• Journal of Chest Surgery
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• v.37 no.1
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• pp.1-10
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• 2004

Background: Currently, the cardiopulmonary machine with non-pulsatile pumps, which are low in internal circuit pressure and cause little damage to blood cells, is widely used. However, a great number of experimental studies shows that pulsatile perfusions are more useful than non-pulsatile counterparts in many areas, such as homodynamic, metabolism, organ functions, and micro-circulation. Yet, many concerns relating to pulsatile cardiopulmonary machines, such as high internal circuit pressure and blood cell damage, have long hindered the development of pulsatile cardiopulmonary machines. Against this backdrop, this study focuses on the safety and effectiveness of the pulsatile cardiopulmonary machines developed by a domestic research lab. Material and Method: The dual-pulsatile cardiopulmonary bypass experiment with total extracorporeal circulation was conducted on six calves, Extracorporeal circulation was provided between superior/inferior vena cava and aorta. The membrane oxygenator, which was placed between the left and right pumps, was used for blood oxygenation. Circulation took four hours. Arterial blood gas analysis and blood tests were also conducted. Plasma hemoglobin levels were calculated, while pulse pressure and internal circuit pressure were carefully observed. Measurement was taken five times; once before the operation of the cardiopulmonary bypass, and after its operation it was taken every hour for four hours. Result: Through the arterial blood gas analysis, PCO2 and pH remained within normal levels. PO2 in arterial blood showed enough oxygenation of over 100 mmHg. The level of plasma hemoglobin, which had total cardiopulmonary circulation, steadily increased to 15.87 $\pm$ 5.63 after four hours passed, but remained below 20 mg/㎗. There was no obvious abnormal findings in blood test. Systolic blood pressure which was at 97.5$\pm$5.7 mmHg during the pre-circulation contraction period, was maintained over 100 mmHg as time passed. Moreover, diastolic blood pressure was 72.2 $\pm$ 7.7 mmHg during the expansion period and well kept at the appropriate level with time passing by. Average blood pressure which was 83$\pm$9.2 mmHg before circulation, increased as time passed, while pump flow was maintained over 3.3 L/min. Blood pressure fluctuation during total extracorporeal circulation showed a similar level of arterial blood pressure of pre-circulation heart. Conclusion: In the experiment mentioned above, pulsatile cardiopulmonary machines using the doual-pulsatile structure provided effective pulsatile blood flow with little damage in blood cells, showing excellence in the aspects of hematology and hemodynamic. Therefore, it is expected that the pulsatile cardiopulmonary machine, if it becomes a standard cardiopulmonary machine in all heart operations, will provide stable blood flow to end-organs.

• Journal of Environmental Impact Assessment
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• v.32 no.6
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• pp.437-449
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• 2023

This study measured PM₁₀ concentrations and wind speeds in buffer green spaces and neighborhood parks located along the road, and compared them with roadside measurementresults to understand the effect of mitigating PM₁₀ concentrations by type of green space and the influence of wind speeds on it. As a result of the analysis, the effect of mitigating PM₁₀ concentration was different depending on the type of roadside green space, and an increase in wind speed had a significant effect on reducing PM₁₀ concentration. In buffer green areas with high planting density, wind speed was low and PM₁₀ stagnated inside, resulting in the highest concentration. On the other hand, green areas in neighborhood parks with relatively low planting density had high wind speeds and the lowest PM₁₀ concentration. The non-green area within the neighborhood park recorded the highest wind speed, which was advantageous for the spread of PM₁₀, but the concentration was higherthan that of the green area. Therefore, in orderto reduce PM₁₀ concentration in roadside green space, it is necessary to create green space with good ventilation, and the combined effect of green space and wind speed seems to be more advantageous in reducing PM₁₀ concentration. Green spaces capture and remove PM inside, contributing to reducing the concentration of PM outside. In order to manage PM in the entire city and on roads, it is necessary to increase planting density and leaf area in roadside green spaces, such as buffer green spaces, so that PM can be removed within the green spaces. However, in green spaces such as neighborhood parks that are actively used by city residents, in orderto minimize damage to users due to PM, it is desirable to create green spaces with a structure that allows PM to spread to the outside rather than stagnate inside.

