• Title/Summary/Keyword: 유리병

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Diabetic Nephropathy in Childhood and Adolescence (II) ; Pathology and Pathophysiology (소아청소년기 당뇨병성 신병증 (II) ; 병리 소견 및 병태생리를 중심으로)

  • Ha, Tae-Sun
    • Childhood Kidney Diseases
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    • v.13 no.2
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    • pp.99-117
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    • 2009
  • Diabetic nephropathy is a major cause of chronic renal failure in developing countries, and the prevalence rate has markedly increased during the past decade. Diabetic nephropathy shows various specific histological changes not only in the glomeruli but also in the tubulointerstitial region. In the early stage, the effacement of podocyte foot processes and thickened glomerular basement membrane (GBM) is noticed even at the stage of microalbuminuria. Nodular, diffuse, and exudative lesions, so-called diabetic glomerulosclerosis, are well known as glomerular lesions. Interstitial lesions also exhibit fibrosis, edema, and thickened tubular basement membrane. Diabetic nephropathy is considered to be multifactorial in origin with increasing evidence that one of the major pathways involved in the development and progression of diabetic nephropathy as a result of hyperglycemia. Hyperglycemia induces renal damage directly or through hemodynamic alterations, such as, glomerular hyperfiltration, shear stress, and microalbuminuria. Chronic hyperglycemia also induces nonhemodynamic dysregulations, such as, increased production of advanced glycosylation endproducts, oxidative stress, activation of signal pathway, and subsequent various cytokines. Those pathogenic mechanisms resulted in extracellular matrix deposition including mesangial expansion and GBM thickening, glomerular hypertrophy, inflammation, and proteinuria. In this review, recent opinions on the histopathologic changes and pathophysiologic mechanisms leading to initiation and progression of diabetic nephropathy will be introduced.

Isozymic Characteristics of Multiple-Ear and Tiller Maize Lines (다수다얼성 옥수수의 동위효소 특성)

  • ;Bong-Ho Chae
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.32 no.1
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    • pp.16-23
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    • 1987
  • This experiment was conducted to determine the isozymic differences between normal maize and maize inbreds of multiple ears and tillers (MET). Two maize inbreds Euisung, Iri and their hybrid having tillers and multiple ears were compared with normal maize. With usual electrophoresis using 6% polyacrylamide gel, peroxidase and esterase enzymes were studied. Matured leaf, culm, leaf sheath, root and young ear tissues showed different isozymic patterns between METs and normal maize in peroxidase. The Euisung inbred grown for 7 days under dark condition showed typical peroxidase. bands compared with checks in the tissues of coleoptile and stele. Better observation of isozymic bands was made during early part of maize growth. Parental inbreds showed more active and apparent band differences than their hybrids in esterase. Bands for esterase were also apparently different in the stele, coleoptile and young ear tissues of the METs and the checks. The maize lines infected with black streaked dwarf virus showed obvious differences in peroxidase and esterase isozymes.

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Conservation of a Bronze Incense Burner from Chungung-dong, Hanam (하남시 춘궁동 출토 청동현향로(靑銅懸香爐)의 제작기술과 보존처리)

  • Jeong, Subin;Park, Haksoo
    • Conservation Science in Museum
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    • v.16
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    • pp.32-45
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    • 2015
  • The bronze incense burner, discovered in Chungung-dong, Hanam, Gyeonggi-do in 1971, is a hanging incense burner dating from the Goryeo period. The incense burner was covered with a thick layer of clay. The object was in a severely deteriorated state, affected by bronze disease which resulted in extensive corrosion. Numerous cracks were present across its surface, and some parts had been broken off. To preserve and display the bronze incense burner in a stable condition, deposits of foreign material were removed from the surface, and the weakened metal was strengthened. Cracked and broken areas were reinforced using woven glass fiber, followed by the application of epoxy resin to restore the shape. To investigate the method of production, a chemical analysis was performed, and the microstructure was examined. The chemical analysis revealed that the body of the incense burner as well as the ear, loop, lid and the knob were cast in a ternary alloy of Cu-Sn-Pb. Moreover, copper nails with high copper content were used to securely join the ear to the body of the incense burner. The microstructure was mainly α-phase, and non-intermetallic inclusions composed of Cu and S were detected.

