• Korean Journal of Microbiology
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• v.38 no.3
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• pp.205-212
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• 2002

This study was conducted to develop a method for direct determination of phagocytic activities in human circulatic systems and to measure the phagocytic activities in human leukocytes from the alcoholics, since phagocytic activity was considered to be very important in human immune mechanism at early stage for the health care of the alcoholics. The subjects for this study were 130 among which 95 males and 3 females were diagnosed as alcoholism and 32 was healthy blood donors. A thin layer of heat-killed Staphylococcus aureus Cowan I was placed on a plastic dish and reacted with whole blood to measure the phagocytic plaque formation by human leukocytes. In order to determine the health conditions of the subjects, some clinical laboratory tests, such as white blood cell counts, hemoglobin contents (Hgb), mean corpuscular volume of red blood cells(MCV), serum electrophoresis, B and T-lymphocytes, T-lymphocyte subtypes and phytohemagglutination test were also implemented. Compared to the non-alcoholism, new and old alcoholic inpatients showed statistically significant differences on levels of Hgb and MCV (p<0.05), but showed that T and B-lymphocyte numbers decreased and Helper T cell/Suppressor T cell ratio ($1.6{\pm}0.8$%) increased. Compared to non-alcoholism, phagocytic plaque activities of leukocytes from alcoholic patients decreased significantly and an unusual pattern in phagocytic plaque was observed, showing a strange body and chain shaped phagocytosis. Based upon these results, it is concluded that a phagocytic-plaques of Staphylococcus aureus Cowan I by leukocytes was very simple and useful method for the early immunological determination of phagocytic activities in alcoholic patients without requiring any special equipments.

• Journal of Korean Medical classics
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• v.18 no.4 s.31
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• pp.101-119
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• 2005

금원사대가적태두류완소(金元四大家的泰斗劉完素), 1110년생어하북성하간현(年生於河北省河間縣), 졸어(卒於)1200년(年), 향년(享年)90세(歲). 타통과연구(他通過硏究)${\ulcorner}$황제내경(黃帝內經)${\lrcorner}$화(和)${\ulcorner}$상한론(傷寒論)${\lrcorner}$, 저술료(著述了)${\ulcorner}$소문현기원병식(素問玄機原病式)${\lrcorner}$, ${\ulcorner}$황제소문선명론방(黃帝素問宣明論方)${\lrcorner}$, ${\ulcorner}$소문병기기의보명집(素問病機氣宜保命集)${\lrcorner}$, ${\ulcorner}$상한표본심법류췌(傷寒標本心法類萃)${\lrcorner}$, ${\ulcorner}$상한직격론(傷寒直格論)${\lrcorner}$등저작(等著作). 령외, 응용운기대이론진행연구(應用運氣對理論進行硏究), 주장(主張)‘화열론(火熱論)’, 제출이한량약물치료질병적방법, 사금원시대재의학상(使金元時代在醫學上), 형성료백가쟁명적국면(形成了百家爭鳴的局面). 필자통과대류완소적방제학설급임상경험적연구(筆者通過對劉完素的方劑學說及臨床經驗的硏究), 득출여하결론(得出如下結論): 재방제학설상(在方劑學說上), ${\ulcorner}$황제소문선명론방(黃帝素問宣明論方)${\lrcorner}$중(中), 기사용적(其使用的)${\ulcorner}$상한론(傷寒論)${\lrcorner}$화각가급기제자문운용방제(和各家及其弟子們運用方劑), 공포괄(共包括)366개(個). 대부분주장료이용신고적한약(大部分主張了利用辛苦的寒藥), 래개통울결(來開通鬱結), 조습제열(操濕除熱). ‘상복보양(常服保養)’시인위여기소거주적중국북방(是因爲與其所居住的中國北方), 기후건조(氣候乾操), 인문다식습성강(人們多食濕性强), 차교표한적식물(且較標悍的食物), 소이유사인체장위비조적경향(所以有使人體腸胃秘操的傾向). ${\ulcorner}$황제소문선명론방(黃帝素問宣明論方)${\lrcorner}$적(的)366개방중(個方中), 유산제(有散劑)126개(個), 탕제(湯劑)87개(個), 기중(其中), 지유(只有)18개방가칭지위진정적탕제, 기여도접근위자산(其餘都接近爲煮散). ${\ulcorner}$황제소문선명론방(黃帝素問宣明論方)${\lrcorner}$중소나열적주요방제유(中所羅列的主要方劑有)‘방풍통성산(防風通聖散)’, ‘삼화신우환(三花神佑丸)’, ‘쌍해산(雙解散)’, ‘삼일승기탕(三一承氣湯)’, ‘대금화환(大金花丸)’, ‘익원산(益元散)’, ‘대건중탕(大建中湯)’, ‘당귀룡담환(當歸龍膽丸)’, ‘비방다주조산(秘方茶酒調散)’, ‘계령감로산(桂零甘露散)’, ‘천궁석고탕(川弓石膏湯)’, ‘전성산(全聖散)’, ‘지유탕(地楡湯)’, ‘인참산(人參散)’, ‘작약탕(芍藥湯)’, ‘내통황연탕(內統黃連湯)’, ‘신궁환(神芎丸)’, ‘도환산(倒換散)’등(等). 재임상경험상(在臨床經驗上), 류씨유풍부치료경험(劉氏有豊富治療經驗), 단시유감적시몰유전하일부관우의안방면적저작(但是遺憾的是沒有傳下一部關于醫案方面的著作). 재질병적치료상(在疾病的治療上), 가간출기유독창적견해(可看出其有獨創的見解), 저일점도견우(這一點都見于)${\ulcorner}$소문현기원병식(素問玄機原病式)${\lrcorner}$등이론저작(等理論著作), 우기산견어(尤其散見於)${\ulcorner}$황제소문선명론방(黃帝素問宣明論方)${\lrcorner}$중(中).