• Analytical Science and Technology
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• v.32 no.6
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• pp.243-251
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• 2019

Microplastics (MP) are found in large quantities in the oceans, posing a major threat to the ecosystem. In Korea, MPs have been reported to be detected in sea salts. In order to analyze MPs, information on their composition, size, and shape is required. FT-IR microscopy is used frequently to measure sizes larger than 20 ㎛. Recently, however, Raman microscopy, which can analyze ultrafine plastics below 20 ㎛, has been applied extensively. In this study, 10.0 g samples of commercially available salts were dissolved and filtered through a 45 ㎛ mesh filter with a size of 25.4 mm × 25.4 mm. These filtered samples were then analyzed by both FT-IR microscopy and Raman microscopy. A total of four MPs, including three polyethylene (PE) of size 70-100 ㎛ and a polypropylene (PP) of size 170 ㎛, were detected by FT-IR microscopy, while 10 MPs, including nine PE of size 10-120 ㎛ and one polystyrene (PS) of size 40 ㎛, were detected by Raman microscopy. Approximately, 1,000 MPs/kg was estimated, which was almost two times higher than the previous reported levels (~550-681 particles/kg in sea salts); this is because Raman microscopy can detect much smaller MPs than FT-IR microscopy. A total of 113 particles were found using Raman microscopy: Carbon (35, 31.5 %), minerals (28, 25 %), and glass (16, 14.4 %) were dominant, forming around 70% of the total, but MPs (10, 8.8 %) and cellulose (5, 4.5 %) were also found. Raman microscopy has great potential as an accurate method for measuring MPs, as it can measure smaller size MPs than FT-IR microscopy. It also has a reduced sample preparation time.

• Horticultural Science & Technology
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• v.33 no.2
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• pp.268-275
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• 2015

We evaluated the effect of mixed liquid fertilizer (MLF) on growth responses of plants and soil chemical properties. To do so, a pot experiment with cherry tomatoes (Lycopersicon esculentum var. cerasiforme) using loam soil was conducted for 81 days in a temperature-controlled glasshouse, and four N fertilization treatments were laid out in a completely randomized design with three replicates: control (C), chemical fertilizer treatment (CF), and two rates (MLF-0.5 and MLF-1.0) of MLF treatment. Soils were periodically sampled and analyzed for pH, EC, total N, inorganic N and total C, and growth characteristics of cherry tomatoes were measured. During the experimental periods, the pH of MLF soils was higher than that of CF soils. Soil total-N content increased right after CF-application and ultimately decreased to the level of the control (C) soil, while MLF-application slightly increased the level of soil total-N and this level remained unchanged throughout the experiment. The levels of soil inorganic N content increased after application of CF or MLF, but the initial increase disappeared in 56 days after transplanting (DAT). The dry weight of shoots and roots increased in CF or MLF plants, while the number of fruit increased only in MLF plants. Whereas soluble solid contents were higher in MLF plants than in the other (C and CF) plants, the titratable acidity was not different among treatments. However, no consistent effect of N treatments on major elements of the organs of cherry tomatoes was found. The amounts of N taken up by plants were 0.91 g for CF, 0.61 g for MLF-1.0, 0.43 g for MLF-0.5, and 0.25 g for control treatments, resulting in greater N efficiency for CF than for MLF.

• Economic and Environmental Geology
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• v.50 no.2
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• pp.171-180
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• 2017

This study performed the analysis on the volcanic gases and hot spring waters from the Julong hot spring at Mt. Baekdu during the period from July 2015 to August 2016. Also, we confirmed the errors that $HCO_3{^-}$ concentrations of hot spring waters in the previous study (Lee et al. 2014) and tried to improve the problem. Dissolved $CO_2$ in hot spring waters was analyzed using gas chromatograph in Lee et al. (2014). Improving this, from 2015, we used TOC-IC to analysis dissolved $CO_2$. Also, we analyzed the $Na_2CO_3$ standard solutions of different concentrations using GC, and confirmed the correlation between the analytical concentrations and the real concentrations. However, because the analytical results of Julong hot spring water were in discord with the estimated values based on this correlation, we can't estimate the $HCO_3{^-}$ concentrations of 2014 samples. During the period of study, $CO_2/CH_4$ in volcanic gases are gradually decreased, and this can be interpreted in two different ways. The first interpretation is that the conditions inside the volcanic edifice are changing into more reduction conditions, and carbon in volcanic gases become more favorable to distribute into $CH_4$ or CO than $CO_2$. The second interpretation is that the interaction between volcanic gases and water becomes greater than past, and the concentrations of $CO_2$ which have much higher solubility in water decreased, relatively. In general, the effect of scrubbing of volcanic gas is strengthened during the quiet periods of volcanic activity rather than active periods. Meanwhile, the analysis of hot spring waters was done on the anion of acidic gases species, the major cation, and some trace elements (As, Cd, Re).

