• Title/Summary/Keyword: 위축성

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Effect of Helicobacter pylori Eradication on the Prevention of Gastric Cancer in the General Population with or without Precancerous Lesions: A Meta-analysis (일반 인구 집단에서 전암성 병변 유무에 따른 헬리코박터 제균 치료의 위암 예방 효과 연구: 메타분석)

  • Kang, Soo Jin;Shin, Cheol Min;Kang, Seung Joo
    • Journal of Digestive Cancer Reports
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    • v.8 no.2
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    • pp.81-90
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    • 2020
  • We performed a comprehensive meta-analysis on whether Helicobacter pylori (H. pylori) eradication can prevent gastric cancer in individuals with precancerous lesions (chronic atrophic gastritis, intestinal metaplasia, and dysplasia). The studies evaluating the effect of H. pylori eradication on gastric cancer were searched from PubMed, KoreaMed, EMBASE, and Cochrane Library. Subgroup analyses by precancerous lesions, regions and follow-up time were performed. Six randomized clinical trials were included. In the overall population, H. pylori eradication significantly decreased the risk of gastric cancer (risk ratio [RR]=0.56; 95% confidence interval [CI]: 0.41-0.77, p<0.01). Eradication therapy significantly reduced the risk of gastric cancer in Asian and group who followed up more than 10 years (RR=0.51; 95% CI: 0.35-0.73, p<0.01; I2=0%, p=0.46). However, subgroup analysis according to the precancerous lesions did not show any significant results (p>0.05). In the general population especially in Asian population, H. pylori eradication can reduce the risk of gastric cancer. The effect of the eradication treatment is remarkable upon the long-term follow-up. In contrast, there is insufficient evidence whether the eradication should be recommended for the individuals with precancerous lesions.

Protective Antibodies and Immunity elicited by Immunization with Outer Membrane Protein H of Pasteurella multocida in Mice (Pasteurella multocida의 외막 단백질 H에 의해 유도되는 방어적 항체와 면역)

  • Kwon, Moo-Sik;Kim, Young-Bong;Lee, Jeong-Min
    • Korean Journal of Microbiology
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    • v.43 no.1
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    • pp.7-13
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    • 2007
  • Pasteurella multocida is one of the important animal pathogen causing widespread infections in various domestic animals. In swine, it causes severe respiratory diseases such as atrophic rhinitis and pneumonic pasteurellosis. To develop the efficient subunit vaccine against swine atrophic rhinitis, we investigated protective antibodies and humoral immunity of outer membrane protein H (OmpH) which is one of the major outer membrane proteins in P. multocida. Outer membrane fraction of P. multocida was immunologically detectable using antisera from both mice groups vaccinated by formalin-killed whole cells and by commercial vaccine. The expression vector for production of recombinant OmpH was constructed and the recombinant OmpH was expressed and purified from E. coli. Recombinant OmpH showed high antigenic and immunogenic properties in mice vaccination and ELISA with antisera.

The Moderating Effect of Peer Attachment and Parenting Attitude in the Relationship between Social Withdrawal and Life Satisfaction of Adolescents (청소년의 사회적 위축과 삶의 만족도의 관계에서 또래애착 및 부모 양육 태도의 조절효과 분석)

  • Kim, In
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.22 no.1
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    • pp.681-690
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    • 2021
  • The aim of this study is to suggest the direction of psychosocial intervention by investigation. To this end, this study examined the moderating effect of peer attachment and patients' positive attitude on the relationship between social withdrawal and life satisfaction of adolescents. Data was obtained from the Korean Children and Youth Panel Survey, and study subjects included 2,409 first grade middle school students. Data was analyzed using the SPSS 25 program, and frequency analysis, descriptive statistical analysis, correlation analysis and hierarchical regression analysis were conducted. The results of the study are as follows: First, psychological withdrawal in the social relationship had a significant negative effect on the life satisfaction of adolescents. Second, peer attachment did not have a moderating effect on the relationship between social withdrawal and life satisfaction of adolescents. Third, positive parenting attitude had a moderating effect on the relationship between social withdrawal and life satisfaction of adolescents. The high-positive parenting attitude group showed less decline in life satisfaction even if social withdrawal was high compared to the low-positive parenting attitude group. Based on these results, we provide effective direction of intervention to elevate the life satisfaction of adolescents experiencing social withdrawal.