• Journal of Advanced Marine Engineering and Technology
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• v.34 no.1
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• pp.62-68
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• 2010

The requirement of high efficiency and low emission for marine diesel engines are being enforced because of air pollution and climate change on the earth. In connection with these, many new technologies are considered. But they are mainly for new building ship. It is necessary to be concerned about the improvement of engine performance for existing ship. In this paper, the simulation program for performance of marine two-stroke diesel engine was developed to predict the deteriorating performance according to elapsed time for existing ship. The result was compared with the result of the program named TOP-CODE which was used by engine maker and checked to be shown good agreement between them.

• Proceedings of the Korea Water Resources Association Conference
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• 2009.05a
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• pp.193-197
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• 2009

오늘날 도시지역의 무분별한 개발로 인해 불투수면적이 증가하여 첨두유량 및 유출용적의 증가와 홍수도달시간을 단축시키고 있으며, 특히 도시유역에서는 하천 홍수위 상승에 의한 외수피해와 순간적인 집중호우에 의해 도로 노면수의 배수불량에서 기인하는 내수피해가 결합되어 홍수피해가 더욱 가중되고 있는 실정이다. 이에 대한 효율적인 조기 대응책으로 도시 수문기상 현상의 변화 및 현황을 파악하여 홍수로 인한 인명 및 재산피해를 최소화할 수 있는 적절한 홍수 예 경보 시스템의 구축을 들 수 있다. 이를 위하여 선진 외국의 경우 기상전문가에 의한 집중호우 현상규명 및 사전예보 기법 확립과 수자원 전문가에 의한 이들 예보자료를 활용한 특정지역의 홍수피해 유무를 사전에 예측하는 기상과 수자원의 학제간 연구가 활발히 진행되고 있다. 국내의 경우 기상 현업에서는 국지성 집중호우 예측과 단시간 강수예보를 위해 수치예보모형, 레이더 및 기상위성을 활용하고 있으나 수자원 분야에서는 예측강우를 활용한 홍수예보에 관한 연구는 매우 미진한 상태이다. 특히 도시홍수의 경우 도달시간이 매우 짧으므로 강수의 초단시간 예보기법을 통한 강수예보의 선행시간 확보는 매우 중요하다. 이를 위해 본 연구에서는 기상레이더 정보와 이류모델을 활용한 초단시간 강수예보의 적용성을 검토하였다. 이류모델은 강우강도 분포를 이류벡터에 따라 이동시키면서 강우의 발달쇠약 회전 등을 고려하여 강수를 예측하는 모형이다. 본 연구에서는 초단시간 강수예보의 적용성 검토를 위해 Least-square fitting 기법으로 레이더 강수를 추정하고, 추정된 강수를 이류모델의 입력장으로 활용하였다. 또한, 도시홍수예보의 활용을 위해 중랑천 유역을 대상으로 초단시간 예측강수의 유역면적평균강우량을 산정하여 적용성을 평가하였다.