Comparison Polyclonal IgGs Labeled with $^{123}I,\;^{99m}Tc,\;^{111}In$ and $^{111}In$ Oxine Leukocytes in the Staphylococcal Abscess Bearing Rats ($^{123}I,\;^{99m}Tc,\;^{111}In$ 표지 사람비특이 항체와 $^{111}In$ Oxine 표지 백혈구의 포도상구균 농양유발 백서에서의 동태비교)

  • Lim, Sang-Moo;Chun, Kwon-Soo;Woo, Kwang-Sun;Chung, Wee-Sup;Lee, Jong-Du
    • The Korean Journal of Nuclear Medicine
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    • v.29 no.1
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    • pp.92-97
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    • 1995
  • 감염병소와 진단을 위해 여러 방사성성핵종 표지 사람비특이항체들이 임상이용되었으나, $^{123}I,\;^{99m}Tc,\;^{111}In$등 표지 핵종과 표지방법에 따른 체내동태의 차이에 대한 자료가 필요하며, 감염병소의 진단에 표준적으로 이용되어지던 $^{111}In$-oxine표지백혈구와 비교평가도 요구된다. 저자들은 $10^9$개의 포도상구균을 좌측 대퇴부에 주사하여 농양을 유발한 백서에서 $^{123}In$ 표지, iminothiolane을 이용한 $^{99m}Tc$ 표지, DTPA이용 $^{111}In$ 표지 사람비특이항체와 $^{111}In$-oxine 표지 백혈구의 체내동태 및 농양섭취율을 비교하였다. $^{123}In$-IgG는 갑상선 및 위의 방사능이 높아 체내 탈요드반응이 빠름이 시사되었으며, $^{99m}Tc$-iminothiolane IgG는 신장방사능이 높아 신장으로 IgG 또는 대사물이 배설됨을 알 수 있었다. $^{111}In$-oxine표지 백혈구는 간 및 비장의 방사능이 높았고, 혈액방사능 제거율이 가장 빨랐다. 주사 24시간 후의 농양섭취율은 $^{111}In$-DTPA IgG가 가장 높았고, 농양 대 혈액 방사능비는 $^{111}In$-oxine표지 백혈구가 가장 높았으며, $^{111}In$-DTPA IgG와 $^{99m}Tc$-iminothiolane IgG가 다음으로 비슷하였다. $^{111}In$-oxine표지 백혈구보다는 방사성핵종표지 IgG가 간편하게 이용될 수 있으며, $^{111}In$$^{99m}Tc$$^{123}In$보다 지연영상의 촬영에 유리함을 알 수 있었다.

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사상체질(四象體質)과 비만(肥滿)의 상관성에 관한 임상적 연구

