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Influence of Delayed Gastric Emptying in Radiotherapy after a Subtotal Gastrectomy (위부분절제술 후 방사선치료에서 음식물 배출지연에 따른 영향)

  • Kim, Dong-Hyun;Kim, Won-Taek;Lee, Mi-Ran;Ki, Yong-Gan;Nam, Ji-Ho;Park, Dal;Jeon, Ho-Sang;Jeon, Kye-Rok;Kim, Dong-Won
    • Radiation Oncology Journal
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    • v.27 no.4
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    • pp.194-200
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    • 2009
  • Purpose: This aim of this study was to evaluate changes in gastric volume and organ position as a result of delayed gastric emptying after a subtotal gastrectomy performed as part of the treatment of stomach cancer. Materials and Methods: The medical records of 32 patients who underwent concurrent chemoradiotherapy after a subtotal gastrectomy from March 2005 to December 2008 were reviewed. Of these, 5 patients that had more than 50 cc of residual gastric food detected at computed tomography (CT) simulation, were retrospectively enrolled in this study. Gastric volume and organ location was measured from CT images obtained before radiotherapy, twice weekly. In addition, authors evaluated the change of radiation dose distribution to planning the target volume and normal organ in a constant radiation therapy plan regardless of gastric volume variation. Results: A variation in the gastric volume was observed during the radiotherapy period (64.2~340.8 cc; mean, 188.2 cc). According to the change in gastric volume, the location of the left kidney was shifted up to 0.7 - 2.2 cm (mean, 1.2 cm) in the z-axis. Under-dose to planning target volume (V43, 79.5${\pm}$10.4%) and over-dose to left kidney (V20, 34.1${\pm}$12.1%; Mean dose, 23.5${\pm}$8.3 Gy) was expected, given that gastric volume change due to delayed gastric emptying wasn't taken into account. Conclusion: This study has shown that a great change in gastric volume and left kidney location may occur during the radiation therapy period following a subtotal gastrectomy, as a result of delayed gastric emptying. Detection of patients who experienced delayed gastric emptying and the application of gastric volume variation to radiation therapy planning will be very important.

Examination about Utility of Prone Position in PET/CT of Stomach Cancer Patient (위암 환자의 양전자 방출 컴퓨터 단층 검사에서 복와위(伏臥位) 촬영의 유용성에 대한 연구)

  • NamKoong, Hyuk;Park, Hoon-Hee;Oh, Shin-Hyun;Bahn, Yung-Kag;Kim, Jung-Yul;Lim, Han-Sang;Lee, Chang-Ho
    • The Korean Journal of Nuclear Medicine Technology
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    • v.14 no.2
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    • pp.93-99
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    • 2010
  • Purpose: Currently, PET/CT scan has been known to provide useful information to both preoperative and postoperative examination of cancer patients. Contracted stomach by the long fasting could cause difficulties of interpretation because of its size on reconstructed image data. To solve this problem, after the whole body PET/CT scan, patients were administrated in drinking 300 mL of water to expand stomach and performed additional scan on stomach region. Not only PET/CT scan but also CT performs this water-administration, and patients were take oral solution to make stomach expand for stomach cancer. When this scan performed, patients lay supine position. In this study, we evaluated the capacity of stomach through PET/CT scan with drinking water performed in supine and prone position so that we can distinguish exact location of cancer around pylorus and inferior wall of stomach. Furthermore, image data from supine and prone positions were analyzed the difference of volume of stomach through the change of standardized uptake values. Materials and Methods: From July 2009 to January 2010 in severance hospital, 30 patients who were diagnosed as early gastric cancer or advanced gastric cancer were chosen. All patients had PET/CT scan before the operation and have had follow-up PET/CT. The patients fast for at least 8 hours, and had an injection intravenously with $^{18}F$-FDG, 7.4 MBq (0.2 mCi/kg) per kilogram. They were rested for 60 minutes. Before the examination, all patients were administrated to drink water for 300 mL Patients had PET/CT scan with supine position around the region of stomach, whole body, and around the region of stomach with prone position after drinking another 300 mL of water respectively. Results: As a results of comparison between stomach capacity of 30 patients in supine and prone position, the study draw results that average capacity of stomach body was 460.29 $mm^2$ in supine position, and 641.39 $mm^2$ in prone position for 30 patients. The change of capacity shows 41.3% expanded in prone position. And there was no noticeable difference at maximum standardized uptake values in supine position and prone position. Conclusion: As results, stomach would have more expanded capacity in prone position than supine position. For patients who have physical disabilities to move freely, additional scan in prone position will be obstacle to perform. However, if additional scan in supine position add with the scan in prone position, it will be easier to diagnose stomach cancer. Moreover, we believe that this study will help the research for inventing support tools for patients who have physical disabilities in prone position.