• The Journal of the Korea Contents Association
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• v.13 no.10
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• pp.419-426
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• 2013

This study investigates the usefulness of body fix in 4DRT on Liver cancer trying to find tumor tissue's volume and located variations, absorbed dose on tumor and normal tissues. Test subjects 23 patients were agreed these test. These patient's have a 4 dimensional CT scan. We make an acquisition on patients CT image by two types -put on the body fix or not-. Average tumor volume reduced by 0.17% on GTV and 3.2% on CTV and PTV. Tumor's variation reduces 29.8%(anterior and posterior, AP) and 5.31% (upper and lower, UL). The absorbed tumor doses under put on the body fix was a little higher(1.3%) than other. Normal tissues'(normal liver, stomach, Rt. kidney, spinal cord) absorbed dose could be reduced approximately 5%. Therefore, using body fix on 4DRT for liver cancer patient is considered effectively.

• The Journal of the Petrological Society of Korea
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• v.18 no.3
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• pp.181-194
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• 2009

The Cheongryangsan Formation was reported to stratigraphically overlie the Gasongdong Formation and underlie the Dogyedong Formation in the northern part of the Yeongyang subbasin, and be divided into the lower Cheongryangsan Member and the Osipbong Member. But the members have more widely called as the Cheongryangsan Conglomerate and the Osipbong Basalt, because the latter have initially meant that thin basalt flows several times intercalate sedimentary rocks in the northern part but later must consider that they have a very dominant volume in the eastern one. Both formations are based on classifying the stratigraphy and play a role of an excellent key bed for stratigraphic correlation between local spaces in the subbasin dominant absolutely for reddish beds. Both formations play a role of excellent key bed in the northern and northwestern areas of the subbasin; the Osipbong Basalt, the midwestern, eastern and southern ones; the Cheongryangsan Conglomerate, the southeastern one.

• Proceedings of the Korea Water Resources Association Conference
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• 2021.06a
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• pp.59-59
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• 2021

최근 기후변화에 따른 가뭄의 상습화와 농촌용수 수요증가에 대비할 수 있는 가뭄대책의 수립을 통한 용수부족 문제에 대한 근본적인 해소의 필요성 증가하고 있는 가운데 기존 수자원을 효율적으로 활용하기 위한 4차 산업기술을 적용한 순환형 농업용수 관리시스템의 개발이 요구되고 있다. 본 연구는 2017년 가뭄이 극심하였던 충청남도 대사저수지, 풍전저수지와 경기도 마둔저수지에 대하여 기상분석, 관개분석, 수리분석 등을 수행하여 이수관리, 관개만족도, 회귀수의 재이용 등을 예측 관리할 수 있는 순환형 농업용수 관리 시스템을 개발하여 적용하고자, 선제적으로 가뭄 발생 들녘의 용수공급을 위한 농업용 저수지 소유역 순환용수 가용수량을 추정하였다. 2010년부터 2019년까지의 강우유출 모형을 적용하기 위하여 수원, 천안, 이천관측소의 강우, 최고/최저기온, 상대습도, 풍속, 일사량자료를 일자료로 활용하였고, 10년 평균 유출량을 순별로 산정하여 기본자료로 구축하여 주요 취입보 유입수량을 산정하였다. 주요 취입보 유입수량 산정과 취입보의 용적을 산출하기 위하여 시설별 높이차와 하천의 길이 및 폭을 측정하였으며 물수지는 보유용수량과 유입량의 합에서 공급수량을 제외한 값으로 정의하였고, 내용적을 초과하는 경우에는 범람되는 것으로 구현하여 마둔, 대사, 풍전저수지의 임의 지점(하천)별로 순환용수 가용을 위한 모의를 실시하였다. 공간 범위는 평야부 말단부로 선정하였고, 가상으로 약 2m 높이의 임시보를 적용하여 관개기 강우유출수 및 퇴수에 의한 가용수량을 산정하였다. 이를 위하여 하천의 폭과 표고를 이용하여 길이를 산출하여, 내용적을 산출하였다. 소유역별로 TANK 모형적용 결과를 입력자료로 활용하여 일 공급 양수량을 내용적 최대로 하였을 때 회복 기간에 대한 모의를 수행하였다. 강우유출수에 의한 소유역별 가용수량을 4월부터 모의 분석한 결과 유역별로 차이는 발생하지만 만수위에 도달하는 기간은 특이 유역을 제외하고는 약 50일 이상 걸리는 것으로 분석되었고, 관개기가 계속되면서 회복되는 기간이 짧아지는 경향을 보였다. 이를 통해 소유역별 농업용수 부족분 투입을 위한 위치선정과 용수량 판단이 가능할 것으로 예상된다.