The Relations among Social Withdrawal, Peer Victimization, and Depression in Middle School Students: The Moderating Effect of Classroom-level Discrimination (중학생의 사회적 위축, 또래괴롭힘 피해, 우울 간의 관계: 학급별 차별수준의 조절효과)

  • Choi, Eun-ji;Song, Keng-hie;Lee, Seung-yeon
    • Korean Journal of School Psychology
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    • v.18 no.2
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    • pp.249-267
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    • 2021
  • This study examined how social withdrawal as an individual factor and discrimination as a contextual factor contributed to depression caused by peer victimization among middle school students. Self-reported data of 1,611 students from 86 classrooms in 7 middle schools was analyzed, using multilevel path analysis. The results indicate that peer victimization had a significant partial mediating effect on the relation between social withdrawal and depression at the individual level. Social withdrawal had a direct positive effect on depression as well as an indirect positive effect on depression via high levels of peer victimization. Discrimination also positively predicted peer victimization at the classroom level. Moreover, classroom-level discrimination moderated the individual-level relations between social withdrawal and peer victimization. The relation between social withdrawal and peer victimization was much stronger as the levels of discrimination in the classroom were higher. These findings shed light on the importance of considering both individual and contextual factors when intervening to prevent peer victimization.

Social Withdrawal and Friendships in Childhood (학령기 아동의 사회적 위축성과 친구관계)

  • Shin, Yoolim
    • Korean Journal of Child Studies
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    • v.28 no.5
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    • pp.193-207
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    • 2007
  • The present study investigated the influence of withdrawal on children's best friendship including prevalence of best friendship, friendship quality, and friends' psychosocial characteristics. Subjects were 471 fifth and sixth graders recruited from two public schools. The peer nomination index was used to assess peer victimization, withdrawal, and prosocial behavior. Peer rejection and acceptance were also measured. Children reported on the quality of their friendships using the Friendship Quality Scale(Bukowsi et al., 1994). Results showed that compared to control group, withdrawn children had fewer best friends and perceived their friendship quality more negatively. Moreover, withdrawn children are similar with their best friends in respect with prosocial behavior, withdrawal, peer victimization, and peer rejection level.

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A Case study on the improvement in atrophic gastritis patient using Ortho-Cellular Nutrition Therapy (OCNT) (세포교정영양요법(OCNT)을 이용한 위축성 위염 환자 개선 사례 연구)

  • KangHwa Lee
    • CELLMED
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    • v.13 no.16
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    • pp.60.1-60.3
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    • 2023
  • Objective: Case report on the improvement of atrophic gastritis through application of Ortho-Cellular Nutrition Therapy (OCNT) Method: OCNT was applied to a Korean female in her 40s suffering from severe atrophic gastritis. Results: Atrophic gastritis was improved following the implementation of OCNT. Conclusion: Application of OCNT can be helpful in alleviation of symptoms in patients displaying atrophic gastritis symptoms.

Prosthetic rehabilitation of an oligodontia patient with atrophic maxilla (위축된 상악골을 가진 부분무치증 환자의 보철수복)

  • Chi, Seung-Seok;Kim, Ye-Jin;Kang, Hyeon-Goo;Ko, Kyung-Ho;Huh, Yoon-Hyuk;Park, Chan-Jin;Cho, Lee-Ra
    • The Journal of Korean Academy of Prosthodontics
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    • v.59 no.2
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    • pp.238-247
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    • 2021
  • Congenital tooth agenesis is the most common developmental dental anomaly, of which oligodontia is defined as the absence of six or more permanent teeth, except the third molars. Tooth agenesis causes malocclusion, alveolar atrophy, aesthetic and psychosocial problems. This clinical report describes a multidisciplinary treatment for a patient diagnosed as oligodontia, who exhibited absence of 14 permanent teeth, atrophy of maxillary alveolar bone, and mandibular protrusion. Restoration space was secured and tooth axis was improved by the extraction of deciduous teeth and orthodontic treatment. However, edge-to-edge bite of posterior teeth and arch dimension discrepancy due to atrophic maxilla was remained. To restore the aesthetics and functionality, implant retained prosthesis was planned. Considering minimal bone grafts, location and number of dental implants and prostheses design were determined. Through the gradual adjustment of provisional restoration, the appropriate centric and eccentric occlusion was reflected into a definitive prosthesis. Currently, stable functional results were attained, however, regular follow up and maintenance care over lifetimes should be performed.

