• Title/Summary/Keyword: 유전적 하중

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The Study About Intra-Familial Transmission of the Neurological Soft Signs in Schizophrenia (정신분열병에서 연성 신경학적 징후의 가족내 전달에 관한 연구)

  • Yoo, Sujung;Choi, Yongrak;Lee, Sangick;Shin, Chuljin;Kim, Siekyeong;Son, Jungwoo
    • Korean Journal of Biological Psychiatry
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    • v.15 no.2
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    • pp.83-91
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    • 2008
  • Objectives : Neurological soft signs have been regarded as endophenotypes associated with the genetic basis of schizophrenia. This study was to investigate the intra-familial correlations of the neurological soft signs according to their genetic loading. Methods : Schizophrenic patients(N=14) were included, who had one parent with a family history of schizophrenia and the other without it. Genetic loading was determined by the patient's family history of schizophrenia using the Family Interview for Genetic Studies(FIGS). These parents were subdivided into two groups. The first group was designated as 'presumed carriers'(N=9) of genetic loading, who had one or more schizophreic firstor second-degree relatives. The second group was designated as 'presumed non-carriers'(N=11) of genetic loading, who had no schizophrenic first- or second-degree relatives. Normal controls(N=12) consisted of people without schizophrenic relatives. NSS were evaluated using the Neurological Evaluation Scale-Korean Version (NES-K), and the intra-familial correlations of NSS were tested using the Intra-Class Coefficients(ICC) method. Results : The scores of Motor Coordination subdimension of NES-K were significantly correlated between the patients and their presumed carriers(ICC=.804, p=.016), but not significantly correlated between the patients and their presumed noncarriers. In other subdimensions of NES-K, no significant correlation were found between the patients and their parents regardless of the genetic loading. But, there were no statistically significant differences in the scores of Motor Coordination subdimension of NES-K between the patients and controls. Conclusion : This study did not prove that the neurological soft signs might be an endophenotype of schizophrenia that cosegregate with the genetic loading. The future study using more subjects than this would be needed.

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Study of Neural Network Training Algorithm Comparison and Prediction of Unsteady Aerodynamic Forces of 2D Airfoil (신경망 학습알고리즘의 비교와 2차원 익형의 비정상 공력하중 예측기법에 관한 연구)

  • Kang, Seung-On;Jun, Sang-Ook;Park, Kyung-Hyun;Jeon, Yong-Hee;Lee, Dong-Ho
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.37 no.5
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    • pp.425-432
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    • 2009
  • In this study, the ability of neural network in modeling and predicting of the unsteady aerodynamic force coefficients of 2D airfoil with the data obtained from Euler CFD code has been confirmed. Neural network models are constructed based on supervised training process using Levenberg-Marquardt algorithm, combining this into genetic algorithm, hybrid genetic algorithm and the efficiency of the two cases are analyzed and compared. It is shown that hybrid-genetic algorithm is more efficient for neural network of complex system and the predicted properties of the unsteady aerodynamic force coefficients of 2D airfoil by the neural network models are confirmed to be similar to that of the numerical results and verified as suitable representing reduced models.

Use of a Genetic Algorithm to Predict the Stiffness Reductions and Retrofitting Effects on Structures Subjected to Seismic Loads (지진하중을 받은 구조물의 유전알고리즘 기반 강성저하 및 보강 효과 추정)

  • Lee, Jae-Hun;Ahn, Kwang-Sik;Lee, Sang-Youl
    • Journal of the Computational Structural Engineering Institute of Korea
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    • v.33 no.3
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    • pp.193-199
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    • 2020
  • This study examines a method for identifying stiffness reductions in structures subjected to seismic loads and retrofitting effects using a combination of the finite element method and an advanced genetic algorithm. The novelty of this study is the application of seismic loading and its response to anomalies in the tested structure. The technique described in this study may enable not only detection of damaged elements but also the identification of their locations and the extent of damage due to seismic loading. To demonstrate the feasibility of the method, the advanced genetic algorithm is applied to frame and truss bridge structures subjected to El Centro and Pohang seismic loads. The results reveal the excellent computational efficiency of the method and its ability to prevent severe damage from earthquakes.

