• 제목/요약/키워드: 유전자 예측

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Numerical Optimization of Foundation place for Domestic Offshore Wind Turbine by using Statistical Models for Wind Data Analysis (기상풍황자료 통계적 분석을 통한 한국형 해상풍력터빈 설치지점 선정 최적화 연구)

  • Lee, Ki-Hak;Jun, Sang-Ook;Ku, Yo-Cheon;Pak, Kyung-Hyun;Lee, Dong-Ho
    • 한국신재생에너지학회:학술대회논문집
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    • 2007.06a
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    • pp.404-408
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    • 2007
  • 현재 국내에서 운용중인 풍력발전시스템은 국내 풍력자원에 대한 정확한 정보의 부재와 국내 풍황에 맞지 않는 국외 모델을 그대로 운용하는 등의 몇 가지 문제를 드러내었다. 본 연구의 목적은 국내 연안의 해상에서 한국형 해상풍력터빈을 설치하기 위한 잠재적 최적위치와 풍황자료 산출 최적화 알고리즘을 구현하는 것이다. 최적화 알고리즘은 얕은 수심 분포와 연안에서의 거리를 제약조건으로 하고 최대 에너지밀도를 가진 지점을 구하는 것으로 정식화하였다. 풍황자료 산출을 위해서 국내 연안의 해상 풍황자료를 포함하는 기상풍황자료를 통계적 모델로 분석하여 바람지도를 작성하였다. 이 바람지도를 이용하여 지질 통계학 분야의 관측기법인 크리깅 모델을 구성하고, 전역최적화기법인 유전자알고리즘을 이용하여 제약조건을 만족하는 최대에너지밀도값과 그 위치를 도출하였다. 수치최적화 결과 우리나라 풍력 자원의 대략적인 잠재량과 현황파악이 가능하였고, 해상풍력발전단지가 조성 가능한 개략적인 위치를 예측할 수 있었다.

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Searching Method for New Small RNA in Bacillus subtilis Using Bioinformation (생물정보를 이용하여 바실러스 서브틸리스에서 새로운 Small RNA를 예측하는 방법)

  • Lee, Sang-Soo
    • The Journal of Natural Sciences
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    • v.18 no.1
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    • pp.47-53
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    • 2007
  • In order to find novel sRNA in Bacillus subtilis which would be used to adapt to several conditions, we searched the whole genome of Bacillus subtilis using the following procedure. At first, the locations of recognition sequence of transcription factors such as PerR, OhrR, Fur and Zur were searched in the intergenic region of Bacillus subtilis genome and the locations of rho independent transcription terminator sites were also determined. Based on the information of these locations, the sRNA candidates were chosen by close locations (less than 300 bp) between the recognition site of transcription factors and rho independent transcription terminator site. Than transcription promoter sites were searched in the region of previously identified sRNA candidates and 5 PerR, 1 OhrR, 1 Fur and 1 Zur regulated good sRNA candidates were found.

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Improving the Accuracy of Early Stage Cost Estimation in Apartment Construction Project (공동주택 프로젝트의 초기 공사비 예측정확도 향상에 관한 연구)

  • Lim, So-Yean;Yeo, Sang-Gu;Go, Seong-Seok
    • Proceedings of the Korean Institute of Building Construction Conference
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    • 2010.05a
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    • pp.143-147
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    • 2010
  • Due to the diversification and complication of construction projects, controlling risks from the early design-planning phase gives huge impact on success of the construction project. As a part of managing uncertainties it is also important to estimate the project cost several times. Especially, estimating project cost in the early stage gives effects on making a budget for projects. This study estimated the apartment project cost using case-based reasoning(CBR), which is the process of solving new problems based on the past problems. For this, we deduced the apartment cost influence factors which can be gathered in the early stage of project. Based on the factors we established the database for apartment project and calculated the attribute value, attribute similarity and case similarity. Although we retrieve the most similar case from the database, it is very hard to utilize it directly due to the uniqueness of each project. So, Genetic Algorithm(GA) was applied in revising the cost of the retrieved-case. Therefore, the accuracy of the prediction was improved by GA optimization.

