• Journal of Gastric Cancer
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• v.9 no.3
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• pp.78-87
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• 2009

Serum pepsinogen (sPG) is a marker of gastric mucosal atrophy, a condition that has been associated with an increased risk of gastric neoplasia. A low sPGI level and a low PG I/II ratio have been associated with severe gastric atrophy, and are frequently found in gastric cancer. Because the prevalence of gastric cancer is high in Korea, it would be convenient if a good biomarker for gastric cancer were developed. Two studies recently investigated the efficacy of sPG along with Helicobacter pylori (H. pylori) as a screening tool for gastric cancer. In these studies, sPG was measured using a Latex enhanced Turbidimetric Immunoassay. We found that H. pylori IgG status, age and gender were associated with serum pepsinogen levels. Thus, to increase the ability of the PG I/II ratio to detect atrophic gastritis, the cutoff value for the PG I/II ratio should be stratified according to the H. pylori IgG status. In addition, a PG I/II ratio ($\leq3.0$), which has been widely used as an international standard for gastric cancer, was found to be a reliable marker for the detection of gastric dysplasia or gastric cancer, especially of the intestinal type. The efficacy of the test in Korea was lower than the efficacy in Japan. However, the detecting power of a PG I/II ratio ($\leq3.0$) was significantly increased in the presence of H. pylori. The ratio together with H. pylori psotivitiy could provide a means of identifying persons at high risk of developing gastric cancer in Korea.

• Environmental and Resource Economics Review
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• v.5 no.2
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• pp.279-290
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• 1996

정부의 환경규제로 인하여 한국 제조업의 기업들이 공해방지시설을 의무적으로 설치해야할 경우, 이는 생산비증가와 신규투자의 위축 및 생산요소간 조합비율에 영향을 미침으로써 직 간접적으로 생산성의 감소를 초래한다. 본 연구에서는 인과추정법(因果推定法)으로 측정한 그레이 (Gray, 1987)의 모형을 통하여 환경규제가 한국 제조업의 생산성에 미치는 효과를 측정하였다. 측정결과, 규제로 인하여 연평균 0.58퍼센트 포인트만큼의 생산성감소효과가 있었다. 여기에는 생산성증가율 계산상의 '측정효과(測定效果)'만 존재하고 생산과정의 제약, 신규투자의 위축, 다른 생산요소의 생산성감소로 인하여 총생산성이 감소되는 '실질효과(實質效果)'는 발생하지 않았다.

• Korean Journal of Culture and Social Issue
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• v.21 no.2
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• pp.131-158
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• 2015

This study examined the relationship between physical education and externalizing(aggression) and internalizing(depression, social withdrawal) problem behaviors among adolescents. The moderating role of gender and time in the association between physical education and problem behavior was also identified. This study used data from the second, third, and fourth waves of the middle school student cohort (N=2,133, N=2,151, N=1,979) of the Korean Children-Youth Panel Survey(KCYPS). Main analyses involved multilevel growth model with interaction terms. The dependent variables were aggression, depression, and social withdrawal. The independent variables were gender and physical education (exercise hours) at school. The control variables were abuse, school-adjustment, annual household income and parents' highest level of education. The major longitudinal findings of this study are as follows: First, there was significant change according to the passage of time only in aggression among externalizing and internalizing problems. Second, gender differences exist in aggression and depression. Third, exercise hours of physical education had a negative relationship with internalizing problems. Fourth, there were no gender differences over time in both externalizing and internalizing problems. Fifth, the interaction between exercise hours of physical education and time was statistically significant for social withdrawal. Sixth, the interaction between exercise hours of physical education and gender was statistically significant for depression. The results of this study may become an academic basis for suggesting policy directions that promote increased exercise hours in physical education classes at school.

• Journal of the Korea Convergence Society
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• v.8 no.6
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• pp.275-281
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• 2017

Human endogenous retroviruses (HERVs) are fossil viruses that began to be assimilated into the human genome some 30~40 million years ago, and now constitute nearly 8% of the human genome. These ancient retroviruses have since accumulated mutations that have rendered them defective; thus, they have been termed junk DNA. However, recent research indicates that not all HERVs remain silent passengers. Although they have not been shown to be causative of any human disease, endogenous retroviral sequences may become expressed under select pathological circumstances such as neurological disorders, including multiple sclerosis (MS), schizophrenia, and Amyotrophic Lateral Sclerosis (ALS); viral infections, including human immunodeficiency virus (HIV) and herpesvirus; and multiple types of cancers. This review focused on the possible interactions of HERVs and neurological diseases.

• Proceedings of the Korean Society of Grassland Science Conference
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• 1999.06a
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• pp.78-79
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• 1999

미국으로부터 도입된 18종의 옥수수 품종과 국내품종 1종을 가지고 1997년에 경기 수원, 경북 경산 및 충남 천안에서 사일리지 생산성 비교 시험을 수행하였고, 특히 흑조위축병(RBSDV) 이병률이 옥수수의 가소화 영양소 총량(TDN)에 어느 정도 영향을 미치는가를 알아보기 위하여 일련의 조사를 수행하였다.(중략)

• The Korean journal of helicobacter and upper gastrointestinal research
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• v.18 no.4
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• pp.217-218
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• 2018

• Journal of fish pathology
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• v.20 no.1
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• pp.83-91
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• 2007

In order to differentiate the gastric tubular dilatation of olive flounder, Paralichthys olivaceus, from an atrophic change, a series of histological studies was carried out for normal gastric gland, naturally occurring and histamine-induced dilated glandular tubules. Normal glandular tubules were histologically quite similar to those already reported from other fish species. Naturally occurring, dilated gastric glandular tubules had the epithelial characteristics suffering from atrophy under light microscope, which was also the case in the histamine-induced gastric gland. But on semi-thin sections the area corresponding to the empty space of dilated lumina were actually shadowed with relatively bright area. Under transmission electron microscope this brightly shadowed area turned out to be an area tightly packed with abundant, slender cytoplasmic processes in both cases. These results strongly suggested that the dilative gastric glandular tubules under light microscope might be a morphological change indicating increased glandular activity rather than a pathologic atrophic change.

• Journal of the korean veterinary medical association
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• v.17 no.2
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• pp.25-31
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• 1981

• Journal of Yeungnam Medical Science
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• v.20 no.1
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• pp.99-103
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• 2003

Cases of coexistent lichen sclerosus et artrophicus and morphea have been reported. It is controversial that both diseases are single disease-spectrum or entirely separated. We encounterd a forty five year old female with a hypopigmented firm plaque on the left neck. Its histologic feature showed compact orthokeratosis, follicular plugging, atrophy of the stratum malpighii with vacuolar alteration of basal layer, and homogenization of the collagen in the upper dermis (lichen sclerosus et atrophicus). Increased thick collagen bundles were seen in the lower dermis (morphea).

• Journal of Labour Economics
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• v.35 no.3
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• pp.29-50
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• 2012

This paper estimates the effect of minimum wages on new hiring of low wage workers from a time-series. The results indicate that minimum wages tend to reduce the new hiring of low wage workers, in particular, among women, less educated and older population. The strongly negative effect on new hiring suggests that the burden of reduced labor demand arising from higher minimum wages tend to fall mostly upon the unprotected low-wage job searchers due to the short-term rigidity of employment adjustment among the existing workers.