  • Kim, Dal-Rae;Baek, Tae-Hyeon
    • Journal of Sasang Constitutional Medicine
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    • v.8 no.1
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    • pp.319-335
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    • 1996
  • 연구 목적 : 복지부 발표 '1993년도 대한민국 국민들의 영양상태'보고서를 보면 1인당 섭취열량은 1969보다 257Kcal가 줄어든 것으로 나타났다. 그런데도 불구하고 일부의 사람들은 과도한 열량을 섭취하고 있기 때문에 비만인 사람이 점점 늘어나고 있다. 그렇다보니 신문이나 잡지에서는 거의 매일 살빼는 약이나 신종 다이어트방법에 대한 광고와 기사를 앞다투어 내보내고 있는 실정이다. 비만증은 근래에 발병률이 현저히 증가하면서 중풍, 당뇨병, 고혈압, 암, 간경화증, 당석증 등의 만성질환의 이환율을 증가시키고, 관절에 큰 부담을 주어 골관절염을 보다 빠르게 진전시키며, 사람들의 수명을 단축시키는 등 심각한 건강상의 문제를 일으키고 있다. 또한 비만증은 용모의 손상을 일으켜 정신적인 스트레스의 주요 인자로 등장하고 있기도 하다. 비만인이 증가하는 원인으로는 서구화된 음식습관으로 동물성 지방질과 단백질의 섭취증가, TV 자동차 세탁기 오디오 리모콘 등 생활이기의 사용으로 인한 운동부족, 체질과 질병 등이 재기되고 있다. 이제까지 비만을 치료하기 위한 많은 시도가 있었으나 주된 이론은 섭취음식의 절재와 운동량을 증가시키는 것이었으며, 체질적인 요소를 중심으로 비만증을 해결하려는 시도는 없었다. 이에 저자는 1992년 8월 20일부터 1995년 8월 19일까지 만 3년동안 상지대학교 부속한방병원 체질의학과에서 치료받는 461명의 환자를 대상으로 사상체질과 비만과의 상관성을 임상적으로 연구하고 그 효과를 보고하는 바이다. 연구 결론 : 상지대학교 부속한방병원에 내원치료를 받고 있는 비만증환자들을 대상으로하여 체질과 비만과의 관계를 연구한 결과는 다음과 같다. 1. 비만증 환자의 70.2%가 태음인이었다. 2. 치료결과 4주동안에는 $1.48{\pm}1.64kg$, 5주부터 8주동안에는 $2.05{\pm}2.10kg$, 9주부터 12주동안에는 $2.18{\pm}2.27kg$, 13주부터 16주동안에는 $2.08{\pm}2.88kg$이 감량되었다. 3. 체중감량에 있어 태음인이 가장 많은 감소를 보였다. 연령별로는 10대에서 가장 많은 감소를 보였다. 4. 비만환자의 혈액 가운데 총 콜레스테롤, 저밀도 지방단백이 높온 사람보다 유리지방산과 중성지방이 높은 경우가 대부분을 차지했다. 5. 비만인의 혈청지질에서는 FFA, TG가 높았다. 그 이유는 육식보다는 당질과 지방질의 섭취로 나타난 것이었다.

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Primary Hepatic Lymphoma: MR Imaging and Pathologic Correlation (일차성 간림프종: 자기공명영상과 병리소견의 연관)

  • Kim, Han-Na;Shin, Yu-Ri;Rha, Sung-Eun;Jung, Eun-Sun;Oh, Soon-Nam;Choi, Joon-Il;Jung, Seung-Eun;Lee, Young-Joon
    • Investigative Magnetic Resonance Imaging
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    • v.14 no.2
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    • pp.151-155
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    • 2010
  • Primary hepatic lymphoma is extremely rare, representing less than 1% of all extranodal lymphomas. We report MR imaging features and pathologic correlation of a case of primary hepatic lymphoma. MR images showed a large lobulated mass with gradual contrast enhancement, resembling intrahepatic cholangiocarcinoma. However, both hepatobiliary phase image obtained 20 minutes after injection of hepatocyte specific contrast agent and diffusion-weighted image demonstrated characteristic three layered pattern representing viable lymphoma in the outer layer, tumor necrosis in the middle layer and necrotic hepatic parenchyma in the center.

An Analysis of Consumers Preferences and Price Sensitivity when Purchasing Domestic Wine (국내산 포도주에 대한 소비자 선호 및 가격 민감성 분석)

  • Son, Mi-Yeon;Ryu, Jin-Chun;Kim, Tea-Kyun
    • Food Science and Preservation
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    • v.16 no.1
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    • pp.17-22
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    • 2009
  • This study analyzes consumers preferences and price sensitivity when buying domestic wine. Data were collected from the consumers (n=200) living in Daegu, Korea. Statistical analyses evaluated purchase, frequency, perceptual mapping, and price sensitivity measurement (PSMs) using SPSS software. Among three domestic wines, ice wine (Vin Coree) attracted most customer satisfaction. The second most popular wine was a white wine (Vin Coree) and the third was a red wine (Royal Campbell). The colors of the red and white wines were highly valued, and bottle design was reported to be the best feature of ice wine. Red wine needs to increase in price and to improve in quality because the price is lower than the point of marginal cheapness. White wine should be reduced in price because the price is higher than the optimal pricing point. The price of ice wine is equal to the point of marginal expensiveness; Thus, the price of ice wine should be reduced.