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Detection of Radial Pulse Wave by Photoplethysmogram (광전용적맥파를 이용한 요골동맥 맥파 검출)

  • 정동근;김광년;연규선;최병철;서덕준
    • Journal of Life Science
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    • v.13 no.1
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    • pp.42-46
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    • 2003
  • Photoplethysmogram is widely used to measure heart rate and arterial blood oxygen saturation in human. This paper describes radial pulse waves recorded by photoplethysmogram with 940 nm wavelength infra red light. Radial pulse waves were varied according to the recording site. When recorded on the skin over radial artery, the radial pulse wave was inverted, comparing to the photoplethysmogram at fingertip. The mechanism of inverted pulse wave seemed to be caused by the change of the blood volume in the subcutaneous tissue between radial artery and the skin, which was reduced during systolic period and increased during diastolic period of the cardiac cycle. These results suggest that radial arterial wall may reflect infra red ray.

Effects of Soil Bulk Density on Saturated Hydraulic Conductivity and Solute Elution Patterns (토양의 용적밀도에 따른 포화수리전도도 및 음이온의 용출양상)

  • Kim, Pil-Joo;Lee, Do-Kyoung;Chung, Doug-Young
    • Korean Journal of Soil Science and Fertilizer
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    • v.30 no.3
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    • pp.234-241
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    • 1997
  • The effects of bulk densities(${\rho}_b$) on saturated hydraulic conductivity (Ksat) and solute elution patterns were investigated from five different bulk densities ranging from $1.1Mg/m^3$ to $1.5Mg/m^3$ with each increment of $0.1Mg/m^3$. The hydraulic conductivities observed were divided into two stages: (1) a linearly decrease with increase in bulk density up to $1.4Mg/m^3$, (2) a steady state where the bulk density is greater than $1.4Mg/m^3$. Using the saturated hydraulic conductivity at the steady state, we figured out the equation describing the correlation between bulk densities(${\rho}_b$) and saturated hydraulic conductivity(Ksat) as follows: $Ksat=-19.2({\rho}_b{^2})+6{\rho}_b+15.5$, (r=0.985). Electrical conductivity(EC) measured from the leachate of the soil column showed that EC at the same pore volume were decreased with an increase in the bulk density from $1.2g/cm^3$, $1.5g/cm^3$, as shown in the time taken to collect the same pore volume at each respective bulk density. The maximum relative concentrations (C/Co=1) from the breakthrough curves for the anions of $Cl^-$, $NO_3{^-}$ and $SO_4{^{2-}}$, which are weakly adsorbed on the soil particles, moved to the right of the graph, while a distinctive retardation occurs at the bulk density between $1.3Mg/m^3$ and $1.4Mg/m^3$. The time taken to recover about 90% of indigenous sulphate was approximately twice as those of chloride and nitrate, resulting in slightly stronger adsorption characteristics for sorption sites on the soil surface. Thus, we can conclude that the salt accumulation in green house soil might be significantly influenced by it's bulk density at the soil depth, as well as the adsorption capacity of ions for the sorption sites in soils.