• The Journal of Korean Society for Radiation Therapy
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• v.34
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• pp.51-60
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• 2022

Objectives: The purpose is to evaluate dosimetric performance and delivery efficiency of VMAT with Halcyon LINAC for double target spine SBRT Materials and Methods: 12 patients with spine oligometastases were retrospectively studied. Single-isocenter spine SBRT plans was established using Halcyon® with Dual Layer MLC and Truebeam® with High Definition MLC. All patients' plans were created in Eclipse TPS through the identical conditions and optimization. C.I, H.I, G.I (Gradient Index), maximal and volumetric doses to spinal cord and low dose area were evaluated for comparison of both plans. Also, total MU and BOT(Beam On Time) were evaluated. Results: Halcyon plans was no Statistical differences in C.I and H.I. However, the average of G.I was 4.64 for Halcyon, which decreased to 5.5% compared to Truebeam (P<0.001). Halcyon plans demonstrated statistically significant reduced G.I. The average of 50% and 25% isodose volume was 487.56 cc (-3.82%, P<0.001), 1859.45 cc (-4.75%, P<0.001) in Halcyon, respectively. Significantly reduced low dose spill were observed in Halcyon plans. In the evaluation of the spinal cord, the average of Dmean and V10 of Halcyon plans in the sample group with an overlap volume of less than 1 cc was 6.802 Gy (-3.504%, P=0.067), 5.766±1.683 cc (-8.199%, P=0.002), respectively. Halcyon plans demonstrated statistically significant reduced D_mean and V10. For delivery efficiency, MU and BOT(maximum dose rate for each machine), on average, increased in Halcyon plans. However, the average of BOT(800MU/min for each machine) was 648.33 sec for Halcyon (-1.74%, P<0.001). Conclusion: Halcyon plan for double-target spine SBRT demonstrated advantages in the low dose area with a steep dose gradient, while having dosimetrically equivalent target dose distribution and spinal cord protective effect. As a result, Halcyon LINAC produced a dosimetrically improved plan for double-target spine SBRT.

• The Journal of Korean Society for Radiation Therapy
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• v.31 no.1
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• pp.33-41
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• 2019

Purpose : To evaluate the effectiveness of Jaw-tracking(JT) technique in Intensity-modulated radiation therapy(IMRT) and Volumetric-modulated arc therapy(VMAT) for radiation therapy of esophageal cancer by analyzing volume dose of perimetrical normal organs along with the low-dose volume regions. Materials and Method: A total of 27 patients were selected who received radiation therapy for esophageal cancer with using $VitalBeam^{TM}$(Varian Medical System, U.S.A) in our hospital. Using Eclipse system(Ver. 13.6 Varian, U.S.A), radiation treatment planning was set up with Jaw-tracking technique(JT) and Non-Jaw-tracking technique(NJT), and was conducted for the patients with T-shaped Planning target volume(PTV), including Supraclavicular lymph nodes(SCL). PTV was classified into whether celiac area was included or not to identify the influence on the radiation field. To compare the treatment plans, Organ at risk(OAR) was defined to bilateral lung, heart, and spinal cord and evaluated for Conformity index(CI) and Homogeneity index(HI). Portal dosimetry was performed to verify a clinical application using Electronic portal imaging device(EPID) and Gamma analysis was performed with establishing thresholds of radiation field as a parameter, with various range of 0 %, 5 %, and 10 %. Results: All treatment plans were established on gamma pass rates of 95 % with 3 mm/3 % criteria. For a threshold of 10 %, both JT and NJT passed with rate of more than 95 % and both gamma passing rate decreased more than 1 % in IMRT as the low dose threshold decreased to 5 % and 0 %. For the case of JT in IMRT on PTV without celiac area, $V_5$ and $V_{10}$ of both lung showed a decrease by respectively 8.5 % and 5.3 % in average and up to 14.7 %. A $D_{mean}$ decreased by $72.3{\pm}51cGy$, while there was an increase in radiation dose reduction in PTV including celiac area. A $D_{mean}$ of heart decreased by $68.9{\pm}38.5cGy$ and that of spinal cord decreased by $39.7{\pm}30cGy$. For the case of JT in VMAT, $V_5$ decreased by 2.5 % in average in lungs, and also a little amount in heart and spinal cord. Radiation dose reduction of JT showed an increase when PTV includes celiac area in VMAT. Conclusion: In the radiation treatment planning for esophageal cancer, IMRT showed a significant decrease in $V_5$, and $V_{10}$ of both lungs when applying JT, and dose reduction was greater when the irradiated area in low-dose field is larger. Therefore, IMRT is more advantageous in applying JT than VMAT for radiation therapy of esophageal cancer and can protect the normal organs from MLC leakage and transmitted doses in low-dose field.