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Individual Genome Sequences and Their Smart Application In Personalized Medicine (맞춤의학 시대의 개인 유전체 서열의 해독과 스마트한 이용)

  • Kim, Dong Min;Jeong, Haeyoung;Kim, Il Chul;Won, Yonggwan
    • Smart Media Journal
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    • v.2 no.4
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    • pp.34-40
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    • 2013
  • Rapid sequencing of individual genomes with next generation sequencer opens new horizon to biology and personalized medicine. The analyzed sequences help to check several genomic abnormality, genomic expression, epigenomic phenotypes, gene annotation after assembly of their reads. Several trials integrating genomic information and clinical data will assist disease diagnostics and clinical treatments. To have a large step towards individualized medicine, development of smart interface linking specialized sequence data to the public is necessary.

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Gene Sequences Clustering for the Prediction of Functional Domain (기능 도메인 예측을 위한 유전자 서열 클러스터링)

  • Han Sang-Il;Lee Sung-Gun;Hou Bo-Kyeng;Byun Yoon-Sup;Hwang Kyu-Suk
    • Journal of Institute of Control, Robotics and Systems
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    • v.12 no.10
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    • pp.1044-1049
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    • 2006
  • Multiple sequence alignment is a method to compare two or more DNA or protein sequences. Most of multiple sequence alignment tools rely on pairwise alignment and Smith-Waterman algorithm to generate an alignment hierarchy. Therefore, in the existing multiple alignment method as the number of sequences increases, the runtime increases exponentially. In order to remedy this problem, we adopted a parallel processing suffix tree algorithm that is able to search for common subsequences at one time without pairwise alignment. Also, the cross-matching subsequences triggering inexact-matching among the searched common subsequences might be produced. So, the cross-matching masking process was suggested in this paper. To identify the function of the clusters generated by suffix tree clustering, BLAST and CDD (Conserved Domain Database)search were combined with a clustering tool. Our clustering and annotating tool consists of constructing suffix tree, overlapping common subsequences, clustering gene sequences and annotating gene clusters by BLAST and CDD search. The system was successfully evaluated with 36 gene sequences in the pentose phosphate pathway, clustering 10 clusters, finding out representative common subsequences, and finally identifying functional domains by searching CDD database.

An Experimental Study on Mathematical Model to Predict Bead Width in GMA Weldment (GMA 용접부의 비드폭 예측을 위한 수학적 모델에 관한 실험적 연구)

  • Kim, Ill Soo;Park, Min Ho;Kim, Hak Hyoung;Lee, Jong Pyo;Park, Cheol Kyun;Shim, Ji Yeon
    • Journal of the Korean Society for Precision Engineering
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    • v.32 no.2
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    • pp.209-217
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    • 2015
  • Generally welding is one of the most important processes to have a strong influence on the quality and productivity from a manufacture-based industry such as shipbuilding, automotive and machinery. The GMA(Gas Metal Arc) welding process involves large number of interdependent welding parameters which may affect product quality, productivity and cost effectiveness. To solve such problems, mathematical models are required to select the welding parameters for GMA welding process. In this study, the GMA welding process was studied using the information generated during the welding. The statistical analysis of a generalized regression approach was conducted by the following three methods: Firstly using the mathematical model (linear regression, 2nd regression); Secondly GA(Genetic Algorithm) with intelligent models; And finally using response surface analysis of models to develop the relationships between welding parameters and bead width as welding quality.

Estimation of Pollutant Load Using Genetic-algorithm and Regression Model (유전자 알고리즘과 회귀식을 이용한 오염부하량의 예측)

  • Park, Youn Shik
    • Korean Journal of Environmental Agriculture
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    • v.33 no.1
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    • pp.37-43
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    • 2014
  • BACKGROUND: Water quality data are collected less frequently than flow data because of the cost to collect and analyze, while water quality data corresponding to flow data are required to compute pollutant loads or to calibrate other hydrology models. Regression models are applicable to interpolate water quality data corresponding to flow data. METHODS AND RESULTS: A regression model was suggested which is capable to consider flow and time variance, and the regression model coefficients were calibrated using various measured water quality data with genetic-algorithm. Both LOADEST and the regression using genetic-algorithm were evaluated by 19 water quality data sets through calibration and validation. The regression model using genetic-algorithm displayed the similar model behaviors to LOADEST. The load estimates by both LOADEST and the regression model using genetic-algorithm indicated that use of a large proportion of water quality data does not necessarily lead to the load estimates with smaller error to measured load. CONCLUSION: Regression models need to be calibrated and validated before they are used to interpolate pollutant loads, as separating water quality data into two data sets for calibration and validation.