Development of an Expert System for Fatigue Strength Assessment based on Genetic Algorithm (유전적 알고리즘 기반 피로강도평가 전문가시스템개발)

  • 최홍민;서정관;이제명;백점기;강성원;허희영
    • Proceedings of the KWS Conference
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    • 2004.05a
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    • pp.258-260
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    • 2004
  • 현재의 피로강도 평가법에서는 각종 실험적인 방법 및 이론적인 방법 등 여러 가지 방법으로 피로강도설계를 하고 있는 실정이다. 그리고 이러한 피로특성에 대한 정확한 평가를 위해서 대상구조물에 작용하는 하중성분과 재료 및 구조적인 특성의 상호 연관관계에 대한 연구가 지속되어지고 있다. (중략)

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An Analytical Study on System Identification of Steel Beam Structure for Buildings based on Modified Genetic Algorithm (변형 유전 알고리즘을 이용한 건물 철골 보 구조물의 시스템 식별에 관한 해석적 연구)

  • Oh, Byung-Kwan;Choi, Se-Woon;Kim, Yousok;Cho, Tong-Jun;Park, Hyo-Seon
    • Journal of the Computational Structural Engineering Institute of Korea
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    • v.27 no.4
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    • pp.231-238
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    • 2014
  • In the buildings, the systems of structures are influenced by the gravity load changes due to room alteration or construction stage. This paper proposes a system identification method establishing mass as well as stiffness to parameters in model updating process considering mass change in the buildings. In this proposed method, modified genetic algorithm, which is optimization technique, is applied to search those parameters while minimizing the difference of dynamic characteristics between measurement and FE model. To search more global solution, the proposed modified genetic algorithm searches in the wider search space. It is verified that the proposed method identifies the system of structure appropriately through the analytical study on a steel beam structure in the building. The comparison for performance of modified genetic algorithm and existing simple genetic algorithm is carried out. Furthermore, the existing model updating method neglecting mass change is performed to compare with the proposed method.

Decision Support System fur Arrival/Departure of Ships in Port by using Enhanced Genetic Programming (개선된 유전적 프로그래밍 기법을 이용한 선박 입출항 의사결정 지원 시스템)

  • Lee, K. H.;Rhee, W.
    • Proceedings of the Korea Inteligent Information System Society Conference
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    • 2001.06a
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    • pp.383-389
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    • 2001
  • 된 연구에서 대상으로 하고 있는 LG 정유 광양항 제품부두는 7 선석(Berth)에 재화중량(DWT) 300톤에서 48000 톤의 선박까지 다양한 선박이 이용하고 있으며, 해상의 기상상태에 따른 선박 입출향 통제 지침 설정이 어렵고, 현재 사용하고 있는 지침의 근거가 명확하지 않아 현재의 부두 운영이 비효율적이거나 안전성이 결여되어 있다고 할 수 있다. 따라서 이를 개선하기 위한 합리적인 부두운영 제한조건 개발이 절실히 요구되었다. 본 논문에서는 대상 부두의 특성, 대상 선박의 특성, 하중상태, 선박 운항자의 특성 등을 고려하여 해상/기상 상황(바람, 조류 및 파랑)에 따른 부두 입출항 가능 여부를 정량적으로 판단하고, 안전성 향상 방안을 제시할 수 있는 의사결정 시스템을 개발하고 5번, 7번 선석을 대상으로 이를 검증하였다. 여기서는 입출항 여부를 정량적으로 판단하여 결과를 제시하기 위해서 유전적 프로그래밍(Genetic Programming)을 이용한 기계학습 방법을 이용하였으며, GP의 방대한 계산량을 줄이기 위한 가중 선형 연상 기억(Weighted Linear Associative Memory: WLAM) 방법의 도입 및 전역 최적점을 쉽게 찾기 위한 Group of Additive Genetic Programming Trees(GAGPT)를 도입함으로써 학습 성능을 개선하였다.

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A Study on the design Optimization of Thickness of Machiningcenter Bed under Dynamic Loading by using Genetic Algorithm (유전적 알고리듬을 적용하여 머시닝센터 베드두께의 동하중을 고려한 최적설계에 관한 연구)

  • 조백희
    • Journal of the Korean Society of Manufacturing Technology Engineers
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    • v.8 no.1
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    • pp.67-73
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    • 1999
  • This paper presents resizing design optimization method by utilizing genetic algorithm(GA), which consists of three basic operators : reproduction, crossover and mutation. The fitness and penalty function for resizing optimization problem are defined, and the flowchart of the developed computer program along with the descriptions of each modules is presented. Also, modelling for flexible-body dynamic analysis is presented. The model is composed of bodies, joints, and force elements such as translational spring-damper-actuator. The design objects si to determine the wall thickness for minimum weight under dynamic displacement constraint.

