the number of quantitative trait loci (QTL) were equal with the number of no effect markers. The positions of markers and QTLs were located with even and scatter distances, respectively. The accuracies of estimated breeding values by way of indicating correlations between true and estimated breeding values were compared on several cases of marker distances, heritabilities and family sizes. The accuracies of breeding values on animals only having genomic information were 0.87 and 0.81 in marker distances of 0.1cM and 0.5cM, respectively. These accuracies were shown to be influenced by heritabilities (0.87 at $h^2$ =0.10, 0.94 at $h^2$ =0.50). According to half sibs' family size, these accuracies were 0.87 and 0.84 in family size of 20 and 4, respectively. As half sibs family size is high, accuracy of breeding appeared high. Based on the results of this study it is concluded that the amount of marker information, heritability and family size would influence the accuracy of the estimated breeding values in genomic selection methodology for animal breeding.

Reconstruction of Metabolic Pathway for the Chicken Genome (닭 특이 대사 경로 재확립)

  • Kim, Woon-Su;Lee, Se-Young;Park, Hye-Sun;Baik, Woon-Kee;Lee, Jun-Heon;Seo, Seong-Won
    • Korean Journal of Poultry Science
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    • v.37 no.3
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    • pp.275-282
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    • 2010
  • Chicken is an important livestock as a valuable biomedical model as well as food for human, and there is a strong rationale for improving our understanding on metabolism and physiology of this organism. The first draft of chicken genome assembly was released in 2004, which enables elaboration on the linkage between genetic and metabolic traits of chicken. The objectives of this study were thus to reconstruct metabolic pathway of the chicken genome and to construct a chicken specific pathway genome database (PGDB). We developed a comprehensive genome database for chicken by integrating all the known annotations for chicken genes and proteins using a pipeline written in Perl. Based on the comprehensive genome annotations, metabolic pathways of the chicken genome were reconstructed using the PathoLogic algorithm in Pathway Tools software. We identified a total of 212 metabolic pathways, 2,709 enzymes, 71 transporters, 1,698 enzymatic reactions, 8 transport reactions, and 1,360 compounds in the current chicken genome build, Gallus_gallus-2.1. Comparative metabolic analysis with the human, mouse and cattle genomes revealed that core metabolic pathways are highly conserved in the chicken genome. It was indicated the quality of assembly and annotations of the chicken genome need to be improved and more researches are required for improving our understanding on function of genes and metabolic pathways of avian species. We conclude that the chicken PGDB is useful for studies on avian and chicken metabolism and provides a platform for comparative genomic and metabolic analysis of animal biology and biomedicine.

Technical Trend NRD(Nonradiative Dielectric) Waveguide (NRD(Nonradiative Dielectric) 도파로의 기술 개발 동향)

  • Kim, D.Y.;Hahn, J.W.;Jun, B.H.;Lee, S.S.
    • Electronics and Telecommunications Trends
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    • v.14 no.5 s.59
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    • pp.34-41
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    • 1999
  • NRD(Nonradiative Dielectric) 도파로는 평행한 평판 전도체 사이에 유전체가 삽입된 간단한 구조를 가지는 도파로로 유전체 도파로의 불연속부나 벤딩(bending)에서 발생되는 복사신호를 평행평판 도파로의 차단 주파수 특성으로 인해 효과적으로 억압할 수 있으며, 유전체 도파로가 갖는 저 손실 특성을 이용하여 신호를 손실 없이 전송할 수 있기 때문에 밀리미터파 응용시스템에 적용 가능한 신기술로 널리 연구되어 지고 있다. 본 고에서는 이러한 NRD 도파로의 기본적인 동작원리에 대해서 알아보고 또한 NRD 도파로의 기술개발 동향에 대해서 정리하였다.

Current status of Brassica rapa functional genome research in Korea (한국 배추 기능유전체 연구의 현황)

  • Yu, Jae-Gyeong;Park, Ji-Hyun;Park, Young-Doo
    • Journal of Plant Biotechnology
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    • v.37 no.2
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    • pp.166-173
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    • 2010
  • The purpose of functional genome research is to identify biological function of useful gene and to give an agricultural value in plant biotechnology. Brassica rapa is an economic crop which recorded 1,000 billion won of domestic market and 100 million dollar of exports and it produces 2.5 million ton in 50,000 ha as a major ingredient of representative Korean food, Kimchi. Furthermore, it is very important crop economically and commercially because Korea is major seed exporter. The fact that Multinational Brassica Genome Project (MBGP) was launched and Arabidopsis thaliana, affiliated to same genus with B. rapa, has been fully sequenced activated functional genome research of B. rapa. Besides new technologies related to gene function analysis keep developing, many results are reporting every year by international research including Korea. This review paper introduces development of Chinese cabbage mutants which is a first step in functional genome research, variant phenotypes of mutants, flanking DNA analysis in B. rapa genome, gene identification, gene analysis using microarray, and representative researches.