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Blood Pictures and Histochemical Properties of the Gastrointestinal Mucous Cells in the Viper (까치 살모사(Agkistrodon saxutilis)의 혈액학적 성상과 위장관 점막세포의 조직화학적 연구)

  • 노영복
    • The Korean Journal of Zoology
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    • v.36 no.2
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    • pp.159-174
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    • 1993
  • 까치 살모사(AEkistrodon snatilis)의 활동기와 동면기에서 일반적인 혈액성상과 혈액내 가스함량의 변화 또한 위장관 점액세포에 대한 형태적 및 조직화학적 변화 양상을 규명 비교하고자 한다 활동기와 동면기에 까치 살모사의 혈액내 총이산화탄소량(TCO2). 이산화탄소부분압(PCO2), 산소압(PO2)과 pH는 활동기보다 동면기에 증가하였으며, 적혈구수, 혈색소, 적혈구 용적 백분율은 활동기보다 동면기에 약간 증가하는 경향이었다. 또한 백혈구수는 활동기보다 동면기에 뚜렷한 감소를 보였다 활동기와 동면기의 위점막에서는 현저한 차이는 없으나, 소장 점막은 동면기에 그 주름수가 감소하고 높이가 낮아지며 점액세포가 위축되었으며, 위 표면 점액세포는 활동기에 중성 점액질과 약간의 Sialomucin을 포함한 산성 점액질로 구성되었으나 동면기에는 중성 점액질과 Sialomucin이 약간 감소하였다 위점액경세포는 활동기에 중성 점액질만을 포함하고 있었으나. 동면기에는Sialomucin을 포함한 산성 점액질이 소량 검출되었다 소장 점액세포는 활동기에 산성점액질과 중성 점액질로 구성되었으며. 산성 점액질에는 Sulfomucin과 Sialomucirr이 포함되어 있었으나 동면기에는 Sulfomucin과 Sialomucin이 다소 감소하는 경향이었다 주사전자현미경 관찰을 통한 까치 살모사의 위장관 표면 상피세포의 미세구조적 변화는 각동면기 별로 차이를 인정할 수가 있었다. 위장관점 막 상피세포는 활동기에 비해 동면기에 상당한 구조적 위축현상을 보이는 경향을 알 수 있다.

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Age-related Changes of the Finger Photoplethysmogram in Frequency Domain Analysis (연령증가에 따른 지첨용적맥파의 주파수 영역에서의 변화)

  • Nam, Tong-Hyun;Park, Young-Bae;Park, Young-Jae;Shin, Sang-Hoon
    • The Journal of the Society of Korean Medicine Diagnostics
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    • v.12 no.1
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    • pp.42-62
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    • 2008
  • Objectives: It is well known that some parameters of the photoplethysmogram (PPG) acquired by time domain contour analysis can be used as markers of vascular aging. But the previous studies that have been performed for frequency domain analysis of the PPG to date have provided only restrictive and fragmentary information. The aim of the present investigation was to determine whether the harmonics extracted from the PPG using a fast Fourier transformation could be used as an index of vascular aging. Methods: The PPG was measured in 600 recruited subjects for 30 second durations, To grasp the gross age-related change of the PPG waveform, we grouped subjects according to gender and age and averaged the PPG signal of one pulse cycle. To calculate the conventional indices of vascular aging, we selected the 5-6 cycles of pulse that the baseline was relatively stable and then acquired the coordinates of the inflection points. For the frequency domain analysis we performed a power spectral analysis on the PPG signals for 30 seconds using a fast Fourier transformation and dissociated the harmonic components from the PPG signals. Results: A final number of 390 subjects (174 males and 216 females) were included in the statistical analysis. The normalized power of the harmonics decreased with age and on a logarithmic scale reduction of the normalized power in the third (r=-0.492, P<0.0001), fourth (r=-0.621, P<0.0001) and fifth harmonic (r=-0.487, P<0.0001) was prominent. From a multiple linear regression analysis, Stiffness index, reflection index and corrected up-stroke time influenced the normalized power of the harmonics on a logarithmic scale. Conclusions: The normalized harmonic power decreased with age in healthy subjects and may be less error prone due to the essential attributes of frequency domain analysis. Therefore, we expect that the normalized harmonic power density can be useful as a vascular aging marker.