The Applicability Study of SYMHYD and TANK Model Using Different Type of Objective Functions and Optimization Methods (다양한 목적 함수와 최적화 방법을 달리한 SIMHYD와TANK 모형의 적용성 연구)

  • Sung, Yun-Kyung;Kim, Sang-Hyun;Kim, Hyun-Jun;Kim, Nam-Won
    • Journal of Korea Water Resources Association
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    • v.37 no.2
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    • pp.121-131
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    • 2004
  • SIMHYD and TANK model are used to predict time series of daily rainfall-runoff of Soyang Dam and Youngcheon Dam watershed. The performances of SIMHYD model with 7 parameters and TANK model with17 parameters are compared. Three optimization methods (Genetic algorithm, Pattern search multi-start and Shuffled Complex Evolution algorithm) were applied to study-areas with 3 different types of objective functions. Efficiency of TANK model is higher than that of SIMHYD. Among different types of objective function, Nash-sutcliffe coefficient is found to be the most appropriateobjective function to evaluate applicability of model.

Development of Clustering Algorithm based on Massive Network Compression (대용량 네트워크 압축 기반 클러스터링 알고리즘 개발)

  • Seo, Dongmin;Yu, Seok Jong;Lee, Min-Ho
    • Proceedings of the Korea Contents Association Conference
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    • 2016.05a
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    • pp.53-54
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    • 2016
  • 빅데이터란 대용량 데이터 활용 및 분석을 통해 가치 있는 정보를 추출하고, 이를 바탕으로 대응 방안 도출 또는 변화를 예측하는 기술을 의미한다. 그리고 빅데이터 분석에 활용되는 데이터인 페이스북과 같은 소셜 데이터, 유전자 발현과 같은 바이오 데이터, 항공망과 같은 지리정보 데이터들은 대용량 네트워크로 구성되어 있다. 네트워크 클러스터링은 서로 유사한 특성을 갖는 네트워크 내의 데이터들을 동일한 클러스터로 묶는 기법으로 네트워크 데이터를 분석하고 그 특성을 파악하는데 폭넓게 사용된다. 최근 빅데이터가 다양한 분야에서 활용되면서 방대한 양의 네트워크 데이터가 생성되고 있고, 이에 따라서 대용량 네트워크 데이터를 효율적으로 처리하는 클러스터링 기법의 중요성이 증가하고 있다. MCL(Markov Clustering) 알고리즘은 플로우 기반 무감독(unsupervised) 클러스터링 알고리즘으로 확장성이 우수해 다양한 분야에서 활용되고 있다. 하지만, MCL은 대용량 네트워크에 대해서는 많은 클러스터링 연산을 요구하며 너무 많은 클러스터를 생성하는 문제를 갖는다. 본 논문에서는 네트워크 압축을 기반으로 한 클러스터링 알고리즘을 제안함으로써 MCL보다 클러스터링 속도와 정확도를 향상시켰다. 또한, 희소행렬을 효율적으로 저장하는 CSC(Compressed Sparse Column) 자료구조와 MapReduce 기법을 제안한 클러스터링 알고리즘에 적용함으로써 대용량 네트워크에 대한 클러스터링 속도를 향상시켰다.

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A Study of Progressive Parameter Calibrations for Rainfall-Runoff Models (강우-유출모형을 위한 매개변수 순차 보정기법 연구)

  • Kwak, Jae-Won;Kim, Duk-Gil;Hong, Il-Pyo;Kim, Hung-Soo
    • Journal of Wetlands Research
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    • v.11 no.2
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    • pp.107-121
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    • 2009
  • Many rainfall-runoff models have been used for the flood forecasting. However, the determination of rainfall-runoff model parameters is very difficult. In this study, we investigated the efficiency of flood forecasting models by studying the optimization techniques for parameter calibration of SFM, Tank, and SSARR models. We analyzed the correlations between parameters in optimization techniques, then classified the parameters into parameter groups. For this we applied the sequential calibration method through the sensitivity analysis. As the results of the analysis, the parameter groups clibration method showed better result for peak flow and clibtation time.

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