• Journal of Korean Society of Environmental Engineers
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• v.30 no.9
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• pp.961-972
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• 2008

In 2004, total emissions of Greenhouse Gases(GHGs) in Korea was estimated to be about 590 million metric tons, which is the world's 10th largest emissions. Considering the much amount of nation's GHG emissions and growing nation's position in the world, GHG emissions in Korea should be reduced in near future. The CO$_2$ emissions from two sub-sections of energy sector in Korea, such as thermal power plant and industry section(including manufacturing and construction industries), was about 300 million metric tons in 2004 and this is 53.3% of total GHG emissions in Korea. So, the mitigation of CO$_2$ emissions in these two section is more important and more effective to reduce the nation's total GHGs than any other fields. In addition, these two section have high potential to qualitatively and effectively apply the CCS(Carbon Capture and Storage) technologies due to the nature of their process. There are several CCS technologies applied to these two section. In short term, the chemical absorption technology using amine as a absorbent could be the most effectively used. In middle or long term, pre-combustion technology equipped with ATR(Autothermal reforming), or MSR-$H_2$(Methane steam reformer with hydrogen separation membrane reactor) unit and oxyfuel combustion such as SOFC+GT(Solid oxide fuel cell-Gas turbine) process would be the promising technologies to reduce the CO$_2$ emissions in two areas. It is expected that these advanced CCS technologies can reduce the CO$_2$ avoidance cost to $US 8.5-43.5/tCO$_2$. Using the CCS technologies, if the CO$_2$ emissions from two sub-sections of energy sector could be reduced to even 10% of total emissions, the amount of 30 million metric tons of CO$_2$ could be mitigated.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.26 no.4
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• pp.380-391
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• 1993

The experimental study was made to propose the treatment method of wastewater in the high-density fish culture system. The BOD to COD ratios of effluents were almost same to 0.65 in the eel-farm, but were various in the farm rearing together with tilapia etc. A BOD rate curve of the eel-farm effluent could be described mathematically by the equation, $BODu=14.1(1-10^{-0.222t})+30.9(1-10^{-0.035(t-8)})$. Nitrification in Biological Fluidized Bed(BFB) system to treat the fish-farm wastewater could be reduce ammonium level up to $65{\sim}79\%$ when ammonium loading rates were between 0.014 and 0.075g $NH_4/g$ BVS-day. Nitrification efficiency was decreased by organic matters in the wastewater when ammonium loading was low(0.014 g $NH_4/g$ BVS-day). T-N removal ratios were decreased to increase loading in denitrification process, because of low C/N ratio. Based on much higher biological mass concentrations, BFB system takes many advantages of a practical viewpoint, such as stability of treatment efficiency and reduction of necessary site area for the facility, as compared with conventional treatment systems.

• Journal of the korean academy of Pediatric Dentistry
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• v.28 no.3
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• pp.441-446
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• 2001

Flumazenil is a competitive antagonist of benzodiazepines. It is usually administered intravenously. However, if the intravenous route is not available then other routes of drug administration should be considered. This study was designed to evaluate the reversal effects of flumazenil after nasal administration. Twenty-five young, healthy adult volunteers participated in this clinical trial. The dosage of 0.08mg/kg midazolam was administered intravenously to induce deep sedation. Ten minutes after midazolam administration, 0.5mg of flumazenil was dropped nasally, over a period of one minute. Blood samples were taken to measure the concentration of midazolam and flumazenil at 0, 5, 10, and 20min after nasal administration of flumazenil, using High Performance Liquid Chromatography. The degree of sedation was evaluated with sedation score and bispectral index (BIS), Statistical analysis was performed by multivariate ANOVA and correlation analysis (P<0.05). Peak serum flumazenil concentration was reached in 10min. Sedation score decreased after midazolam administration and showed a significant increase after flumazenil administration. However, BIS decreased during the first 10min after midazolam administration and then no significant changes after flumazenil administration. There were two instances representing rapid and complete reversal of midazolam after intranasal administration of flumazenil. In conclusion, intranasal flumazenil administration may be effective in some patients when intravenous route is not available in condition of benzodiazepine overdose.