• Journal of Korean Medical classics
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• v.13 no.2 s.17
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• pp.58-67
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• 2000

통과대문왕팔괘차서도화문왕팔괘방위도적연구(通過對文王八卦次序圖和文王八卦方位圖的硏究). 득도요여하결론(得到了如下結論). 1. 최초명명위문왕팔괘차서도화문왕팔괘방위도적인시소옹(最初命名爲文王八卦次序圖和文王八卦方位圖的人是邵雍). 문왕팔괘차서도화문왕팔괘방위도수연몰유시문왕소화적확체적근거(文王八卦次序圖和文王八卦方位圖雖然沒有是文王所畵的確切的根據), 단시종추연복희이(但是從推演伏羲易), 동사상결합(同事相結合), 최종확립여금적역학체계적인시문왕(最終確立如今的易學體系的人是文王). 이차환부합현금적역리(而且還符合現今的易理), 인차구유일정설복력(因此具有一定說服力). 2. 재문왕팔괘차서도중삼남유일양이음구성(在文王八卦次序圖中三男由一陽二陰構成). 삼녀유일음이양구성(三女由一陰二陽構成). 저가이용음양호근적원리진행설명(這可以用陰陽互根的原理進行說明). 3. 복희팔괘방위도현시모종공간상(伏羲八卦方位圖顯示某種空間相). 이문왕팔괘방위도칙현시사시(而文王八卦方位圖則顯示四時). 팔절적변화화만물생장적류행주기등시간상적변화(八節的變化和萬物生長的流行周期等時間上的變化). 4. 문왕팔괘방위도동사시적오행상일치(文王八卦方位圖同四時的五行相一致). 시상생관계(是相生關係), 팔괘당중각유양개목김토(八卦當中各有兩개木金土). 시유우형흔왕성(是由于形흔旺盛), 수화각유일개시유우기흔왕성(水火各有一개是由于氣흔旺盛). 5. 문왕팔괘방위도재표면상간호상시오행상생적관계(文王八卦方位圖在表面上看好象是五行相生的關係). 단시(但是), 상호성대면적팔괘적오행도성상극관계(相互成對面的八卦的五行都成相剋關係). 화동측상임적감수(和東側相臨的坎水) 간토(艮土) 진목(震木) 손목도시성상극관계(孫木都是成相剋關係). 종차가이지도상극시발전만물적주체(從此可以知道相剋是發展萬物的主體). 6. 대우복희팔괘전화위문왕팔괘적원리(對于伏羲八卦轉化爲文王八卦的原理), 수유각종이론제출(雖有各種理論提出). 단시상무확체적설법(但是尙無確切的說法). 7. 복희팔괘주요체현천도화외상등(伏羲八卦主要體現天道和外象等), 문왕팔괘측체현인사화내정등(文王八卦側體現人事和內情等). 8. 복희팔괘위체(伏羲八卦爲體), 문왕팔괘위용(文王八卦爲用). 복희팔괘중(伏羲八卦中), 위변화적주체적천지즉건곤위우중축(爲變化的主體的天地卽乾坤位于中軸). 문왕팔괘중(文王八卦中), 위변화적대용적일월즉감리위우중축(位變化的大用的日月卽坎離位于中軸). 9. 복희팔괘도속우표현춘천적변화지상적제일괘도(伏羲八卦圖屬于表現春天的變化之象的第一掛圖), 생괘도화창조도(生掛圖和倉曹圖), 문왕팔괘도칙속우표현하천적변화지상적제이괘도(文王八卦圖則屬于表現夏天的變化之象的第二掛圖), 장괘도화발전도(長掛圖和發展圖). 10. 문왕팔괘도시류행이치기용적역지용(文王八卦圖是流行以致其用的易之用), 표현무질서화혼란(表現無秩序和混亂), 위화여괴리상호란무적난음난양지상(韋和與乖離相互亂舞的亂陰亂陽之象). 11. 문왕팔괘도화낙서적변화원리상일치(文王八卦圖和洛書的變化原理相一致), 가이장낙서적수직접대응도문왕팔괘도중(可以將洛書的數直接對應到文王八卦圖中). 우명낙서팔괘도(又名洛書八卦圖). 구수도혹일구역(九數圖或一九易). 12. 문왕팔괘도적상대응적수자지합도위십(文王八卦圖的相對應的數字之合都爲十). 저예시료성괘도십수도적출현(這豫示了成掛圖十數圖的出現).