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Estimation of the Moving Load Velocity Using Micro Genetic Algorithm (마이크로 유전 알고리즘을 이용한 교통하중의 속도추정)

  • Tak, Moon-Ho;Noh, Myung-Hyun;Park, Tae-Hyo;Park, In-Young
    • Proceedings of the Computational Structural Engineering Institute Conference
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    • 2009.04a
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    • pp.292-295
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    • 2009
  • 본 논문에서는 평판구조물의 정적 및 동적해석에 사용할 목적으로 성능이 향상된 평판유한요소를 제시하였다. 이 요소는 비적합변위형과 선택적 감차적분방법 그리고 대체전단변형률장을 복합적으로 적용하여 각각의 장점들을 포함하는 향상된 거동을 보여주고 있다. 또한 비적합변위형의 적용으로 발생되는 조각시험의 실패 문제점을 해결하기 위하여 직접수정법을 평판유한요소의 개선에 사용하였다. 대표적인 검증문제에 대한 수치해석작업을 통하여 본 연구에서 개발한 요소는 가상적인 제로에너지모드 및 전단잠김현상의 발생과 같은 문제를 나타내지 않음을 알 수 있었다. 특히 찌그러진 형상으로 모형화 한 경우에 있어서도 전단잠김현상이 발생하지 않았다. 본 연구에서 수행한 동적반응해석 시험에 있어서도 이론해와 잘 일치하는 결과를 보여주었다.

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Analysis of Lodging Related Characteristics in Rice Plants (벼 도복에 관여하는 형질 분석)

  • 임준택;이홍재;조광석;송동석
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.37 no.1
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    • pp.78-85
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    • 1992
  • This experiment was carried out to investigate the heritabilities, phenotypic correlation, genetic correlation and path-coefficients for desirable characters on the lodging related traits. Characters, that had high relation degree with field lodging degree, were rice-straw length, Wl /P, W/I, Wl /d, L, Wl / A, W/l, P, W $s^2$/ $l^4$ etc. Breaking strength appear negative correlation having an intention to field lodging. The second inertia moment of culm diameter trunk (branch), cross section area, rice-straw thickness and trunk cross section didn't appear negative coefficient with field lodging. It is considered that rice-straw length, leaf dry weight and lodging index, because of high heritability, become selection index of characters for breeding. In direct, indirect effect, and right rice-straw wall thickness appear largest( $P_{7y}$=0.6904), the next is the order of leaf dry weight( $P_{3y}$=0.2848), root dry weight ( $P_{1y}$=0.2658), culm diameter ( $P_{6y}$=-0.2280), and negative relation appear the order of rice-straw length ( $P_{5y}$=-0.9640) and stem dry weight( $P_{2y}$=-0.7072), therefore, the smaller culm length and stem dry weight, the stronger to lodging. to lodging.

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Optimal Arrangement of Resilient Mount installed on Frame Support Structure at Shipboard Equipment under Shock Load (충격하중하의 탑재장비 프레임 지지구조의 탄성마운트 배치 최적화에 관한 연구)

  • Ji, Yong Jin;Kwak, Jeong Seok;Lee, Hyun Yup;Kim, Sung Chan
    • Journal of the Society of Naval Architects of Korea
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    • v.52 no.4
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    • pp.298-304
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    • 2015
  • Shipboard equipment in naval ships should be designed to be safe under the shock load. Very high stress due to the shock load can be effectively reduced by the resilient mounts considering the mount capacity and dynamic characteristics. An optimum arrangement of resilient mount installed to absorb the shock energy is addressed to assess the safety of ship structure and shipboard equipment subjected to the shock load. Structural responses are analyzed for both frame structure supporting the shipboard equipment subject to the shock load with and without the resilient mounts. The shock absorbability of the resilient mount is evaluated by the results of structural response analysis; meanwhile, several types of shock analyses considering the arrangement of resilient mounts are carried out and the shock responses are compared to verify the effect of the arrangement. Thereafter, optimum arrangements are obtained by means of Genetic algorithm (GA) considering the different capacities of resilient mount. Stress, deformation and dynamic feature at the frame structure supporting the shipboard equipment under the shock load are also discussed in order to meet the capacity of resilient mount.