Effects of Planting Time and Mulching Materials on Growth Characteristics and Yield in Cassia tora L. (결명(決明)의 파종기(播種期)와 피복재료(被覆材料)가 생육(生育) 및 수량(收量)에 미치는 영향(影響))

  • Lee, He-Duck;Kim, Chang-Yeong;Rho, Tae-Hong;Lee, Jong-Chul
    • Korean Journal of Medicinal Crop Science
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    • v.1 no.2
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    • pp.158-161
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    • 1993
  • This experiments were carried out determine planting date for highest Yields and select an covering material for enhancement of environments in Cassia tora L.The highest Yields by regressions estimate produced 352 kg/10a at May 18. of coure, it is possible to plant at June and early-July in spite of slight decreas of Yields, therefore Cassia tora L. is benefit to establish cropping system with barley, wheat or other crops. The covering materials for highest yielding was Black-white nonporous PE(low density) and it out yielded about 53% than conventional cultivations. Cassia tora L. is possible to produce Without agricultural medicines because of little occurence of decrease except occuring of Damping off(Rhizoctonia solanikuhn) at early planting.

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Electron Microscopic Observations on the tissues infected with Nuclear Polyhedosis Virus of Bombyx mori during eary stage (가잠 핵다각체병 바이러스 초기감염에 관한 전자현미경적 관찰)

  • 유강선;강석권
    • Journal of Sericultural and Entomological Science
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    • v.32 no.1
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    • pp.49-57
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    • 1990
  • To investigate the pathway of Nuclear Polyhedrosis Virus(NPV) of Bombyx mori in early stage infection of 2nd instar larva, the larval tissues were observed under electron microscope at interval of 6, 12, 24, and 48 hours after virus inoculation. The results are as follows. 1. The intact and enveloped nucleocapsids released from the polyhedra protein in the gut lumen apparently entered with the microvilli. 2. Virus progenies were observed in columnar cell nuclei 24 hours after inoculation, but polyhedra was not seen. The enveloped virus was observed in some of the intercellular spaces between mid-gut cells. 3. Many enveloped virus particles appeared in the basement membrane. These enveloped virus particles passed the basement membrane and gathered at blood cells in heomocoeal. 4. The NPV muliplicates in nuclei of the blood cells and the tracheal cells normally.

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Textbook Analysis of Middle School-Home Economics and Survey on Consumption Status and Nutritional Knowledge of Milk and Dairy Products of Middle School Students in Gongju City, Chungnam Province (중학교 가정교과서의 우유 교육 내용 분석과 중학생의 우유·유제품 섭취 실태 및 영양지식 조사 - 충남 공주시 중학생을 중심으로 -)

  • Kim, Sun Hyo
    • Journal of Korean Home Economics Education Association
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    • v.29 no.4
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    • pp.117-131
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    • 2017
  • This study was performed to analyze education contents related to milk in current home economics textbooks of middle school, and to investigate intake status, consumption behaviors, perception and nutritional knowledge of milk and dairy products among 364 middle school students in Gongju for improvement of milk education in home economics subjects and milk intake of adolescents. As a result, education contents of milk and dairy products in home economics textbooks currently applied in middle school were major nutrients, consumption method for balanced diet, and selection and storage of milk and dairy products, thus it tended not to match current food trend. Only 30.5% of subjects met 2 cups of milk a day, the recommended level. The main reason for drinking milk was to 'be taller' and 'to quench thirst' and there was a difference by gender(p<0.01). The rate of not participating in school milk program was 23.1% of total and its satisfaction was moderate. The most popular dairy products by subjects were ice cream, followed by yogurt and cheese, and the choice of milk was focused on 'taste' or 'expiration date'. The rate of knowing certification mark of K-MILK was low at 28.8%, and most subjects knew as 'domestic milk use'. In home economics class, experience-based learning such as cow ranch experience was the most preferred instruction method for milk followed by laboratory practice and lecture, and there was a difference by gender(p<0.001). Perception degree of milk and dairy products was moderate and male subjects were more positively perceived than female subjects(p<0.01). Nutritional knowledge level of milk and dairy products was moderate and female subjects were higher than male subjects(p<0.01). Therefore, education contents of milk and dairy products of home economics textbooks of middle school should be centered on real life in accordance with food trend, and applied student participation-based instruction methods such as experience-based learning. In addition, it is necessary to enhance taste and merchandise of milk and to provide them with preferred milk and dairy products in school milk program for improvement of milk intake of adolescents.