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Diets of the Rock Trout, Agrammus agrammus, in the Shore Area of Tongbaeksom, Pusan (부산 동백점 연안에 서식하는 노래미 Agrammus agrammus의 먹이생물)

  • KIM Chong Kawn;KANG Yong Joo
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.19 no.5
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    • pp.411-422
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    • 1986
  • Diets of the rock trout, Agrammus agrammus, in the shore area of Tongbaeksom, Pusan over the period of July 1981 to June 1982 were studied. Specimens were sampled by angling. Stomach analysis showed that the rock trout fed mainly on epibenthic food in the littoral zone along the coast of Tongbaeksom. The food organisms of the enviornment were studied by means of underwater sampling around the angling area for this study. Although the food items of the fish changed slightly with season and age-group, main food items were Amphipoda (Gammaridae, Caprellidae) and Isopoda (Sphaeromidae, Idotheidae). This suggests that the diets of A. agrammus mainly comprised epibenthic food. Food diversity increased with age. The fish almost consummed on smaller food in size, but had selective predation according to food size, i. e. on larger food as age increases. These data provide additional support for the importance of the detritus-benthos-consummer type food chain.

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A Nutrition Survey of Mountain Villagers (일부(一部) 산촌지역(山村地域) 주민(住民)의 영양실태(營養實態) 조사연구(調査硏究))

  • Cho, Young-Sook;Koh, Moo-Seok
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.15 no.2
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    • pp.181-189
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    • 1986
  • This nutrition survey was carried out twice(Spring and autumn) in Sam Chung-Ri, Song Kwang Myun, Soong Ju-Gun. The food intakes of 92 family members were measured by weighing method. Also 45 adults were examined for anthropometric, blood content and blood pressure. The results abtained were summarized as follows; In vegetable foods, the intake of rice was high, but that of legumina and other cereals was low. In animal foods, the intake of milk and eggs was low, and that of oils and fats was very low. However, the food intake between spring and autumn showed remarkable difference. The average intake of calorie, protein, Ca, Fe and vitamin $B_2$ except vitamin $B_1$ and niacin was below the RDAs. The percentage of carbohydrate, protein and fat for energy was 82.2, 11.6 and 6.2%, respectively. The results of anthropometry of height, weight and chestcircumference showed that both sexes Were below Korean Standards. The concentration of Hb & Hct was normal in both sexes, and the rate of anemia was low. The concentrations of plasma glucose, protein, lipids, and blood pressure were normal in both sexes. In case of male, the correlation between plasma albumin and nutrients intake was significant, but the case of female showed different tendency. In case of male, the correlation between weight, height and plasma protein was also significant but the case of female showed different tendency. The rate of parasite infection was very low $(2.17%{\ldots}3.26%)$

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Verification of Soil Volumetric Water Content Measured by TDR, FDR Sensors (TDR, FDR 센서로 측정한 토양수분 함량의 정확성 검정)