Asymmetric Effects of Inflation Uncertainty on Facilities Investment (인플레이션 불확실성의 기업 설비투자에 대한 비대칭적 효과 분석)

  • Son, Minkyu;Chang, Youngjae
    • The Korean Journal of Applied Statistics
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    • v.27 no.1
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    • pp.123-132
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    • 2014
  • Inflation uncertainty is known to have deleterious effects on facilities investment by disturbing the corporate decision on the opportunity cost of investment. In this paper, we test the validity of this hypothesis in Korea by estimating the inflation uncertainty with both a time-varing parameter model with GARCH disturbances and the relative price volatility and then, estimate the facilities investment equation which includes those uncertainty indicators. The uncertainty indexes estimated by the above-mentioned methods continue to fluctuate even after the inflation rate has dropped dramatically reflecting the structural changes of Korea's economy since the financial crisis in 1997. As a result of estimation of the investment equation by both OLS and GMM, we find the inflation uncertainty has a negative effect on facilities investment with a statistical significance. Moreover, by means of Markov-switching regression model utilized to verify the non-linearity of this relationship, we draw a conclusion that this negative effect of inflation uncertainty heightens asymmetrically during the downturn periods of business cycle.

A case of Dyke-Davidoff-Masson syndrome in Korea (국소적 경련과 편마비를 동반한 Dyke-Davidoff-Masson 증후군 1례)

  • Lee, Jun Hwa;Lee, Zee Ihn;Kim, Ho Kyun;Kwon, Soon Hak
    • Clinical and Experimental Pediatrics
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    • v.49 no.2
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    • pp.208-211
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    • 2006
  • Dyke-Davidoff-Masson Syndrome (DDMS) is a rare condition characterized by asymmetry of cerebral hemispheric growth with atrophy on one side, ipsilateral compensatory osseous hypertrophy, and contralateral hemiparesis. We experienced a 17 month-old male who presented with left focal clonic or tonic-clonic seizures accompanied by left hemiparesis and developmental delay. Brain MRIs demonstrated progressive atrophy of the right cerebral hemisphere with dilatation of the lateral ventricle, expansion of the ipsilateral frontal sinus with calvarial thickening, and elevation of the petrous pyramid and orbital roof. Brain SPECT showed a decreased volume of the right hemisphere with reduced blood flow. We therefore report a case of DDMS with a review of the literature.

An infectious virus isolated from soybeans (대두위축병원 바이러스에 관한 연구)

  • Lee Soon Hyung;Lee Min Hyo;Tochihara Hiroshi
    • Korean journal of applied entomology
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    • v.19 no.3 s.44
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    • pp.175-179
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    • 1980
  • Soybean stunt virus (SSV) was newly isolated in Korea from naturally infected soybeans (Glycine max). The main symptoms caused by this virus on soybean cultivars are crinkling, mild mottling and reduction in plant size. This virus induced local lesion on the inoculated leaves of Chenopodium amaranticolor, C quinoa and Vigna sinensis, and mosaic symptoms on Nicotiana tabacum (Bright yellow, KY-57). The virus was inactivated at 60C, and was infectious at dilution of $10^3$. Extract juice became infective 3 days later at room temperature. The virus was transmitted by green peach apid (Myzus persicae). This virus closely is related serologically to cucumber mosaic virus. The virus particles observed in the electron microscopy were spherical types of 30mm in diameter.

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