• Journal of Bio-Environment Control
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• v.13 no.1
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• pp.51-55
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• 2004

The most commonly used inorganic nutrient compositions such as Murashige & Skoog medium have been optimized for heterotrophic growth. Therefore, they may not be optimal for photomixotrophic and photoautotrophic growth of plantlets. In photomixotrophic micropropagation, emdium sugar level is often lowered, while light and $CO_2$ levels in vessel are raised, and chlorophyllous explants are used to facilitate photosynthetic carbon acquisition. In a factorial experiment effect of addition (+) and omission(_) of organic materials (OM, 0.5 g ${\cdot}$ $m^{-3}$ each of thiamine, nicotinic acid and pyridoxine and 100 ${\cdot}$ $m^{-3}$ myo-inositiol) combined with three sucrose levels (0, 15, and 30 kg ${\cdot}$ $m^{-3}$) was tested on the growth of potato plantlets. Each of nodal cuttings with a leaf was cultured on 0.1${\times}$$10^{-4}m^{-3}$) MS agar ( 8 kg ${\cdot}$ $m^{-3}$) medium (pH 5.80 before autoclave) in glass test tubes (100 mm${\times}$25mm) capped with a sheet of transparent film with a 6 mm diameter gas permeable filter (5.1 air exchanges ${\cdot}$$h^{-1}$). Cultures were maintained in a room for 27 days at $23^{\circ}C$, 50% RH, 350-450${\mu}mol\;{\codt}\;mol^{-1}CO_2$, 16 h ${\cdot}$ $d^{-1}$ photoperiod at 13${\mu}mol\;{\codt}\;m\;{\codt}\;s^{-1}$ PPFD provided by white cool fluorescent lamps. Growth of potato plantlet in the +OM and -OM treatments were similar, while medium pH was 0.2 scale lower in the latter. Dry weight, % dry matter, and stem diameter enhanced, while shoot to root dry weight ratio, leaf area, chlorophyll concentration per gram dry weight, and medium pH decreased with increasing initial sucrose level. Interaction between OM and sucrose levels was observed in shoot length and medium pH. Results indicate that OM can be omitted from the medium without detrimental effect while addition of sucrose was beneficial for the photomixotrophic growth of potato plantlets under raised light and $CO_2$.

• Korean Chemical Engineering Research
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• v.60 no.4
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• pp.606-612
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• 2022

Relatively high indoor CO₂ concentration (>1,000 ppm) has a negative impact on human health. In this work, indoor CO₂ adsorbent was developed by impregnating KOH or K₂CO₃ on commercial activated carbon, named as KOH/AC and K₂CO₃/AC. Commercial activated carbon (AC) showed relatively high BET surface area (929 m²/g) whereas KOH/AC and K₂CO₃/AC presented lower BET surface area of 13.6 m²/g and 289 m²/g. Two experimental methods of TGA (2,000 ppmCO₂, weight basis) and chamber test (initial concentration: 2,000 ppmCO₂, CO₂ IR analyzer) were used to investigate the adsorption capacity. KOH/AC and K₂CO₃/AC exhibited similar adsorption capacities (145~150 mg_CO2/g), higher than K₂CO₃/Al+Si supports adsorbent (84.1 mg_CO2/g_sample). Similarly, chamber test also showed similar trend. Both KOH/AC and K₂CO₃/AC represented higher adsorption capacities (KOH/AC: 93.5 mg_CO2/g K₂CO₃/AC: 94.5 mg_CO2/g_sample) K₂CO₃/Al+Si supports. This is due to the KOH or K₂CO₃ impregnation increased alkaline active sites (chemical adsorption), which is beneficial for CO₂ adsorption. In addition, the regeneration test results showed both K-based adsorbents pose a good regeneration and reusability. Finally, the current study suggested that both KOH/AC and K₂CO₃/AC have a great potential to be used as CO₂ adsorbent for indoor CO₂ adsorption.