  • Hur, Seung-Oh;Jung, Kang-Ho;Park, Chan-Won;Ha, Sang-Keon;Kim, Jeong-Gyu
    • Proceedings of the Korea Water Resources Association Conference
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    • 2007.05a
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    • pp.229-235
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    • 2007
  • 관개나 수분수지 규명을 위한 기본적인 자료는 토양수분 함량이다. 그러나, 포장상태에서의 토양수분 함량은 직접 측정하는 것이 쉽지 않기 때문에 많은 경우 건조기를 이용한 중량수분 함량측정 방법을 이용하거나 토양수분 포텐셜 측정용인 텐시오미터를 이용한 토양수분의 에너지 특성을 관개에 활용하는 것이 현실이었다. 중량수분 함량은 시료를 채취해서 건조하기 때문에 시료채취 당시의 토양수분 함량을 아는 것이 어렵고, 토양수분 포텐셜은 에너지를 측정하는 것이기 때문에 이 역시 토양의 수분함량을 얻는 것이 불가능 하다. 따라서, 최근에 이런 측정상의 어려움을 극복하기 위해 여러 나라에서 포장에서의 토양수분 함량을 직접 측정하는 다양한 센서를 개발하고 있고 있다. 그 중 몇 가지는 현재 우리나라에 공급되고 있는데, 가격 등의 문제로 별로 알려져 있지는 않다. 센서는 현장에서 수분함량을 파악할 수 있는 장점이 있기 때문에 관개에 직접 적용이 가능하며 자동화시설이나 수분수지 모형 산정에도 활용할 수 있다. 본 시험은 우리나라에 소개되어 있는 몇 가지의 토양수분 측정용 센서를 현장에서 코어를 이용해 측정한 용적수분 함량과 비교하여 센서의 정확도나 이용 가능성을 검정하고자 하였다. 코어를 이용해 실측한 토양 용적수분 함량과 비교하고자 7종의 센서를 선택해 실험에 이용하였다. 가격이 비싼 것으로 알려진 TDR 형태의 센서가 2종이었으며, 나머지 5종은 FDR 형태의 센서였다. TDR 센서는 Soilmoisture사에서 제작한 MiniTrase와 Imko 사의 Trime이고, FDR은 Sentek사에서 개발한 EasyAG, EnviroSCAN과 Delta-T사에서 제작한 PR-1과 WET-2 및 Decagon사에서 제작한 $ECH_2O$ 센서였다. 실헙방법은 본량사양토인 포장에서 건조한 상태인 시험구와 물이 포화된 시험구를 만들어 놓고, 그곳에서 센서 종류별로, 측정 깊이별로 토양의 용적수분 함량을 측정하고, 센서로 측정한 위치 바로 옆에서 코어를 이용해 토양시료를 채취하고 이를 건조기에 건조해 용적수분 함량을 측정하였다. 비교결과 TDR인 MiniTrase가 결정계수$(r^2)$가 0.964이고 표준오차(SE)가 0.01로 좋은 결과를 보여줬고 WET-2가 $r^2$와 SE가 0.932와 0.013이였으며 EasyAG는 0.877과 0.0211, EnviroSCAN은 0.803과 0.0259의 값을 보였다. 일반적으로 토양수분 함량 측정오차가 1% 미만인 센서가 정확한 수분함량 해석을 유도할 것이지만 위의 센서 중 MiniTrase를 비롯한 4개의 센서 정도가 토양의 수분 함량을 측정하는데 유용할 것이라는 결론을 얻었다.

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The Influence on Corelation between Photo-plethysmograph Variability and Heart Rate Variability by Temperature Variation (온도변이가 PV와 HRV의 상관관계에 미치는 영향에 관한 연구)

  • Min, Se-Dong;Lee, Chung-Keun;Shin, Hang-Sik;Lee, Byoung-Woo;Kim, Jin-Kwon;Park, Hyun-Cheol;Lee, Myoung-Ho
    • Proceedings of the KIEE Conference
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    • 2008.07a
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    • pp.2007-2009
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    • 2008
  • 본 논문에서는 인체에 열을 가했을 때 심전도(ECG) 신호에서 얻어진 Heart Rate Variability(HRV)와 광전용적맥파(PPG)에서 얻어진 Photoplethymograph Variability(PV)의 상관관계를 보기 위하여 피실험자가 상온에서 누워 있을때와 65$^{\circ}C$의 온도로 누워있을때의 심전도와 PPG를 측정하여 두 파라메터의 상관관계를 분석하여 그 효용성을 평가하였다. 이를 위하여 우선 신체 건강한 26세에서 32세까지 총 3명의 남성을 대상으로 하여 ECG와 PPG를 위와 같은 조건에서 측정한 다음, 두 신호로부터 피크를 검출하고, 피크 간격을 시계열 신호로 변환하여 HRV와 PV신호를 얻어 내었다. 또한 얻어진 HRV신호와 PV신호의 주파수 분석을 통하여 HF 및 LF성분을 비교하여 HRV와 PV의 상관관계를 비교하였다.

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